標題: Titlebook: Autoimmunity; Methods and Protocol Andras Perl Book 2012Latest edition Springer Science+Business Media New York 2012 T-cell receptor.allerg [打印本頁] 作者: mortality 時間: 2025-3-21 16:42
書目名稱Autoimmunity影響因子(影響力)
書目名稱Autoimmunity影響因子(影響力)學科排名
書目名稱Autoimmunity網(wǎng)絡公開度
書目名稱Autoimmunity網(wǎng)絡公開度學科排名
書目名稱Autoimmunity被引頻次
書目名稱Autoimmunity被引頻次學科排名
書目名稱Autoimmunity年度引用
書目名稱Autoimmunity年度引用學科排名
書目名稱Autoimmunity讀者反饋
書目名稱Autoimmunity讀者反饋學科排名
作者: 混合,攙雜 時間: 2025-3-21 22:46 作者: Exposure 時間: 2025-3-22 00:30 作者: Constrain 時間: 2025-3-22 07:11
Assessment of Mitochondrial Dysfunction in Lymphocytes of Patients with Systemic Lupus Erythematosun, or death of cells of the immune system is dependent on controlled reactive oxygen intermediates (ROI) production and ATP synthesis in mitochondria. The mitochondrial transmembrane potential (?..) reflects the energy stored in the electrochemical gradient across the inner mitochondrial membrane wh作者: Allege 時間: 2025-3-22 09:53
The Role of Endocytic Recycling in Autoimmunity,ave reduced expression of T cell antigen receptor (TCR) at the surface. The amount of TCR expressed at the surface of a T cell directly determines the ability of a T cell to become activated. The endocytic recycling machinery regulates transport of T cell receptors to the plasma membrane, internaliz作者: pineal-gland 時間: 2025-3-22 13:25 作者: SIT 時間: 2025-3-22 17:10 作者: amenity 時間: 2025-3-22 23:13
,Murine Models of Lupus Induced by Hypomethylated T Cells (DNA Hypomethylation and Lupus…),+ T cells causes MHC-specific autoreactivity in vitro. The lupus-inducing drugs hydralazine and procainamide also inhibit T cell DNA methylation and induce autoreactivity, and T cells from patients with active lupus have hypomethylated DNA and a similarly autoreactive T cell subset. Further, T cells作者: spondylosis 時間: 2025-3-23 02:54 作者: 熱心助人 時間: 2025-3-23 06:28
Analysis of Renal Mononuclear Phagocytes in Murine Models of SLE,hese cells is associated with the onset of clinical disease in mice and infiltration with these cells is associated with poor prognosis in humans. Using magnetic beads followed by flow cytometric sorting, pure populations of cells are obtained that are functional in a variety of assays. Sufficient n作者: lobster 時間: 2025-3-23 09:47
A Murine Autoimmune Model of Rheumatoid Arthritis and Systemic Lupus Erythematosus Associated with Lupus Erythematosus (SLE). In this chapter we describe a murine model where deregulated production of IL-17 and IL-21 can lead to either lupus-like disease or RA-like symptoms depending on the genetic background. We delineate the key techniques that can be used to dissect the mechanisms responsible作者: 小木槌 時間: 2025-3-23 15:55
The Parent-into-F1 Murine Model in the Study of Lupus-Like Autoimmunity and CD8 Cytotoxic T Lymphoc a graft-vs.-host disease (GVHD) that takes one of the following two forms: (a) acute GVHD seen with B6 → F1 mice and mediated by donor CD8 cytotoxic T cells that eliminate host lymphocytes and (b) a chronic lupus-like GVHD seen with DBA → F1 mice and mediated by donor CD4 T cell cognate help to aut作者: Postulate 時間: 2025-3-23 19:18
Genetic Approach to Study Lupus Glomerulonephritis,nifestation of SLE, involves inflammation in the kidney leading to loss of renal function. However, it is not clear what controls the progression of lupus nephritis; this is an important research question, considering its implications in clinical treatment of lupus nephritis. Finding genes that unde作者: 有惡臭 時間: 2025-3-24 00:56
Animal Models of Primary Biliary Cirrhosis: Materials and Methods,ic bile ducts and the presence of antimitochondrial antibodies (AMAs). There have been limited advances in understanding the molecular pathogenesis of the disease because of the difficulty in accessing human tissues and the absence of appropriate animal models. Recently, several unique murine models作者: achlorhydria 時間: 2025-3-24 04:40 作者: 推遲 時間: 2025-3-24 09:52
Flow Cytometric Identification of Fibrocytes in Scleroderma Lung Disease,nary complications including interstitial lung disease have emerged as the greatest cause of mortality in this disease. Because treatments are limited, new areas of investigation are sorely needed. An emerging area of interest in this field is a potential role for fibrocytes as biomarkers or mediato作者: 摘要記錄 時間: 2025-3-24 12:26
Oxidative Stress and Beta Cell Dysfunction,in-producing islet beta cells. Pancreatic islet cell inflammation, or insulitis, precedes beta cell death and T1D onset. In the insulitic lesion, innate immune cells produce chemokines and cytokines that recruit and activate adaptive immune cells (Eizirik D et al., Nat Rev Endocrinol 5:219–226, 2009作者: monochromatic 時間: 2025-3-24 15:41 作者: 壓艙物 時間: 2025-3-24 22:22 作者: Anterior 時間: 2025-3-25 01:01
Experimental Use of Mouse Models of Systemic Lupus Erythematosus,mmon endpoints examined in experimental studies, but exhibit specific differences in the incidence of other end-organ manifestations such as hemolytic anemia, arthritis, dermatitis, and vasculitis. This chapter contrasts the clinical characteristics of these various models, providing an outline for their use and analysis.作者: Interferons 時間: 2025-3-25 06:31
Analysis of Renal Mononuclear Phagocytes in Murine Models of SLE,umbers of cells are obtained for genomic characterization. An analysis of the function of these cells should lead to a better understanding of the inflammatory processes that cause renal impairment in SLE and other renal inflammatory diseases.作者: Ige326 時間: 2025-3-25 07:58
Modeling Innate Immunity in Murine Skin: Utilization of Subcutaneous Osmotic Pumps for Inflammatory utilizing osmotic pumps to deliver innate immune stimuli to subcutaneous tissue. Subcutaneous osmotic pumps provide a flexible system for studying innate immunity in the skin as well as the affects of other ligands on skin inflammation and fibrosis.作者: Amylase 時間: 2025-3-25 12:33 作者: 雀斑 時間: 2025-3-25 19:02
Einteilung und Entstehung der Gesteine cell reagent panels for multiparameter flow cytometry, and combine their use with advanced bioinformatics strategies that together will likely be advantageous for improving the characterization, prognosis, and for possibly improving treatment regimens of chronic inflammatory diseases such as lupus.作者: municipality 時間: 2025-3-25 21:31 作者: COMMA 時間: 2025-3-26 01:46 作者: ESO 時間: 2025-3-26 05:02 作者: Acetaldehyde 時間: 2025-3-26 12:20 作者: 強制令 時間: 2025-3-26 14:27
Die Bestimmung gesteinsbildender Minerale of RA and SLE in murine models. Given the broad involvement of deregulated production of IL-17 and IL-21 in autoimmunity, many of these techniques could also be valuable for the investigation of these pathways in murine models of other autoimmune diseases.作者: Buttress 時間: 2025-3-26 18:01
The Role of Endocytic Recycling in Autoimmunity,hods used to investigate endocytic recycling of the TCR, CD4, and CD8 co-receptors in peripheral blood lymphocytes, T cells, and in splenocytes from lupus-prone murine models. The assays described will allow the study of surface receptor turnover in live untouched lymphocytes by flow cytometry.作者: ORBIT 時間: 2025-3-27 00:54 作者: medieval 時間: 2025-3-27 01:20
Die Bestimmung gesteinsbildender Mineralemmon endpoints examined in experimental studies, but exhibit specific differences in the incidence of other end-organ manifestations such as hemolytic anemia, arthritis, dermatitis, and vasculitis. This chapter contrasts the clinical characteristics of these various models, providing an outline for their use and analysis.作者: 悠然 時間: 2025-3-27 09:00
https://doi.org/10.1007/978-3-8274-2223-1umbers of cells are obtained for genomic characterization. An analysis of the function of these cells should lead to a better understanding of the inflammatory processes that cause renal impairment in SLE and other renal inflammatory diseases.作者: Emg827 時間: 2025-3-27 10:34
Einteilung und Entstehung der Gesteine utilizing osmotic pumps to deliver innate immune stimuli to subcutaneous tissue. Subcutaneous osmotic pumps provide a flexible system for studying innate immunity in the skin as well as the affects of other ligands on skin inflammation and fibrosis.作者: Respond 時間: 2025-3-27 13:58
1064-3745 al for reproducible results.Contains key notes and implement.Continued refinement of?wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease. The seco作者: guzzle 時間: 2025-3-27 20:58 作者: COLIC 時間: 2025-3-27 23:20
Die Bestimmung gesteinsbildender MineraleWork on about ten previously identified associations has been published using this resource. Genome-wide association studies cannot identify rare SNPs or mutations, which may impart greater relative risks than common variants. Much of the genetics of lupus may be from rare variants or mutations. In 作者: 對手 時間: 2025-3-28 03:12
Einteilung und Entstehung der Gesteine clustering, aberrant cellular distribution, and pre-compartmentalization with lipid-rafts. The methods and protocols described here pertaining to T cell signaling abnormalities in SLE T cells are optimized in many ways and are derived by the combined task and continuous efforts of many researchers 作者: instructive 時間: 2025-3-28 10:08
https://doi.org/10.1007/978-3-8274-2223-1ellular glutathione and ATP. Increased production of nitric oxide has been identified as a cause of MHP and increased mitochondrial biogenesis. Oxidative stress affects signaling through the T cell receptor as well as activity of redox--sensitive caspases. ATP depletion causes diminished activation-作者: VOC 時間: 2025-3-28 10:55
Die Bestimmung gesteinsbildender Mineraleocainamide and hydralazine develop a lupus-like disease. Further, transgenic mice with an inducible T cell DNA methylation defect also develop lupus-like autoimmunity. This chapter describes the protocols for inducing autoreactivity in murine T cells in vitro and for inducing autoimmunity in vivo us作者: Abrupt 時間: 2025-3-28 15:40
https://doi.org/10.1007/978-3-8274-2223-1of antibody from dam to fetus, (5) blocking NMDAR-mediated pathogenicity in vivo, (6) evacuation of blood from the brain by cardiac perfusion to preserve the brain for histology, (7) evaluating injured/apoptotic neurons in brain histology, (8) preparing membrane-enriched brain -fractions for NMDAR a作者: 慢慢沖刷 時間: 2025-3-28 19:18
Die Bestimmung gesteinsbildender Mineralel function will convert acute GVHD to chronic GVHD in B6 → F1 mice. Conversely, agents that promote CD8 CTL function will convert chronic GVHD to acute GVHD in DBA → F1 mice. Agents that completely suppress T cell function will block both phenotypes. The model is also useful for examining the effect作者: 2否定 時間: 2025-3-29 01:22 作者: archaeology 時間: 2025-3-29 03:49 作者: BUMP 時間: 2025-3-29 09:23
https://doi.org/10.1007/978-3-8274-2223-1rkers of disease activity. This chapter presents protocols that have been developed for the study of fibrocytes obtained from human circulation and tissues. Protocols for the quantification of fibrocytes in murine models also are described, along with discussion of common technical challenges. It is作者: Fermentation 時間: 2025-3-29 13:10 作者: 使高興 時間: 2025-3-29 17:05
Einteilung und Entstehung der Gesteinease indicators such as DTH, in vitro proliferation, and immunohistochemistry are provided. TMEV-IDD is a useful model for understanding the possible viral etiology of MS. This section provides detailed information on the preparation of viral stocks and subsequent intracerebral infection of mice. Add作者: Irascible 時間: 2025-3-29 20:52
Pathogenesis and Spectrum of Autoimmunity,ors..One of the basic functions of the immune system is to specifically recognize and eliminate foreign antigens and, thus, protect integrity of the host. Through rearrangements and somatic mutations of various gene segments encoding T and B cell receptors and antibody molecules, the immune system a作者: 預防注射 時間: 2025-3-30 03:25 作者: 腐蝕 時間: 2025-3-30 04:40 作者: 無法解釋 時間: 2025-3-30 08:31
Assessment of Mitochondrial Dysfunction in Lymphocytes of Patients with Systemic Lupus Erythematosuellular glutathione and ATP. Increased production of nitric oxide has been identified as a cause of MHP and increased mitochondrial biogenesis. Oxidative stress affects signaling through the T cell receptor as well as activity of redox--sensitive caspases. ATP depletion causes diminished activation-作者: pacifist 時間: 2025-3-30 15:14 作者: 托運 時間: 2025-3-30 18:15 作者: 苦笑 時間: 2025-3-31 00:12 作者: 采納 時間: 2025-3-31 03:40 作者: 生來 時間: 2025-3-31 08:01 作者: ULCER 時間: 2025-3-31 12:26
Flow Cytometric Identification of Fibrocytes in Scleroderma Lung Disease,rkers of disease activity. This chapter presents protocols that have been developed for the study of fibrocytes obtained from human circulation and tissues. Protocols for the quantification of fibrocytes in murine models also are described, along with discussion of common technical challenges. It is作者: 橫截,橫斷 時間: 2025-3-31 16:53 作者: fiscal 時間: 2025-3-31 20:25 作者: 分開 時間: 2025-4-1 01:38
Book 2012Latest editionthods in Molecular Biology(tm). series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory..?.??.Through and intuitive, .Autoimmunity: Methods and Protocols, Second Edition. seeks to aid scientists in t作者: 種族被根除 時間: 2025-4-1 04:30 作者: 朋黨派系 時間: 2025-4-1 07:37 作者: Hyaluronic-Acid 時間: 2025-4-1 10:16
978-1-4939-5637-1Springer Science+Business Media New York 2012作者: 認為 時間: 2025-4-1 15:43
https://doi.org/10.1007/978-3-642-41757-3ystem, tolerance mechanisms develop that prevent or inhibit potentially harmful reactivities to self-antigens. Autoreactive B and T cells that are generated during immune responses are eliminated by apoptosis in the thymus, lymph nodes, or peripheral circulation or actively suppressed by regulatory
