標(biāo)題: Titlebook: Attempts to Understand Metastasis Formation I; Metastasis-Related M Ursula Günthert,Walter Birchmeier Book 1996 The Editor(s) (if applicabl [打印本頁] 作者: Pierce 時(shí)間: 2025-3-21 16:15
書目名稱Attempts to Understand Metastasis Formation I影響因子(影響力)
書目名稱Attempts to Understand Metastasis Formation I影響因子(影響力)學(xué)科排名
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書目名稱Attempts to Understand Metastasis Formation I被引頻次
書目名稱Attempts to Understand Metastasis Formation I被引頻次學(xué)科排名
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書目名稱Attempts to Understand Metastasis Formation I年度引用學(xué)科排名
書目名稱Attempts to Understand Metastasis Formation I讀者反饋
書目名稱Attempts to Understand Metastasis Formation I讀者反饋學(xué)科排名
作者: terazosin 時(shí)間: 2025-3-21 21:32
Membrane Type-Matrix Metalloproteinase and Tumor Invasion,on itself does not mean immediate use of the enzymes for tumor invasion or for the remodeling of the extracellular matrix (ECM), processes associated with tumor growth. MMPs are produced and secreted as zymogens (pro-MMPs) that need proteolytic activation for the enzymes to function (. 1991; . et al作者: TAIN 時(shí)間: 2025-3-22 00:54
Plasminogen Activators and Angiogenesis,development, would healing and tumor growth. Angiogenesis requires a strict temporal modulation of opposing cell functions: cell proliferation and migration, and extracellular matrix (ECM) degradation in the initial steps; arrest of cell proliferation and migration, ECM deposition and morphogenesis 作者: follicular-unit 時(shí)間: 2025-3-22 06:19 作者: 范例 時(shí)間: 2025-3-22 11:51 作者: Astigmatism 時(shí)間: 2025-3-22 13:16 作者: 運(yùn)氣 時(shí)間: 2025-3-22 18:00
MUC18: A Cell Adhesion Molecule with a Potential Role in Tumor Growth and Tumor Cell Dissemination,ew properties (. and . 1982; . and . 1992). The identification of molecules which are newly expressed, altered or lost during this process can lead to an understanding of the molecular basis of tumor progression and metastasis formation and can also lead to the development of diagnostic and therapeu作者: 使更活躍 時(shí)間: 2025-3-23 00:50 作者: 陳腐的人 時(shí)間: 2025-3-23 02:27
The E-cadherin/Catenin Complex in Invasion and Metastasis,ut penetrate into the surrounding normal tissues. On their way to lymph or blood vessels they create a path of destruction. This invasive behavior eventually gives access to the circulation, and opens a gate to metastatic dissemination(. et al.; . and . 1982; . et al. 1993).作者: CROW 時(shí)間: 2025-3-23 09:16 作者: 鄙視讀作 時(shí)間: 2025-3-23 11:49
Model Systems of Carcinoma Cell Dispersion,n the mouse skin system, for example, the loss of epithelial differentiation is accompanied by the appearance of malignant properties. In this well-studied system, chemical carcinogenesis generates multiple benign tumors, a proportion of which develop to form squamous cell carcinomas and, in extreme作者: majestic 時(shí)間: 2025-3-23 17:41
,Involvement of α6 and αv Integrins in Metastasis,y cels of the primary tumor is involved in this event, for example, E-cadherin in carcinomas (Frixen et al. 1991) and α4 integrin in melanomas (Qian et al. 1994). Migrating metastatic cells enter the blood vasculature or the lymphatics through which they are transported to peripherical organs. In th作者: 向外供接觸 時(shí)間: 2025-3-23 18:50 作者: glamor 時(shí)間: 2025-3-23 23:26 作者: Confidential 時(shí)間: 2025-3-24 03:47 作者: canonical 時(shí)間: 2025-3-24 07:12
CD44 in Maligant Disorders,n embryogenesis, and inflammatory reactions. Possible explanations for the supposedly multipurpose nature of CD44 include the existence of an enormous number of isoforms and/or the potential likelihood that the role of CD44 in all these diverse processes is not as manifold as it sounds, because we s作者: fiscal 時(shí)間: 2025-3-24 14:43
B2SAT: A Bare-Metal Reduction of?B to?SATned within a defined space, most neoplasms could be removed and subsequently cured with the surgeon’s scalpel. However, this is not the case within the scope of cancer biology. Some neoplasms are highly metastatic (melanoma), while others are rarely metastatic (brain tumors), but given enough time a作者: 漂泊 時(shí)間: 2025-3-24 15:28
Stochastic Games for?User Journeyson itself does not mean immediate use of the enzymes for tumor invasion or for the remodeling of the extracellular matrix (ECM), processes associated with tumor growth. MMPs are produced and secreted as zymogens (pro-MMPs) that need proteolytic activation for the enzymes to function (. 1991; . et al作者: 細(xì)胞學(xué) 時(shí)間: 2025-3-24 21:27
Xiang He,Bohan Li,Mengyu Zhao,Shaowei Caidevelopment, would healing and tumor growth. Angiogenesis requires a strict temporal modulation of opposing cell functions: cell proliferation and migration, and extracellular matrix (ECM) degradation in the initial steps; arrest of cell proliferation and migration, ECM deposition and morphogenesis 作者: 禮節(jié) 時(shí)間: 2025-3-25 00:10
Xiang He,Bohan Li,Mengyu Zhao,Shaowei Cai of its expression at the mRNA level in normal but not in tumor-derived mammary epithelial cells (. et al. 1994). The cloned and sequenced cDNA consists of 2584 nucleotides encoding a 42 kDa peptide with the overall structure of a serpin. Maspin has been localized to chromosome 18q21.3-q23 (. et al.作者: majestic 時(shí)間: 2025-3-25 06:15
Arnd Hartmanns,Bram Kohlen,Peter Lammichand assemble the components of the ECM whereas the ECM stabilizes the physical structure of tissues and also regulates the behavior of cells (. 1988, . and . 1993). Transformed cells can alter the composition and structural integrity of adjacent matrix promoting tumor progression. Enzymes produced b作者: semiskilled 時(shí)間: 2025-3-25 11:33
A Local Search Algorithm for?MaxSMT(LIA)cell-cell and cell-matrix contacts are likely to influence both normal responses (e.g. wound healing) and abnormal processes (e.g. malignant transformation). The glycoprotein SPARC (secreted protein, acidic and rich in cysteine), also termed osteonectin, BM-40, and 43 K protein, has been classified,作者: V切開 時(shí)間: 2025-3-25 14:59
Loes Kruger,Sebastian Junges,Jurriaan Rotew properties (. and . 1982; . and . 1992). The identification of molecules which are newly expressed, altered or lost during this process can lead to an understanding of the molecular basis of tumor progression and metastasis formation and can also lead to the development of diagnostic and therapeu作者: phytochemicals 時(shí)間: 2025-3-25 16:07
Soaibuzzaman,Jan Oliver Ringertrly events include a loosening of cell-cycle control and disabling of checkpoints and failsafe mechanisms such as cell-cell constraints on proliferation and motility (. et al. 1992; . and . 1990). Successfully metastatic cells arising from this population display an altered repertoire of cell adhesi作者: GRIEF 時(shí)間: 2025-3-25 22:28
Stefan Hallerstede,John Hatcliff,Robbyut penetrate into the surrounding normal tissues. On their way to lymph or blood vessels they create a path of destruction. This invasive behavior eventually gives access to the circulation, and opens a gate to metastatic dissemination(. et al.; . and . 1982; . et al. 1993).作者: APEX 時(shí)間: 2025-3-26 02:36 作者: 入會(huì) 時(shí)間: 2025-3-26 06:32
Soaibuzzaman,Jan Oliver Ringertn the mouse skin system, for example, the loss of epithelial differentiation is accompanied by the appearance of malignant properties. In this well-studied system, chemical carcinogenesis generates multiple benign tumors, a proportion of which develop to form squamous cell carcinomas and, in extreme作者: Headstrong 時(shí)間: 2025-3-26 09:17 作者: 態(tài)度暖昧 時(shí)間: 2025-3-26 16:32 作者: 墻壁 時(shí)間: 2025-3-26 16:54
Eduard Baranov,Axel Legay,Martin Viviane morphogenesis and organogenesis and are involved in the maintenance of organ structures (. 1990;. 1992a; . and . 1993; . et al. 1993). Adhesion molecules are of the utmost importance for most functional activities of the immune system (. 1990; . and . 1991; . et al. 1992; . 1992; . 1992; . et al. 作者: phlegm 時(shí)間: 2025-3-26 22:56
Logika: The Sireum Verification Frameworkis of the metastatic process, however, which is the chief contributor to cancer patient morbidity, has met with various obstacles due to its complexity. As a result, we still know very little about how cancer cells spread.It is generally assumed that cancer cells randomly diversify during tumor prog作者: Triglyceride 時(shí)間: 2025-3-27 04:53 作者: 流動(dòng)才波動(dòng) 時(shí)間: 2025-3-27 07:30
Current Topics in Microbiology and Immunologyhttp://image.papertrans.cn/b/image/164879.jpg作者: blithe 時(shí)間: 2025-3-27 10:31
The E-cadherin/Catenin Complex in Invasion and Metastasis,ut penetrate into the surrounding normal tissues. On their way to lymph or blood vessels they create a path of destruction. This invasive behavior eventually gives access to the circulation, and opens a gate to metastatic dissemination(. et al.; . and . 1982; . et al. 1993).作者: overbearing 時(shí)間: 2025-3-27 15:02
Attempts to Understand Metastasis Formation I978-3-642-61107-0Series ISSN 0070-217X Series E-ISSN 2196-9965 作者: inclusive 時(shí)間: 2025-3-27 20:09
Stefan Hallerstede,John Hatcliff,Robbyut penetrate into the surrounding normal tissues. On their way to lymph or blood vessels they create a path of destruction. This invasive behavior eventually gives access to the circulation, and opens a gate to metastatic dissemination(. et al.; . and . 1982; . et al. 1993).作者: 無關(guān)緊要 時(shí)間: 2025-3-27 21:59
https://doi.org/10.1007/978-3-642-61107-0activation; biology; cancer; cell; cytokine; gene; gene therapy; growth; growth factor; immunotherapy; membran作者: 防銹 時(shí)間: 2025-3-28 04:47
978-3-642-64697-3The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE作者: 嚴(yán)厲批評(píng) 時(shí)間: 2025-3-28 10:17
Book 1996ipke, Nicolson, Folkman and others). In the 1980s and 1990s, several of the molecules involved were identified and their network interactions elucidated. These three volumes of Current Topics in Microbiology and Immuno- logy compile the most recent developments on these meta- stasis-related molecule作者: 隱語 時(shí)間: 2025-3-28 10:53
Xiang He,Bohan Li,Mengyu Zhao,Shaowei Caiar ECM and endothelial cell invasion into the tissue to be vascularized. A number of studies have shown that, among the proteinases involved in angiogenesis, components of the plasminogen activator (PA)-plasmin system play a central role in endothelial cell migration and invasion.作者: obtuse 時(shí)間: 2025-3-28 17:05
Arnd Hartmanns,Bram Kohlen,Peter Lammichplex control mechanisms, is required in malignancy. The functional role of the enzymatic degradation of ECM by tumor cells has been thought to be the dissolution of occluding matrix, thus enabling the cells to invade into the interstitial matrix of the mesenchyme at the site of a primary tumor, to c作者: 苦笑 時(shí)間: 2025-3-28 19:44
Soaibuzzaman,Jan Oliver Ringert lungs has often been attributed solely to mechanical entrapment of tumor cell emboli. However, this theory does not explain the early observation that certain. tumor cell types prefer to metastasize to specific target organs. This behaviour was first noticed by Stephen . in 1889. He observed that b作者: 定點(diǎn) 時(shí)間: 2025-3-29 01:59 作者: Explosive 時(shí)間: 2025-3-29 03:13
Dalay Almeida,Florian Jamain,Thierry Lecomteoteins that are capable of binding to laminin (MERCURIO1990). Laminin receptors include several integrins (ABELDAand BUCK 1990), as well as a variety of nonintegrin proteins (MERCURIOI 990), including a 67-kDa high-affinity laminin receptor.作者: 食料 時(shí)間: 2025-3-29 08:45
Eduard Baranov,Axel Legay,Martin Vivianthe latter group including CD44 (. and . 1988; . et al. 1988; . and . 1990; . and . 1990; . 1990; . 1990; . and . 1992; . and .-. 1993; . et al. 1993; . and . 1994; . and . 1994;). Especially integrins, the lg superfamily, and HCAM consist of a multitude of members, a number which is increased by co作者: 流動(dòng)才波動(dòng) 時(shí)間: 2025-3-29 11:31 作者: crumble 時(shí)間: 2025-3-29 19:36
Plasminogen Activators and Angiogenesis,ar ECM and endothelial cell invasion into the tissue to be vascularized. A number of studies have shown that, among the proteinases involved in angiogenesis, components of the plasminogen activator (PA)-plasmin system play a central role in endothelial cell migration and invasion.作者: myopia 時(shí)間: 2025-3-29 20:29
Different Roles for Plasminogen Activators and Metalloproteinases in Melanoma Metastasis,plex control mechanisms, is required in malignancy. The functional role of the enzymatic degradation of ECM by tumor cells has been thought to be the dissolution of occluding matrix, thus enabling the cells to invade into the interstitial matrix of the mesenchyme at the site of a primary tumor, to c作者: corpuscle 時(shí)間: 2025-3-30 02:29
Lu-ECAM-1 and DPP IV in Lung Metastasis, lungs has often been attributed solely to mechanical entrapment of tumor cell emboli. However, this theory does not explain the early observation that certain. tumor cell types prefer to metastasize to specific target organs. This behaviour was first noticed by Stephen . in 1889. He observed that b作者: verdict 時(shí)間: 2025-3-30 07:50
Model Systems of Carcinoma Cell Dispersion,ncluding colon and breast. Whether or not these phenotypic alterations can be regarded as authentic epithelium-to-mesenchyme transitions (EMTs), similar to those observed during embryogenesis, remains to be clarified. Nevertheless, since the maintenance of epithelial cell differentiation acts as a s作者: 證明無罪 時(shí)間: 2025-3-30 08:48
The 67-kDa Laminin Receptor and Tumor Progression,oteins that are capable of binding to laminin (MERCURIO1990). Laminin receptors include several integrins (ABELDAand BUCK 1990), as well as a variety of nonintegrin proteins (MERCURIOI 990), including a 67-kDa high-affinity laminin receptor.作者: FOLD 時(shí)間: 2025-3-30 14:51 作者: Phagocytes 時(shí)間: 2025-3-30 18:39
The CD44 Proteins in Embryonic Development and in Cancer,must then move towards lymphatic and blood vessels, enter these vessels, and survive during their transport within the fluid medium.It must also colonize draining lymphatic tissue and further disseminate through efferent lymphatics into the blood stream, extravasate from blood vessels and, finally, 作者: 干旱 時(shí)間: 2025-3-30 22:29 作者: 泥瓦匠 時(shí)間: 2025-3-31 03:28
B2SAT: A Bare-Metal Reduction of?B to?SATisseminate and form viable metastatic colonies as well as discuss potential therapies for metastatic disease. This chapter will address the role of the matrix metalloproteinases (MMPs) and their inhibitors in the process of tumor progression, invasion, and metastasis.作者: ambivalence 時(shí)間: 2025-3-31 07:07 作者: INERT 時(shí)間: 2025-3-31 11:45 作者: 約會(huì) 時(shí)間: 2025-3-31 13:52 作者: jungle 時(shí)間: 2025-3-31 20:55
A Local Search Algorithm for?MaxSMT(LIA) migration implicate SPARC as a regulatory protein in both wound healing and cancer. The purpose of this chapter is to review the properties of this protein and the functional implications for SPARC in neoplasia and tissue repair.
