標題: Titlebook: Antiviral Innate Immunity; Chunfu Zheng Book 2025 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Sci [打印本頁] 作者: 偏差 時間: 2025-3-21 18:25
書目名稱Antiviral Innate Immunity影響因子(影響力)
書目名稱Antiviral Innate Immunity影響因子(影響力)學科排名
書目名稱Antiviral Innate Immunity網(wǎng)絡公開度
書目名稱Antiviral Innate Immunity網(wǎng)絡公開度學科排名
書目名稱Antiviral Innate Immunity被引頻次
書目名稱Antiviral Innate Immunity被引頻次學科排名
書目名稱Antiviral Innate Immunity年度引用
書目名稱Antiviral Innate Immunity年度引用學科排名
書目名稱Antiviral Innate Immunity讀者反饋
書目名稱Antiviral Innate Immunity讀者反饋學科排名
作者: Discrete 時間: 2025-3-22 00:12
Luciferase Reporter Systems in Investigating Interferon Antiviral Innate Immunity,ase complementary reporter method, which was designed to explore protein-protein interactions associated with antiviral immunity. These methodologies offer invaluable knowledge regarding the molecular mechanisms underlying antiviral immune pathways and have the potential to support the development o作者: 閑蕩 時間: 2025-3-22 00:29
Book 2025tep and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls...?..Authoritative and practical, .Antiviral Innate Immunity. serves as an ideal guide for researchers working in this vital area of the virology and innate immunity fields..作者: 喪失 時間: 2025-3-22 08:19 作者: CORE 時間: 2025-3-22 11:21 作者: 人工制品 時間: 2025-3-22 16:06
1064-3745 Antiviral Innate Immunity. serves as an ideal guide for researchers working in this vital area of the virology and innate immunity fields..978-1-0716-4110-1978-1-0716-4108-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: narcotic 時間: 2025-3-22 17:23 作者: 收藏品 時間: 2025-3-23 00:40
Forced Commutated HVDC Converters,infectious diseases based on innate immunotherapy. In this section, we use the E3 ubiquitin ligase as an example to guide the identification of a protein belonging to the RING Finger (RNF) family that regulates the RIG-I-mediated IFN-I pathway through ubiquitination.作者: 搜集 時間: 2025-3-23 04:19
Lia Bijkerk,Wilma van der Heideibit altered responses to infection. This integrated approach provides researchers in immunology and virology with a resource and a robust framework for uncovering the genetic basis of host-pathogen interactions and the arsenal of the innate immune system against viral invasions.作者: 不開心 時間: 2025-3-23 06:39 作者: AFFIX 時間: 2025-3-23 11:18
Lia Bijkerk,Wilma van der Heidegen infections, particularly RNA virus infections. In this chapter, we will introduce a “pull-down” method for identifying RIG-I-like receptors, related RNA helicases, Toll-like receptors, and other RNA sensors.作者: Promotion 時間: 2025-3-23 14:46 作者: 旅行路線 時間: 2025-3-23 21:48
https://doi.org/10.1007/978-90-313-7808-1 methods of protein lysine acetylation determination in virus-infected macrophages and embryonic fibroblast cells or proteins-overexpressed HEK 293?T cells in the context of antiviral innate immunity.作者: 無王時期, 時間: 2025-3-23 22:36
A Guideline Strategy for Identifying Genes/Proteins Regulating Antiviral Innate Immunity,infectious diseases based on innate immunotherapy. In this section, we use the E3 ubiquitin ligase as an example to guide the identification of a protein belonging to the RING Finger (RNF) family that regulates the RIG-I-mediated IFN-I pathway through ubiquitination.作者: 傳染 時間: 2025-3-24 05:18
CRISPR-Mediated Library Screening of Gene-Knockout Cell Lines for Investigating Antiviral Innate Imibit altered responses to infection. This integrated approach provides researchers in immunology and virology with a resource and a robust framework for uncovering the genetic basis of host-pathogen interactions and the arsenal of the innate immune system against viral invasions.作者: annexation 時間: 2025-3-24 06:51
CRISPR-Mediated Construction of Gene-Knockout Mice for Investigating Antiviral Innate Immunity,l, researchers can efficiently generate specific gene knockout mouse models, which not only helps in understanding the functions of the immune system but also offers a powerful experimental tool for exploring the mechanisms of antiviral innate immunity.作者: 離開可分裂 時間: 2025-3-24 14:23
Identifying RNA Sensors in Antiviral Innate Immunity,gen infections, particularly RNA virus infections. In this chapter, we will introduce a “pull-down” method for identifying RIG-I-like receptors, related RNA helicases, Toll-like receptors, and other RNA sensors.作者: Plaque 時間: 2025-3-24 16:09 作者: 談判 時間: 2025-3-24 19:20 作者: 斜谷 時間: 2025-3-25 00:46 作者: VICT 時間: 2025-3-25 03:30
3 Beslissen op basis van leerstijlenTMs) caused by changes in cell metabolism during viral infection. This chapter considers the palmitoylation, carbonylation, and alkylation of STING and presents detailed information and experimental procedures for measuring PTMs using click chemistry.作者: Radiculopathy 時間: 2025-3-25 09:26
Subsequences of the Haar system,sents detailed information and experimental procedures of Cryo-EM for determining the structures of the complexes using STING as an example. The procedures included a sample quality check, high-resolution data acquisition, and image processing for Cryo-EM 3D structure determination.作者: PIZZA 時間: 2025-3-25 15:40
Hypertrichosen und Hirsutismus,evious studies. An observational case- or cohort-based study of antiviral innate immunity may support this theoretical hypothesis but is not appropriate for clinical practice or treatment. RCTs are the gold standard for epidemiological studies and occupy a greater role in the hierarchy of evidence.作者: Friction 時間: 2025-3-25 16:47
1064-3745 experts.This detailed volume explores a variety of techniques for studying antiviral innate immunity and the type I interferon (IFN-I) signaling pathway. Beginning with guidelines to identify novel proteins from the host or viruses that regulate the antiviral IFN-I signaling pathway, the book conti作者: inflame 時間: 2025-3-25 20:16
https://doi.org/10.1007/b117759s to replication in various ways. Viral genes/proteins play a key role in evading antiviral innate immunity. Here, we will discuss the interference of viruses with antiviral innate immunity and the strategy for identifying viral gene/protein immune evasion.作者: 使腐爛 時間: 2025-3-26 02:01 作者: 漂泊 時間: 2025-3-26 07:16
5 Beslissen op basis van kernkwaliteitenn recent years has provided an enormous scope for research in this field. This chapter describes the application, significance, and experimental procedures of a variety of transcriptomic technologies in antiviral natural immunity.作者: 課程 時間: 2025-3-26 10:22
Haar Series and Linear Operatorscritical role in innate immunity by sensing bacterial or viral nucleic acids and are preferentially transported to the phagosomal membrane of innate immune cells upon activation. Therefore, phagosome isolation is helpful for studies on pathogenic invasion and the functions of phagosome proteins, including endosomal TLRs.作者: GRIPE 時間: 2025-3-26 13:00
A Guideline Strategy for Identifying a Viral Gene/Protein Evading Antiviral Innate Immunity,s to replication in various ways. Viral genes/proteins play a key role in evading antiviral innate immunity. Here, we will discuss the interference of viruses with antiviral innate immunity and the strategy for identifying viral gene/protein immune evasion.作者: HAIRY 時間: 2025-3-26 18:30 作者: Affiliation 時間: 2025-3-26 20:58 作者: RENAL 時間: 2025-3-27 04:46
Phagosome Isolation with Magnetic Beads and Purification of Toll-Like Receptor (TLR) Complexes in Pcritical role in innate immunity by sensing bacterial or viral nucleic acids and are preferentially transported to the phagosomal membrane of innate immune cells upon activation. Therefore, phagosome isolation is helpful for studies on pathogenic invasion and the functions of phagosome proteins, including endosomal TLRs.作者: Esophagitis 時間: 2025-3-27 06:54
Phase 2: ADP (Analyze/Design/Plan),ve genetic variations in organisms. It is now widely used in the study of viral immune evasion mechanisms. This chapter will introduce the use of the CRISPR-Cas9 system for editing herpes simplex virus 1 (HSV-1) genes to explore the mechanisms by which HSV-1 evades host innate immunity and the experimental procedures involved.作者: 大喘氣 時間: 2025-3-27 11:43 作者: 修飾 時間: 2025-3-27 14:00
CRISPR-Mediated Viral Gene Knockout to Investigate Viral Evasion of Antiviral Innate Immunity,ve genetic variations in organisms. It is now widely used in the study of viral immune evasion mechanisms. This chapter will introduce the use of the CRISPR-Cas9 system for editing herpes simplex virus 1 (HSV-1) genes to explore the mechanisms by which HSV-1 evades host innate immunity and the experimental procedures involved.作者: FRONT 時間: 2025-3-27 18:45 作者: 令人心醉 時間: 2025-3-27 22:01
Luciferase Reporter Assay for Determining the Signaling Activity of Interferons,is chapter presents detailed information and experimental procedures for measuring interferon (IFN)-induced Interferon-Stimulated Response Element (ISRE) promoter activity using the dual luciferase reporter assay.作者: 無法破譯 時間: 2025-3-28 05:26 作者: 貧困 時間: 2025-3-28 07:28 作者: nitric-oxide 時間: 2025-3-28 14:26 作者: 雄辯 時間: 2025-3-28 15:45 作者: 占卜者 時間: 2025-3-28 21:53
A Guideline Strategy for Identifying a Viral Gene/Protein Evading Antiviral Innate Immunity,is, endoplasmic reticulum (ER) stress, and autophagy are involved in antiviral innate immunity. Viruses abrogate the antiviral immune response of cells to replication in various ways. Viral genes/proteins play a key role in evading antiviral innate immunity. Here, we will discuss the interference of作者: Exhilarate 時間: 2025-3-28 23:22
Luciferase Reporter Assay for Determining the Signaling Activity of Interferons,nduced by certain signal pathways in the cells. In particular, the sensitive characteristics of luciferase highlight its significance in many experiments, such as weak promoter analysis, transfection studies using small amounts of DNA, and detection in cell lines with low transfection efficiency. Th作者: Stress-Fracture 時間: 2025-3-29 06:46 作者: 不能妥協(xié) 時間: 2025-3-29 09:24
Identifying a Ubiquitinated Adaptor Protein by a Viral E3 Ligase Through Co-immunoprecipitation,d be identified by combining co-immunoprecipitation with SDS-PAGE followed by immunoblotting. In this chapter, we use Herpes Simplex Virus 1 immediate-early protein ICP0-mediated polyubiquitination of p50 as an example to describe the method to identify a ubiquitinated adaptor protein by a viral E3 作者: 指數(shù) 時間: 2025-3-29 12:54
CRISPR-Mediated Viral Gene Knockout to Investigate Viral Evasion of Antiviral Innate Immunity,es have evolved multiple strategies to evade the host immune system through coevolution with hosts. The CRISPR-Cas system is an adaptive immune system in bacteria or archaea that defends against viral reinvasion by targeting nucleic acids for cleavage. Based on the characteristics of Cas proteins an作者: Armory 時間: 2025-3-29 16:09
CRISPR-Mediated Library Screening of Gene-Knockout Cell Lines for Investigating Antiviral Innate Imactions. This protocol describes the use of CRISPR-mediated library screening to identify key functional genes regulating the innate immune response to PEDV infection. We detail a step-by-step process, starting from the design and construction of a customized CRISPR knockout library targeting genes 作者: nugatory 時間: 2025-3-29 23:35 作者: 大吃大喝 時間: 2025-3-30 00:25
Click Chemistry in Detecting Protein Modification, specific small molecular groups at the molecular level. Click chemistry offers several advantages, including high efficiency, good selectivity, mild conditions, and few side reactions. These features make it a valuable tool for in-depth analysis of various protein posttranslational modifications (P作者: CLAN 時間: 2025-3-30 06:32
Transcriptomics in the Study of Antiviral Innate Immunity, transcriptomic technologies include microarrays and RNA sequencing, and the rapid development of single-cell sequencing and spatial transcriptomics in recent years has provided an enormous scope for research in this field. This chapter describes the application, significance, and experimental proce作者: 痛苦一生 時間: 2025-3-30 10:01 作者: amplitude 時間: 2025-3-30 12:42
Identifying RNA Sensors in Antiviral Innate Immunity,eceptors (PRRs), which detect Pathogen-Associated Molecular Patterns (PAMPs). Nucleic acids, including RNA and DNA, are recognized as particularly significant PAMPs, especially in the context of viral pathogens. During RNA virus infections, specific sequences in the viral RNA mark it as non-self, en作者: 相信 時間: 2025-3-30 19:18
DNA PAMPs as Molecular Tools for the cGAS-STING Signaling Pathways,ptors (PRRs) and their homologs, pathogen-associated molecular patterns (PAMPs), form the foundation for driving innate immune activation and the induction of immune responses during infection. In the context of DNA viruses or bacterial infections, specific DNA sequences are recognized and bound by 作者: miracle 時間: 2025-3-31 00:38 作者: 不能妥協(xié) 時間: 2025-3-31 02:06 作者: 真實的人 時間: 2025-3-31 08:37
In Vitro Cleavage Assay to Characterize DENV NS2B3 Antagonism of cGAS,ted by dsDNA from viral and bacterial origins as well as dsDNA leaked from damaged mitochondria and nucleus. Eventually, cGAS activation launches the cell into an antiviral state to restrict the replication of both DNA and RNA viruses. Throughout the long co-evolution, viruses devise many strategies作者: Subdue 時間: 2025-3-31 12:15 作者: FLIRT 時間: 2025-3-31 13:54
Cryo-Electron Microscopy in the Study of Antiviral Innate Immunity,lenging samples, which are not readily available for traditional techniques. In particular, the strength of super macro-complexes and the lack of a need for crystals for cryo-EM make this technique feasible for the structural study of complexes involved in antiviral innate immunity. This chapter pre作者: Calculus 時間: 2025-3-31 18:01 作者: 一回合 時間: 2025-3-31 23:30
https://doi.org/10.1007/978-1-0716-4108-8Type I interferon (IFN-I) signaling pathway; Viral infections; Novel regulatory factors; CRISPR-mediate作者: 種屬關(guān)系 時間: 2025-4-1 01:52 作者: 有法律效應 時間: 2025-4-1 07:10
Chunfu ZhengIncludes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts作者: Obverse 時間: 2025-4-1 11:27 作者: 離開 時間: 2025-4-1 17:46 作者: FLAIL 時間: 2025-4-1 19:54
https://doi.org/10.1007/978-3-662-66968-6d be identified by combining co-immunoprecipitation with SDS-PAGE followed by immunoblotting. In this chapter, we use Herpes Simplex Virus 1 immediate-early protein ICP0-mediated polyubiquitination of p50 as an example to describe the method to identify a ubiquitinated adaptor protein by a viral E3 ligase by co-immunoprecipitation.作者: Migratory 時間: 2025-4-2 00:03
Forced Commutated HVDC Converters,ISGs) and is finely regulated by numerous positive and negative factors at different signaling adaptors. During this process, posttranslational modifications, especially ubiquitination, are the most common regulatory strategy used by the host to switch the antiviral innate signaling pathway and are 作者: 冥界三河 時間: 2025-4-2 03:23
https://doi.org/10.1007/b117759is, endoplasmic reticulum (ER) stress, and autophagy are involved in antiviral innate immunity. Viruses abrogate the antiviral immune response of cells to replication in various ways. Viral genes/proteins play a key role in evading antiviral innate immunity. Here, we will discuss the interference of作者: 引水渠 時間: 2025-4-2 07:42
https://doi.org/10.1007/978-3-658-36603-2nduced by certain signal pathways in the cells. In particular, the sensitive characteristics of luciferase highlight its significance in many experiments, such as weak promoter analysis, transfection studies using small amounts of DNA, and detection in cell lines with low transfection efficiency. Th作者: 行業(yè) 時間: 2025-4-2 14:22
