標(biāo)題: Titlebook: Apolipoprotein E and Alzheimer’s Disease; A. D. Roses,K. Weisgraber,Y. Christen Conference proceedings 1996 Springer-Verlag Berlin Heidelb [打印本頁(yè)] 作者: 字里行間 時(shí)間: 2025-3-21 17:17
書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease影響因子(影響力)
書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease影響因子(影響力)學(xué)科排名
書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease被引頻次
書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease被引頻次學(xué)科排名
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書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease讀者反饋
書(shū)目名稱Apolipoprotein E and Alzheimer’s Disease讀者反饋學(xué)科排名
作者: interpose 時(shí)間: 2025-3-21 23:50
Some Basic Things About Computer Arithmeticeisgraber 1994). Early studies had connected apoE to nerve regeneration following injury, where apoE participated in local capture and reutilization of neuronal membrane lipids at the injury site during the degeneration and regeneration processes (Boyles et al. 1989; Pitas et al. 1987; Skene and Sho作者: metropolitan 時(shí)間: 2025-3-22 01:57 作者: octogenarian 時(shí)間: 2025-3-22 05:05 作者: confederacy 時(shí)間: 2025-3-22 10:03 作者: 褪色 時(shí)間: 2025-3-22 14:49
https://doi.org/10.1007/b137928pared to controls. Dendritic alterations were observed as early as 4 months of age. Ultrastructural analysis revealed extensive dendritic vacuolization and disruption of the endomembrane system and cytoskeleton in apoE-deficient homozygous mice. The dendritic damage was accompanied by a decreased im作者: eardrum 時(shí)間: 2025-3-22 17:06 作者: ATOPY 時(shí)間: 2025-3-22 22:56
Multiple-Precision Evaluation of Functionspressed in different cell types and appear to be differentially regulated. Two of them, the low density lipoprotein receptor related protein (LRP) and the very low density lipoprotein receptor (VLDL-r) are located in the vicinity of apoE/A. deposit in the Alzheimer’s brain. This anatomical relations作者: 彎曲的人 時(shí)間: 2025-3-23 04:19 作者: absorbed 時(shí)間: 2025-3-23 05:58
Some Other Shift-and-Add Algorithmslipoprotein E-containing lipoproteins gives rise to complexes that are endocytosed through the LDL receptor-related protein but fails to undergo proteolytic degradation in the lysosomes. These findings may be relevant to the pathobiochemistry of Alzheimer’s disease.作者: 畢業(yè)典禮 時(shí)間: 2025-3-23 12:59 作者: exhilaration 時(shí)間: 2025-3-23 15:49 作者: Concomitant 時(shí)間: 2025-3-23 21:25 作者: Criteria 時(shí)間: 2025-3-23 22:37
,Role of Apolipoprotein E in Alzheimer’s Disease: Clues from its Structure,eisgraber 1994). Early studies had connected apoE to nerve regeneration following injury, where apoE participated in local capture and reutilization of neuronal membrane lipids at the injury site during the degeneration and regeneration processes (Boyles et al. 1989; Pitas et al. 1987; Skene and Sho作者: Alveolar-Bone 時(shí)間: 2025-3-24 03:15
,Apolipoprotein E4, Cholinergic Integrity, Synaptic Plasticity and Alzheimer’s Disease,t in relation to the function of the cholinergic system, which relies to a certain extent on the integrity of phospholipid homeostasis in neurons. Recent evidence indicates that the apoE4 allele has a direct impact on cholinergic function and on cholinomimetic drug response in AD subjects.作者: 創(chuàng)造性 時(shí)間: 2025-3-24 09:00 作者: 安撫 時(shí)間: 2025-3-24 11:40
Apolipoprotein E: Structure, Function, and Possible Roles in Modulating Neurite Extension and Cytos4 without lipid to the dorsal root ganglion or Neuro-2a cells had no effect on neurite outgrowth. The apoE4-mediated effects on inhibition of neurite extension require lipoprotein receptor binding and internalization to elicit the response, and the receptor responsible for the apoE4 effect has been 作者: constitutional 時(shí)間: 2025-3-24 15:39 作者: faculty 時(shí)間: 2025-3-24 23:03 作者: 愚笨 時(shí)間: 2025-3-25 03:00 作者: chondromalacia 時(shí)間: 2025-3-25 04:53 作者: 接觸 時(shí)間: 2025-3-25 10:39 作者: Cardiac 時(shí)間: 2025-3-25 12:37 作者: cardiovascular 時(shí)間: 2025-3-25 17:58 作者: Lipoprotein(A) 時(shí)間: 2025-3-25 22:17
Research and Perspectives in Alzheimer‘s Diseasehttp://image.papertrans.cn/a/image/158983.jpg作者: Desert 時(shí)間: 2025-3-26 01:02 作者: 打算 時(shí)間: 2025-3-26 07:53 作者: Supplement 時(shí)間: 2025-3-26 11:26
Apolipoprotein E and Alzheimer’s Disease978-3-642-80109-9Series ISSN 0945-6066 Series E-ISSN 2196-310X 作者: 裹住 時(shí)間: 2025-3-26 16:34
Polynomial or Rational Approximationst the apolipoprotein E-.4 allele frequency was increased in late-onset familial Alzheimer’s disease. There was no press release or news conference and, in fact, only one mention was made of these data by a reporter from the . who attended the meeting. The first published paper appeared five months l作者: dapper 時(shí)間: 2025-3-26 19:05
Some Basic Things About Computer Arithmeticn alleles of the plasma lipid-transporting protein, apolipoprotein (apo) E, was a major susceptibility gene (Strittmatter et al. 1993a; Corder et al. 1993; Saunders et al. 1993; Roses et al. 1995). It was also demonstrated that allelic variation at the apoE gene locus affects the progression of the 作者: SOB 時(shí)間: 2025-3-27 00:11
Multiple-Precision Evaluation of Functionsand its receptor, the apoE/apoB (LDL) receptor, appears to regulate the transport of cholesterol and phospholipids during the early and intermediate phases of the reinnervation process. During dendritic remodelling and synaptogenesis, neurons progressively repress the synthesis of cholesterol in fav作者: chronicle 時(shí)間: 2025-3-27 01:10
Some Basic Things About Computer Arithmeticect of APOE alleles on disease onset is of key importance to rational treatment of AD. In this study, we employed specific immunocytochemistry to investigate the localization of apoE at different age points in several vertebrate species. These species included laboratory rat, normal and transgenic i作者: BRACE 時(shí)間: 2025-3-27 08:13
https://doi.org/10.1007/b137928rs have suggested that apoE has a role in neurobiology. Most recently it has been associated with the pathogenesis of Alzheimer’s disease. One possible mechanism of apoE involvement in this disease may be modulation of the cytoskeleton in neurons and alteration of neurite extension and branching..Ou作者: 壓倒 時(shí)間: 2025-3-27 10:48 作者: 使虛弱 時(shí)間: 2025-3-27 15:23
Polynomial or Rational Approximationsreceptor and the LDL receptor-related protein/..-macroglobulin receptor (LRP). The VLDLR specifically binds apolipoprotein E (apoE)-containing lipoproteins, including VLDL. Since antibodies to apoE immunostain senile plaques, neurofibrillary tangles and certain neuronal populations in autopsy brains作者: 男生如果明白 時(shí)間: 2025-3-27 19:04
Multiple-Precision Evaluation of Functionsveloping Alzheimer’s disease, there has been intense interest in understand ing the biological mechanisms underlying this genetic predisposition. Apolipoprotein E has been extensively studied in the context of its role in lipid metabolism in plasma, where it binds to lipoproteins and directs them to作者: 微塵 時(shí)間: 2025-3-27 22:31 作者: bromide 時(shí)間: 2025-3-28 03:10
Some Basic Things About Computer Arithmeticsease. Both interactions are thought to be caused by post-translational modifications of the protein. We have analyzed the domain structure of tau, the effect of the domains on tau-tubulin or tau-tau interactions, and the residues that are critically involved. Two key residues appear to be particula作者: 即席演說(shuō) 時(shí)間: 2025-3-28 07:23 作者: ITCH 時(shí)間: 2025-3-28 12:27
Fundamental Concepts and Definitions,zheimer’s disease (AD). APOE4 raises the risk for AD and lowers the mean age of onset in a gene dose-dependent manner, whereas APOE2, a relatively rare allele, decreases the risk and increases the age of onset of disease. The role of apoE in the pathogenesis of AD is not yet known. We have proposed 作者: 能得到 時(shí)間: 2025-3-28 15:13 作者: 藝術(shù) 時(shí)間: 2025-3-28 18:58
https://doi.org/10.1007/978-1-4612-1264-5(Emerit and Chance 1992). The brain is believed to be particularly vulnerable to oxidative damage, as it contains high concentrations of easily peroxidizable lipids (i.e., those rich in polyunsaturated fatty acids), has regions particularly enriched in iron, and has comparatively low to moderate lev作者: glisten 時(shí)間: 2025-3-28 23:16 作者: 曲解 時(shí)間: 2025-3-29 03:48
Graduate Texts in Contemporary Physicslinkage analysis has proven to be both powerful and successful in unraveling the genetic components of AD. Three loci have been identified; the amyloid precursor protein (APP) on chromosome 21, a newly identified gene on chromosome 14 and the apolipoprotein E locus (APOE) on chromosome 19. These loc作者: 使人煩燥 時(shí)間: 2025-3-29 10:19 作者: 翻布尋找 時(shí)間: 2025-3-29 14:10 作者: flavonoids 時(shí)間: 2025-3-29 19:07 作者: 葡萄糖 時(shí)間: 2025-3-29 20:42 作者: Alveoli 時(shí)間: 2025-3-30 01:20
Fundamental Concepts and Definitions,laments or from phosphorylation. To test this hypothesis, we are studying the interaction between apoE isoforms and tau using standard in vitro assays followed by western blotting and the relatively new technique of real-time bimolecular interaction analysis.作者: Mercantile 時(shí)間: 2025-3-30 05:37 作者: 商議 時(shí)間: 2025-3-30 09:26
Interactions of Apolipoprotein E with Microtubule-Associated Proteins,laments or from phosphorylation. To test this hypothesis, we are studying the interaction between apoE isoforms and tau using standard in vitro assays followed by western blotting and the relatively new technique of real-time bimolecular interaction analysis.作者: vitreous-humor 時(shí)間: 2025-3-30 12:24 作者: 難理解 時(shí)間: 2025-3-30 18:39 作者: Monotonous 時(shí)間: 2025-3-30 21:46
Graduate Texts in Contemporary Physicsage) families. The results of these analyses have shown three chromosomal regions that could potentially contain additional AD susceptibility loci. These regions of interest will be further evaluated using additional markers and AD families to confirm these initial findings.作者: emulsify 時(shí)間: 2025-3-31 02:37 作者: 難聽(tīng)的聲音 時(shí)間: 2025-3-31 05:07
0945-6066 ith late-onset Alzheimer‘s disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer‘s disease are new and exciting avenues of research. This book, written by the most outstanding作者: linguistics 時(shí)間: 2025-3-31 09:59 作者: 星球的光亮度 時(shí)間: 2025-3-31 17:14
,Role of Apolipoprotein E in Alzheimer’s Disease: Clues from its Structure,n alleles of the plasma lipid-transporting protein, apolipoprotein (apo) E, was a major susceptibility gene (Strittmatter et al. 1993a; Corder et al. 1993; Saunders et al. 1993; Roses et al. 1995). It was also demonstrated that allelic variation at the apoE gene locus affects the progression of the 作者: Small-Intestine 時(shí)間: 2025-3-31 19:29 作者: 懸掛 時(shí)間: 2025-4-1 00:27
