作者: 感情 時(shí)間: 2025-3-21 23:24
Structure of the Lipopolysaccharide Core Region,ral, the LPS may be present either in the smooth form (S, possessing the polysaccharide region) or in the rough form (R, lacking the polysaccharide, also called lipooligosaccharide, LOS). Both forms contain lipid A [.] and a core oligosaccharide (OS) that comprises up to 15 sugar residues [.–.].作者: acrimony 時(shí)間: 2025-3-22 02:10 作者: mighty 時(shí)間: 2025-3-22 04:59 作者: Neutropenia 時(shí)間: 2025-3-22 11:29 作者: adulterant 時(shí)間: 2025-3-22 16:19
Genetics and Biosynthesis of Lipid A,, therefore, in constant contact with the surrounding environment. The Gram-negative outer membrane is unique as compared to most biological membranes in that it is an asymmetric bilayer composed of a phospholipid inner leaflet and a lipopolysaccharide (LPS) outer leaflet as opposed to a symmetrical作者: 同位素 時(shí)間: 2025-3-22 19:09 作者: commute 時(shí)間: 2025-3-22 23:16 作者: 抱狗不敢前 時(shí)間: 2025-3-23 02:00
Genetics, Biosynthesis and Assembly of O-Antigen,charide (OS), and O-specific polysaccharide or O-antigen [1,2]. LPS is a surface molecule unique to Gram-negative bacteria that plays a key role as an elicitor of innate immune responses, ranging from localized inflammation to disseminated sepsis [3]. The O-antigen, which is the most surface-exposed作者: libertine 時(shí)間: 2025-3-23 09:19 作者: annexation 時(shí)間: 2025-3-23 10:45 作者: Urologist 時(shí)間: 2025-3-23 14:50 作者: extrovert 時(shí)間: 2025-3-23 19:35
Lipopolysaccharide and Its Interactions with Plants,sing and rapidly mounted defence responses. Such protective mechanisms are found in all multicellular organisms and are collectively referred to as innate immunity. Innate immunity is the first line of defence against invading microorganisms in vertebrates and the only line of defence in invertebrat作者: Increment 時(shí)間: 2025-3-24 01:29
Structure of O-Antigens,al properties help improving classification schemes of Gram-negative bacteria. Furthermore, these studies contributed to a better understanding of the mechanisms of pathogenesis of infectious diseases, as well as provided information to develop novel vaccines and diagnostic reagents.作者: 值得贊賞 時(shí)間: 2025-3-24 03:15
cules has recently attracted the attention of many investigators, in particular for understanding its involvement in innate immunity, toll-like receptor recognition and intracellular signaling. .978-3-7091-1693-7978-3-7091-0733-1作者: Germinate 時(shí)間: 2025-3-24 09:46 作者: 臨時(shí)抱佛腳 時(shí)間: 2025-3-24 12:54
Yuriy A. Knirel,Miguel A. ValvanoUpdates the current knowledge concerning the lipopolysaccharide.New aspects of their physicochemical biology are introduced.Emphasis is placed on the fine chemical structure.Includes supplementary mat作者: 規(guī)范就好 時(shí)間: 2025-3-24 17:24
http://image.papertrans.cn/b/image/180295.jpg作者: 比目魚 時(shí)間: 2025-3-24 19:20 作者: Glaci冰 時(shí)間: 2025-3-25 00:16
https://doi.org/10.1007/0-306-48402-1In this chapter we will discuss how lipopolysaccharide (LPS) is transported and assembled from its site of synthesis (the cytoplasm and the inner membrane) to the cell surface. This is a remarkably complex process, as LPS must traverse three different cellular compartments to reach its final destination.作者: Blasphemy 時(shí)間: 2025-3-25 03:55 作者: 提煉 時(shí)間: 2025-3-25 11:22 作者: 雜色 時(shí)間: 2025-3-25 11:42 作者: expository 時(shí)間: 2025-3-25 19:30 作者: 障礙物 時(shí)間: 2025-3-25 23:20 作者: 大包裹 時(shí)間: 2025-3-26 01:07 作者: 聯(lián)合 時(shí)間: 2025-3-26 06:52
Biological Retrospective Dosimetrydded in the membrane and serves as an anchor for the rest of the LPS molecule. The outermost repetitive glycan region of the LPS is linked to the lipid A through a core oligosaccharide (OS), and is designated as the O-specific polysaccharide (O-polysaccharide, OPS) or O-antigen. The O-antigen is the作者: conscience 時(shí)間: 2025-3-26 09:45 作者: BRUNT 時(shí)間: 2025-3-26 15:11 作者: 凹室 時(shí)間: 2025-3-26 20:33 作者: MUTE 時(shí)間: 2025-3-26 22:52 作者: 冥界三河 時(shí)間: 2025-3-27 03:54 作者: Mets552 時(shí)間: 2025-3-27 06:12
Probing, Inspection, Monitoringcharide (OS), and O-specific polysaccharide or O-antigen [1,2]. LPS is a surface molecule unique to Gram-negative bacteria that plays a key role as an elicitor of innate immune responses, ranging from localized inflammation to disseminated sepsis [3]. The O-antigen, which is the most surface-exposed作者: certitude 時(shí)間: 2025-3-27 12:38
https://doi.org/10.1007/0-306-48402-1ligosaccharide (OS), and O-specific antigen in the order in which they occur in LPS, which correlates with increasing structural diversity for each component. In ., for example, there are five core OS types known and over 180 O-antigen forms (including .), and in ., 2 and 46 respectively. The divers作者: Antimicrobial 時(shí)間: 2025-3-27 16:08 作者: 組裝 時(shí)間: 2025-3-27 19:10
https://doi.org/10.1007/0-306-48402-1in therapeutic manipulation of innate immune system. In this chapter, several natural and synthetic molecules that modulate the TLR4-mediated LPS signalling in animals and humans are presented, and their mechanisms of action are discussed. The synthetic or natural TLR4 modulators will be grouped as:作者: 輕推 時(shí)間: 2025-3-28 01:44
https://doi.org/10.1007/0-306-48402-1sing and rapidly mounted defence responses. Such protective mechanisms are found in all multicellular organisms and are collectively referred to as innate immunity. Innate immunity is the first line of defence against invading microorganisms in vertebrates and the only line of defence in invertebrat作者: 暫時(shí)別動(dòng) 時(shí)間: 2025-3-28 06:10
Probing, Inspection, Monitoring phospholipid bilayer (Fig.?6.1). The presence of LPS in the outer leaflet confers unique properties to the membrane including an efficient permeability barrier that affords Gram-negative bacteria additional protection from their surrounding environment.作者: GLEAN 時(shí)間: 2025-3-28 07:22 作者: LIEN 時(shí)間: 2025-3-28 13:02
Probing, Inspection, Monitoringprenyl-diphosphate-carried OPS is joined by a carbon-oxygen ligase onto lipid A core and the resulting completed LPS molecule is shuffled onto outer membrane by the recently delineated Lpt translocation pathway.作者: 使害怕 時(shí)間: 2025-3-28 16:05
Probing, Inspection, Monitoring LPS moiety, also contributes to pathogenicity by protecting invading bacteria from bactericidal host responses [2]. A detailed understanding of the biosynthesis of the LPS O-antigen may contribute to identifying new means to curtail infections by interfering with its assembly.作者: 歌劇等 時(shí)間: 2025-3-28 19:01
https://doi.org/10.1007/0-306-48402-1ity of O-antigen forms has been widely studied for some species although the forms known may be underestimates as most of the isolates typed are from humans or domestic animals and their associated environments.作者: profligate 時(shí)間: 2025-3-29 00:27
https://doi.org/10.1007/0-306-48402-1 compounds binding and sequestering LPS; compounds targeting LBP and CD14/LPS interaction; compounds targeting LPS/MD-2 or LPS/MD-2/TLR4 interaction; compounds directly targeting TLR4; and finally molecules modulating TLR4 activity whose exact target(s) are not yet elucidated.作者: 不透氣 時(shí)間: 2025-3-29 05:53
ed on the fine chemical structure.Includes supplementary mat.The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemical structure of the lipopolysaccharide and its significance for understanding their activi作者: TAIN 時(shí)間: 2025-3-29 09:20 作者: 鉗子 時(shí)間: 2025-3-29 12:36
Ionizing Radiation Measurements,xclude the possibility of influence by contaminants from bacterial or other sources. In this chapter, representative synthetic work on lipid A and analogues will be outlined with brief explanations of their significance for endotoxin research.作者: esthetician 時(shí)間: 2025-3-29 17:57 作者: 變形詞 時(shí)間: 2025-3-29 22:59
Lipid A Structure,organisms living in habitats that are unusual for most other organisms, such as high salinity or pressure, extreme temperatures and critic pH. Bacteria include saprophytic and pathogenic species. They are divided into Gram-negative and Gram-positive bacteria based on the Gram stain, which reflects differences in the cell envelope architecture.作者: hypotension 時(shí)間: 2025-3-30 01:54
Chemical Synthesis of Lipid A and Analogues,xclude the possibility of influence by contaminants from bacterial or other sources. In this chapter, representative synthetic work on lipid A and analogues will be outlined with brief explanations of their significance for endotoxin research.作者: 反話 時(shí)間: 2025-3-30 05:35 作者: Phenothiazines 時(shí)間: 2025-3-30 10:08
Biological Retrospective Dosimetry suitable glycosyl donors and acceptor derivatives for the assembly of inner and outer core units. Major synthetic accomplishments covering core structures from ., ., ., ., ., . and . LPS are described in this review.作者: Progesterone 時(shí)間: 2025-3-30 13:04
Chemical Synthesis of Lipopolysaccharide Core, suitable glycosyl donors and acceptor derivatives for the assembly of inner and outer core units. Major synthetic accomplishments covering core structures from ., ., ., ., ., . and . LPS are described in this review.作者: Entreaty 時(shí)間: 2025-3-30 20:18 作者: 顛簸下上 時(shí)間: 2025-3-30 23:18
Lipopolysaccharide and Its Interactions with Plants,ell wall strengthening and pathogenesis-related (PR) protein accumulation, leading to basal resistance or innate immunity. Recognition of non-self, such as an invading pathogen, is crucial for an effective defence response.作者: 山頂可休息 時(shí)間: 2025-3-31 03:49 作者: 赦免 時(shí)間: 2025-3-31 08:47
Genetics and Biosynthesis of Lipid A, phospholipid bilayer (Fig.?6.1). The presence of LPS in the outer leaflet confers unique properties to the membrane including an efficient permeability barrier that affords Gram-negative bacteria additional protection from their surrounding environment.作者: 退潮 時(shí)間: 2025-3-31 09:18
Pathways for the Biosynthesis of NDP Sugars,uding neutral sugars, charged sugars that are acidic or amino substituted (see Chap. 3). Substitutions and enzymatic modifications of the basic sugar structure also lead to interesting deoxy or dideoxy sugars.
