標題: Titlebook: Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma; Juan Pedro Martinez-Barbera,Cynthia Lilian Andonia Book 2017 Sp [打印本頁] 作者: 誓約 時間: 2025-3-21 18:20
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作者: 眼界 時間: 2025-3-21 22:08
Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma978-3-319-51890-9作者: 懸掛 時間: 2025-3-22 01:06
Vladimir Stantchev,Miroslaw Malekion, morphology, migration and recurrence by the establishment of a presumably tumour stem cell niche, are discussed. Our understanding of the driving force of ACP tumourigenesis opens new avenues for targeted treatment options, e.g. the inhibition of the EGFR.作者: jeopardize 時間: 2025-3-22 08:07
High Availability and Disaster Recoverylly or transsphenoidally. The development of endoscopic transsphenoidal surgery has allowed larger and higher craniopharyngiomas to be resected safely through this route. The management of recurrent craniopharyngiomas remains challenging and may include revisional surgery or administration of interf作者: 國家明智 時間: 2025-3-22 12:32
High Availability and Disaster Recovery posterior hypothalamic areas can result in serious sequelae, mainly hypothalamic syndrome. It is crucial that craniopharyngioma can be managed as a frequently chronic disease, providing ongoing care of pediatric and adult patients by experienced multidisciplinary teams in the context of multicentre作者: Ventilator 時間: 2025-3-22 15:44 作者: 怪物 時間: 2025-3-22 19:17 作者: 過剩 時間: 2025-3-22 22:47 作者: LUMEN 時間: 2025-3-23 01:49 作者: finale 時間: 2025-3-23 06:35
Book 2017nstrated that mutations in CTNNB1 encoding -catenin underliethe etiology of the majority, if not all ACP tumors. Genetic studies in mice have shown that ACPs are tumors of the pituitary gland and not of the hypothalamus as previously thought, and are derived from Rathke’s pouch precursors. In additi作者: 勤勞 時間: 2025-3-23 10:20
iagnosis to long-term management.Includes novel and effectivThis astute volume brings together the latest expert research on adamantinomatous craniopharyngiomas (ACPs). ACPs are histologically benign but clinically aggressive tumors exhibiting a high propensity for local invasion into the hypothalam作者: 粗魯?shù)娜?nbsp; 時間: 2025-3-23 15:39 作者: 帶來 時間: 2025-3-23 19:07
High-Assurance Service Systems,vide a general overview of pituitary development, since there is strong case for a developmental origin for human ACP. We also discuss the in vitro and in vivo evidence demonstrating the presence of stem cells in the adult pituitary as well as their role of the pathogenesis of craniopharyngioma.作者: Ascribe 時間: 2025-3-24 01:38
High Availability and Disaster Recoveryadaches, nausea/vomiting, visual disturbances, growth failure (in children) and hypogonadism (in adults) being the most frequently reported. One or more pituitary hormone deficits may be already present at the time of craniopharyngioma detection in a significant number of patients necessitating early diagnosis and appropriate treatment.作者: Dawdle 時間: 2025-3-24 02:31
https://doi.org/10.1007/3-540-34582-5eep apnea. Cardiovascular risk factors need up front therapy. There is a need for centralising this rare aggressive and difficult tumour to only a few centres and that it will be managed by a multidisciplinary team with experienced neurosurgeons, endocrinologists, neurooncologists, neuroradiologists, and neuroopthamologists for a better prognosis.作者: OATH 時間: 2025-3-24 09:12 作者: Cardioplegia 時間: 2025-3-24 12:24 作者: GOUGE 時間: 2025-3-24 17:34 作者: GUISE 時間: 2025-3-24 19:39
Obesity and Metabolic Disturbances in Adamantinomatous Craniopharyngioma Patients,eep apnea. Cardiovascular risk factors need up front therapy. There is a need for centralising this rare aggressive and difficult tumour to only a few centres and that it will be managed by a multidisciplinary team with experienced neurosurgeons, endocrinologists, neurooncologists, neuroradiologists, and neuroopthamologists for a better prognosis.作者: 驕傲 時間: 2025-3-24 23:55
Radiology and Radiotherapy of Craniopharyngioma,agg peak before stopping. This phenomenon reduces the dose to adjacent critical structures and could translate into a reduction in late treatment-related sequelae and an improvement in survivors’ quality of life.作者: angina-pectoris 時間: 2025-3-25 03:30 作者: ASTER 時間: 2025-3-25 11:02 作者: 牛馬之尿 時間: 2025-3-25 13:02
Transcriptomic and Genomic Analyses of Human Craniopharyngioma,tome, while few, have raised additional therapeutic possibilities, such as potentially targeting matrix metallopeptidases. While a phase II clinical trial for targeted therapy in PCP is forthcoming, additional studies and confirmation of the current preliminary findings are required for advancing novel therapies for ACP.作者: Charade 時間: 2025-3-25 19:12
Endocrine Deficits in Patients with Human Craniopharyngioma,t familiar in managing patients with multiple endocrinopathies. Post-operatively, virtually all survivors face a lifetime risk of evolving endocrine deficits that may be extremely complex to manage, therefore requiring careful long-term follow-up and monitoring into adulthood with appropriate plans for transition between paediatric and adult care.作者: wangle 時間: 2025-3-25 23:23
https://doi.org/10.1007/3-540-34582-5illation of intracystic agents. This mode of drug delivery aims to obtain durable cyst shrinkage with minimum consequent morbidity and toxicity for patients. In this chapter we will highlight common agents used to date, paying particular attention to the drug currently gaining interest, interferon-alpha.作者: 背叛者 時間: 2025-3-26 03:35 作者: laceration 時間: 2025-3-26 04:43
https://doi.org/10.1007/978-3-319-51890-9Stem cell; adult pituitary stem cells; pituitary development; radiology; tumor biology作者: Ventricle 時間: 2025-3-26 10:56
978-3-319-84770-2Springer International Publishing AG 2017作者: 高貴領(lǐng)導 時間: 2025-3-26 14:51
Vladimir Stantchev,Miroslaw Maleka result, controversy than does the craniopharyngioma”. This statement clarifies the situation of medical specialists such as endocrinologists, neurosurgeons, neuropathologists, neurooncologists, paediatric oncologists and neuro-radiologists involved in treatment of craniopharyngioma (CP) patients. 作者: MIRTH 時間: 2025-3-26 20:26 作者: 反叛者 時間: 2025-3-26 22:19
High-Assurance Service Systems,obal and gene-specific expression studies of human biopsies have helped to delineate the network of pathways involved in the initiation and establishment of these tumours. Interestingly, genetically modified and patient-derived xenograft mouse models have revealed the function of some of the dysregu作者: MILK 時間: 2025-3-27 03:06 作者: Nausea 時間: 2025-3-27 07:11 作者: 生氣地 時間: 2025-3-27 10:35
https://doi.org/10.1007/3-540-34582-5 rate in CP is high and therapy of choice is surgery, followed by cranial radiotherapy (CRT) in about half of the patients. Patients with CP have a 3–19 fold higher cardiovascular mortality in comparison to the general population. The majority of patients have an extended hypopituitarism that needs 作者: confide 時間: 2025-3-27 15:41 作者: 完整 時間: 2025-3-27 20:18
High Availability and Disaster Recoveryy pressure and distortion of the optic nerves and chiasm, the hypothalamus and the pituitary gland. Involvement of the third ventricle causes hydrocephalus. Initial management is surgical and directed towards preservation of vision and control of raised intracranial pressure. Further surgical manage作者: Servile 時間: 2025-3-28 01:05
https://doi.org/10.1007/3-540-34582-5sial with persisting high morbidity rates for those affected. As such, there continues to be a scope for therapeutic improvements and innovation in the field. The cystic composition of adamantinomatous craniopharyngiomas (ACPs) makes them an ideal candidate to evaluate one such development; the inst作者: 共同確定為確 時間: 2025-3-28 05:14
High Availability and Disaster Recoveryregard to clinical trials and long-term management. Craniopharyngiomas are rare, embryonic malformations of the sellar/parasellar region with low histological grade. Clinical manifestations are related to increased intracranial pressure, visual impairment, and hypothalamic/pituitary deficiencies. If作者: 增強 時間: 2025-3-28 07:30
Juan Pedro Martinez-Barbera,Cynthia Lilian AndoniaThe first book to target current research on adamantinomatous craniopharyngiomas (ACPs).Topics covered range from pathogenesis to clinical diagnosis to long-term management.Includes novel and effectiv作者: 人類的發(fā)源 時間: 2025-3-28 13:37 作者: Insensate 時間: 2025-3-28 16:00
Pathogenesis of Human ACP,a result, controversy than does the craniopharyngioma”. This statement clarifies the situation of medical specialists such as endocrinologists, neurosurgeons, neuropathologists, neurooncologists, paediatric oncologists and neuro-radiologists involved in treatment of craniopharyngioma (CP) patients. 作者: Mundane 時間: 2025-3-28 22:33
Transcriptomic and Genomic Analyses of Human Craniopharyngioma,. Genomic studies of adamantinomatous craniopharyngioma (ACP) have revealed mutations in the . gene, resulting in nuclear and cytoplasmic accumulation of β-catenin protein. Papillary craniopharyngioma (PCP), however, is characterised by the BRAF V600E mutation, which suggests novel therapeutic strat作者: 強制令 時間: 2025-3-29 01:00 作者: 多樣 時間: 2025-3-29 03:11
Clinical Diagnosis of Human ACP, intracranial tumours in children. The adamantinomatous histological subtype is the most common and the majority of them (94–95%) have a suprasellar component. Their potential proximity to, and the subsequent pressure effects on vital structures of the brain (visual pathways, brain parenchyma, ventr作者: 移植 時間: 2025-3-29 10:42
Endocrine Deficits in Patients with Human Craniopharyngioma,from tumour- and treatment-related effects. Endocrine deficits are frequently present at diagnosis but are often under-recognised; thus a detailed pre-treatment endocrine assessment is essential, particularly to exclude adrenocorticotrophic hormone deficiency and central diabetes insipidus prior to 作者: BAIL 時間: 2025-3-29 12:31
Obesity and Metabolic Disturbances in Adamantinomatous Craniopharyngioma Patients, rate in CP is high and therapy of choice is surgery, followed by cranial radiotherapy (CRT) in about half of the patients. Patients with CP have a 3–19 fold higher cardiovascular mortality in comparison to the general population. The majority of patients have an extended hypopituitarism that needs 作者: 偏離 時間: 2025-3-29 16:08 作者: CHASE 時間: 2025-3-29 23:02
Surgical Treatment of Human ACP,y pressure and distortion of the optic nerves and chiasm, the hypothalamus and the pituitary gland. Involvement of the third ventricle causes hydrocephalus. Initial management is surgical and directed towards preservation of vision and control of raised intracranial pressure. Further surgical manage
