標題: Titlebook: Autoimmune Liver Diseases; Perspectives from Ja Hiromasa Ohira Book 2014 Springer Japan 2014 AIH.PBC.autoimmune hepatitis.primary biliary c [打印本頁] 作者: ACORN 時間: 2025-3-21 18:26
書目名稱Autoimmune Liver Diseases影響因子(影響力)
書目名稱Autoimmune Liver Diseases影響因子(影響力)學科排名
書目名稱Autoimmune Liver Diseases網(wǎng)絡公開度
書目名稱Autoimmune Liver Diseases網(wǎng)絡公開度學科排名
書目名稱Autoimmune Liver Diseases被引頻次
書目名稱Autoimmune Liver Diseases被引頻次學科排名
書目名稱Autoimmune Liver Diseases年度引用
書目名稱Autoimmune Liver Diseases年度引用學科排名
書目名稱Autoimmune Liver Diseases讀者反饋
書目名稱Autoimmune Liver Diseases讀者反饋學科排名
作者: 復習 時間: 2025-3-21 22:43 作者: Foam-Cells 時間: 2025-3-22 00:59
Histological Findings of Autoimmune Hepatitisical interaction of lymphocytes and hepatocytes, is noted but is sometimes difficult to evaluate. In addition to classical AIH, showing chronic active hepatitis, some AIH patients show a clinically acute hepatitis-like clinical course. These patients have mostly acute exacerbation from chronic activ作者: MOT 時間: 2025-3-22 08:16 作者: 頂點 時間: 2025-3-22 10:17 作者: Wallow 時間: 2025-3-22 15:47
Management Strategies for Autoimmune Hepatitis Treatment Nonrespondersfects. Therefore, an investigation of the pathological conditions associated with this disease, such as severity, complications, and age, as well as the use of immunosuppressant, AZA therapy, and other treatments, is warranted for treatment-resistant cases. The applicability of liver transplantation作者: 索賠 時間: 2025-3-22 20:06
Nonalcoholic Steatohepatitis-Autoimmune Hepatitis Overlapd AIH are wide and thus, clinical findings of both NASH and AIH can coexist. NASH-AIH overlap should be clinically treated as coexisting AIH and NASH regardless of whether or not each is an independent disease entity.作者: 防銹 時間: 2025-3-22 23:53 作者: Gastric 時間: 2025-3-23 03:46
Animal Models for Primary Biliary Cirrhosisd from exogenous costimulatory immunoreceptor-conjugated immunoglobulin, i.e., cytotoxic T lymphocyte antigen 4 (CTLA-4)-Ig, was quite efficient to improve developed cholangitis in 2OA-BSA-immunized mice. These results highlighted the pivotal roles of T cells, especially CD8. T cells, the regulatory作者: 傀儡 時間: 2025-3-23 07:44
Epidemiology and Natural History in Japan by liver disease has decreased. The 5-year survival rates were 97.9 and 80.3?%, the 10-year survival rate 93.7 and 66.7?%, and the 20-year survival rate 84.2 and 52.1?%, respectively, showing significant differences among the groups (.?
作者: forbid 時間: 2025-3-23 11:36
New Histological Staging and Grading System for Primary Biliary Cirrhosise degree of both chronic cholangitis activity (CA) and hepatitic activity (HA) for grading disease activity were also proposed. Our recent study demonstrated that this new system provides more information, which is consistent with clinical laboratory data and a better reflection of the prognosis of 作者: 我不怕犧牲 時間: 2025-3-23 17:05
Autoantibodies in Primary Biliary Cirrhosisd use of particular ANAs in conjunction with an AMA should be advantageous for accurate and precise diagnoses and even for disease outcomes. The PBC landscape has been steadily changing with the progress in autoantibody research.作者: FLASK 時間: 2025-3-23 20:56
Book 2014cluded in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the d作者: 鄙視讀作 時間: 2025-3-23 23:03
Anwendung und praktische Validierung,, which participate in the maintenance of tolerance. Additionally, the interaction among several kinds of immune cells (dendritic cell, T cell, B cell, natural killer cell, and natural killer T cell), hepatocytes, and non-parenchymal cells (Kupffer cell, hepatic stellate cell, and sinusoidal endothe作者: 健忘癥 時間: 2025-3-24 02:49
Gestaltung von FahrzeuggetriebenH progresses, the CXCR3–CXCL9 axis is crucial for the migration of T helper 1 cells and effector CD8. T cells into the liver, causing fatal damage. Dendritic-cell-derived IL-18 is critical for differentiation of CXCR3-expressing Th1 cells and CD8. effector T cells in the spleen. In addition, we have作者: cogent 時間: 2025-3-24 08:19
Gestaltung von Finanzierungsbeziehungenical interaction of lymphocytes and hepatocytes, is noted but is sometimes difficult to evaluate. In addition to classical AIH, showing chronic active hepatitis, some AIH patients show a clinically acute hepatitis-like clinical course. These patients have mostly acute exacerbation from chronic activ作者: interlude 時間: 2025-3-24 14:44
Gestaltung von Funktionskostenrechnungen an acute presentation of AIH respond well to corticosteroid therapy; however, the prognosis of AIH patients worsens with progression to acute liver failure. Liver transplantation is a possible treatment option for patients with acute liver failure who do not respond to corticosteroid therapy.作者: 粗俗人 時間: 2025-3-24 16:48
Gestaltung von Funktionskostenrechnungenl dose is generally maintained for 2–4 weeks. Thereafter, PSL dose is carefully tapered down to the maintenance dose (5–10?mg/day). To avoid early relapse, PSL dose should be maintained at 0.2?mg/kg/day or more until the normalization of serum transaminase levels. For patients who show treatment fai作者: transient-pain 時間: 2025-3-24 21:06 作者: 表否定 時間: 2025-3-25 02:45 作者: diabetes 時間: 2025-3-25 03:49
https://doi.org/10.1007/978-3-658-19289-1FSF15) and B cell differentiation into plasma cells (IL7R, CXCR5, SPIB, IKZF3, and POU2AF1) between individuals of European descent and Japanese individuals. Most of these disease susceptibility genes are not specific for PBC; they are shared with various other autoimmune diseases. Further studies o作者: infinite 時間: 2025-3-25 11:00 作者: epinephrine 時間: 2025-3-25 13:29
,Typische Gr??e von Konzernzentralen, by liver disease has decreased. The 5-year survival rates were 97.9 and 80.3?%, the 10-year survival rate 93.7 and 66.7?%, and the 20-year survival rate 84.2 and 52.1?%, respectively, showing significant differences among the groups (.?
作者: 脆弱么 時間: 2025-3-25 16:27
Notwendigkeit und Aussagegehalt der Studie,e degree of both chronic cholangitis activity (CA) and hepatitic activity (HA) for grading disease activity were also proposed. Our recent study demonstrated that this new system provides more information, which is consistent with clinical laboratory data and a better reflection of the prognosis of 作者: Flounder 時間: 2025-3-25 20:20
https://doi.org/10.1007/978-3-322-99713-5d use of particular ANAs in conjunction with an AMA should be advantageous for accurate and precise diagnoses and even for disease outcomes. The PBC landscape has been steadily changing with the progress in autoantibody research.作者: 藕床生厭倦 時間: 2025-3-26 03:59
lso recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the d978-4-431-56171-2978-4-431-54789-1作者: 手榴彈 時間: 2025-3-26 08:13
Book 2014e liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, 作者: 陰謀 時間: 2025-3-26 09:39 作者: 明智的人 時間: 2025-3-26 13:55 作者: 妨礙議事 時間: 2025-3-26 17:29
Diagnosis of Autoimmune Hepatitis Because a recently conducted nationwide survey on AIH in Japan has revealed clinical pathological conditions that are different from those previously known, new diagnostic criteria have been issued. This section reviews the diagnosis of AIH mainly on the basis of the new Japanese diagnostic criteria.作者: Judicious 時間: 2025-3-27 00:22
Gestaltung von Fahrzeuggetriebennosuppressive therapy is successful. Multiple relapses have been shown to contribute to a poor outcome and development of hepatocellular carcinoma (HCC). Therefore, it is considered essential to minimize relapses by continuing immunosuppressive therapy indefinitely in patients with AIH.作者: 賭博 時間: 2025-3-27 02:11
Epidemiology and Natural History in Japannosuppressive therapy is successful. Multiple relapses have been shown to contribute to a poor outcome and development of hepatocellular carcinoma (HCC). Therefore, it is considered essential to minimize relapses by continuing immunosuppressive therapy indefinitely in patients with AIH.作者: Ganglion-Cyst 時間: 2025-3-27 09:21
https://doi.org/10.1007/978-3-322-97741-0revalence is considered to be similar in Japan..The diagnosis of ASC is similar to that of the overlap of AIH and PSC in adults, but acute-onset AIH is more frequent and can be difficult to distinguish from ASC, making endoscopic retrograde cholangiopancreatography (ERCP) and other forms of cholangiography necessary.作者: ANNUL 時間: 2025-3-27 10:08 作者: 統(tǒng)治人類 時間: 2025-3-27 13:36 作者: 黑豹 時間: 2025-3-27 20:35
Pediatric Autoimmune Hepatitisrevalence is considered to be similar in Japan..The diagnosis of ASC is similar to that of the overlap of AIH and PSC in adults, but acute-onset AIH is more frequent and can be difficult to distinguish from ASC, making endoscopic retrograde cholangiopancreatography (ERCP) and other forms of cholangiography necessary.作者: 煉油廠 時間: 2025-3-28 00:23 作者: 責任 時間: 2025-3-28 03:35 作者: cavity 時間: 2025-3-28 08:10
https://doi.org/10.1007/978-4-431-54789-1AIH; PBC; autoimmune hepatitis; primary biliary cirrhosis; hepatology作者: 過濾 時間: 2025-3-28 11:52
Hiromasa OhiraBased on Japanese research findings in autoimmune liver diseases.Explains how Japanese patients with autoimmune hepatitis form a unique disease population as a result of their genetic background.Prese作者: CRACK 時間: 2025-3-28 18:27 作者: –scent 時間: 2025-3-28 21:44
Anwendung und praktische Validierung,tiation of the disease can be related to both environmental and genetic factors, and AIH is likely to develop in people with predisposed genetic backgrounds who have been exposed to conducive environmental factors, such as viral infections or drugs. In autoimmune diseases, autoantigens stimulate aut作者: 斥責 時間: 2025-3-29 00:37
Gestaltung von Fahrzeuggetriebennt of AIH. However, those models have lacked the characteristics of human AIH, such as hypergammaglobulinemia and production of circulating autoantibodies. In contrast, we have developed mouse models of spontaneous AIH with hypergammaglobulinemia and ANA production. Immune dysregulation by a concurr作者: 使長胖 時間: 2025-3-29 05:18 作者: 無能力之人 時間: 2025-3-29 09:38
Gestaltung von Finanzierungsbeziehungenc histology of AIH is similar to that of virus-related chronic hepatitis, hepatitic changes are usually prominent in AIH compared with chronic viral hepatitis. Clinicopathological diagnosis of AIH requires exclusion of other causes of liver disease, including hepatitis virus, alcohol, drugs, metabol作者: CANDY 時間: 2025-3-29 15:10 作者: CRUDE 時間: 2025-3-29 19:05 作者: 歡樂東方 時間: 2025-3-29 23:26
Gestaltung von Funktionskostenrechnungenpeated relapses are risk factors for poor outcomes (liver failure, or hepatocellular carcinoma, liver transplantation, death). Patients showing abnormalities of serum ALT levels (>30?IU/L), which indicate the presence of intrahepatic inflammation, should be treated with immunosuppressive treatment, 作者: 人造 時間: 2025-3-30 00:35 作者: eulogize 時間: 2025-3-30 04:56 作者: 合并 時間: 2025-3-30 09:17 作者: 拍翅 時間: 2025-3-30 15:01 作者: Arthritis 時間: 2025-3-30 20:18
https://doi.org/10.1007/978-3-662-11868-9hondrial inner membrane..The involvement of autoimmunity is considered due to the presence of both autoreactive CD4-positive T cells and CD8-positive T cells recognizing PDC-E2. Autoreactive NK cells are also involved in bile duct damage and in addition to acquired immunity, abnormalities in innate 作者: Mortal 時間: 2025-3-30 21:03 作者: gain631 時間: 2025-3-31 03:45 作者: GLOSS 時間: 2025-3-31 08:03
,Typische Gr??e von Konzernzentralen,Group in Japan supported by the Health Labour Sciences Research Grant. The subjects were 8,509 patients with PBC diagnosed and followed up between January 1, 1968 and December 31, 2011 at 520 hospitals and institutions throughout the country. We investigated the epidemiological trends and long-term 作者: 確保 時間: 2025-3-31 11:19
Notwendigkeit und Aussagegehalt der Studie,these classical staging systems, PBC livers were classified into four stages on the basis of a single characteristic histological feature of PBC such as chronic nonsuppurative destructive cholangitis and bile ductular proliferation. It is well known that these histological features are heterogeneous作者: nostrum 時間: 2025-3-31 15:06
https://doi.org/10.1007/978-3-322-99713-5in the development of accurate and sensitive solid-phase assays for the detection of antimitochondrial antibody (AMA), a small but substantial number of patients are still regarded as having AMA-negative PBC. PBC-specific antinuclear antibodies (ANAs) are thus valuable as complementary serological m作者: cardiovascular 時間: 2025-3-31 18:19 作者: 過時 時間: 2025-3-31 23:08
Models of Autoimmune Hepatitisnt of AIH. However, those models have lacked the characteristics of human AIH, such as hypergammaglobulinemia and production of circulating autoantibodies. In contrast, we have developed mouse models of spontaneous AIH with hypergammaglobulinemia and ANA production. Immune dysregulation by a concurr作者: LATER 時間: 2025-4-1 02:38 作者: Talkative 時間: 2025-4-1 06:09 作者: Solace 時間: 2025-4-1 13:57
Diagnosis of Autoimmune Hepatitisdy known hepatic disorders. As strategies to establish the diagnosis, various diagnostic criteria, guidelines, and scoring systems have been proposed. Because a recently conducted nationwide survey on AIH in Japan has revealed clinical pathological conditions that are different from those previously作者: 跳動 時間: 2025-4-1 17:17 作者: Crater 時間: 2025-4-1 22:07
