標(biāo)題: Titlebook: Autoimmunity; Methods and Protocol Andras Perl Book 20041st edition Humana Press 2004 [打印本頁(yè)] 作者: coerce 時(shí)間: 2025-3-21 18:31
書目名稱Autoimmunity影響因子(影響力)
書目名稱Autoimmunity影響因子(影響力)學(xué)科排名
書目名稱Autoimmunity網(wǎng)絡(luò)公開度
書目名稱Autoimmunity網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Autoimmunity被引頻次
書目名稱Autoimmunity被引頻次學(xué)科排名
書目名稱Autoimmunity年度引用
書目名稱Autoimmunity年度引用學(xué)科排名
書目名稱Autoimmunity讀者反饋
書目名稱Autoimmunity讀者反饋學(xué)科排名
作者: Limited 時(shí)間: 2025-3-21 20:24 作者: 責(zé)怪 時(shí)間: 2025-3-22 01:12 作者: 誹謗 時(shí)間: 2025-3-22 07:39 作者: IST 時(shí)間: 2025-3-22 12:04
Die Bestimmung gesteinsbildender Minerale system, tolerance mechanisms develop that prevent or inhibit potentially harmful reactivities to self-antigens. Autoreactive B and T cells that are generated during immune responses are eliminated by apoptosis in the thymus, lymph nodes, or peripheral circulation or are actively suppressed by regul作者: 傲慢人 時(shí)間: 2025-3-22 14:39 作者: 滔滔不絕的人 時(shí)間: 2025-3-22 18:34 作者: Dissonance 時(shí)間: 2025-3-22 23:41 作者: BET 時(shí)間: 2025-3-23 02:14
Erfahrungen beim Ersten Aufstau,as led to the characterization of a signaling defect, involving protein kinase A (PKA), leading to abnormal T-cell effector functions in SLE. PKA is a component of the adenylyl cyclase/cyclic adenosine monophosphate/PKA (AC/cAMP/PKA) pathway, a principal signal transduction system in T cells. The ai作者: 高興去去 時(shí)間: 2025-3-23 07:00
Erfahrungen beim Ersten Aufstau,n, or death of cells of the immune system are dependent on controlled reactive oxygen intermediate (ROI) production and ATP synthesis in mitochondria. The mitochondrial transmembrane potential (ΔΨ.) reflects the energy stored in the electrochemical gradient across the inner mitochondrial membrane, w作者: 失望未來 時(shí)間: 2025-3-23 09:42 作者: Concomitant 時(shí)間: 2025-3-23 16:23
Joachim Holtz,Ulrich Schwellenbergmpaired immunoregulation and tissue damage. Characterization of the expression and function of cytokines is important for elucidation of pathogenic mechanisms and for identification of therapeutic targets and strategies. We reviewed the utility of assays that reflect individual variability in cytoki作者: Countermand 時(shí)間: 2025-3-23 18:40
Capacità di comando: leadershipB-cell epitope mapping, and detection of transaldolase-specific antibodies in patients with multiple sclerosis are described. Recombinant transaldolase was produced in a prokaryotic expression vector for use in Western blot analysis of sera of these patients. Overlapping transaldolase peptides 15 am作者: 鎮(zhèn)壓 時(shí)間: 2025-3-24 02:05 作者: Obstreperous 時(shí)間: 2025-3-24 04:07 作者: Proclaim 時(shí)間: 2025-3-24 08:05
L’attenzione: al centro della coscienzaers. These T-cell clones allow the rapid induction of tissue-specific autoimmunity with the intent of dissecting the contribution of the different cell types involved. T cells from the diabetes-prone nonobese diabetic mouse are proving to be a vital asset for understanding the T-cell-mediated pathog作者: 先行 時(shí)間: 2025-3-24 11:27 作者: 污點(diǎn) 時(shí)間: 2025-3-24 16:45 作者: 現(xiàn)存 時(shí)間: 2025-3-24 20:46
,Factor de éxito Aprendizaje e Innovación,. T cells causes autoreactivity specific to the major histocompatibility complex in vitro. The lupus-inducing drugs hydralazine and procainamide also inhibit T-cell DNA methylation and induce autoreactivity, and T cells from patients with active lupus have hypomethylated DNA and a similarly autoreac作者: adduction 時(shí)間: 2025-3-25 01:07 作者: Nefarious 時(shí)間: 2025-3-25 07:25
Gestión de la Cooperación en la Prácticausceptible murine strains. The model is called proteoglycan-induced arthritis (PGIA) because the antigenic/arthritogenic material is isolated from cartilage. This autoimmune systemic disease is induced by intraperitoneal immunization of either BALB/c or certain C3H colonies with cartilage proteoglyc作者: 要塞 時(shí)間: 2025-3-25 09:05
Experimental Use of Murine Lupus Modelsphenotypes span the broad range of clinical manifestations of human lupus and consist of both spontaneous and experimentally induced disease in both inbred and targeted mutant animals. This chapter contrasts the clinical characteristics of these various models, providing an outline for the use and analysis of these in vivo autoimmune systems.作者: aplomb 時(shí)間: 2025-3-25 11:53
1543-1894 ntgy?rgyi Autoimmunity: Methods and Protocols is intended to serve as a ready-to-use guide to establish and interrogate human and animal models of autoimmune diseases. The first chapter, “Pathogenesis and Spectrum of Autoimmunity,” discusses major hypotheses driving this most tantalizing area of res作者: 不能強(qiáng)迫我 時(shí)間: 2025-3-25 16:52 作者: BRACE 時(shí)間: 2025-3-25 20:42
The Anti-DNA Knock-In Model of Systemic Autoimmunity Induced by the Chronic Graft-vs-Host Reactionrs of serum anti-DNA antibodies appear and the mice develop renal damage. This permits the examination of the role of somatic immunoglobulin genetics and B-cell tolerance in a model of systemic lupus erythematosus.作者: GRAVE 時(shí)間: 2025-3-26 01:10
Gestión de la Cooperación en la Prácticars of serum anti-DNA antibodies appear and the mice develop renal damage. This permits the examination of the role of somatic immunoglobulin genetics and B-cell tolerance in a model of systemic lupus erythematosus.作者: 半球 時(shí)間: 2025-3-26 04:29 作者: Vulvodynia 時(shí)間: 2025-3-26 10:44
Einteilung und Entstehung der Gesteineished for many genetic intervals. SLE is a complex clinical illness, and investigation of the genetics of the illness based on clinical manifestations revealed linkages not found without consideration of the phenotype of the disease.作者: resistant 時(shí)間: 2025-3-26 14:57
https://doi.org/10.1007/978-3-322-87683-6small molecule drug treatments, death receptor ligation, and exposure to granule components of cytotoxic lymphocytes. Assays to confirm the induction of apoptosis by quantifying changes in mitochondrial membrane potential, phosphatidylserine membrane localization, DNA content, and autoantigen cleavage are also detailed.作者: 痛苦一生 時(shí)間: 2025-3-26 19:05 作者: 可卡 時(shí)間: 2025-3-26 23:00
Pathogenesis and Spectrum of Autoimmunitycryptic epitopes of self-antigens or aberrant lymphokine production. Development of immune responses and tolerance is determined by an interplay of genetic and environmental factors. Autoimmunity is a result of the breakdown of one or more of the mechanisms of immune tolerance.作者: jettison 時(shí)間: 2025-3-27 01:19
Mapping the Systemic Lupus Erythematosus Susceptibility Genesished for many genetic intervals. SLE is a complex clinical illness, and investigation of the genetics of the illness based on clinical manifestations revealed linkages not found without consideration of the phenotype of the disease.作者: Extemporize 時(shí)間: 2025-3-27 08:02
Methods for Inducing Apoptosissmall molecule drug treatments, death receptor ligation, and exposure to granule components of cytotoxic lymphocytes. Assays to confirm the induction of apoptosis by quantifying changes in mitochondrial membrane potential, phosphatidylserine membrane localization, DNA content, and autoantigen cleavage are also detailed.作者: 盲信者 時(shí)間: 2025-3-27 12:20
Measurement of Cytokines in Autoimmune Diseasenes. Real-time reverse transcriptase polymerase chain reaction and intracellular staining for cytokine expression are two sensitive and quantitative approaches for analysis of cytokine mRNA and protein, respectively. Detailed methods are provided for these assays.作者: 緩解 時(shí)間: 2025-3-27 16:43
Erfahrungen beim Ersten Aufstau,otting to identify the presence of regulatory (R)-subunit proteins of PKA, and (c) isolation of RNA, and quantification of PKA R subunit-specific transcripts by competitive polymerase chain reaction. Although our emphasis in the chapter is T cells, these methods may be useful for investigation of signaling via PKA in other cell types as well.作者: GNAW 時(shí)間: 2025-3-27 21:44 作者: obtuse 時(shí)間: 2025-3-28 01:07 作者: Epidural-Space 時(shí)間: 2025-3-28 05:18 作者: aptitude 時(shí)間: 2025-3-28 06:23 作者: anaphylaxis 時(shí)間: 2025-3-28 13:42 作者: 宣誓書 時(shí)間: 2025-3-28 17:28
T-Cell Signaling Abnormalities in Human Systemic Lupus Erythematosuserythematosus (SLE). T-cell receptor (TCR)/CD3-mediated stimulation of SLE T cells shows increased protein tyrosine phosphorylation of cellular proteins, with faster kinetics, heightened calcium response, and decreased interleukin (IL)-2 production. The molecular mechanism of T-cell signaling abnorm作者: 小淡水魚 時(shí)間: 2025-3-28 22:10
TCR ζ-Chain Abnormalities in Human Systemic Lupus Erythematosus (SLE). Although aberrant expression of signaling molecules may arise intrinsically or in response to the environment, these abnormalities play a significant role in the pathogenesis of this autoimmune disease. Modern research on lymphocyte signaling abnormalities in SLE has been directed toward ide作者: 廚房里面 時(shí)間: 2025-3-29 01:30
Protein Kinase A and Signal Transduction in T Lymphocytesas led to the characterization of a signaling defect, involving protein kinase A (PKA), leading to abnormal T-cell effector functions in SLE. PKA is a component of the adenylyl cyclase/cyclic adenosine monophosphate/PKA (AC/cAMP/PKA) pathway, a principal signal transduction system in T cells. The ai作者: 輕打 時(shí)間: 2025-3-29 04:03 作者: 暴行 時(shí)間: 2025-3-29 09:17
Methods for Inducing Apoptosisnerate a novel source of antigens against which an autoimmune response may be initiated. In our laboratory, we study the biochemistry and cell biology of systemic autoimmune disease autoantigens during different forms of cell death. Several different methods for inducing apoptosis, and for assaying 作者: Trypsin 時(shí)間: 2025-3-29 14:04
Measurement of Cytokines in Autoimmune Diseasempaired immunoregulation and tissue damage. Characterization of the expression and function of cytokines is important for elucidation of pathogenic mechanisms and for identification of therapeutic targets and strategies. We reviewed the utility of assays that reflect individual variability in cytoki作者: 共同給與 時(shí)間: 2025-3-29 17:31 作者: MAG 時(shí)間: 2025-3-29 20:31 作者: aspect 時(shí)間: 2025-3-30 03:29 作者: Commemorate 時(shí)間: 2025-3-30 06:43 作者: Arthropathy 時(shí)間: 2025-3-30 11:50
Experimental Use of Murine Lupus Modelsphenotypes span the broad range of clinical manifestations of human lupus and consist of both spontaneous and experimentally induced disease in both inbred and targeted mutant animals. This chapter contrasts the clinical characteristics of these various models, providing an outline for the use and a作者: 飛鏢 時(shí)間: 2025-3-30 14:59 作者: 擦掉 時(shí)間: 2025-3-30 19:45 作者: DAMN 時(shí)間: 2025-3-31 00:00 作者: 租約 時(shí)間: 2025-3-31 01:04 作者: Defraud 時(shí)間: 2025-3-31 06:02
1543-1894 evance of the model for a particular disease and for autoimmunity in general. Part I contains methods and protocols to assess immunological and biochemical pathways relevant for disease pathoge978-1-59259-805-2Series ISSN 1543-1894 Series E-ISSN 1940-6037 作者: Basilar-Artery 時(shí)間: 2025-3-31 12:23
,MoviA – Mobile virtuelle Absicherung,odulation of membrane clustering, aberrant cellular distribution, and precompartmentalization with lipid rafts invariably contributing to abnormal T-cell signaling in SLE T cells. The methods and protocols described here pertaining to T-cell signaling abnormalities in SLE T cells are very much optim作者: Electrolysis 時(shí)間: 2025-3-31 13:38
,MoviA – Mobile virtuelle Absicherung,ression of numerous signaling molecules in SLE T cells. The contribution of each of these mechanisms in the abnormal expression of signaling molecules in SLE T cells is not known. In addition to abnormalities in gene expression, multiple factors, including altered cellular distribution of the protei作者: 追蹤 時(shí)間: 2025-3-31 18:26
Erfahrungen beim Ersten Aufstau,s of intracellular glutathione and ATP. Oxidative stress affects signaling through the T-cell receptor as well as the activity of redox-sensitive caspases. ATP depletion may be responsible for diminished activation-induced apoptosis and sensitize lupus T cells to necrosis. Mitochondrial dysfunction 作者: mettlesome 時(shí)間: 2025-3-31 23:24
https://doi.org/10.1007/978-88-470-2799-2t (FCA)is injected subcutaneously into mice. The immune response, the histological changes, and the genetic susceptibility seen in EAM are similar to those of CB3-induced myocarditis. The third model is experimental autoimmune thyroiditis (EAT). EAT can be induced in genetically susceptible strains 作者: lymphedema 時(shí)間: 2025-4-1 03:06
Capacità di comando: leadership are discussed. Along with these topics, a protocol of peptide-induced diabetes and peptide vaccine-induced anaphylaxis are described, serving as a reminder of the potential dangers that could exist in human trials. In summary, animal models have become necessary in the study of type 1 diabetes and 作者: RADE 時(shí)間: 2025-4-1 07:57 作者: 厭食癥 時(shí)間: 2025-4-1 11:15
