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標(biāo)題: Titlebook: Application of Nanocarriers in Brain Delivery of Therapeutics; Amit Alexander Book 2024 The Editor(s) (if applicable) and The Author(s), u [打印本頁(yè)]

作者: JOLT    時(shí)間: 2025-3-21 16:29
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作者: perjury    時(shí)間: 2025-3-21 21:06
978-981-97-2861-9The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
作者: Awning    時(shí)間: 2025-3-22 02:54
Amit AlexanderPresents nanocarriers as potential drug delivery candidates for overcoming the blood-brain barrier.Introduces different cell lines and animal models involved in brain research.Discusses nanoparticulat
作者: confederacy    時(shí)間: 2025-3-22 07:51
http://image.papertrans.cn/b/image/167490.jpg
作者: 啞巴    時(shí)間: 2025-3-22 10:04

作者: Preserve    時(shí)間: 2025-3-22 14:54
https://doi.org/10.1007/3-540-15653-4S) microenvironment. This is essential for maintaining the brain in optimal functioning conditions. The BBB is composed of endothelial cells lining the brain microvessels, while the BCSFB is formed by the choroid plexus epithelial cells. These barriers regulate the passage of both cells and molecule
作者: 說笑    時(shí)間: 2025-3-22 18:55

作者: BRINK    時(shí)間: 2025-3-22 21:25
Hadrons in Dense Matter and Hadrosynthesisns. Reaching the brain is truly arduous for the therapeutic moieties due to the BBB and other protective measures. A series of diverse nanocarrier systems and novel approaches have been explored to deliver bioactives to the brain effectively. Polymeric nanoparticles embrace significant capabilities
作者: FECT    時(shí)間: 2025-3-23 02:40

作者: Nebulous    時(shí)間: 2025-3-23 08:57
https://doi.org/10.1007/978-94-015-8175-2harmacodynamic and pharmacokinetic profile of concerned drugs. In this view, the nanotechnology can play a significant role to overcome the stated problem. Recently, nanoparticles are dragging lots of interest as nanodelivery system carries the drug into the brain because it provide stability for dr
作者: 過時(shí)    時(shí)間: 2025-3-23 12:48

作者: Engaged    時(shí)間: 2025-3-23 15:10
S. Pujithaa,M. Rajamiriyam,M. K. Kalaivaniobe. As per statistics, approximately 1 in 60 Americans suffer from Alzheimer’s, and at least half a million Americans suffer from Parkinson’s. The high selectivity nature of the blood–brain barrier (BBB) prohibits the entry of all large molecules and nearly all small molecules into the brain. A phy
作者: hereditary    時(shí)間: 2025-3-23 18:02
T. S. Kumar,A. Josephine,G. Dharanis, memory, mood, and emotional behavior of affected people and are the second leading sources of deaths across the globe. The current treatments with the conventional delivery systems alleviate the symptoms of these disorders and fail to achieve sufficient drug concentration in the brain which ultim
作者: 我就不公正    時(shí)間: 2025-3-23 22:59

作者: 皮薩    時(shí)間: 2025-3-24 05:00
Bahar Aslanbay Guler,Esra Imamoglucell line models for brain research. These models encompass a wide array of neuronal and glial cell lines, primary cultures, and sophisticated systems that closely mimic the brain’s intricate microenvironments. They have become invaluable tools for investigating various facets of brain biology and p
作者: 口訣    時(shí)間: 2025-3-24 07:12

作者: Celiac-Plexus    時(shí)間: 2025-3-24 14:21
Anticoagulation For Haemodialysis,he nanocarriers derived from metals, polymers, and other materials have shown their therapeutic efficacy against several neurological disorders during in vitro and preclinical studies. However, these nanocarriers, especially metal and silica NPs, have shown their toxicity against neuronal cell lines
作者: 發(fā)炎    時(shí)間: 2025-3-24 15:52

作者: instulate    時(shí)間: 2025-3-24 19:23
Book 2024s complex brain disorders, the currently available therapies, and their limitations. The book discusses the potential applications of polymeric nanoparticles, lipid nanocarriers, liposomes, inorganic nanoparticles, dendrimers, and stimuli-responsive polymers for targeted brain drug delivery. Further
作者: Debate    時(shí)間: 2025-3-25 00:48
Safety, Stability Concerns, and Regulatory Aspects of Nanocarriers for Brain Delivery, via the generation of reactive oxygen species, astrogliosis, and downregulation of glutathione. The discrepancies in the result may be due to their size, surface chemistry, and shape. The interaction between nanocarriers and living systems is not clear. These factors limit the safety and regulation of nanocarriers.
作者: occult    時(shí)間: 2025-3-25 03:33
Anticoagulation For Haemodialysis, via the generation of reactive oxygen species, astrogliosis, and downregulation of glutathione. The discrepancies in the result may be due to their size, surface chemistry, and shape. The interaction between nanocarriers and living systems is not clear. These factors limit the safety and regulation of nanocarriers.
作者: 變色龍    時(shí)間: 2025-3-25 07:58
Book 2024ety, toxicity, regulatory aspects, future possibilities, and constraints in the clinical translation of nanocarrier systems to treat neurological disorders. The book as such provides valuable information to neuroscientists, and researchers working in pharmaceuticals, nanomedicine, drug delivery research, and nanotechnology..?
作者: ASSET    時(shí)間: 2025-3-25 13:34
Quark models of hadronic interactions,s associated with these medications often worsen the quality of life and enhance the socioeconomic burden on patients, which necessitates further studies to explore safer and effective management options for complex brain disorders.
作者: Hyperplasia    時(shí)間: 2025-3-25 18:27

作者: BACLE    時(shí)間: 2025-3-25 22:46

作者: Explosive    時(shí)間: 2025-3-26 03:12
New Clinical Applications: Nephrologyn drug delivery. In this chapter, we have highlighted the current clinical advancements of nanocarrier-based formulations for the treatment of neurodegenerative disorders, ongoing clinical studies, and challenges in clinical translation.
作者: Complement    時(shí)間: 2025-3-26 04:52
Introduction to Complex Brain Disorders, Currently Available Therapies, and Their Limitations,s associated with these medications often worsen the quality of life and enhance the socioeconomic burden on patients, which necessitates further studies to explore safer and effective management options for complex brain disorders.
作者: OWL    時(shí)間: 2025-3-26 10:56
Challenges of Brain Targeting and Mechanism of Drug Transfer Across Brain Barriers,is responsible for the high drug doses prescribed to increase the bioavailability in the site of action and consequently the rise in side effects. Thus, brain-targeting drug delivery systems will provide new methodologies for an efficient drug delivery across the brain barriers.
作者: MAL    時(shí)間: 2025-3-26 14:07
Potential of Dendrimers as Nanocarrier for Brain Delivery,g several therapeutic delivery strategies in the last few decades. This chapter focuses on the potential of dendrimers in treating cancer, as well as other neurological diseases. Dendrimers have a cascade framework that can be anchored with a many targeting moiety for reflexive trapping and on demand drug release at site of interest.
作者: esoteric    時(shí)間: 2025-3-26 19:56
Current Clinical Advancements of Nanocarriers for Brain Targeting and Limitations in Clinical Transn drug delivery. In this chapter, we have highlighted the current clinical advancements of nanocarrier-based formulations for the treatment of neurodegenerative disorders, ongoing clinical studies, and challenges in clinical translation.
作者: exceed    時(shí)間: 2025-3-27 00:46
l models involved in brain research.Discusses nanoparticulat.This book presents nanoparticles as potential drug delivery carriers for overcoming the blood-brain barrier. The initial chapter of the book discusses complex brain disorders, the currently available therapies, and their limitations. The b
作者: 長(zhǎng)矛    時(shí)間: 2025-3-27 01:34
Introduction to Complex Brain Disorders, Currently Available Therapies, and Their Limitations,ty to think, feel, or behave appropriately, as well as in their social well-being. Major etiological factors which contribute to the development of complex brain disorders are genetic predispositions, environmental influences, and neurobiological abnormalities. Generally, the complex brain disorder
作者: ethereal    時(shí)間: 2025-3-27 06:25

作者: Pudendal-Nerve    時(shí)間: 2025-3-27 12:05
Introduction to Nanoparticles as a Potential Carrier for Brain Targeting,erous obstacles to the effective delivery of drugs (DD). The pivotal role of the blood-brain barrier (BBB) in targeting drugs to the brain cannot be overemphasized. Researchers have been captivated by the development of nanoparticle-based brain targeting in recent years, focusing on the design of na
作者: exorbitant    時(shí)間: 2025-3-27 14:25

作者: MIME    時(shí)間: 2025-3-27 20:57
Recent Advancements in Lipid Nanocarriers for Brain Delivery of Bioactives,se, epilepsy, Huntington’s disease, amyotrophic lateral sclerosis, multiple sclerosis, brain stroke, injury, and trauma affect millions worldwide and are very challenging to treat. The common mechanism in all these neurodegenerative disorders is the generation of oxidative stress due to an imbalance
作者: 阻礙    時(shí)間: 2025-3-28 00:26
Liposomes as a Potential Carrier for Brain Delivery,harmacodynamic and pharmacokinetic profile of concerned drugs. In this view, the nanotechnology can play a significant role to overcome the stated problem. Recently, nanoparticles are dragging lots of interest as nanodelivery system carries the drug into the brain because it provide stability for dr
作者: 圓錐    時(shí)間: 2025-3-28 02:15
Inorganic Nanoparticles for Brain Targeting Scope and Limitations,ovel nanomaterials such as inorganic nanoparticles for delivery of drug to the brain by overcoming such barriers has been explored widely in recent years. These include carbon, silver, gold, and iron oxide nanoparticles for precise delivery of drug to the brain. The various strategies include combin
作者: chastise    時(shí)間: 2025-3-28 08:18

作者: NOVA    時(shí)間: 2025-3-28 11:46

作者: 偏離    時(shí)間: 2025-3-28 15:49

作者: vocation    時(shí)間: 2025-3-28 22:18
In Vitro Cell Line Culture for Brain Research and Its Limitations,cell line models for brain research. These models encompass a wide array of neuronal and glial cell lines, primary cultures, and sophisticated systems that closely mimic the brain’s intricate microenvironments. They have become invaluable tools for investigating various facets of brain biology and p
作者: dearth    時(shí)間: 2025-3-29 00:22

作者: 向外才掩飾    時(shí)間: 2025-3-29 06:57
Safety, Stability Concerns, and Regulatory Aspects of Nanocarriers for Brain Delivery,he nanocarriers derived from metals, polymers, and other materials have shown their therapeutic efficacy against several neurological disorders during in vitro and preclinical studies. However, these nanocarriers, especially metal and silica NPs, have shown their toxicity against neuronal cell lines
作者: 譏諷    時(shí)間: 2025-3-29 10:42
Current Clinical Advancements of Nanocarriers for Brain Targeting and Limitations in Clinical Trans drug targeting, minimized side effects, improved drug efficiency, and patient compliance, nanocarriers take upper hand. Successful translation of research hypothesis led to clinical availability of a good number of nanomedicines intended for a range of physiological conditions like kidney dysfuncti
作者: Missile    時(shí)間: 2025-3-29 14:51
Application of Nanocarriers in Brain Delivery of Therapeutics
作者: Brocas-Area    時(shí)間: 2025-3-29 17:04
Application of Nanocarriers in Brain Delivery of Therapeutics978-981-97-2859-6
作者: PTCA635    時(shí)間: 2025-3-29 23:45

作者: ostensible    時(shí)間: 2025-3-30 00:11

作者: Infect    時(shí)間: 2025-3-30 07:21
https://doi.org/10.1007/978-94-015-8175-2n disorders. However, bioactives have low bioavailability, poor solubility, and inefficient delivery because of blood-central nervous system barriers. To overcome these issues, a lipid nanocarrier system was found to be a suitable strategy for delivering these bioactives. This chapter discusses lipo
作者: 微生物    時(shí)間: 2025-3-30 08:13

作者: Pulmonary-Veins    時(shí)間: 2025-3-30 13:47
T. S. Kumar,A. Josephine,G. Dharaniin the drug delivery to the brain. The biosafety and toxicity aspect of these nanomaterials will also be discussed. Furthermore, the most recent advancements in the field of novel strategies to overcome the challenges associated with drug delivery to the brain have been discussed.
作者: 態(tài)度暖昧    時(shí)間: 2025-3-30 19:10

作者: 并入    時(shí)間: 2025-3-30 21:51

作者: 到婚嫁年齡    時(shí)間: 2025-3-31 03:03
Bahar Aslanbay Guler,Esra Imamoglu’s complexities. By offering insights into the ever-evolving landscape of in vitro cell line culture in brain research, this review aims to underscore their critical role in shaping the future of neuroscience and its potential to address pressing questions related to neurological disorders and brain
作者: 使更活躍    時(shí)間: 2025-3-31 08:45
https://doi.org/10.1007/978-981-99-2901-6gs from animal studies to clinical applications. Additionally, the limited ability to mimic the intricate neural networks and cognitive functions of the human brain remains a major obstacle. This abstract also delves into the ethical considerations surrounding the use of in vivo animal models, empha
作者: infatuation    時(shí)間: 2025-3-31 12:19
Introduction to Nanoparticles as a Potential Carrier for Brain Targeting,brain delivery presents numerous benefits compared to traditional DDS, despite facing significant obstacles. It boasts rapidity, patient-friendliness, and noninvasiveness; bypasses first-pass metabolism; and provides swift action. The major hindrances to utilizing NPs for DD purposes are the instabi
作者: flamboyant    時(shí)間: 2025-3-31 16:38

作者: 連詞    時(shí)間: 2025-3-31 19:47
Recent Advancements in Lipid Nanocarriers for Brain Delivery of Bioactives,n disorders. However, bioactives have low bioavailability, poor solubility, and inefficient delivery because of blood-central nervous system barriers. To overcome these issues, a lipid nanocarrier system was found to be a suitable strategy for delivering these bioactives. This chapter discusses lipo




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