作者: ARC 時間: 2025-3-21 21:18 作者: 一個姐姐 時間: 2025-3-22 00:46
Conference proceedings 1994anding of the origin of autoimmune diseases. Emphasized are cellular and molecular approaches in both organ-specific and systemic autoimmunity. A comprehensive bibliography, numerous illustrations, and tables make it an invaluable source of information for immunologists, rheumatologists, pathologists, dermatologists, and nephrologists.作者: fringe 時間: 2025-3-22 06:53 作者: Obligatory 時間: 2025-3-22 12:33
Tanja Grünberger,Anton-Rupert Laireiterpancreatic islets of langerhans (reviewed in Castano and Eisenbarth, 1990). The genetic and environmental factors which provoke this disease in humans remain largely unknown. Fortunately, the nonobese diabetic (NOD) mouse develops a spontaneous diabetes remarkably similar to that in humans and has t作者: POWER 時間: 2025-3-22 15:20
https://doi.org/10.1007/978-3-658-19973-9lerance is still unclear. Clonal deletion of self-reactive T cells during the thymic selection process has been described as one of the major mechanisms for inducing central tolerance (Kappler et al., 1987; von Boehmer, 1990). The presence of autoaggressive cells in healthy individuals as well as th作者: Strength 時間: 2025-3-22 17:40
Stand der Forschung und Erkenntnisinteresse,f cells from the mucosa and submucosal lymphocytic infiltration, is the underlying basis for pernicious anaemia, the most common cause of vitamin B12 deficiency in whites of northern European origin (Gleeson and Toh, 1991; Toh et al, 1992). The gastric parietal cell appears to be the principal cell 作者: 極大痛苦 時間: 2025-3-23 01:05 作者: patriot 時間: 2025-3-23 03:55 作者: 細胞 時間: 2025-3-23 06:12 作者: 鳴叫 時間: 2025-3-23 13:19
Gesund bleiben in kranken Unternehmenes, autoantibodies recognize discontinuous epitopes which are made up of amino acid residues that are not contiguous in sequence but are brought together by the folding of the polypeptide chain. Since, short synthetic peptides can, to a certain extent, mimic such conformational epitopes and they can作者: VOC 時間: 2025-3-23 14:56
https://doi.org/10.1007/978-3-658-39903-0n proposed to account for their production. Molecular mimicry is a well-established phenomenon which can involve exogenous antigens as well as autoantigens. An example of an exogenous antigen, i.e. a viral protein, was reported by Guldner et al. (1990). A 5-amino acid sequence of the p68 protein, a 作者: 侵略主義 時間: 2025-3-23 21:19 作者: 轉(zhuǎn)換 時間: 2025-3-23 22:36 作者: 愛國者 時間: 2025-3-24 05:46
https://doi.org/10.1007/978-3-642-57819-9e antibodies play a major role in the pathogenic mechanisms, since their titers correlate with disease activity and deposits of DNA/anti-DNA immune complexes are found in diseased organs (Tan, 1989). Furthermore, nephritis has been induced in SLE-prone mice by injection of monoclonal anti-dsDNA anti作者: 變形 時間: 2025-3-24 09:37
,Immunsystem — der sechste Sinn,unctional V.-D-J. unit. Selection is from among the six known V. families, which together comprise 100–200 genes (Berman et al, 1988; Schroeder et al, 1989), and the resulting recombinations in the B-cell population encode the functional repertoire. Since this repertoire can include autoantibodies, 作者: 氣候 時間: 2025-3-24 13:53 作者: Volatile-Oils 時間: 2025-3-24 17:47
https://doi.org/10.1007/978-3-476-04410-5ytes, macrophages and dendritic cells as well as proliferation of synovial cells. These cells and their products appear to be responsible for the chronic inflammatory processes in the joint. T cells are the major inflammatory cells in the rheumatoid inflammatory tissues (Abrahamsen et al. 1975). Sin作者: 甜得發(fā)膩 時間: 2025-3-24 19:19
https://doi.org/10.1007/978-3-476-04410-5finding of a highly restricted variable (V)α or Vβ usage by T cells from animals experimentally induced to respond to self antigens, such as myelin basic protein (MBP) (Acha-Orbea H., 1988) or type 2 collagen (David C.S., 1989, Chiocchia G., 1991), may not necessarily be true for spontaneously-trigg作者: Stress 時間: 2025-3-25 01:44
https://doi.org/10.1007/978-3-476-04410-5 a functional loss of the nicotinic acetylcholine receptor (AChR) in the postsynaptic membrane, which is the result of the effects of anti-AChR antibodies and complement (Lindstrom ., 1988). Many caucasian MG patients possess HLA-B8, and those having a subtype of the DR3 haplotype polymorphic at the作者: Vldl379 時間: 2025-3-25 04:29
,Verhaltens?nderungen erfolgreich umsetzen,blished by the American College of Rheumatology (Tan . 1982). There is compelling evidence that the genetic background plays an important role, not only in the susceptibility to the disease, but also in its clinical and serological expression (Arnett and Reveille 1992). The first association of SLE 作者: asthma 時間: 2025-3-25 08:37 作者: Aggregate 時間: 2025-3-25 11:46
https://doi.org/10.1007/978-3-642-78779-9Autoimmunkrankheit; Immunity; Immunologie; Immunology; Immunopathology; Immunpathologie; autoimmune diseas作者: incubus 時間: 2025-3-25 19:37 作者: harangue 時間: 2025-3-25 21:02
Autoimmunity: Experimental Aspects978-3-642-78779-9Series ISSN 1010-8793 作者: 萬神殿 時間: 2025-3-26 02:56 作者: 抱狗不敢前 時間: 2025-3-26 05:49
1010-8793 he understanding of the origin of autoimmune diseases. Emphasized are cellular and molecular approaches in both organ-specific and systemic autoimmunity. A comprehensive bibliography, numerous illustrations, and tables make it an invaluable source of information for immunologists, rheumatologists, p作者: 加強防衛(wèi) 時間: 2025-3-26 10:55 作者: 谷物 時間: 2025-3-26 14:31 作者: 披肩 時間: 2025-3-26 18:35 作者: Neutral-Spine 時間: 2025-3-26 21:50 作者: comely 時間: 2025-3-27 03:11
Kristin Kretzschmar,Antje Mohrmannet al., 1992). On the other hand, thymocytes are not deleted but rendered functionally incompetent (clonal anergy) when the self-antigens are exclusively expressed on thymic epithelial cells (Ramsdell et al., 1989; Salaun et al., 1990; Hoffmann et al., 1992; Sch?nrich et al., 1992a).作者: Tartar 時間: 2025-3-27 08:26 作者: 多山 時間: 2025-3-27 12:46
1010-8793 ty. A comprehensive bibliography, numerous illustrations, and tables make it an invaluable source of information for immunologists, rheumatologists, pathologists, dermatologists, and nephrologists.978-3-642-78781-2978-3-642-78779-9Series ISSN 1010-8793 作者: definition 時間: 2025-3-27 13:40 作者: HALO 時間: 2025-3-27 19:52 作者: Circumscribe 時間: 2025-3-27 23:01 作者: 下垂 時間: 2025-3-28 04:37
Tanja Grünberger,Anton-Rupert Laireiteriltration of lymphocytes into the islets, a process termed insulitis, followed by the destruction of the overwhelming majority of the beta cells, thereby, percipitating an overt diabetes. Autoimmune diabetes in NOD mice is under polygenic control, with the most important single contributor being the major histocompatibility complex (MHC) - ..作者: RUPT 時間: 2025-3-28 09:22 作者: 小淡水魚 時間: 2025-3-28 10:27
Conference proceedings 1994anding of the origin of autoimmune diseases. Emphasized are cellular and molecular approaches in both organ-specific and systemic autoimmunity. A comprehensive bibliography, numerous illustrations, and tables make it an invaluable source of information for immunologists, rheumatologists, pathologist作者: 骯臟 時間: 2025-3-28 16:10 作者: 激勵 時間: 2025-3-28 19:43 作者: 壓艙物 時間: 2025-3-29 02:15
Role of Immunocompetent Cells in Skin Sclerosis and Autoimmunity in Tight Skin Micesia. Although, the exact mechanisms involved in the pathogenesis of SSc are not known, the following three major alterations might play a role in the pathogenesis:.The autoimmune manifestations in scleroderma are characterized by the presence of autoantibodies as well as by abnormalities of cellular immune response.作者: 反對 時間: 2025-3-29 06:04
Tolerance induction in mature peripheral T cells T lymphocytes. The enormous diversity of the receptor repertoire is achieved by random rearrangement of DNA segments. In this process specificities for non-self as well as for self-determinants are created. T lymphocytes with high affinity for self-antigens are physically eliminated when they devel作者: 以煙熏消毒 時間: 2025-3-29 10:46
Transgenic mice carrying the rearranged T cell receptor of a diabetogenic T cell clonepancreatic islets of langerhans (reviewed in Castano and Eisenbarth, 1990). The genetic and environmental factors which provoke this disease in humans remain largely unknown. Fortunately, the nonobese diabetic (NOD) mouse develops a spontaneous diabetes remarkably similar to that in humans and has t作者: ALT 時間: 2025-3-29 12:19
The maintenance and reestablishment of self-tolerance: T cell receptor (TCR) peptide-specific regulalerance is still unclear. Clonal deletion of self-reactive T cells during the thymic selection process has been described as one of the major mechanisms for inducing central tolerance (Kappler et al., 1987; von Boehmer, 1990). The presence of autoaggressive cells in healthy individuals as well as th作者: LUMEN 時間: 2025-3-29 19:31
Prevention of gastric autoimmunity by transgenic expression of a proton pump subunit in the thymusf cells from the mucosa and submucosal lymphocytic infiltration, is the underlying basis for pernicious anaemia, the most common cause of vitamin B12 deficiency in whites of northern European origin (Gleeson and Toh, 1991; Toh et al, 1992). The gastric parietal cell appears to be the principal cell 作者: Pepsin 時間: 2025-3-29 20:27
The Anti-Self B Cell Repertoirehe expressed V. gene repertoire of normal humans. The results of a number of different experiments suggest that the phenomenon of repertoire restriction is due to clonal selection at the level of both mature and immature B cells. For instance, in examining sequences of the over-represented V. genes 作者: 沙漠 時間: 2025-3-30 01:26
In vivo suppression of IgG2ab production accomplished by CD4+8? Th1 cell clones specific for a γ2ab en implicated in idiotypic network immune regulation (Jerne 1974), in the pathogenesis of autoimmune diseases (Hannestad and Kristoffersen, 1988; Hannestad et al, 1992), and immune surveillance of B cell neoplasms (Lynch et al, 1972; J?rgensen et al, 1980). Furthermore, IgG Fc regions are the target作者: 討好女人 時間: 2025-3-30 04:21 作者: 生命層 時間: 2025-3-30 09:29 作者: 在前面 時間: 2025-3-30 14:37 作者: 慢跑鞋 時間: 2025-3-30 19:16
The Expression of Heat Shock Proteins in Systemic Lupus Erythematosusd that it consisted of the rapid synthesis of a small number of new proteins - the heat shock proteins (hsps) - against a background of repressed general protein synthesis, upon exposure of organisms to a variety of insults. These include hypoxia, glucose deprivation or supplementation, amino acid a作者: inflame 時間: 2025-3-30 22:38 作者: obsession 時間: 2025-3-31 01:43 作者: 黃油沒有 時間: 2025-3-31 05:15
Differential usage of an autoantibody-associated VH gene by human B-cell tumorsunctional V.-D-J. unit. Selection is from among the six known V. families, which together comprise 100–200 genes (Berman et al, 1988; Schroeder et al, 1989), and the resulting recombinations in the B-cell population encode the functional repertoire. Since this repertoire can include autoantibodies, 作者: inconceivable 時間: 2025-3-31 11:21 作者: 話 時間: 2025-3-31 16:31
T cell receptor variable gene repertoire in rheumatoid synovial T cells responding to BCGytes, macrophages and dendritic cells as well as proliferation of synovial cells. These cells and their products appear to be responsible for the chronic inflammatory processes in the joint. T cells are the major inflammatory cells in the rheumatoid inflammatory tissues (Abrahamsen et al. 1975). Sin作者: 供過于求 時間: 2025-3-31 17:34 作者: Palate 時間: 2025-3-31 22:35 作者: Melanoma 時間: 2025-4-1 04:18
Genetic and environmental factors in Systemic lupus erythematosusblished by the American College of Rheumatology (Tan . 1982). There is compelling evidence that the genetic background plays an important role, not only in the susceptibility to the disease, but also in its clinical and serological expression (Arnett and Reveille 1992). The first association of SLE 作者: CRUC 時間: 2025-4-1 06:49
Role of Immunocompetent Cells in Skin Sclerosis and Autoimmunity in Tight Skin Micemajor clinical forms ranging from limited skin involvement (morphea) to diffuse skin sclerosis and severe internal organ involvement (progressive skin sclerosis, SSc) and CREST syndrome in which skin sclerosis is associated with calcinosis, Raynaud phenomenon, esophageal densitometry and telangiecta作者: gait-cycle 時間: 2025-4-1 11:11
https://doi.org/10.1007/978-3-658-19973-9e cells are not tolerized at the outset, but rather become activated normally and then controlled by regulatory T cells. Thus the equilibrium between autoreactive and regulatory T cells may determine the expression of autoimmunity.作者: 領導權 時間: 2025-4-1 16:50 作者: 拉開這車床 時間: 2025-4-1 20:28 作者: Incisor 時間: 2025-4-1 23:49
Ulrike Morgenstern,Michaela Moserimal models, antigen stimulated T-cells and antigen specific T-cell clones derived from animals with arthritis are able to induce a similar illness in naive animals (Holoshitz et al, 1983; Stuart et al, 1984).
