標(biāo)題: Titlebook: Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases; Namita Agrawal Book 2024 The Editor(s) (if applica [打印本頁] 作者: 要旨 時(shí)間: 2025-3-21 18:40
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書目名稱Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases讀者反饋學(xué)科排名
作者: 平項(xiàng)山 時(shí)間: 2025-3-21 20:34
Mechanism Underlying Major Neurodegenerative Disorders,e to uncover the underlying molecular and cellular pathogenic mechanisms. Even though NDDs uniquely affect specific neuronal subpopulations, the accumulation of distinct protein is known to cause neuronal loss. Additionally, with the advent of new techniques, progressive neuronal loss, synaptic dysf作者: 膽小鬼 時(shí)間: 2025-3-22 02:39
Involvement of Metabolic Paradigm in Progression of Neurodegenerative Diseases,vastating neurological disorders. Despite of the significant increase in number of patients all over the world, these diseases are characterized by the lack of true disease-modifying therapy that can reverse or halt disease progression. Recent studies indicated that metabolic alterations have been o作者: interrogate 時(shí)間: 2025-3-22 07:25 作者: 撤退 時(shí)間: 2025-3-22 08:58
Altered Glucose Homeostasis in Neurological Disorders,s and it has been observed in several neurodegenerative disorders (NDDs). A major focus in the field of neurodegeneration is about understanding the mechanisms underlying glucose metabolism, and the regulation of the process during disease onset and progression relieves the neurons from degenerative作者: TRAWL 時(shí)間: 2025-3-22 13:43
Lipid Metabolism: Key Determinant in Neurodegenerative Diseases,nced by dietary lipids. Lipids play a pivotal role in normal and physiological function of the brain. There are eight different classes of lipids that form the central nervous system. To understand the link between lipids and neurodegenerative diseases, the role of these different classes of lipids 作者: predict 時(shí)間: 2025-3-22 20:01
Dysregulated Peripheral Metabolism in Neurodegenerative Disorders,evastating neurological disorders. Several reported evidences suggest existence of a strong link between metabolic syndrome and neurodegeneration. One common pathophysiological change observed in neurodegenerative diseases is a change in the metabolic function of nervous system and peripheral cells.作者: arrhythmic 時(shí)間: 2025-3-22 21:16
Protein Metabolism: Critical Factors Implicated in Neurodegenerative Diseases,quitin-proteasome system and autophagy to degrade misfolded protein. All these processes are precisely regulated to maintain proper proteostasis and homeostasis. Alteration in these processes such as anomalous posttranslational modifications, misfolding, and aberrant protein quality control system r作者: PACK 時(shí)間: 2025-3-23 03:46 作者: AMPLE 時(shí)間: 2025-3-23 08:28
Unveiling RNA Dysfunction: A Key Player in Neurodegeneration,tes various aspects of the cellular function. In the past few decades, RNA metabolism has gained attention in the context of neurodegenerative diseases, since the underlying cause of a number of disorders is disturbed RNA processing. Alteration in RNA metabolism affects not only the proteins that ar作者: 有權(quán) 時(shí)間: 2025-3-23 13:03
Emerging Relationship Between the Gut Microbiota and Neurodegenerative Disorders, termed as gut microbiota and have been known to affect the function as well as the behavioral aspects of human health. Recent research shows that the microorganisms in our gut play a crucial role in determining our health and susceptibility to disease. Newly identified intricacies of connection bet作者: 馬具 時(shí)間: 2025-3-23 14:11
Signaling Pathways in Neurodegeneration,ing dementia. Neurodegenerative diseases are usually characterized by the accumulation of misfolded proteins in the neuronal cells and malfunction of proteasomal, lysosomal, autophagosomal, or mitochondrial systems that ultimately lead to neurodegeneration. Emerging evidence suggests that dysregulat作者: 誘騙 時(shí)間: 2025-3-23 20:45 作者: 占線 時(shí)間: 2025-3-24 00:43 作者: Cursory 時(shí)間: 2025-3-24 05:18
Phytochemicals: Promising Alternatives for Metabolic Regulation in Neurodegenerative Diseases,). Despite the significant efforts and understanding of the major pathways involved in the NDDs, there is no cure of these debilitating diseases. Presently, for the treatment of NDDs, some conventional drugs are available, but they are very expensive and in addition exhibit side effects. Since plant作者: Pander 時(shí)間: 2025-3-24 07:00 作者: 600 時(shí)間: 2025-3-24 13:09
978-981-97-4290-5The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor作者: Ointment 時(shí)間: 2025-3-24 15:51
Namita AgrawalProvides a detailed perspective of metabolic changes associated with different types of neurodegenerative diseases (NDD).Explains significant involvements of metabolic alteration in NDD prognosis, pat作者: 保守 時(shí)間: 2025-3-24 22:39 作者: diskitis 時(shí)間: 2025-3-25 01:17 作者: 從屬 時(shí)間: 2025-3-25 03:22 作者: frugal 時(shí)間: 2025-3-25 10:11 作者: 赦免 時(shí)間: 2025-3-25 15:31
Cytostatische Substanzen und ihre Wirkungse, synaptic plasticity, and neurogenesis. Astrocytes feed and nourish neurons with metabolites and growth factors. Oligodendrocytes also provide metabolic support and neurotrophic factors and produce myelin. Further, metabolic changes in glial cells have been reported in neurodegenerative diseases.作者: Antimicrobial 時(shí)間: 2025-3-25 17:37 作者: 彎曲道理 時(shí)間: 2025-3-25 21:21
Grundlagen und Technologien des Ottomotorsnced by dietary lipids. Lipids play a pivotal role in normal and physiological function of the brain. There are eight different classes of lipids that form the central nervous system. To understand the link between lipids and neurodegenerative diseases, the role of these different classes of lipids 作者: OMIT 時(shí)間: 2025-3-26 02:04
Grundlagen und Technologien des Ottomotorsevastating neurological disorders. Several reported evidences suggest existence of a strong link between metabolic syndrome and neurodegeneration. One common pathophysiological change observed in neurodegenerative diseases is a change in the metabolic function of nervous system and peripheral cells.作者: 顯而易見 時(shí)間: 2025-3-26 04:31 作者: FLAT 時(shí)間: 2025-3-26 08:29
Grundlagen und Technologien des Ottomotorsce of correct transcriptomic and genetic signature across different cell types. RNA-binding proteins (RBPs) interact with RNA to maintain RNA metabolism. Therefore, disruption of this RNA metabolism is linked to dysregulation of cellular processes involved in disease pathogenesis. Neurodegenerative 作者: Pelvic-Floor 時(shí)間: 2025-3-26 14:41
Grundlagen und Technologien des Ottomotorstes various aspects of the cellular function. In the past few decades, RNA metabolism has gained attention in the context of neurodegenerative diseases, since the underlying cause of a number of disorders is disturbed RNA processing. Alteration in RNA metabolism affects not only the proteins that ar作者: 斜坡 時(shí)間: 2025-3-26 17:32
Grundlagen und Technologien des Ottomotors termed as gut microbiota and have been known to affect the function as well as the behavioral aspects of human health. Recent research shows that the microorganisms in our gut play a crucial role in determining our health and susceptibility to disease. Newly identified intricacies of connection bet作者: Oafishness 時(shí)間: 2025-3-26 23:12
Historie und Rahmenbedingungen,ing dementia. Neurodegenerative diseases are usually characterized by the accumulation of misfolded proteins in the neuronal cells and malfunction of proteasomal, lysosomal, autophagosomal, or mitochondrial systems that ultimately lead to neurodegeneration. Emerging evidence suggests that dysregulat作者: Keratectomy 時(shí)間: 2025-3-27 01:40
https://doi.org/10.1007/978-3-211-47104-3 people worldwide. Till date, despite significant understanding about the mechanisms involved in the disease, none of the treatment regimens have been proved to prevent or suppress it..Neuroimaging has revolutionized the understanding of brain function and its abnormality and has become an essential作者: 打谷工具 時(shí)間: 2025-3-27 08:08 作者: 撕裂皮肉 時(shí)間: 2025-3-27 12:16
https://doi.org/10.1007/978-3-211-47104-3). Despite the significant efforts and understanding of the major pathways involved in the NDDs, there is no cure of these debilitating diseases. Presently, for the treatment of NDDs, some conventional drugs are available, but they are very expensive and in addition exhibit side effects. Since plant作者: Abnormal 時(shí)間: 2025-3-27 14:31
,Schlüsselfaktor Risikomanagement,ive stress is considered as an early biomarker for most NDDs and stopping it could prove to be an effective preventive strategy..In the present chapter, we have presented recent understanding related to the involvement of metabolic paradigm in NDD onset and progression.作者: 萬神殿 時(shí)間: 2025-3-27 21:24
https://doi.org/10.1007/978-3-211-47104-3 techniques are crucial in studying the state of NDDs, and designing of drugs according to the need of individual patient might be one of the biggest breakthroughs in the field of the disease..A comprehensive overview of the neuroimaging techniques along with their importance and impact in the key NDDs has been enlisted in the present chapter.作者: 細(xì)胞 時(shí)間: 2025-3-28 01:20
Involvement of Metabolic Paradigm in Progression of Neurodegenerative Diseases,ive stress is considered as an early biomarker for most NDDs and stopping it could prove to be an effective preventive strategy..In the present chapter, we have presented recent understanding related to the involvement of metabolic paradigm in NDD onset and progression.作者: 不可救藥 時(shí)間: 2025-3-28 03:01
An Overview of Imaging Techniques for Diagnosis of Debilitating Neurodegenerative Diseases, techniques are crucial in studying the state of NDDs, and designing of drugs according to the need of individual patient might be one of the biggest breakthroughs in the field of the disease..A comprehensive overview of the neuroimaging techniques along with their importance and impact in the key NDDs has been enlisted in the present chapter.作者: Fibrin 時(shí)間: 2025-3-28 09:28 作者: coltish 時(shí)間: 2025-3-28 13:01 作者: transplantation 時(shí)間: 2025-3-28 16:27
Cytostatische Substanzen und ihre Wirkungble intervention in the management of NDDs. In the present chapter, we have provided comprehensive details about neurodegenerative disease-specific metabolic alterations in glial cells. Further, effort has been made to provide possible therapeutic targets to regulate metabolic changes in glial cells to maintain brain homeostasis.作者: 緯線 時(shí)間: 2025-3-28 21:10
Cytostatische Substanzen und ihre Wirkunge Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc. We suggest that maintaining glucose metabolism can be a potential therapeutic target for the management of neurological disorders.作者: leniency 時(shí)間: 2025-3-29 02:23 作者: invade 時(shí)間: 2025-3-29 04:08 作者: 向前變橢圓 時(shí)間: 2025-3-29 10:39 作者: attenuate 時(shí)間: 2025-3-29 12:33 作者: Colonoscopy 時(shí)間: 2025-3-29 15:44 作者: 高歌 時(shí)間: 2025-3-29 22:22
Book 2024eases (NDDs), such as Alzheimer’s, Parkinson’s, Huntington’s disease, SCAs, SBMA, DRPLA, ALS, Freidrich Ataxia etc. The book also illustrates ?cellular and molecular mechanisms behind the key? neurodegenerative diseases and further expands on concept of unique and developing biomarkers associated wi作者: enmesh 時(shí)間: 2025-3-30 02:18 作者: 無能的人 時(shí)間: 2025-3-30 05:19
Grundlagen und Technologien des Ottomotorseurodegenerative diseases involve dysregulated lipid metabolism and oxidative stress; therefore, targeting lipid metabolism by drugs can provide a new perspective for treatment of the disease and, thereby, improvement of the patient’s quality of life.作者: 空洞 時(shí)間: 2025-3-30 08:39
https://doi.org/10.1007/978-3-211-47104-3 neurodegenerative diseases and these have been discussed in detail. Additionally, the molecular mechanisms associated with aggregation like posttranslational modifications, such as acetylation, phosphorylation, and ubiquitination have been also?described. Defects in the components of ubiquitin mach作者: 旅行路線 時(shí)間: 2025-3-30 12:56 作者: VAN 時(shí)間: 2025-3-30 16:50 作者: VEN 時(shí)間: 2025-3-30 23:36
Grundlagen und Technologien des Ottomotorsenerative disorders grows yearly, but effective treatments with few side effects remain limited. There is a new avenue of translational research, which evaluates the gut-brain-microbiome axis for management and therapeutic ideas for neurodegenerative disorders. It is therefore important to understan作者: impale 時(shí)間: 2025-3-31 04:27
Historie und Rahmenbedingungen,ccumulation of stress granules, neuroinflammation, perturbed immune response, and synaptic toxicity. Understanding the role of various cell signaling pathways and their crosstalk and signal integration in the pathogenesis of neurodegenerative diseases at the molecular level is critical for the devel
