標(biāo)題: Titlebook: Aspartic Proteinases; Structure, Function, Kenji Takahashi Book 1995 The Editor(s) (if applicable) and The Author(s), under exclusive licen [打印本頁] 作者: magnify 時間: 2025-3-21 20:09
書目名稱Aspartic Proteinases影響因子(影響力)
書目名稱Aspartic Proteinases影響因子(影響力)學(xué)科排名
書目名稱Aspartic Proteinases網(wǎng)絡(luò)公開度
書目名稱Aspartic Proteinases網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Aspartic Proteinases被引頻次
書目名稱Aspartic Proteinases被引頻次學(xué)科排名
書目名稱Aspartic Proteinases年度引用
書目名稱Aspartic Proteinases年度引用學(xué)科排名
書目名稱Aspartic Proteinases讀者反饋
書目名稱Aspartic Proteinases讀者反饋學(xué)科排名
作者: grandiose 時間: 2025-3-21 23:06
The Molecular Structure of Human Progastricsin and its Comparison with that of Porcine Pepsinogenocatalytically at pH < 5.0 (1). The human gastric juice has two major groups of aspartic proteinases, the pepsins (EC3.4.23.1) and the gastricsins (EC3.4.23.3). Progastricsin or pepsinogen C (PGC) is converted to gastricsin by removal of the 43 amino-terminal residues of the prosegment. The resultin作者: foppish 時間: 2025-3-22 02:56 作者: 希望 時間: 2025-3-22 05:52
Rearranging Pepsinogen and Pepsin by Protein Engineeringilobal structures. The three-dimensional structures of the N- and C-terminal lobes are homologous. It has been hypothesized that the origin of this internal similarity in eukaryotic aspartic proteases is derived from an evolutionary process of gene duplication and fusion (1). A primordial form of as作者: GREEN 時間: 2025-3-22 11:05 作者: AWL 時間: 2025-3-22 15:45 作者: 迎合 時間: 2025-3-22 21:00
Transcription Regulation of Human and Porcine Pepsinogen Ainical point of view pepsinogen gene regulation is interesting. Pepsinogen, activated by acid to pepsin, is one of the aggressive factors in the stomach that play a role in peptic ulcer disease (1). A dominantly inherited high pepsinogen A (PGA) output is associated with duodenal ulcer (2). On the o作者: 苦惱 時間: 2025-3-22 23:17
A Comparative Study on Amino Acid Sequences of Three Major Isoforms of Human Pepsin Ances has hindered progress to any clear explanation for these differences. The sequence data available has been based mainly on N-terminal amino-acid and cDNA analysis of human pepsinogens [2, 4, 5]. We have therefore undertaken further more detailed amino-acid sequence studies of isolated human pep作者: 拖債 時間: 2025-3-23 05:04 作者: 束以馬具 時間: 2025-3-23 06:37
Evidence for Electrostatic Interactions in the S2 Subsite of Porcine PepsinPepsin, a member of this family involved in the digestion of proteins in the stomach, has been a valuable model system for investigation into enzymatic specificity. The active site cleft of porcine pepsin is made of distinct subsites S.-S.’ (I. Schecter and A. Berger, 1967, B. B. R. C. .: 157) all o作者: acclimate 時間: 2025-3-23 13:30 作者: 漸強 時間: 2025-3-23 15:08 作者: GROVE 時間: 2025-3-23 21:24 作者: 過于平凡 時間: 2025-3-24 01:24
Effects of Omeprazole, a Proton Pump Inhibitor, on Pepsinogen-Producing Cells, with Special Referencrietal cells. However, its effects on pepsinogen-producing cells have not been investigated in detail and results of previous relevant studies on pepsinogen secretion are conflicting. Gastric mucosal cells proliferate and differentiate under an acidic environment in the gastric lumen. Thus, it is pr作者: Optimum 時間: 2025-3-24 04:02 作者: keloid 時間: 2025-3-24 06:36
Serum Pepsinogen Values as Possible Markers for Evaluating the Possibility of Peptic Ulcer Recurrencrecurrence is still a difficult problem. Various maintenance therapies have been set up and tried. But there has been almost no indicator to select a proper therapy for each case. Thus, a marker for predicting ulcer recurrence has been long desired. Serum pepsinogen (PG) values, PG I originating fro作者: 財主 時間: 2025-3-24 12:50
The Clinical Application of the Serum Pepsinogen I And II Levels as a Mass Screening Method for Gastto the early detection of the cancer through mass screening programs throughout the country. In most workplaces in Japan, an indirect X-ray examination, using 10 cm square film, is the conventional first screening step, after which those suspected of having some abnormalities in the gastric mucosa a作者: Corral 時間: 2025-3-24 17:01 作者: Offensive 時間: 2025-3-24 19:25
Two Cases of Early Colorectal Cancer Associated with Gastric Adenoma Detected by Serum Pepsinogen Sctrophic gastritis is now established (1). Since a considerable number of gastric cancer develop in gastric mucosa affected by severe and extensive atrophic gastritis, it is considered as a precancerous condition that leads to the development of gastric cancer (2). Indeed, the prevalence rates of atr作者: AGGER 時間: 2025-3-24 23:57
Seminal Progastricsinon to pH 2. As the enzyme was purified, it became evident that it was in fact equivalent to the minor gastric enzyme originally named as progastricsin (EC 3.4.23.3) [2–6].This report provides a short review on the similarities and differences between human gastric and seminal progastricsin, and the possible function of the seminal progastricsin.作者: 團結(jié) 時間: 2025-3-25 04:14 作者: 漂浮 時間: 2025-3-25 10:58 作者: Concrete 時間: 2025-3-25 13:56 作者: 古董 時間: 2025-3-25 16:53
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/b/image/163035.jpg作者: conformity 時間: 2025-3-25 23:56
Aspartic Proteinases978-1-4615-1871-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 優(yōu)雅 時間: 2025-3-26 02:23
https://doi.org/10.1007/978-3-642-70036-1on to pH 2. As the enzyme was purified, it became evident that it was in fact equivalent to the minor gastric enzyme originally named as progastricsin (EC 3.4.23.3) [2–6].This report provides a short review on the similarities and differences between human gastric and seminal progastricsin, and the possible function of the seminal progastricsin.作者: FIG 時間: 2025-3-26 07:18
Wirtschaftswissenschaftliche Beitr?genogenesis in higher vertebrates [1, 2]. The morphological and the functional differentiation of an organ necessarily involves the local expression or suppression of sets of genes in the cells constituting the organ.作者: 悲觀 時間: 2025-3-26 11:36
Local Visions for a Global Future,me, an increasingly rapid stream of structural information has issued from the crystallography groups [2]. At this point it is clear that members of this family are closely related structurally, with a central core composed of two domains, each of which has a two-layered β-sheet arrangement (see Fig作者: 不足的東西 時間: 2025-3-26 12:48
https://doi.org/10.1007/978-3-319-78837-1ocatalytically at pH < 5.0 (1). The human gastric juice has two major groups of aspartic proteinases, the pepsins (EC3.4.23.1) and the gastricsins (EC3.4.23.3). Progastricsin or pepsinogen C (PGC) is converted to gastricsin by removal of the 43 amino-terminal residues of the prosegment. The resultin作者: glucagon 時間: 2025-3-26 19:27 作者: 窩轉(zhuǎn)脊椎動物 時間: 2025-3-26 21:56 作者: 迫擊炮 時間: 2025-3-27 01:42
https://doi.org/10.1007/978-3-319-78837-1re the term enzyme was introduced, and in the early days of biochemistry pepsin A was used as a model enzyme in numerous investigations. The minor proteolytic components of the gastric juice have received much less attention. Pepsin B (EC 3.4.23.2) and gastricsin (EC 3.4.23.3) were isolated by Ryle 作者: Gene408 時間: 2025-3-27 08:42
https://doi.org/10.1007/978-88-470-1848-8er acidic conditions. It is classified into three major types, that is, pepsinogen A, pepsinogen C (or progastricsin), and prochymosin (or neonatal pepsinogen). Further, pepsinogens, especially pepsinogens A, are often composed of several isozymogens. So far, a number of pepsinogens were purified fr作者: mydriatic 時間: 2025-3-27 12:42
https://doi.org/10.1007/978-88-470-1848-8inical point of view pepsinogen gene regulation is interesting. Pepsinogen, activated by acid to pepsin, is one of the aggressive factors in the stomach that play a role in peptic ulcer disease (1). A dominantly inherited high pepsinogen A (PGA) output is associated with duodenal ulcer (2). On the o作者: 代替 時間: 2025-3-27 15:12 作者: 歪曲道理 時間: 2025-3-27 20:04
https://doi.org/10.1007/978-88-470-0678-2ally measured to within 0.01% of the values calculated from the primary sequences. The aspartic proteinases obtained from gastric secretions, however, have an insufficient number of basic amino acids to be analysed in this way, but should be well suited to negative ion analysis because they contain 作者: Canopy 時間: 2025-3-27 23:43 作者: acetylcholine 時間: 2025-3-28 04:08
Die Instrumente der Fiskalpolitikization, determination and comparative analysis of three-dimensional structures, rule-based design, site-directed mutagenesis and expression of the mutants. Knowledge of the tertiary structure of proteins and the use of molecular modelling techniques provide a powerful approach for the design of nov作者: affinity 時間: 2025-3-28 08:58 作者: 搖晃 時間: 2025-3-28 12:22 作者: 獨裁政府 時間: 2025-3-28 17:44
https://doi.org/10.1007/978-3-642-51533-0rietal cells. However, its effects on pepsinogen-producing cells have not been investigated in detail and results of previous relevant studies on pepsinogen secretion are conflicting. Gastric mucosal cells proliferate and differentiate under an acidic environment in the gastric lumen. Thus, it is pr作者: 我不明白 時間: 2025-3-28 20:40 作者: 背帶 時間: 2025-3-29 02:52 作者: patella 時間: 2025-3-29 04:08 作者: SMART 時間: 2025-3-29 08:22
The Origin of the ROK Nuclear Program,nues to be focused on the early detection of the cancer through mass screening programs throughout the country. In most workplaces, an indirect barium x-ray examination combined with endoscopic inspection has been the standard screening method used in Japan. However, this method has certain drawback作者: 燒瓶 時間: 2025-3-29 12:08 作者: CLAIM 時間: 2025-3-29 16:22
Book 1995stry, Kawashima- cho, Gifu Prefecture, Japan, about 15 miles northwest of Nagoya City. About 100 scientists attended the conference, including 52 from 14 countries outside Japan, and 32 papers were presented by invited speakers, and 58 papers as posters. The purpose of this conference was to present作者: 標(biāo)準 時間: 2025-3-29 22:04 作者: 冒號 時間: 2025-3-30 00:19
https://doi.org/10.1007/978-88-470-1848-8om various sources, characterized and sequenced at the protein level and/or DNA level. Thus the complete amino acid sequences of mammalian pepsinogens are known for human (1), monkey (2), porcine (3–6), and rabbit (7) pepsinogens A, human (8), monkey (9), rat (10) and guinea pig (11) pepsinogens C, and bovine prochymosin (12).作者: 調(diào)情 時間: 2025-3-30 05:54 作者: exhilaration 時間: 2025-3-30 11:48 作者: Fretful 時間: 2025-3-30 12:36
https://doi.org/10.1007/978-3-319-78837-13.4.23.3). Progastricsin or pepsinogen C (PGC) is converted to gastricsin by removal of the 43 amino-terminal residues of the prosegment. The resulting mature gastricsin has 329 amino acid residues. The sequence of human PGC has been determined independently in two laboratories by nucleotide sequencing of the gene (2) and of cDNA clones (3).作者: LOPE 時間: 2025-3-30 18:01
,Processi dinamici nell’atmosfera solare,and cDNA analysis of human pepsinogens [2, 4, 5]. We have therefore undertaken further more detailed amino-acid sequence studies of isolated human pepsin isoforms in order to clarify the structural basis for the differences observed in enzymatic activities.作者: 高談闊論 時間: 2025-3-31 00:20
Comparison of the Active Site Specificity of the Aspartic Proteinases Based on a Systematic Series ohis family are closely related structurally, with a central core composed of two domains, each of which has a two-layered β-sheet arrangement (see Figure 1 for an overall representation of a typical aspartic proteinase).作者: 盤旋 時間: 2025-3-31 03:16 作者: 鉗子 時間: 2025-3-31 08:01
A Comparative Study on Amino Acid Sequences of Three Major Isoforms of Human Pepsin Aand cDNA analysis of human pepsinogens [2, 4, 5]. We have therefore undertaken further more detailed amino-acid sequence studies of isolated human pepsin isoforms in order to clarify the structural basis for the differences observed in enzymatic activities.作者: Genteel 時間: 2025-3-31 11:19
Allgemeine Probleme der Globalsteuerungg chromogenic octapeptide substrates at pH values ranging from 3 to 6. Residue 287 is within the S. region of the active site cleft, and varies widely among the aspartic proteinase family, with Glu, Gln, Met, and Gly occurring in various enzymes.作者: 舞蹈編排 時間: 2025-3-31 16:27
Die Instrumente der Fiskalpolitikglucocorticoids on pepsinogen-producing cells in fully-differentiated stomach mucosa are less clear (4,5). In this study, we examined the effects of hydrocortisone on infant and adult rat stomach mucosa, especially on pepsinogen gene expression and the morphology of pepsinogen-producing cells.作者: Pelago 時間: 2025-3-31 18:57
Evidence for Electrostatic Interactions in the S2 Subsite of Porcine Pepsing chromogenic octapeptide substrates at pH values ranging from 3 to 6. Residue 287 is within the S. region of the active site cleft, and varies widely among the aspartic proteinase family, with Glu, Gln, Met, and Gly occurring in various enzymes.
