標(biāo)題: Titlebook: Adrenoceptors; Jillian G. Baker,Martin C. Michel,Roger J. Summers Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusi [打印本頁] 作者: Cyclone 時間: 2025-3-21 17:10
書目名稱Adrenoceptors影響因子(影響力)
書目名稱Adrenoceptors影響因子(影響力)學(xué)科排名
書目名稱Adrenoceptors網(wǎng)絡(luò)公開度
書目名稱Adrenoceptors網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Adrenoceptors被引頻次
書目名稱Adrenoceptors被引頻次學(xué)科排名
書目名稱Adrenoceptors年度引用
書目名稱Adrenoceptors年度引用學(xué)科排名
書目名稱Adrenoceptors讀者反饋
書目名稱Adrenoceptors讀者反饋學(xué)科排名
作者: gentle 時間: 2025-3-21 22:56
Structures of Adrenoceptors,ne 2022) have been determined by X-ray crystallography and electron cryo-microscopy (cryo-EM) of all three βARs (β., β. and β.) and four out of six αARs (α., α., α., α.). The structures are in a number of different conformational states, including the inactive state bound to an antagonist, an interm作者: Sinus-Rhythm 時間: 2025-3-22 04:08
Genetic Variants of Adrenoceptors,ll nine corresponding adrenoceptor genes display genetic variation in their coding and adjacent non-coding genomic region. Coding variants, i.e., nucleotide exchanges within the transcribed and translated receptor sequence, may result in a difference in amino acid sequence thus altering receptor fun作者: 平淡而無味 時間: 2025-3-22 07:40 作者: AUGUR 時間: 2025-3-22 11:36 作者: 內(nèi)部 時間: 2025-3-22 15:03
Presynaptic Adrenoceptors, systems. Their activation by exogenous agonists leads to inhibition of the exocytotic release of noradrenaline and other transmitters from the neurons. Most often, the α.-receptor subtype is involved in this inhibition. The chain of molecular events between receptor occupation and inhibition of the作者: 宿醉 時間: 2025-3-22 20:59 作者: Evolve 時間: 2025-3-23 00:47 作者: Myocyte 時間: 2025-3-23 02:34 作者: 心胸開闊 時間: 2025-3-23 05:59
,Asthma and COPD: A Focus on β-Agonists – Past, Present and Future, the most common chronic non-communicable diseases worldwide. Chronic obstructive pulmonary disease (COPD), a leading cause of morbidity and mortality worldwide, is caused by exposure to tobacco smoke and other noxious particles and exerts a substantial economic and social burden. This chapter revie作者: Generalize 時間: 2025-3-23 13:40
,Adrenoceptors in the Eye – Physiological and Pathophysiological Relevance,orresponding receptors have been extensively studied and characterized in numerous ocular structures, including the cornea, conjunctiva, lacrimal gland, trabecular meshwork, uvea, and retina. These investigations have unveiled substantial clinical implications, particularly in the context of treatin作者: Magnificent 時間: 2025-3-23 16:47 作者: Intercept 時間: 2025-3-23 21:39 作者: orient 時間: 2025-3-24 02:06
Clinical Use of Adrenergic Receptor Ligands in Acute Care Settings,ettings. Adrenergic ligands exert their effects by interacting with the three major classes of adrenoceptors. Adrenoceptor agonists and antagonists have important applications, ranging from treatment of hypotension to asthma, and have proven to be extremely useful in a variety of clinical settings o作者: crescendo 時間: 2025-3-24 04:31
Adrenoceptor Expression and Function in the Endocrine Pancreas, nine adrenoceptor (AR) subtypes, the α.-AR appears to be the subtype most abundantly expressed in the human pancreas. While α.- and β-AR have opposing effects, the net response to sympathetic stimulation is inhibition of insulin secretion mediated by α.-AR located in the plasma membrane of pancreat作者: Explicate 時間: 2025-3-24 07:55
,β-Adrenoceptors in Cancer: Old Players and New Perspectives,-clinical models that distress causes a catecholaminergic overdrive that, mainly through the activation of β-adrenoceptors (β-ARs), results in cancer cell growth and cancer progression. In addition, clinical studies have evidenced a role of negative stress in cancer progression. Moreover, plenty of 作者: 最有利 時間: 2025-3-24 13:25 作者: Gleason-score 時間: 2025-3-24 17:48
Die Teilchenstruktur der Materie,hways. Finally, we highlight the importance of precise spatial and temporal control of adrenoceptor signalling that is controlled by the localisation of receptors at intracellular membranes and in larger protein complexes.作者: cardiac-arrest 時間: 2025-3-24 23:02 作者: 主動脈 時間: 2025-3-25 01:08
Signalling of Adrenoceptors: Canonical Pathways and New Paradigms,hways. Finally, we highlight the importance of precise spatial and temporal control of adrenoceptor signalling that is controlled by the localisation of receptors at intracellular membranes and in larger protein complexes.作者: CANON 時間: 2025-3-25 03:22
https://doi.org/10.1007/978-3-658-24469-9utlet resistance leading to voiding dysfunction in benign prostatic hyperplasia. α.-adrenoceptor antagonist such as tamsulosin is widely used as a first-line option to treat LUT symptoms in men, but it remains unclear to which extent and how smooth muscle relaxation contributes to symptom relief.作者: 個人長篇演說 時間: 2025-3-25 09:46
Adrenoceptors in the Lower Urinary Tract,utlet resistance leading to voiding dysfunction in benign prostatic hyperplasia. α.-adrenoceptor antagonist such as tamsulosin is widely used as a first-line option to treat LUT symptoms in men, but it remains unclear to which extent and how smooth muscle relaxation contributes to symptom relief.作者: 王得到 時間: 2025-3-25 12:00
Clinical Use of Adrenergic Receptor Ligands in Acute Care Settings,f acute care from the operating room to the critical care environment. Continued research interpreting the mechanisms of adrenoreceptors may help the discovery of new drugs with more desirable clinical profiles.作者: 違反 時間: 2025-3-25 17:33 作者: orthodox 時間: 2025-3-25 23:59 作者: 散步 時間: 2025-3-26 00:08 作者: 倔強不能 時間: 2025-3-26 05:24
,ANGEBOTSBEARBEITUNG IM SCHLüSSELFERTIGBAU,f acute care from the operating room to the critical care environment. Continued research interpreting the mechanisms of adrenoreceptors may help the discovery of new drugs with more desirable clinical profiles.作者: 學(xué)術(shù)討論會 時間: 2025-3-26 11:32
0171-2004 perts on various types of adrenoceptor research to provide concise insight into the current standing and future direction of uses of adrenoceptor-targeted drugs and research in this field.978-3-031-66778-7978-3-031-66776-3Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: 牽連 時間: 2025-3-26 12:59 作者: 過分自信 時間: 2025-3-26 20:25 作者: deforestation 時間: 2025-3-26 22:54
https://doi.org/10.1007/978-3-662-36952-4t by interrupting physiological autoinhibion of release. It belongs to the most effective antidepressive drugs. β.-Adrenoceptors are also localized on axon terminals in the peripheral and central nervous systems. Their activation leads to enhanced transmitter release, however, they are not activated作者: grotto 時間: 2025-3-27 03:41
https://doi.org/10.1007/978-3-662-36952-4variable blockade of β.-AR depending on relative affinity for β.-AR vs β.-AR. Since the introduction of β-blockers into clinical practice in 1965, β-blockers with different properties have been trialled, used and evaluated, leading to better understanding of their therapeutic effects and tolerabilit作者: GROG 時間: 2025-3-27 07:35
https://doi.org/10.1007/978-3-658-24469-9 longer first-line therapy after outcome trials did not demonstrate any benefits over and above other agents, despite similar blood pressure reductions. Angiotensin-converting enzyme inhibitors?(or angiotensin receptor blockers), calcium channel blockers, and thiazide-like diuretics are now consider作者: Feigned 時間: 2025-3-27 09:39
https://doi.org/10.1007/978-3-663-06879-2d are considered, including some with additional properties, and how the different pharmacological properties of current β2-agonists underpin their different places in treatment guidelines. Finally, it concludes with a look forward to future developments that could improve the β-agonists still furth作者: 財政 時間: 2025-3-27 16:56 作者: FECT 時間: 2025-3-27 21:37
https://doi.org/10.1007/978-3-658-27856-4on-deficit hyperactivity disorder, binge-eating disorder, and substance use disorder. In so doing, we highlight some unanswered questions that need to be resolved before it will be feasible to explain how changes in the function of any adrenoceptor subtype affect mood and behavior in humans and othe作者: 充足 時間: 2025-3-27 22:13
Grundlagen der Baubetriebslehre 1gic approaches are receiving attention in recent clinical studies: preserving noradrenaline levels (e.g., via reuptake inhibition) and direct activation of target adrenoceptors. Here, we review the expression and role of adrenoceptors in the brain, the preclinical studies which demonstrate that adre作者: FLIT 時間: 2025-3-28 04:26 作者: 心胸狹窄 時間: 2025-3-28 08:09 作者: 結(jié)束 時間: 2025-3-28 13:29
Structures of Adrenoceptors,o the molecular determinants for transducer coupling. This chapter will give a brief overview of the structures, receptor activation, a comparison across the different subfamilies and commonalities of ligand–receptor interactions.作者: Charade 時間: 2025-3-28 18:03 作者: savage 時間: 2025-3-28 20:24
Presynaptic Adrenoceptors,t by interrupting physiological autoinhibion of release. It belongs to the most effective antidepressive drugs. β.-Adrenoceptors are also localized on axon terminals in the peripheral and central nervous systems. Their activation leads to enhanced transmitter release, however, they are not activated作者: savage 時間: 2025-3-29 01:59
,Roles of β-adrenoceptor Subtypes and Therapeutics in Human Cardiovascular Disease: Heart Failure, Tvariable blockade of β.-AR depending on relative affinity for β.-AR vs β.-AR. Since the introduction of β-blockers into clinical practice in 1965, β-blockers with different properties have been trialled, used and evaluated, leading to better understanding of their therapeutic effects and tolerabilit作者: Hyaluronic-Acid 時間: 2025-3-29 03:42
Adrenoceptors and Hypertension, longer first-line therapy after outcome trials did not demonstrate any benefits over and above other agents, despite similar blood pressure reductions. Angiotensin-converting enzyme inhibitors?(or angiotensin receptor blockers), calcium channel blockers, and thiazide-like diuretics are now consider作者: 特別容易碎 時間: 2025-3-29 09:36 作者: Ovulation 時間: 2025-3-29 11:52 作者: Decongestant 時間: 2025-3-29 17:55 作者: BILK 時間: 2025-3-29 21:39
Locus Coeruleus and Noradrenergic Pharmacology in Neurodegenerative Disease,gic approaches are receiving attention in recent clinical studies: preserving noradrenaline levels (e.g., via reuptake inhibition) and direct activation of target adrenoceptors. Here, we review the expression and role of adrenoceptors in the brain, the preclinical studies which demonstrate that adre作者: 軌道 時間: 2025-3-30 00:45
Adrenoceptor Expression and Function in the Endocrine Pancreas, factor for the development of type 2 diabetes. Thus, the α.-AR was proposed as a drug target for the treatment of some forms of type 2 diabetes. Drug research and development programs leveraging this mechanism have reached the clinical stage, but none have resulted in an approved medicine due to a 作者: Hiatus 時間: 2025-3-30 06:29 作者: Ptsd429 時間: 2025-3-30 08:27
Jillian G. Baker,Martin C. Michel,Roger J. SummersAdrenoceptors have been prototypes for rationale drug design and receptor structure and function.Adrenoceptors are target of guideline-recommended drugs for >30 diseases from heart to prostate.Most re作者: FOLD 時間: 2025-3-30 12:55
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/b/image/167135.jpg作者: 公社 時間: 2025-3-30 18:58 作者: Acetaminophen 時間: 2025-3-30 21:51
https://doi.org/10.1007/978-3-7091-3214-2ne 2022) have been determined by X-ray crystallography and electron cryo-microscopy (cryo-EM) of all three βARs (β., β. and β.) and four out of six αARs (α., α., α., α.). The structures are in a number of different conformational states, including the inactive state bound to an antagonist, an interm作者: 注意到 時間: 2025-3-31 01:18
https://doi.org/10.1007/978-3-7091-3214-2ll nine corresponding adrenoceptor genes display genetic variation in their coding and adjacent non-coding genomic region. Coding variants, i.e., nucleotide exchanges within the transcribed and translated receptor sequence, may result in a difference in amino acid sequence thus altering receptor fun作者: bizarre 時間: 2025-3-31 05:48
https://doi.org/10.1007/978-3-662-36951-7are important therapeutic targets, over a century of effort has been put into developing drugs that modify their activity. This chapter provides an outline of how we have arrived at current knowledge of the receptors, their physiological roles and the methods used to develop ligands. Initial studies作者: 流動性 時間: 2025-3-31 09:36
