作者: anus928 時(shí)間: 2025-3-21 20:38
978-3-0348-9581-1Springer Basel AG 2000作者: Patrimony 時(shí)間: 2025-3-22 00:34 作者: 印第安人 時(shí)間: 2025-3-22 04:59
Joachim Richter,Ulrich Gasselingfailed to show antipsychotic efficacy in ten hospitalized schizophrenic inpatients receiving a mean dose of 1,470 mg [.]. On the contrary, a growing appreciation for buspirone’s unexpected anxiolytic, but not antipsychotic properties [., .] ultimately influenced the nature of its prospective develop作者: 殺子女者 時(shí)間: 2025-3-22 11:27
Herbert Niederhausen,Andreas Burkertght be useful in the treatment of anxiety disorders. Meprobamate and the first benzodiazepines were effective in alleviating anxiety, while imipramine given in a single dose often accentuated tension and agitation. During the later part of that decade Klein and Fink [.] observed that inpatients with作者: MOCK 時(shí)間: 2025-3-22 15:02
Herbert Niederhausen,Andreas Burkertlts in changes in cerebral function. Monoamine oxidase metabolizes and thus inactivates endogenous pressor amines (like serotonin and noradrenaline) as well as ingested amines absorbed from the gut (like tyramine). The therapeutic effect of MAOIs is supposed to be linked to an inhibition of the degr作者: condescend 時(shí)間: 2025-3-22 19:00
Die Verbreitung des elektrischen Kochens,m and long-term treatment. The efficacy of SSRIs is similar to that of tricyclic antidepressants (TCAs) in patients with major depression, apart from in the subgroup of hospitalised in-patients, where TCAs are marginally, but significantly, more effective [.]. In randomised controlled trials, the to作者: 臆斷 時(shí)間: 2025-3-22 23:41
,Ger?te für die elektrische Haushaltküche,anticonvulsant and muscle relaxant properties and their relative safety, rapidly elevated BZs to the treatment of choice for common and recurrent conditions such as anxiety states, tension and insomnia. However, in recent years, attitudes toward these compounds have greatly changed, and growing awar作者: Ambulatory 時(shí)間: 2025-3-23 04:03 作者: FLAGR 時(shí)間: 2025-3-23 08:23 作者: 證實(shí) 時(shí)間: 2025-3-23 10:16 作者: achlorhydria 時(shí)間: 2025-3-23 17:27 作者: anchor 時(shí)間: 2025-3-23 18:24 作者: 享樂(lè)主義者 時(shí)間: 2025-3-24 01:02
Anxiolytics978-3-0348-8470-9Series ISSN 2296-6056 Series E-ISSN 2296-6064 作者: FAZE 時(shí)間: 2025-3-24 04:50 作者: headway 時(shí)間: 2025-3-24 07:50
,Me?wertaufnehmer für mechanische Gr??en,he assembly and operation of NMDA receptors in the central nervous system. While a review of all aspects of NMDA receptor biology is clearly beyond the scope of this chapter, it is important to review, however briefly, the salient features of NMDA receptors of particular relevance to drug design and development.作者: palliative-care 時(shí)間: 2025-3-24 13:58 作者: 簡(jiǎn)略 時(shí)間: 2025-3-24 15:39
5-HT1B/D receptors in anxiety,irst part of this book. Among other neurotransmitters potentially involved in anxiety, serotonin (5-hydroxytryptamine, 5-HT) of course has a very prominent place. The neuropharmacology of 5-HT has been fundamentally revised in recent years with the discovery of multiple serotonin receptor subtypes [.].作者: 爆炸 時(shí)間: 2025-3-24 20:21
Glutamate receptor ligands,he assembly and operation of NMDA receptors in the central nervous system. While a review of all aspects of NMDA receptor biology is clearly beyond the scope of this chapter, it is important to review, however briefly, the salient features of NMDA receptors of particular relevance to drug design and development.作者: Judicious 時(shí)間: 2025-3-25 00:41 作者: Limited 時(shí)間: 2025-3-25 06:36 作者: 歡騰 時(shí)間: 2025-3-25 11:03
Herbert Niederhausen,Andreas BurkertMAO-B. In humans, dopamine is deaminated by both MAOs, hence the use of MAOIs in Parkinson’s disease. First generation MAOIs are non-selective (inhibiting both enzymes) and irreversible, meaning that MAO is permanently inhibited by their action. MAO activity only resumed after treatment had been dis作者: LURE 時(shí)間: 2025-3-25 13:58
,Ger?te für die elektrische Haushaltküche,ctions and without the concomitant unwanted effects has led to the development of drugs that selectively bind to specific BZ/w receptor subtypes and/or show different efficacies at BZ/u) receptors. For example, studies in animals showed that the non-selective BZ/w receptor partial agonists bretazeni作者: LIEN 時(shí)間: 2025-3-25 17:15
Verfahrenstechnische Messungen,al of the antidepressant venlafaxine (Wyeth-Ayrst) (a mixed 5HT and noradrenergic uptake inhibitor at higher doses) for generalized anxiety disorder (GAD), there were no successors to buspirone or the benzodiazepines in the United States or Europe.作者: 我怕被刺穿 時(shí)間: 2025-3-25 20:29
,Empfindlichkeit, Aufl?sung und Fehler,d immunolocalization of 5HT.receptors reveal a similar overall distribution [., .] and species differences between rat and human brain distribution are limited [.]. Their dense presence in limbic and cortical regions is consistent with a possible important role in affective disorders such as anxiety作者: 座右銘 時(shí)間: 2025-3-26 02:46
Book 2000order (GAD), specific phobias, social phobias and post-traumatic stress disorder (PTSD). These new clinical categories have opened another dimension in the therapy of anxiety requiring the optimisation of treatments for different syndromes. This book is a critical review of today‘s anxiolytics and t作者: Adherent 時(shí)間: 2025-3-26 05:48 作者: Individual 時(shí)間: 2025-3-26 09:16 作者: Axon895 時(shí)間: 2025-3-26 15:23 作者: 大看臺(tái) 時(shí)間: 2025-3-26 18:47 作者: irreducible 時(shí)間: 2025-3-26 22:39 作者: 高興一回 時(shí)間: 2025-3-27 04:06 作者: idiopathic 時(shí)間: 2025-3-27 07:04
2296-6056 imension in the therapy of anxiety requiring the optimisation of treatments for different syndromes. This book is a critical review of today‘s anxiolytics and t978-3-0348-9581-1978-3-0348-8470-9Series ISSN 2296-6056 Series E-ISSN 2296-6064 作者: 喚醒 時(shí)間: 2025-3-27 11:10
,Energiebedarf und Berechnung der ?fen,which was more potent and had a broader spectrum of activity than chlordiazepoxide [.], was introduced in 1963. Since then, numerous analogues of the benzodiazepine structure have been developed and introduced into clinical practice.作者: MIRTH 時(shí)間: 2025-3-27 15:11 作者: embolus 時(shí)間: 2025-3-27 21:05 作者: 負(fù)擔(dān) 時(shí)間: 2025-3-27 23:42
Peptide receptors as targets for anxiolytic drugs,ile the development of specific receptor ligands (agonists and antagonists) helps to elucidate their functional role. Most of the research so far has been conducted in animals, but human data have started to accumulate.作者: Affectation 時(shí)間: 2025-3-28 05:37
The benzodiazepines: a brief review of pharmacology and therapeutics,which was more potent and had a broader spectrum of activity than chlordiazepoxide [.], was introduced in 1963. Since then, numerous analogues of the benzodiazepine structure have been developed and introduced into clinical practice.作者: obsolete 時(shí)間: 2025-3-28 06:34 作者: 危險(xiǎn) 時(shí)間: 2025-3-28 10:33 作者: graphy 時(shí)間: 2025-3-28 16:26
Book 2000mal tests developed since the 1960s have been optimised for the benzodiazepines and some programmes have even screened candidates as potential anxiolytics on their benzodiazepine-like side-effects rather than their anxiolytic activity. With the realisation of the drawbacks of the benzodiazepines, na作者: stressors 時(shí)間: 2025-3-28 21:33
The benzodiazepines: a brief review of pharmacology and therapeutics, nucleus benzo-1, 4-diazepine structure. One compound, chlordiazepoxide (Fig. 1), exhibited sedative, anticonvulsant and muscle relaxant properties, which were confirmed by clinical studies and was launched as an anxiolytic in 1960 under the trade name Librium. A second compound, diazepam (valium), 作者: 觀點(diǎn) 時(shí)間: 2025-3-29 01:49 作者: JUST 時(shí)間: 2025-3-29 03:10 作者: 抱狗不敢前 時(shí)間: 2025-3-29 08:30
Monoamine oxidase inhibitors (including the newer reversible compounds),lts in changes in cerebral function. Monoamine oxidase metabolizes and thus inactivates endogenous pressor amines (like serotonin and noradrenaline) as well as ingested amines absorbed from the gut (like tyramine). The therapeutic effect of MAOIs is supposed to be linked to an inhibition of the degr作者: 無(wú)節(jié)奏 時(shí)間: 2025-3-29 15:05
Selective serotonin re-uptake inhibitors in anxiety disorders: room for improvement,m and long-term treatment. The efficacy of SSRIs is similar to that of tricyclic antidepressants (TCAs) in patients with major depression, apart from in the subgroup of hospitalised in-patients, where TCAs are marginally, but significantly, more effective [.]. In randomised controlled trials, the to作者: 類(lèi)似思想 時(shí)間: 2025-3-29 17:21
