標(biāo)題: Titlebook: Antibiotic Resistance Protocols; Stephen H. Gillespie Book 2024Latest edition The Editor(s) (if applicable) and The Author(s), under exclu [打印本頁(yè)] 作者: Grievous 時(shí)間: 2025-3-21 17:59
書目名稱Antibiotic Resistance Protocols影響因子(影響力)
作者: Rejuvenate 時(shí)間: 2025-3-21 22:11
Three-Dimensional Rotary Culture to Model Mycobacterial Biofilms in Low-Shear Detergent-Free Liquidbility of a wide range of bacterial pathogens. Rotary cell culture systems create three-dimensional cellular structures, primarily applied to eukaryotic organoids, that better capture characteristics of the cells in vivo. Here, we describe how to apply a low-shear, detergent-free rotary cell culture作者: essential-fats 時(shí)間: 2025-3-22 02:10 作者: 裁決 時(shí)間: 2025-3-22 05:13
Modified HT-SPOTi: An Antimicrobial Susceptibility Testing to Evaluate Formulated Therapeutic Combi, researchers from all around the world have generated a selection of various formulated (viz. nanoparticulate, liposomal) therapeutic combinations to be evaluated for new antimicrobial drug discovery. To meet the urgent need for accelerating new antibacterial drug development, we need rapid but rel作者: fertilizer 時(shí)間: 2025-3-22 09:28
Investigating Combination Therapy as a Means to Enhance Activity and Repurpose Antimicrobials,, this is becoming less and less true with drug-resistant, multi-drug-resistant, extensively drug-resistant, and untreatable infections becoming more common. Where single-drug therapy (monotherapy) fails, we will turn to multi-drug therapy. Alternatively, combination therapy could be useful to preve作者: Vaginismus 時(shí)間: 2025-3-22 14:56 作者: Exclaim 時(shí)間: 2025-3-22 18:02
Using Hollow Fiber to Model Treatment of Antimicrobial-Resistant Organisms,DA for human-like studies is the hollow fiber bioreactor (HFS). HFSs are highly controllable, self-contained systems that allow for the modeling of individual tissues and disease phenotypes. Oxygen, drug concentration & half-life, and immune cell invasion are all scalable to human and veterinary con作者: arsenal 時(shí)間: 2025-3-22 21:13 作者: RADE 時(shí)間: 2025-3-23 04:55
Within-Host Mathematical Models of Antibiotic Resistance,modeling which provides an understanding of how pathogens—bacteria, fungi, parasites, or viruses—develop, spread, and evolve inside a single individual and their interaction with the host’s immune system..Such models have the potential to provide a more detailed and complete description of the patho作者: COMA 時(shí)間: 2025-3-23 06:13 作者: Mucosa 時(shí)間: 2025-3-23 11:02 作者: isotope 時(shí)間: 2025-3-23 15:59
Phylogenetic Survival Analysis, of interest over evolutionary time. Knowledge of this kind may allow for the emergence of key traits to be predicted and pre-empted from currently circulating strains in the future. Here, we present a novel genome-wide survival analysis and use the emergence of drug resistance in . as an example to作者: visceral-fat 時(shí)間: 2025-3-23 20:25
Rapid Drug Susceptibility Testing to Preserve Antibiotics, lives every year. A major driver of resistance is the absence of susceptibility testing at the time a healthcare worker needs to prescribe an antimicrobial. The effect is that many prescriptions are unintentionally wasted and expose mutable organisms to antibiotics increasing the risk of resistance作者: acquisition 時(shí)間: 2025-3-24 01:48 作者: Intervention 時(shí)間: 2025-3-24 05:12
Improved Diagnosis and Treatment Monitoring of Tuberculosis Using Stool and the Tuberculosis Bacterreated on the basis of clinical findings and consequently some will be exposed to anti-tuberculosis drugs unnecessarily. Moreover, for those appropriately on treatment and unable to produce a sputum sample, it will be impossible to monitor the response to treatment. We have shown that stool is a pot作者: 遠(yuǎn)地點(diǎn) 時(shí)間: 2025-3-24 08:26 作者: Dorsal-Kyphosis 時(shí)間: 2025-3-24 12:19 作者: vector 時(shí)間: 2025-3-24 14:54 作者: 運(yùn)氣 時(shí)間: 2025-3-24 19:12 作者: 痛得哭了 時(shí)間: 2025-3-25 01:01
Quantifying Viable , Safely Obviating the Need for High Containment Facilities,ing sputum samples by either heat or guanidine thiocyanate (GTC) that renders them safe without affecting the quantification of viable bacteria. This method eliminates the need for level 3 containment laboratory for the tuberculosis molecular bacterial load assay (TB-MBLA) and is applicable in low- and middle-income countries.作者: 柳樹；枯黃 時(shí)間: 2025-3-25 04:49 作者: 否決 時(shí)間: 2025-3-25 08:57 作者: 材料等 時(shí)間: 2025-3-25 12:35 作者: follicle 時(shí)間: 2025-3-25 19:18
https://doi.org/10.1007/978-3-642-95369-9The TB MBLA only detects live organisms and thus, can be used to follow the response to treatment. In this chapter, we describe a protocol for TB-MBLA, an RNA-based assay, and apply it to quantify TB bacteria in stool.作者: fleeting 時(shí)間: 2025-3-25 23:44
Three-Dimensional Rotary Culture to Model Mycobacterial Biofilms in Low-Shear Detergent-Free Liquidplay antimicrobial drug tolerance, presence of an extracellular matrix, and evidence of cell wall remodeling, all features of biofilm-associated bacteria that may be relevant to the treatment of tuberculosis.作者: 后來 時(shí)間: 2025-3-26 02:02
Using Hollow Fiber to Model Treatment of Antimicrobial-Resistant Organisms,cal validity than classical in vitro techniques making minimal inhibitory concentration (MIC) data generated on the bench more translatable to the clinic..In this chapter, we will outline the background of the HFS and some typical uses.作者: 胎兒 時(shí)間: 2025-3-26 05:31 作者: 顛簸下上 時(shí)間: 2025-3-26 10:13 作者: Foolproof 時(shí)間: 2025-3-26 14:47
1064-3745 experts.This fully updated edition explores current techniques for research into antibiotic resistance. The book begins with?how samples are collected, strains isolated and sequenced, and the results integrated in the microbiological workflow.? It continues with novel methods to test resistance and作者: LATER 時(shí)間: 2025-3-26 19:00 作者: 入伍儀式 時(shí)間: 2025-3-27 00:02
https://doi.org/10.1007/978-3-642-95369-9are often customized and detailed protocols are difficult to access. Here, we provide a step-by-step workflow for the processing and interpretation of short-read sequencing data and give an overview of available analysis pipelines.作者: Nebulous 時(shí)間: 2025-3-27 01:59
Phylogenetic Survival Analysis,rculating strains in the future. Here, we present a novel genome-wide survival analysis and use the emergence of drug resistance in . as an example to demonstrate the potential and utility of the technique.作者: carotenoids 時(shí)間: 2025-3-27 07:15
Use of Whole Genome Sequencing for , Complex Antimicrobial Susceptibility Testing: From Sequence Daare often customized and detailed protocols are difficult to access. Here, we provide a step-by-step workflow for the processing and interpretation of short-read sequencing data and give an overview of available analysis pipelines.作者: 小爭(zhēng)吵 時(shí)間: 2025-3-27 10:03 作者: 停止償付 時(shí)間: 2025-3-27 14:13 作者: expire 時(shí)間: 2025-3-27 18:06
https://doi.org/10.1007/978-3-642-95369-9evolutionize the investigation and management of outbreaks replacing conventional genotyping and other discrimination systems. Here, we outline specific procedures and protocols to implement WGS into investigation of outbreaks in healthcare settings.作者: motor-unit 時(shí)間: 2025-3-28 01:57
https://doi.org/10.1007/978-3-642-95369-9ch laboratory to implement WGS technology effectively. Here, we provide a detailed workflow for a DNA-library preparation based on an adapted Illumina protocol optimized for the reduction of reagent costs.作者: 設(shè)想 時(shí)間: 2025-3-28 04:54
Investigating Photoactive Antimicrobials as Alternatives (or Adjuncts) to Traditional Therapy,ng oxidative stress when compared with human cells therefore a degree of selective toxicity can be achieved with aPDT..In this chapter, we outline methodologies for testing aPDT in vitro using standard lab equipment.作者: VAN 時(shí)間: 2025-3-28 08:21
Application of Pathogen Genomics to Outbreak Investigation,evolutionize the investigation and management of outbreaks replacing conventional genotyping and other discrimination systems. Here, we outline specific procedures and protocols to implement WGS into investigation of outbreaks in healthcare settings.作者: Negligible 時(shí)間: 2025-3-28 11:10
Use of Whole Genome Sequencing for , Complex Antimicrobial Susceptibility Testing,ch laboratory to implement WGS technology effectively. Here, we provide a detailed workflow for a DNA-library preparation based on an adapted Illumina protocol optimized for the reduction of reagent costs.作者: 有組織 時(shí)間: 2025-3-28 18:13 作者: Benign 時(shí)間: 2025-3-28 22:26 作者: CULP 時(shí)間: 2025-3-29 01:05 作者: 騷動(dòng) 時(shí)間: 2025-3-29 06:35 作者: bifurcate 時(shí)間: 2025-3-29 08:55 作者: abstemious 時(shí)間: 2025-3-29 11:40
Fragensammlung zur Selbstkontrollebility of a wide range of bacterial pathogens. Rotary cell culture systems create three-dimensional cellular structures, primarily applied to eukaryotic organoids, that better capture characteristics of the cells in vivo. Here, we describe how to apply a low-shear, detergent-free rotary cell culture作者: DOSE 時(shí)間: 2025-3-29 17:08 作者: 嗎啡 時(shí)間: 2025-3-29 19:58
Fragensammlung zur Selbstkontrolle, researchers from all around the world have generated a selection of various formulated (viz. nanoparticulate, liposomal) therapeutic combinations to be evaluated for new antimicrobial drug discovery. To meet the urgent need for accelerating new antibacterial drug development, we need rapid but rel作者: Ataxia 時(shí)間: 2025-3-30 01:17 作者: 商店街 時(shí)間: 2025-3-30 05:51 作者: collagen 時(shí)間: 2025-3-30 08:34
https://doi.org/10.1007/978-3-642-78791-1DA for human-like studies is the hollow fiber bioreactor (HFS). HFSs are highly controllable, self-contained systems that allow for the modeling of individual tissues and disease phenotypes. Oxygen, drug concentration & half-life, and immune cell invasion are all scalable to human and veterinary con作者: 結(jié)合 時(shí)間: 2025-3-30 13:51 作者: 一條卷發(fā) 時(shí)間: 2025-3-30 19:44
https://doi.org/10.1007/978-3-642-79615-9modeling which provides an understanding of how pathogens—bacteria, fungi, parasites, or viruses—develop, spread, and evolve inside a single individual and their interaction with the host’s immune system..Such models have the potential to provide a more detailed and complete description of the patho作者: 殺蟲劑 時(shí)間: 2025-3-31 00:15
Schutzimpfungen bei Viruserkrankungen heuteh an adequate representation of the elements. IBMs simulate the actions and interaction of discrete . within a system in order to discover the pattern of behavior that comes from these interactions. Examples of individuals/agents in biological systems are individual immune cells and bacteria that ac作者: pus840 時(shí)間: 2025-3-31 04:44 作者: exhibit 時(shí)間: 2025-3-31 08:36 作者: 即席演說 時(shí)間: 2025-3-31 12:37
Funktionsdiagnostik der Nasenatmung lives every year. A major driver of resistance is the absence of susceptibility testing at the time a healthcare worker needs to prescribe an antimicrobial. The effect is that many prescriptions are unintentionally wasted and expose mutable organisms to antibiotics increasing the risk of resistance作者: SAGE 時(shí)間: 2025-3-31 14:50 作者: 小畫像 時(shí)間: 2025-3-31 17:37
https://doi.org/10.1007/978-3-642-95369-9reated on the basis of clinical findings and consequently some will be exposed to anti-tuberculosis drugs unnecessarily. Moreover, for those appropriately on treatment and unable to produce a sputum sample, it will be impossible to monitor the response to treatment. We have shown that stool is a pot作者: Conscientious 時(shí)間: 2025-3-31 23:17 作者: Ballerina 時(shí)間: 2025-4-1 04:59 作者: gnarled 時(shí)間: 2025-4-1 09:49
https://doi.org/10.1007/978-3-642-95369-9and second-line anti-tuberculosis drugs. However, bioinformatic pipelines and mutation catalogs to predict antimicrobial resistances in MTBC isolates are often customized and detailed protocols are difficult to access. Here, we provide a step-by-step workflow for the processing and interpretation of作者: Infinitesimal 時(shí)間: 2025-4-1 13:43
https://doi.org/10.1007/978-3-642-95369-9es. The detection of antimicrobial-resistant (AMR) determinants using genomic methods can provide valuable information on the emergence of resistance. Here we describe an approach to detecting AMR determinants using an open access and freely available platform which does not require bioinformatic ex作者: Root494 時(shí)間: 2025-4-1 15:33 作者: giggle 時(shí)間: 2025-4-1 20:08
Fragensammlung zur Selbstkontrollethogen that has developed resistance to a range of antibiotics. The zebrafish larval model of systemic disease has been increasingly utilized to elucidate . virulence mechanisms and host-pathogen interactions. Here, we outline how this model can be used to investigate the effects of different antibiotics alone and in combination against ..
