標(biāo)題: Titlebook: Autophagy: Biology and Diseases; Technology and Metho Zhiping Xie Book 2021 Science Press 2021 Autophagy.Autophagic Flux.Biomarkers.Drugs.A [打印本頁] 作者: 選民 時間: 2025-3-21 18:48
書目名稱Autophagy: Biology and Diseases影響因子(影響力)
書目名稱Autophagy: Biology and Diseases影響因子(影響力)學(xué)科排名
書目名稱Autophagy: Biology and Diseases網(wǎng)絡(luò)公開度
書目名稱Autophagy: Biology and Diseases網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Autophagy: Biology and Diseases被引頻次
書目名稱Autophagy: Biology and Diseases被引頻次學(xué)科排名
書目名稱Autophagy: Biology and Diseases年度引用
書目名稱Autophagy: Biology and Diseases年度引用學(xué)科排名
書目名稱Autophagy: Biology and Diseases讀者反饋
書目名稱Autophagy: Biology and Diseases讀者反饋學(xué)科排名
作者: Console 時間: 2025-3-21 21:26
Autophagosome Traffickingly includes cytoskeletal systems such as actin and microtubules, motor proteins such as myosins and the dynein-dynactin complex, and other proteins like LC3 on the membrane of autophagosomes. Factors regulating autophagosome trafficking have not been widely studied. To date the main reagents identif作者: 內(nèi)向者 時間: 2025-3-22 01:58
Mechanisms of Selective Autophagypes have been discovered and intensively studied, the precise ways in which the mechanisms of cargo recognition function remain mostly elusive. A fuller mechanistic understanding of selective autophagy will be important for efforts to promote disease treatment and drug development.作者: 舔食 時間: 2025-3-22 08:28
Monitoring Autophagy by Optical MicroscopyFP-LC3ΔG, can examine autophagy flux dynamically and quantitatively. In addition, the application of novel fluorophores such as Keima helps to detect the temporal and spatial characteristics of autophagy. Furthermore, selective autophagy can be clarified by labelling corresponding substrates and aut作者: apiary 時間: 2025-3-22 11:43 作者: 逃避責(zé)任 時間: 2025-3-22 12:56 作者: 感情 時間: 2025-3-22 17:23
Cell Models in Autophagy Researcha lower unicellular organism, it is unable to show tissue-specific regulation of autophagy. Cells from higher organisms, such as humans or other animals, are indispensable. Deeper and more extensive study of autophagy using cell models such as nervous tissue-derived cell models, epithelial tissue-de作者: Forehead-Lift 時間: 2025-3-22 22:47 作者: ROOF 時間: 2025-3-23 03:56 作者: 有害 時間: 2025-3-23 06:31 作者: synovium 時間: 2025-3-23 12:45 作者: Presbyopia 時間: 2025-3-23 15:29
,Unravelling Islanders’ Migration Stories,somes by immunofluorescence and electron microscopy. However, ignoring the dynamic characteristics of autophagy and only evaluating the number of autophagosomes or the presence of LC3B cannot completely reflect the activation or a blockage of the autophagy system, and objectively analyze its real ro作者: BORE 時間: 2025-3-23 19:08 作者: 庇護(hù) 時間: 2025-3-23 23:42 作者: NATAL 時間: 2025-3-24 03:38 作者: 流動才波動 時間: 2025-3-24 08:23 作者: rectocele 時間: 2025-3-24 14:00
https://doi.org/10.1007/978-3-663-20312-4itative manner. However, each biomarker has its specific significance and limitation. Therefore, the analysis of the autophagy level in cells or tissues through the detection of autophagy biomarkers should be carried out carefully.作者: Judicious 時間: 2025-3-24 17:04 作者: Permanent 時間: 2025-3-24 21:40
MicroRNAs Regulating Autophagy in Neurodegenerationegulating autophagy in NDs. Moreover, we will introduce basic strategies and techniques used in microRNA research. Delineation of the mechanisms contributing to NDs will result in development of better approaches for their early diagnosis and effective treatment.作者: 興奮過度 時間: 2025-3-25 00:22
Biomarkers of Autophagyitative manner. However, each biomarker has its specific significance and limitation. Therefore, the analysis of the autophagy level in cells or tissues through the detection of autophagy biomarkers should be carried out carefully.作者: Sleep-Paralysis 時間: 2025-3-25 03:18 作者: 絆住 時間: 2025-3-25 11:04
Book 2021ng, genomic, proteomic and bioinformatic approaches. The book is written and edited by a team of active scientists. It is intended as a practical reference resource for interested researchers to get started on autophagy studies.作者: 上釉彩 時間: 2025-3-25 13:44 作者: Arbitrary 時間: 2025-3-25 18:34
https://doi.org/10.1007/978-3-030-81018-4pletion. ATG proteins, membrane remodeling factors, and autophagic membranes follow a precise choreography to complete the overall process. In this chapter, we briefly discuss our current knowledge on the membrane origins of the autophagosome, as well as autophagosomal precursor generation, assembly, and expansion.作者: motor-unit 時間: 2025-3-25 20:55
The Big Five Personality Characteristicsotease protection assay with immunoblotting was used, accompanied by new techniques that were developed, including immunofluorescence assays, autophagosome completion assays, and the optogenetic closure assay. This study delivered our current understanding of phagophore closure and provided more reference methods to detect membrane closure.作者: 鞠躬 時間: 2025-3-26 03:25
Creativity, Incentives and Attitudes to Life cytoplasm-to-vacuole targeting (Cvt) pathway in yeast, and a special kind of autophagy, chloroplast autophagy, exists in plants. In conclusion, although autophagy is highly conserved in eukaryotes, there are still many differences between autophagy of animals, plants, and microorganisms.作者: 廚房里面 時間: 2025-3-26 07:08
The Challenge of Immortal Flesh,s can assist us in the exploration of the mechanism and therapeutic potential of autophagy regulation. In this chapter, we summarize the recent advances in chemical autophagy regulators to provide methodological support for autophagy research.作者: 清醒 時間: 2025-3-26 11:57 作者: 即席 時間: 2025-3-26 13:59 作者: Conflict 時間: 2025-3-26 16:49
Phagophore Closureotease protection assay with immunoblotting was used, accompanied by new techniques that were developed, including immunofluorescence assays, autophagosome completion assays, and the optogenetic closure assay. This study delivered our current understanding of phagophore closure and provided more reference methods to detect membrane closure.作者: Maximize 時間: 2025-3-26 21:37 作者: 抵制 時間: 2025-3-27 02:14
Chemical Autophagy Regulatorss can assist us in the exploration of the mechanism and therapeutic potential of autophagy regulation. In this chapter, we summarize the recent advances in chemical autophagy regulators to provide methodological support for autophagy research.作者: 小蟲 時間: 2025-3-27 08:12 作者: 四牛在彎曲 時間: 2025-3-27 09:34 作者: avenge 時間: 2025-3-27 15:08
Proteomics and Autophagy Researchially helpful to reveal the range of degradation substrates of autophagy through large-scale, unbiased analysis of cellular proteomes. At present, a variety of mass spectrometry-based proteomics methods have been successfully applied to autophagy research.作者: 衍生 時間: 2025-3-27 21:15 作者: landfill 時間: 2025-3-27 22:18
Book 2021) of autophagy. Volume 3 focuses on the technical aspects of autophagy research. It is comprised of two parts. The first part discusses the basic process of autophagy, including its overall classification and individual stages in the life cycle of autophagosomes. The second part discusses the tools,作者: 晚間 時間: 2025-3-28 04:31
Creativity, Incentives and Attitudes to LifeTPases, and SM proteins (Sec1/SM family proteins). This chapter will summarize the current knowledge of the key machinery involved in autophagosome-lysosome fusion, including autophagic SNAREs, involved ATG proteins, the HOPS complex, Rab GTPase, and other relevant aspects.作者: Diuretic 時間: 2025-3-28 09:34 作者: 生意行為 時間: 2025-3-28 11:56 作者: 縱火 時間: 2025-3-28 15:04
https://doi.org/10.1007/978-3-030-81018-4e assembly of the autophagosomal membrane precursors to form the phagophore, and phagophore elongation to complete the autophagosome. The sources of the autophagosomal membrane precursors are endomembrane compartments, such as the endoplasmic reticulum (ER), the ER-Golgi intermediate compartment (ER作者: META 時間: 2025-3-28 22:48 作者: ventilate 時間: 2025-3-29 02:29 作者: 極力證明 時間: 2025-3-29 04:30
https://doi.org/10.1007/978-3-030-81018-4 cellular components through engulfing portions of the cytoplasm or organelles and delivering them to the lysosomes/vacuole to be degraded. The trafficking of autophagosomes and their fusion with lysosomes are important steps that complete their maturation and degradation. In cells such as neuron, a作者: patriarch 時間: 2025-3-29 07:59 作者: euphoria 時間: 2025-3-29 11:56 作者: 舞蹈編排 時間: 2025-3-29 16:49 作者: OTTER 時間: 2025-3-29 22:42 作者: nepotism 時間: 2025-3-30 03:12 作者: 一再遛 時間: 2025-3-30 07:28
The ‘Romulus’ Amulet (for Elephantiasis)f knowledge about the aetiology of most NDs, only symptomatic treatment is available for patients. Hence, researchers and clinicians are in need of solid studies on pathological mechanisms of NDs. Autophagy promotes degradation of pathogenic proteins in NDs, while microRNAs post-transcriptionally re作者: xanthelasma 時間: 2025-3-30 10:25
https://doi.org/10.1007/978-3-663-20312-4f autophagy during normal physiological processes, pathogenic processes or pharmacological responses to drugs. In this chapter, some biomarkers of different types of autophagy, including macroautophagy, selective autophagy, chaperone-mediated autophagy, and microautophagy, as well as the lysosomal b作者: irreparable 時間: 2025-3-30 14:26
The Challenge of Immortal Flesh,dysfunction of autophagy is associated with a variety of human pathologies, including aging, cancer, neurodegenerative diseases, heart diseases, diabetes, and other metabolic diseases. Current research suggests that the regulation of autophagy may be a novel target for the treatment of these disease作者: 鈍劍 時間: 2025-3-30 17:24 作者: Expediency 時間: 2025-3-30 21:05
Rediscovering Some Stoic Argumentstion system for various cytoplasmic components but also functions selectively to clear damaged organelles, aggregated proteins, and invading pathogens (Feng et al., Cell Res 24:24–41, 2014; Galluzzi et al., EMBO J 36:1811–36, 2017; Klionsky et al., Autophagy 12:1–222, 2016). The malfunction of autop作者: Lethargic 時間: 2025-3-31 04:25 作者: mastopexy 時間: 2025-3-31 09:02
Greek Tragedy and the Contemporary Actors, mass spectrometry-based proteomic methods have become important and powerful tools for autophagy studies. These types of techniques have been especially helpful to reveal the range of degradation substrates of autophagy through large-scale, unbiased analysis of cellular proteomes. At present, a v作者: inchoate 時間: 2025-3-31 12:28 作者: 悲觀 時間: 2025-3-31 14:31 作者: LIMIT 時間: 2025-3-31 18:32
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/b/image/166847.jpg作者: 小母馬 時間: 2025-3-31 22:04 作者: 使高興 時間: 2025-4-1 05:06
Autophagosomal Membrane Origin and Formatione assembly of the autophagosomal membrane precursors to form the phagophore, and phagophore elongation to complete the autophagosome. The sources of the autophagosomal membrane precursors are endomembrane compartments, such as the endoplasmic reticulum (ER), the ER-Golgi intermediate compartment (ER
