標題: Titlebook: Behavioral Neuroscience of Orexin/Hypocretin; Andrew J Lawrence,Luis de Lecea Book 2017 Springer International Publishing AG 2017 orexin/h [打印本頁] 作者: Abeyance 時間: 2025-3-21 16:23
書目名稱Behavioral Neuroscience of Orexin/Hypocretin影響因子(影響力)
書目名稱Behavioral Neuroscience of Orexin/Hypocretin影響因子(影響力)學科排名
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書目名稱Behavioral Neuroscience of Orexin/Hypocretin網(wǎng)絡(luò)公開度學科排名
書目名稱Behavioral Neuroscience of Orexin/Hypocretin被引頻次
書目名稱Behavioral Neuroscience of Orexin/Hypocretin被引頻次學科排名
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書目名稱Behavioral Neuroscience of Orexin/Hypocretin讀者反饋
書目名稱Behavioral Neuroscience of Orexin/Hypocretin讀者反饋學科排名
作者: 使堅硬 時間: 2025-3-21 21:16
Orexin/Hypocretin Signaling,X. orexin receptors, as described in the previous chapters. Signaling of orexin peptides has been investigated in diverse endogenously orexin receptor-expressing cells – mainly neurons but also other types of cells – and in recombinant cells expressing the receptors in a heterologous manner. Finding作者: Suggestions 時間: 2025-3-22 02:26
Orexin/Hypocretin and Organizing Principles for a Diversity of Wake-Promoting Neurons in the Brain,ustness via redundancy’, wherein wakefulness control is not critically dependent on one type of neuron or molecule. Studies of the brain orexin/hypocretin system challenge this view by demonstrating that wakefulness control fails upon loss of this neurotransmitter system. Since orexin neurons signal作者: vitrectomy 時間: 2025-3-22 05:49
The Hypocretin/Orexin Neuronal Networks in Zebrafish,eding, sleep wake cycle, reward-seeking, addiction, and stress. Loss of Hcrt neurons causes the sleep disorder narcolepsy. The zebrafish has become an attractive model to study the Hcrt neuronal network because it is a transparent vertebrate that enables simple genetic manipulation, imaging of the s作者: 象形文字 時間: 2025-3-22 10:43
Hypocretins and Arousal, to narcolepsy has undoubtedly allowed us to advance our knowledge on key mechanisms controlling the boundaries and transitions between sleep and wakefulness. Lack of function of hypocretin neurons (a relatively simple and non-redundant neuronal system) results in inappropriate control of sleep stat作者: Arrhythmia 時間: 2025-3-22 15:30
Orexin OX2 Receptor Antagonists as Sleep Aids,and their two receptors play a major role in arousal and sleep/wake cycles. Defects in the orexin system lead to narcolepsy with cataplexy in humans and dogs and can be experimentally reproduced in rodents. At least six orexin receptor antagonists have reached Phase II or Phase III clinical trials i作者: 改正 時間: 2025-3-22 19:32
Roles for Orexin/Hypocretin in the Control of Energy Balance and Metabolism,roject widely throughout the brain and the physiologic and behavioral functions of OX are much more complex than initially conceived based upon the stimulation of feeding. OX most notably controls functions relevant to attention, alertness, and motivation. OX also plays multiple crucial roles in the作者: 教唆 時間: 2025-3-23 00:41 作者: 無思維能力 時間: 2025-3-23 04:22 作者: BLOT 時間: 2025-3-23 09:33 作者: faultfinder 時間: 2025-3-23 11:55
A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?,these neurons promotes conditioned morphine-seeking behavior. In the years since, contributions from many investigators have revealed roles for orexins in addiction for all drugs of abuse tested, but only under select circumstances. We recently proposed that orexins play a fundamentally unified role作者: grounded 時間: 2025-3-23 14:09
Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse, neurons send dense projections throughout the brain and recent observations suggest that both the intrinsic properties and the functional output of dopamine neurons are dependent on projection target and are subject to neuromodulatory influences. Lateral hypothalamic hypocretin (also termed orexin)作者: Irascible 時間: 2025-3-23 20:49 作者: blight 時間: 2025-3-24 02:07 作者: 閑逛 時間: 2025-3-24 03:54 作者: 樂章 時間: 2025-3-24 10:25
Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse,ocretin peptides act at excitatory G. protein-coupled receptors and dynorphin acts at inhibitory G. protein-coupled receptors, which are both expressed on subpopulations of dopamine neurons. This review describes a role for neuromodulation of dopamine neurons and the influence on motivated behaviour in response to natural and drug rewards.作者: 無節(jié)奏 時間: 2025-3-24 11:46 作者: 古代 時間: 2025-3-24 14:57 作者: insular 時間: 2025-3-24 22:45
What is Meant by ‘Internal Control’?d, and regulate various fundamental behaviors such as feeding, sleep, and wakefulness. Here we review how the zebrafish contributes to the study of the Hcrt neuronal system molecularly, anatomically, physiologically, and pathologically.作者: 食料 時間: 2025-3-24 23:21 作者: employor 時間: 2025-3-25 04:13
The Hypocretin/Orexin Neuronal Networks in Zebrafish,d, and regulate various fundamental behaviors such as feeding, sleep, and wakefulness. Here we review how the zebrafish contributes to the study of the Hcrt neuronal system molecularly, anatomically, physiologically, and pathologically.作者: 珊瑚 時間: 2025-3-25 11:02 作者: 迫擊炮 時間: 2025-3-25 14:48 作者: Mumble 時間: 2025-3-25 16:23 作者: Microgram 時間: 2025-3-25 21:28 作者: engender 時間: 2025-3-26 02:28
Orexin OX2 Receptor Antagonists as Sleep Aids,ng rapid eye movement (REM) and are almost devoid of effects on slow-wave (SWS) sleep. At present, there is no consensus on whether the sole promotion of REM sleep has a negative impact in patients suffering from insomnia. However, sleep onset REM (SOREM), which has been documented with DORAs, is cl作者: Pelago 時間: 2025-3-26 04:25 作者: Induction 時間: 2025-3-26 09:33 作者: 含沙射影 時間: 2025-3-26 13:49
Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders, of motivated arousal, such as depression, generally appear to be associated with hypoactivity of the orexin system. This includes narcolepsy with cataplexy, a disorder characterized by the progressive loss of orexin neurons and increased rates of moderate/severe depression symptomology. Here, we pr作者: DAFT 時間: 2025-3-26 19:21
The Role of Orexins/Hypocretins in Alcohol Use and Abuse,l (LH), perifornical (PEF), and dorsal medial (DMH) hypothalamus. These neurons project widely throughout the neuraxis with regulatory roles in a wide range of behavioral and physiological responses, including sleep–wake cycle neuroendocrine regulation, anxiety, feeding behavior, and reward seeking.作者: HPA533 時間: 2025-3-27 00:20 作者: Sinus-Rhythm 時間: 2025-3-27 01:31 作者: 無價值 時間: 2025-3-27 06:53 作者: JEER 時間: 2025-3-27 12:02 作者: 潛移默化 時間: 2025-3-27 14:30
What is Meant by ‘Internal Control’?ctances. Ohm’s law predicts that these opposite conductance changes will produce opposite effects on sensitivity of neuronal excitability to current inputs, thus enabling orexin to differentially control input-output gain of its target networks. Orexin neurons also produce other transmitters, includ作者: 柔軟 時間: 2025-3-27 21:31
Quantum-Safe Cryptography and Security,ng rapid eye movement (REM) and are almost devoid of effects on slow-wave (SWS) sleep. At present, there is no consensus on whether the sole promotion of REM sleep has a negative impact in patients suffering from insomnia. However, sleep onset REM (SOREM), which has been documented with DORAs, is cl作者: 責怪 時間: 2025-3-28 00:50 作者: 過于光澤 時間: 2025-3-28 03:06 作者: APNEA 時間: 2025-3-28 06:59 作者: 鄙視讀作 時間: 2025-3-28 13:33
https://doi.org/10.1057/9781137470348l (LH), perifornical (PEF), and dorsal medial (DMH) hypothalamus. These neurons project widely throughout the neuraxis with regulatory roles in a wide range of behavioral and physiological responses, including sleep–wake cycle neuroendocrine regulation, anxiety, feeding behavior, and reward seeking.作者: 幸福愉悅感 時間: 2025-3-28 15:13 作者: 擦試不掉 時間: 2025-3-28 19:30
Sharing Documents with Share Buttons,umulation is the main hallmark of AD pathology, while tau proteins mark brain neuronal injury due to AD pathology. Investigations so far suggest that orexinergic signaling overexpression alters the sleep–wake cycle and secondarily induces beta-amyloid accumulation and tau-mediated neurodegeneration.作者: PHONE 時間: 2025-3-28 23:57
1866-3370 advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians..978-3-319-86187-6978-3-319-57535-3Series ISSN 1866-3370 Series E-ISSN 1866-3389 作者: 粗魯性質(zhì) 時間: 2025-3-29 06:04
https://doi.org/10.1057/9780230597860retin neuropeptides. Orexins/hypocretins produced by neurons in the lateral hypothalamus stimulate their cognate GPCRs in multiple regions of the central nervous system to control sleep and arousal, circadian rhythms, metabolism, reward pathways, and other behaviors. Dysfunction of orexin/hypocretin作者: Herpetologist 時間: 2025-3-29 09:25
The Role of Auditing in an OrganizationX. orexin receptors, as described in the previous chapters. Signaling of orexin peptides has been investigated in diverse endogenously orexin receptor-expressing cells – mainly neurons but also other types of cells – and in recombinant cells expressing the receptors in a heterologous manner. Finding作者: 推延 時間: 2025-3-29 13:58
What is Meant by ‘Internal Control’?ustness via redundancy’, wherein wakefulness control is not critically dependent on one type of neuron or molecule. Studies of the brain orexin/hypocretin system challenge this view by demonstrating that wakefulness control fails upon loss of this neurotransmitter system. Since orexin neurons signal作者: 易受騙 時間: 2025-3-29 17:49 作者: moratorium 時間: 2025-3-29 21:19 作者: nonchalance 時間: 2025-3-30 03:10 作者: Cabinet 時間: 2025-3-30 07:04
Developmental Dimensions of Innovationroject widely throughout the brain and the physiologic and behavioral functions of OX are much more complex than initially conceived based upon the stimulation of feeding. OX most notably controls functions relevant to attention, alertness, and motivation. OX also plays multiple crucial roles in the作者: Intervention 時間: 2025-3-30 08:51 作者: 剛毅 時間: 2025-3-30 12:27
Moving Forward: Towards Innovative PracticeAcute stressors engage orexin neurons via direct projections from stress-sensitive brain regions. Orexin neurons, in turn, facilitate adaptive behavior via reciprocal connections as well as via direct projections to the hypophysiotropic neurons that coordinate the hypothalamic-pituitary-adrenal (HPA作者: Mechanics 時間: 2025-3-30 16:49
https://doi.org/10.1057/9781137470348diction have major social and economic consequences and cause significant morbidity and mortality worldwide. Currently available therapeutics are inadequate, outlining the need for alternative treatments. Detailed knowledge of the neurocircuitry and brain chemistry responsible for aberrant behavior 作者: ETHER 時間: 2025-3-30 22:01
Moving Forward: Towards Innovative Practicethese neurons promotes conditioned morphine-seeking behavior. In the years since, contributions from many investigators have revealed roles for orexins in addiction for all drugs of abuse tested, but only under select circumstances. We recently proposed that orexins play a fundamentally unified role
