標(biāo)題: Titlebook: Anxiety and Anxiolytic Drugs; Florian Holsboer,Andreas Str?hle Book 2005 Springer-Verlag Berlin Heidelberg 2005 Anxiety.Anxiolytic Drugs.N [打印本頁(yè)] 作者: Opiate 時(shí)間: 2025-3-21 17:15
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs影響因子(影響力)
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs被引頻次
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs被引頻次學(xué)科排名
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs年度引用
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs年度引用學(xué)科排名
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs讀者反饋
書(shū)目名稱(chēng)Anxiety and Anxiolytic Drugs讀者反饋學(xué)科排名
作者: Grating 時(shí)間: 2025-3-21 20:17
https://doi.org/10.1007/978-3-7091-5725-1Pharmacogenetics as a field of research is increasing the basis of knowledge on the use of psychotropics in different ethnic patient populations. This chapter summarizes current knowledge on the metabolism of anxiolytic agents with emphasis on pharmacogenetics and ethnic variations in drug responses.作者: chassis 時(shí)間: 2025-3-22 03:36 作者: 水汽 時(shí)間: 2025-3-22 07:33
https://doi.org/10.1007/3-540-28082-0Anxiety; Anxiolytic Drugs; Neuropsychopharmacology; Neuroscience; Pharmacology; neuropeptides; pathophysio作者: 導(dǎo)師 時(shí)間: 2025-3-22 10:01 作者: 名義上 時(shí)間: 2025-3-22 14:31
Florian Holsboer,Andreas Str?hleIncludes supplementary material: 作者: 使高興 時(shí)間: 2025-3-22 21:04
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/a/image/158855.jpg作者: 鞠躬 時(shí)間: 2025-3-22 23:34
https://doi.org/10.1007/978-3-7091-8387-8tic stress disorder. Basic research performed in laboratory animals may help to elucidate the aetiology of the respective diseases. This chapter gives a short introduction into theoretical and practical aspects of animal experiments aimed at investigating acquisition, consolidation and extinction of作者: 路標(biāo) 時(shí)間: 2025-3-23 02:25
Physiologische Eigenschaften der AEP, adaptive response to an unfamiliar environment, especially when confronted with danger or threat. However, pathological variants of anxiety can strongly impede the daily life of those affected. To unravel neurobiological mechanisms underlying normal anxiety as well as its pathological variations, a作者: 貪婪地吃 時(shí)間: 2025-3-23 09:26
Klinische Einsatzgebiete der AEP,ous controversies in intellectual history. Although current views emphasize the joint influence of genes and environmental sources during early brain development, the physiological complexities of multiple gene-gene and gene-environment interactions in the developmental neurobiology of fear and anxi作者: SNEER 時(shí)間: 2025-3-23 11:36
https://doi.org/10.1007/978-3-642-53210-8 to play a causal role in the etiology and symptomatology of anxiety disorders. Indeed, there is increasing evidence from basic science that chronic stress-induced perturbation of CRH and AVP neurocircuitries may contribute to abnormal neuronal communication in conditions of pathological anxiety. An作者: EXCEL 時(shí)間: 2025-3-23 17:33
https://doi.org/10.1007/978-3-642-53210-8substance P (SP) and its cognate receptor neurokinin 1 (NK1R) seem to play a particularly important role in higher brain functions. They are expressed at high levels in the limbic system, which is the neural basis of emotional responses. Three different lines of evidence from physiological studies s作者: Preserve 時(shí)間: 2025-3-23 18:57
https://doi.org/10.1007/978-3-642-53210-8ty disorder, and obsessive—compulsive disorder. Controlled family studies reveal that all of these anxiety subtypes are familial, and twin studies suggest that the familial aggregation is attributable in part to genetic factors. Panic disorder and, its spectrum have the strongest magnitude of famili作者: 陳列 時(shí)間: 2025-3-24 00:12
https://doi.org/10.1007/978-3-662-36767-4panic disorder, has been increasing steadily during the past several years. Although the picture is far from complete yet—partly due to the large number of serotonin (5-HT) receptors and the often-disparate effects of receptor agonists and antagonists in animal models of anxiety—SSRIs and the 5-HT. 作者: DAMN 時(shí)間: 2025-3-24 03:51
https://doi.org/10.1007/978-3-662-36767-4e systems have been demonstrated to play important roles in the behaviors associated with fear and anxiety-producing stimuli. Long-term dysregulation of these systems appears to contribute to the development of anxiety disorders, including panic disorder, posttraumatic stress disorder (PTSD), and so作者: 偏狂癥 時(shí)間: 2025-3-24 06:34 作者: 忍耐 時(shí)間: 2025-3-24 14:45 作者: 蝕刻術(shù) 時(shí)間: 2025-3-24 15:08
Zeit-Strom-Verhalten bis zum Unterbrechen,lasticity may play a role in the pathophysiology of anxiety. Intracellular signaling pathways are known in many systems to be critical links in the cascades from surface signals to the molecular alterations that result in functional plasticity. Chronic antidepressant treatments can regulate intracel作者: 減至最低 時(shí)間: 2025-3-24 20:53
Zeit-Strom-Verhalten bis zum Unterbrechen,e as endogenous modulators of complex behaviours, including anxiety-related behaviour and psychopathology, particularly due to their high number and diversity, the dynamics of release patterns in distinct brain areas and the multiple and variable modes of interneuronal communication they are involve作者: 聾子 時(shí)間: 2025-3-25 01:51 作者: Alcove 時(shí)間: 2025-3-25 03:27 作者: intrigue 時(shí)間: 2025-3-25 09:29 作者: 壓倒性勝利 時(shí)間: 2025-3-25 13:14 作者: 密切關(guān)系 時(shí)間: 2025-3-25 17:16 作者: Peristalsis 時(shí)間: 2025-3-25 20:22
Physiologische Eigenschaften der AEP,idity). Meeting these three requirements is difficult for any animal model. Since both the physiological and the behavioral response to aversive (threatening) stimuli are similar in humans and animals, it can be assumed that animal models can serve at least two distinct purposes: as (1) behavioral t作者: 激勵(lì) 時(shí)間: 2025-3-26 00:48 作者: 巫婆 時(shí)間: 2025-3-26 06:33 作者: Extemporize 時(shí)間: 2025-3-26 11:10 作者: 善于 時(shí)間: 2025-3-26 12:50 作者: indifferent 時(shí)間: 2025-3-26 20:18
https://doi.org/10.1007/978-3-662-36767-4earch pertinent to the neurobiological basis of anxiety disorders. The implications of this synthesis for the discovery of anxiety disorder vulnerability genes and novel psychopharmacological approaches will also be discussed.作者: Friction 時(shí)間: 2025-3-26 23:07 作者: infringe 時(shí)間: 2025-3-27 02:27
Zeit-Strom-Verhalten bis zum Unterbrechen,es for additional signaling pathways; however, less is known about such mechanisms in anxiety. The challenge to identify intracellular signaling pathways and related molecular and structural changes that are critical to the etiology and treatment of anxiety will further establish the importance of m作者: 成份 時(shí)間: 2025-3-27 05:23 作者: 入伍儀式 時(shí)間: 2025-3-27 11:35
,Bauarten der elektrischen ?fen,ld not be defined reliably. On the basis of evidence that imipramine can block panic attacks, panic disorder was created as a new diagnosis for the first time in DSM-III. Anxiety states without spontaneous panic attacks were separated from panic disorder and defined as a residual category, generaliz作者: admission 時(shí)間: 2025-3-27 15:01
,Die Schwei?ung durch Elektrolyse, further field where benefits for the treatment of anxiety disorders could be achieved. Although the road of drug development is arduous, improvements in the pharmacological treatment of anxiety disorders are expected for the near future.作者: PUT 時(shí)間: 2025-3-27 19:16
,Die gas-elektrischen Schwei?verfahren,In order to know whether they can be extrapolated to patients with anxiety disorders, clinical studies are warranted. Despite all the shortcomings of the currently available pharmacogenetic studies, this field holds great promise for the treatment of anxiety disorders. In the future, psychiatrists m作者: Optimum 時(shí)間: 2025-3-28 00:20
Animal Models of Anxiety,idity). Meeting these three requirements is difficult for any animal model. Since both the physiological and the behavioral response to aversive (threatening) stimuli are similar in humans and animals, it can be assumed that animal models can serve at least two distinct purposes: as (1) behavioral t作者: EWE 時(shí)間: 2025-3-28 05:44
Genetic Alterations of the Murine Serotonergic Gene Pathway: The Neurodevelopmental Basis of Anxietave been modified by deletion of genes coding for key players of serotonergic neurotransmission. In particular, pertinent approaches regarding phenotypic changes in mice bearing inactivation mutations of 5-HT receptors, 5-HT transporter, and monoamine oxidase A and other genes related to 5-HT signal作者: rectocele 時(shí)間: 2025-3-28 07:58
Mutagenesis and Knockout Models: Hypothalamic-Pituitary-Adrenocortical System,dies performed in such mice have complemented and extended our knowledge. The cumulative evidence makes a strong case implicating dysfunction of CRH-related systems in the pathogenesis of anxiety disorders and depression and leads us beyond the monoaminergic synapse in search of eagerly anticipated 作者: 商店街 時(shí)間: 2025-3-28 14:21 作者: Biguanides 時(shí)間: 2025-3-28 18:14 作者: 制定法律 時(shí)間: 2025-3-28 20:11
Anxiety Disorders: Noradrenergic Neurotransmission,earch pertinent to the neurobiological basis of anxiety disorders. The implications of this synthesis for the discovery of anxiety disorder vulnerability genes and novel psychopharmacological approaches will also be discussed.作者: 欺騙手段 時(shí)間: 2025-3-28 22:56
Excitatory Amino Acid Neurotransmission,nd 2,3-benzodiazepines also show more promise than e.g. competitive antagonists. Great progress has also been made in the field of metabotropic glutamate receptors since the discovery of novel, allosteric modulatory sites for these receptors. Selective agents acting at these transmembrane sites have作者: HEW 時(shí)間: 2025-3-29 05:57
Neurobiology and Treatment of Anxiety: Signal Transduction and Neural Plasticity,es for additional signaling pathways; however, less is known about such mechanisms in anxiety. The challenge to identify intracellular signaling pathways and related molecular and structural changes that are critical to the etiology and treatment of anxiety will further establish the importance of m作者: Ingenuity 時(shí)間: 2025-3-29 08:37 作者: 你不公正 時(shí)間: 2025-3-29 13:09 作者: MAPLE 時(shí)間: 2025-3-29 17:09 作者: observatory 時(shí)間: 2025-3-29 20:19
Pharmacogenomics,In order to know whether they can be extrapolated to patients with anxiety disorders, clinical studies are warranted. Despite all the shortcomings of the currently available pharmacogenetic studies, this field holds great promise for the treatment of anxiety disorders. In the future, psychiatrists m作者: rectum 時(shí)間: 2025-3-30 01:37
Learning and Memory,tic stress disorder. Basic research performed in laboratory animals may help to elucidate the aetiology of the respective diseases. This chapter gives a short introduction into theoretical and practical aspects of animal experiments aimed at investigating acquisition, consolidation and extinction of作者: Carbon-Monoxide 時(shí)間: 2025-3-30 06:48 作者: comely 時(shí)間: 2025-3-30 11:39 作者: ARBOR 時(shí)間: 2025-3-30 13:41 作者: Fallibility 時(shí)間: 2025-3-30 18:12
Mutagenesis and Knockout Models: NK1 and Substance P,substance P (SP) and its cognate receptor neurokinin 1 (NK1R) seem to play a particularly important role in higher brain functions. They are expressed at high levels in the limbic system, which is the neural basis of emotional responses. Three different lines of evidence from physiological studies s作者: 共和國(guó) 時(shí)間: 2025-3-31 00:05
Genetic Epidemiology of Anxiety Disorders,ty disorder, and obsessive—compulsive disorder. Controlled family studies reveal that all of these anxiety subtypes are familial, and twin studies suggest that the familial aggregation is attributable in part to genetic factors. Panic disorder and, its spectrum have the strongest magnitude of famili作者: 分期付款 時(shí)間: 2025-3-31 02:33
Interactions Between Corticotropin-Releasing Hormone and Serotonin: Implications for the Aetiology panic disorder, has been increasing steadily during the past several years. Although the picture is far from complete yet—partly due to the large number of serotonin (5-HT) receptors and the often-disparate effects of receptor agonists and antagonists in animal models of anxiety—SSRIs and the 5-HT. 作者: PURG 時(shí)間: 2025-3-31 08:32 作者: ureter 時(shí)間: 2025-3-31 11:19 作者: impaction 時(shí)間: 2025-3-31 14:20 作者: meditation 時(shí)間: 2025-3-31 19:13 作者: isotope 時(shí)間: 2025-3-31 22:49
Neuropeptides in Anxiety Modulation,e as endogenous modulators of complex behaviours, including anxiety-related behaviour and psychopathology, particularly due to their high number and diversity, the dynamics of release patterns in distinct brain areas and the multiple and variable modes of interneuronal communication they are involve作者: 滋養(yǎng) 時(shí)間: 2025-4-1 04:36
Neuroendocrine Aspects of PTSD,erations in PTSD and highlight alterations relevant to the identification of targets for drug development. Most studies demonstrate alterations consistent with an enhanced negative feedback inhibition of cortisol on the pituitary, an overall hyperreactivity of other target tissues (adrenal gland, hy作者: PALSY 時(shí)間: 2025-4-1 09:32
Anxiety Disorders: Clinical Presentation and Epidemiology,owledge is largely related to the classification of anxiety disorders as presented by the Diagnostic and Statistical Manual of Mental Disorders since its third revision (DSM-III). Without going into detail into the history of the classification of anxiety disorders and into the history and developme作者: Trypsin 時(shí)間: 2025-4-1 13:03 作者: colony 時(shí)間: 2025-4-1 16:14
New Pharmacological Treatment Approaches for Anxiety Disorders,s including evolving techniques of genomics and proteomics will generate new drug targets. Drug development design will generate new pharmacological substances with specific action at specific neurotransmitter and neuropeptide receptors or affecting their reuptake and metabolism. New anxiolytic drug作者: figurine 時(shí)間: 2025-4-1 19:30
Pharmacogenomics,uch disorders. For example, pharmacokinetic aspects of antidepressant drug therapy likely also apply to patients with anxiety disorders, and several genetic polymorphisms in the cytochrome P450 (CYP) gene family and drug transporter molecules, such as the multidrug resistance (MDR) gene type 1, have作者: 高爾夫 時(shí)間: 2025-4-2 01:09
Pathophysiology and Pharmacology of GABAA Receptors,ed. A new central nervous system pharmacology is on the horizon. The development of anxiolytic drugs devoid of sedation and of agents that enhance hippocampus-dependent learning and memory has become a novel and highly selective therapeutic opportunity.作者: dry-eye 時(shí)間: 2025-4-2 03:56
Neuroendocrine Aspects of PTSD,pothalamus), or both in PTSD. However, findings of low cortisol and increased reactivity of the pituitary in PTSD are also consistent with reduced adrenal output. The observations in PTSD are part of a growing body of neuroendocrine data providing evidence of insufficient glucocorticoid signaling in stress-related neuropsychiatric disorders.
