標題: Titlebook: Basic Aspects of Receptor Biochemistry; Proceedings of the I Menek Goldstein,Kurt Jellinger,Peter Riederer Conference proceedings 1983 Spri [打印本頁] 作者: Causalgia 時間: 2025-3-21 19:35
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書目名稱Basic Aspects of Receptor Biochemistry讀者反饋
書目名稱Basic Aspects of Receptor Biochemistry讀者反饋學科排名
作者: llibretto 時間: 2025-3-21 23:39
Interactions of Ergot Compounds with Dopamine Receptors and Endocrine Functions,t cases, with the exception of the prolactin and the melanotropin cell receptors, the characterization of the dopamine receptor involved is not yet satisfactory. Comparing . or . dopaminomimetic activities of ergot compounds produces a multiplicity of profiles of actions without a clear pattern.作者: 比喻好 時間: 2025-3-22 02:31
Basic Aspects of Receptor Biochemistry978-3-7091-4408-4Series ISSN 0303-6995 作者: 一再困擾 時間: 2025-3-22 06:38 作者: handle 時間: 2025-3-22 10:28
https://doi.org/10.1007/978-3-662-50325-6t cases, with the exception of the prolactin and the melanotropin cell receptors, the characterization of the dopamine receptor involved is not yet satisfactory. Comparing . or . dopaminomimetic activities of ergot compounds produces a multiplicity of profiles of actions without a clear pattern.作者: 凝結劑 時間: 2025-3-22 16:13 作者: Myofibrils 時間: 2025-3-22 17:57 作者: Defense 時間: 2025-3-23 00:06 作者: 騎師 時間: 2025-3-23 04:21
https://doi.org/10.1007/978-3-642-45967-2tum after in vivo administration and high-resolution radioautography. Since this ligand does not cross the blood-brain barrier, intracerebral injections were performed, which resulted in a gradient of diffusion of the tracer. According to increasing distances to the injection site, a quantitative st作者: 搏斗 時間: 2025-3-23 06:08
Stilwechsel und Bewu?tseinswandeltibodies to tyrosine hydroxylase (TH) to provide an atlas of human catecholaminergic (CA) neurons. A striking increase in complexity of CA neurons is seen in the human mesencephalon when compared with lower animals. Not only synthetic enzymes but also neurotransmitters themselves can be detected. An作者: 是突襲 時間: 2025-3-23 11:49
Gedanken über die Zukunft der Philosophiey by marker enzyme determination, light and electron microscopy. Binding properties of .H-flunitrazepam were studied in different brain regions. Kinetic studies of .H-flunitrazepam showed B. values of 0,42 ± 0,3 pmol/mg protein and K.-values of 1,26 ± 0,6 nM and were compared to a synaptosomal membr作者: foppish 時間: 2025-3-23 17:55
150 Jahre Heidelberger Chirurgieds to synaptic membranes. However, biochemical and physico-chemical properties of such binding sites (receptors) are not fully understood. Therefore, a number of partly contradictory biochemical models have been developed. The physico-chemical properties of the chemical structures involved are usual作者: 后天習得 時間: 2025-3-23 20:23 作者: 剛開始 時間: 2025-3-24 01:08
Eichendorff, Heidelberg und die Blaue Blumeo interacts with systems which act to remove the substance. At no time is there an equilibrium, and it is inappropriate to apply equilibrium kinetics to predict the consequences of modifying the system, .. by blocking receptors. A mathematical model predicts that the subsynaptic response to each pac作者: Synapse 時間: 2025-3-24 02:28 作者: ICLE 時間: 2025-3-24 10:09 作者: 使混合 時間: 2025-3-24 12:59
Gründe und Grenzen der Strafbarkeitxperiments in the rat hippocampus demonstrate the axonal transport of A derivatives to nerve endings with subsequent stimulus-dependent release. Analysis of the material released from central tissues on electrical stimulation indicates that at least a proportion of the A derivatives collected are re作者: CANDY 時間: 2025-3-24 16:42
Das Diakoniewissenschaftliche Institutability of NE and the formation of the NE receptor complex is one prerequisite for the regulation of both the sensitivity of the system and the density of its .-adrenoceptor population. Serotonergic neuronal input is corequired with NE for the down-regulation of the number of .-adrenoceptors, which 作者: 個阿姨勾引你 時間: 2025-3-24 22:28 作者: 吞吞吐吐 時間: 2025-3-25 02:53 作者: LEERY 時間: 2025-3-25 03:44
Generationenprobleme im Alten Testamento states. The D. state is characterized by its nM affinity for dopamine. The D. state is typified by its .M affinity for dopamine. Neuroleptics have the same affinity (50 pM for spiperone) for both states. Guanine nucleotides convert most, if not all, of the D. sites into D. sites. Any D. sites whic作者: Mirage 時間: 2025-3-25 10:44
Wie das Bild der Atomkerne Sichtbar wurde,receptors are detected. When the thioxanthene neuroleptics .H-cis (Z)-flupenthixol or .H-piflutixol are used as ligands D-1 receptors coupled to adenylate cyclase can be detected. In displacement experiments butyrophenones (haloperidol and spiroperidol) and diphenylbutylpiperidines (pimozide) intera作者: 煩人 時間: 2025-3-25 12:43 作者: acquisition 時間: 2025-3-25 19:10
https://doi.org/10.1007/978-3-662-50325-6, phenylephrine, clonidine and phentolamine has been found to produce a normal ergometrine-induced hyperactivity. In contrast, low doses of dopamine and (3,4-dihydroxyphenylimino)-2-imidazoline (DPI) and only high doses of clonidine and phentolamine have been found to attenuate the ergometrine respo作者: ineluctable 時間: 2025-3-26 00:00 作者: freight 時間: 2025-3-26 01:00
https://doi.org/10.1007/978-3-322-85712-5nsitivity. This effect may be of functional significance in the whole animal for it is accompanied by increased striatal acetylcholine content and by reversal of the acute increase in striatal acetylcholine release..Continuous drug intake may increase the number of striatal .H-spiperone binding site作者: 蔓藤圖飾 時間: 2025-3-26 04:30
High-Resolution Radioautographic Study of Dopamine Binding Sites in the Rat Neostriatum Using 3H-Dooreover half of these labelled contacts were differentiated in synapses of the asymmetric type. When the animals were pretreated with haloperidol in order to block the dopaminergic binding sites, we found a decrease in the total number of the number of silver grains. A decrease in the number of clus作者: 吹氣 時間: 2025-3-26 11:18 作者: 愛管閑事 時間: 2025-3-26 14:51
Coordination Chemical Aspects of Receptor Biochemistry,polar groups form a three dimensional network, in which EPD sites (of the polar groups) interact with EPA sites..We have used this model to explain some of the interactions between 5-hydroxytryptamine (5-HT), the “5-HT receptor”, NH. and L-valine. As the rate of 5-HT binding increases at higher temp作者: alleviate 時間: 2025-3-26 20:26
Energetics of Ligand Binding to Receptors,lysis, is highlighted. Given a series of closely related ligands it is possible to estimate the energetic contributions of substituent groups not only to the binding affinity to the receptor but also to the induction of conformational change in the receptor provided that the rate of conformational c作者: nephritis 時間: 2025-3-26 22:32 作者: 商業(yè)上 時間: 2025-3-27 03:55
Calmodulin, Ca2+-Antagonists and Ca2+-Transporters in Nerve and Muscle,t from the antiporter of heart mitochondria. These results are discussed in terms of Ca.-binding proteins being potential targets for pharmacological interventions designed to block specific aspects of the action of calcium.作者: initiate 時間: 2025-3-27 07:08 作者: neolith 時間: 2025-3-27 12:53
Regulation of Noradrenergic Receptor Systems in Brain that Are Coupled to Adenylate Cyclase,ological responsiveness of NE receptor systems, the number of receptors and the efficacy of their coupling to adenylate cyclase appear to represent control mechanisms for the intensity of signal transfer.作者: 鴕鳥 時間: 2025-3-27 14:02
The Search for Selective Dopaminergic Autoreceptor Agonists, and it is suggested that compounds such as (?)-3-PPP may find future clinical application as “second-generation” antipsychotic agents, lacking in the debilitating motor side effects produced by drugs in current therapeutic use.作者: 整潔漂亮 時間: 2025-3-27 18:23
Evidence That the D-2 Dopamine Receptor in the Intermediate Lobe of the Rat Pituitary Gland Is Assonylate cyclase activity; apomorphine, a dopaminergic agonist, abolishes this effect of GTP. It is hypothesized that the D-2 dopamine receptor in the IL interacts with an inhibitory guanyl nucleotide component (N.); stimulation of the D-2 dopamine receptor alters the properties of N. so that N. can i作者: BACLE 時間: 2025-3-28 00:29 作者: 姑姑在炫耀 時間: 2025-3-28 04:37
,Evidence for the Existence of Receptor—Receptor Interactions in the Central Nervous System. Studies change the characteristics of the .H-N-propylnorapomorphine (.H-NPA) binding sites in striatal membranes of rats. Glutamate (10. M) increases the density and especially reduces the affinity of the .H-NPA binding sites, which label D. and D. types of DA receptors..Taken together the present findings作者: scrape 時間: 2025-3-28 10:20
Long-Term Adaptive Changes in Striatal Dopamine Function in Response to Chronic Neuroleptic Intake g on striatal cell bodies and on the terminals of cortico-striate glutamate terminals..In summary, neuroleptic drugs induce a series of adaptive changes on chronic administration consistent with the development of functional striatal dopamine receptor supersensitivity.作者: mediocrity 時間: 2025-3-28 10:25
https://doi.org/10.1007/978-3-642-45967-2oreover half of these labelled contacts were differentiated in synapses of the asymmetric type. When the animals were pretreated with haloperidol in order to block the dopaminergic binding sites, we found a decrease in the total number of the number of silver grains. A decrease in the number of clus作者: Bureaucracy 時間: 2025-3-28 18:08 作者: cataract 時間: 2025-3-28 19:16 作者: 彩色的蠟筆 時間: 2025-3-29 00:37 作者: 強行引入 時間: 2025-3-29 05:38
Eichendorff, Heidelberg und die Blaue Blumeiature end-plate current, .. the action of a quantum if nerve-released acetylcholine (ACh), by 50%. On the other hand, drugs that interfere with receptor function without preventing ACh binding to receptors can be just as (or more) effective in blocking nerve-applied as in blocking exogenously appli作者: 親密 時間: 2025-3-29 09:12
https://doi.org/10.1007/978-3-642-46021-0t from the antiporter of heart mitochondria. These results are discussed in terms of Ca.-binding proteins being potential targets for pharmacological interventions designed to block specific aspects of the action of calcium.作者: cumulative 時間: 2025-3-29 12:46 作者: 小畫像 時間: 2025-3-29 15:38
Das Diakoniewissenschaftliche Institutological responsiveness of NE receptor systems, the number of receptors and the efficacy of their coupling to adenylate cyclase appear to represent control mechanisms for the intensity of signal transfer.作者: HAWK 時間: 2025-3-29 22:31 作者: myopia 時間: 2025-3-30 00:48
Richard Rothes Berufung Nach Heidelberg 1837nylate cyclase activity; apomorphine, a dopaminergic agonist, abolishes this effect of GTP. It is hypothesized that the D-2 dopamine receptor in the IL interacts with an inhibitory guanyl nucleotide component (N.); stimulation of the D-2 dopamine receptor alters the properties of N. so that N. can i作者: 動物 時間: 2025-3-30 04:55
Wie das Bild der Atomkerne Sichtbar wurde,st unchanged. When mice are treated for 12 days with neuroleptics, supersensitivity to methylphenidate is induced. The supersensitivity is reversed by thioxanthenes, whereas butyrophenones and diphenylbutylpiperidines have no effect at all. These differenes do not appear to be due to a change in the作者: 個阿姨勾引你 時間: 2025-3-30 09:53 作者: 卵石 時間: 2025-3-30 16:02 作者: 細菌等 時間: 2025-3-30 18:23 作者: Alveolar-Bone 時間: 2025-3-31 00:13 作者: 剝削 時間: 2025-3-31 02:02
Neurotransmitter Related Immunocytochemistry of the Human Central Nervous System,tibodies to tyrosine hydroxylase (TH) to provide an atlas of human catecholaminergic (CA) neurons. A striking increase in complexity of CA neurons is seen in the human mesencephalon when compared with lower animals. Not only synthetic enzymes but also neurotransmitters themselves can be detected. An作者: 預兆好 時間: 2025-3-31 05:42
Studies on the Neurotransmitter Binding to Pig Brain Microvessels,y by marker enzyme determination, light and electron microscopy. Binding properties of .H-flunitrazepam were studied in different brain regions. Kinetic studies of .H-flunitrazepam showed B. values of 0,42 ± 0,3 pmol/mg protein and K.-values of 1,26 ± 0,6 nM and were compared to a synaptosomal membr作者: LOPE 時間: 2025-3-31 10:26 作者: 伴隨而來 時間: 2025-3-31 14:31
Energetics of Ligand Binding to Receptors, changes in the receptors that this induces. Although the effects of chemical modifications of ligands on their affinity for receptors have been intensively studied in several systems, the influence of such changes upon the ability of ligands to induce the conformational changes in receptors that ar作者: 熔巖 時間: 2025-3-31 21:18
Receptor Blockade and Synaptic Function,o interacts with systems which act to remove the substance. At no time is there an equilibrium, and it is inappropriate to apply equilibrium kinetics to predict the consequences of modifying the system, .. by blocking receptors. A mathematical model predicts that the subsynaptic response to each pac作者: Commission 時間: 2025-4-1 00:23 作者: debouch 時間: 2025-4-1 05:37
Calmodulin, Ca2+-Antagonists and Ca2+-Transporters in Nerve and Muscle,s binding and activation of various Ca.-binding proteins (CBP), including those in the Ca. channel, the Na.-Ca. antiporter, and intracellular calmodulin (CDR). Generally, Ca.-binding to regulatory CBP exposes hydrophobic sites on their surface at which the CBP interfaces with its receptor or binds i作者: Graphite 時間: 2025-4-1 07:07 作者: 語源學 時間: 2025-4-1 10:25 作者: Indicative 時間: 2025-4-1 17:31
The Search for Selective Dopaminergic Autoreceptor Agonists,esolved into its dextro-(+) and levo-(?) rotatory enantiomers. The compounds were pharmacologically evaluated by means of behavioural and biochemical methods. Surprisingly, both (+)- and (?)-3-PPP show clearcut, but differential, effects on the DA receptors. Thus, (+)-3-PPP is a DA receptor agonist
