標題: Titlebook: Antisense Therapeutics; M. Ian Phillips Book 2005Latest edition Humana Press 2005 RNA.apoptosis.cancer.cancer therapy.cell.drug.drug deliv [打印本頁] 作者: Weber-test 時間: 2025-3-21 19:05
書目名稱Antisense Therapeutics影響因子(影響力)
書目名稱Antisense Therapeutics影響因子(影響力)學科排名
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書目名稱Antisense Therapeutics網(wǎng)絡公開度學科排名
書目名稱Antisense Therapeutics被引頻次
書目名稱Antisense Therapeutics被引頻次學科排名
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書目名稱Antisense Therapeutics年度引用學科排名
書目名稱Antisense Therapeutics讀者反饋
書目名稱Antisense Therapeutics讀者反饋學科排名
作者: 是他笨 時間: 2025-3-21 22:19 作者: 冒號 時間: 2025-3-22 01:19 作者: TRAWL 時間: 2025-3-22 06:12
Antisense Therapeutics for Hypertension of hypertension, the number of patients with controlled hypertension is about 27% in the United States. In all other countries studied, even those such as the United Kingdom and Canada, where cost is not a major factor, patient compliance is even worse. Part of the reason for this problem is that c作者: 集合 時間: 2025-3-22 11:49 作者: 白楊 時間: 2025-3-22 15:46
Clinical Studies of Antisense Oligonucleotides for Cancer Therapyhemotherapeutic drugs designed to perturb DNA synthesis or the mitotic event. The development of cytotoxic agents has resulted in improvements in the treatment of leukemia, lymphoma, testicular cancer, and many other solid tumor types (.). Hormone-based drugs have also been useful for breast and pro作者: 巧思 時間: 2025-3-22 18:40
Antisense Therapy in Clinical Oncologyan antisense oligonucleotide (AS-ODN) to the target mRNA makes the antisense strategy attractive for selectively modulating the expression of genes involved in the pathogenesis of malignant or nonmalignant diseases. One antisense drug has been approved for local therapy of cytomegalovirus (CMV) reti作者: 龍卷風 時間: 2025-3-22 23:45
Radionuclide-Peptide Nucleic Acid in Diagnosis and Treatment of Pancreatic Cancerreas (hereafter simply referred to as pancreatic cancer) occurs more frequently in African-Americans than in European-Americans. The disease progresses rapidly. Pancreatic cancer is usually refractory to treatment, with a median survival time of 12 mo. Overall, only 1% of patients live more than 5 y作者: Altitude 時間: 2025-3-23 02:17 作者: 表示向下 時間: 2025-3-23 06:32
Induction of Tumor Cell Apoptosis and Chemosensitization by Antisense Strategiese use of antisense oligodeoxynucleotides (AS-DONs) directed against gene products overexpressed in tumor cells in synergy with other anticancer agents. In contrast to the low basal levels of the mitogen-dependent cyclin D1 and of the DNA-damage-inducible p53 tumor suppressor protein, tumors with gre作者: 鞭打 時間: 2025-3-23 11:29 作者: opinionated 時間: 2025-3-23 17:01
Transport of Antisense Across the Blood-Brain Barrier-production of endogenous protein. Administration of antisense therapy could be difficult, however, because peripherally administered antisense would have to cross the blood-brain barrier (BBB) in effective quantities. Several studies have investigated various modifications that can be introduced in作者: scotoma 時間: 2025-3-23 20:09
Transdermal Delivery of Antisense OligonucletoidesThis reduces degradation by the acid and proteolytic enzymes in the gastric environment (.), as well hepatic first-pass elimination (.) and incomplete absorption due to GI motility disorders (.). Transdermal delivery also provides steady-state drug levels and improves patient compliance because of i作者: 浪費時間 時間: 2025-3-24 02:15
1543-1894 e, brain disorders, the blood-brain barrier, and drug delivery.Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs.978-1-61737-421-0978-1-59259-854-0Series ISSN 1543-1894 Series E-ISSN 1940-6037 作者: 碎石 時間: 2025-3-24 04:38 作者: otic-capsule 時間: 2025-3-24 08:47
Book 2005Latest editionides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery.Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous poten作者: 馬賽克 時間: 2025-3-24 12:54 作者: 合同 時間: 2025-3-24 15:07
Charge and magnetization densities, and DNA methyltransferase. Clinical studies indicate that AS-ODNs are well tolerated and may have therapeutic activity. In this overview, we summarize therapeutic concepts, clinical studies, and new promising molecular targets to treat human cancer with AS-ODNs.作者: Scintigraphy 時間: 2025-3-24 19:13
Antisense Therapeutics for Hypertensionn reason for patients interrupting their treatment. By not controlling their BP over 24 h, patients experience troughs and peaks in blood pressure (BP). A common regimen of taking a pill in the morning increases the likelihood of stroke or heart attacks at that time, when control is at its weakest.作者: Defiance 時間: 2025-3-25 01:27 作者: encyclopedia 時間: 2025-3-25 04:37
Antisense Inhibitionh the discovery of RNA interference (RNAi) and development in delivery of these gene drugs, more preclinical and clinical investigations are anticipated to take place in the near future to finally fulfill the promise of antisense therapeutics in humans.作者: Throttle 時間: 2025-3-25 07:28
Springer Series in Solid-State Sciencesf the current lack of a reliable method for early diagnosis, we propose noninvasive measurement of the oncogene expression profile of the cancer and subsequent ablation of those cells expressing the activating oncogenes.作者: deciduous 時間: 2025-3-25 12:30 作者: 織物 時間: 2025-3-25 16:55 作者: 圖畫文字 時間: 2025-3-25 20:32
Radionuclide-Peptide Nucleic Acid in Diagnosis and Treatment of Pancreatic Cancerf the current lack of a reliable method for early diagnosis, we propose noninvasive measurement of the oncogene expression profile of the cancer and subsequent ablation of those cells expressing the activating oncogenes.作者: Hyperalgesia 時間: 2025-3-26 02:02
Utility of Antioncogene Ribozymes and Antisense Oligonucleotides in Reversing Drug Resistanceo anticancer drugs: cisplatin, which is exceptionally effective against testicular cancer, ovarian cancer, and others (.); and Ara-C (1-β-.-arabinofuranosyl cytidine, cytosine arabinoside), now a standard for the treatment of acute and chronic leukemia (.).作者: Muffle 時間: 2025-3-26 04:40
Transdermal Delivery of Antisense Oligonucletoidesc systemic levels. The disadvantages of transdermal delivery include limited numbers of potential drug candidates due to their inability to penetrate the skin in sufficient levels, and potential irritation at the application site (.).作者: CHASE 時間: 2025-3-26 11:40 作者: 充氣球 時間: 2025-3-26 12:39 作者: 溝通 時間: 2025-3-26 19:10
Local Application of Antisense for Prevention of Restenosis.). The artery is injured at the site of PTCA, leading to wound healing responses including thrombosis, smooth muscle proliferation and migration, elastic recoil, and vascular remodeling. Each of these responses may contribute to recurrent obstruction or vessel narrowing, referred to as restenosis.作者: chronicle 時間: 2025-3-26 23:07 作者: faction 時間: 2025-3-27 03:03
Antisense Strategies for the Treatment of Heart Failured by SERCA2a and approx 30% by the Na./Ca. exchanger (.). The Ca. pumping activity of SERCA2a is influenced by phospholamban. In the unphosphorylated state, phospholamban inhibits the Ca.-ATPase, whereas phosphorylation of phospholamban by cyclic adenosine monophosphate (cAMP)-dependent protein kina作者: 谷類 時間: 2025-3-27 06:06 作者: Constrain 時間: 2025-3-27 11:11 作者: dissolution 時間: 2025-3-27 17:40 作者: Irrepressible 時間: 2025-3-27 21:20
Transport of Antisense Across the Blood-Brain Barrier (OTS-1) (.). Another unmodified P-ODN was also shown to cross the BBB. This P-ODN was directed at methionine enkephalin (Met-Enk), an opiate peptide associated with alcoholism (unpublished results). The second type of unmodified analog shown to cross the BBB is a peptide nucleic acid (PNA) that was作者: braggadocio 時間: 2025-3-27 22:30
https://doi.org/10.1007/b138290failed to show statistically significant benefits as an antisense therapy for the treatment of non-small cell carcinoma of the lung better than the median survival with control treatments. The results nevertheless proved that antisense was well tolerated and tended toward greater benefit to the surv作者: 人造 時間: 2025-3-28 04:00
Charge and magnetization densities,d by SERCA2a and approx 30% by the Na./Ca. exchanger (.). The Ca. pumping activity of SERCA2a is influenced by phospholamban. In the unphosphorylated state, phospholamban inhibits the Ca.-ATPase, whereas phosphorylation of phospholamban by cyclic adenosine monophosphate (cAMP)-dependent protein kina作者: 蹣跚 時間: 2025-3-28 06:32
,Green’s functions: an in-between summary,ibitors of cell-signaling pathways that have been linked to oncogenesis or maintenance of the malignant phenotype. For example, the former approach has seen the development and licensing of Herceptin? (trastuzumab; Genentech/Roche), a humanized MAb that targets erbB2/HER2, a receptor tyrosine kinase作者: TRAWL 時間: 2025-3-28 13:17 作者: 輕推 時間: 2025-3-28 15:35 作者: Obsequious 時間: 2025-3-28 20:11
Springer Series in Solid-State Sciences (OTS-1) (.). Another unmodified P-ODN was also shown to cross the BBB. This P-ODN was directed at methionine enkephalin (Met-Enk), an opiate peptide associated with alcoholism (unpublished results). The second type of unmodified analog shown to cross the BBB is a peptide nucleic acid (PNA) that was作者: 天真 時間: 2025-3-28 23:08
https://doi.org/10.1385/1592598544RNA; apoptosis; cancer; cancer therapy; cell; drug; drug delivery; drug resistance; hepatitis; metabolism; nuc作者: grandiose 時間: 2025-3-29 05:11 作者: Visual-Acuity 時間: 2025-3-29 09:42
Book 2005Latest editionides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery.Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs.作者: 固執(zhí)點好 時間: 2025-3-29 14:04
M. Ian PhillipsIncludes supplementary material: 作者: 原始 時間: 2025-3-29 15:41
Methods in Molecular Medicinehttp://image.papertrans.cn/a/image/158676.jpg作者: 亞當心理陰影 時間: 2025-3-29 22:21 作者: 尖 時間: 2025-3-30 02:42
Springer Series in Solid-State Sciencesition of ribozymes and, more recently, to the inclusion of small interfering RNAs (siRNAs). Antisense therapeutics has also experienced its phases of high expectation, sudden disappointment, and meticulous rediscovery, while maintaining its status as a viable and effective gene therapy approach. Wit作者: 爭吵加 時間: 2025-3-30 07:28
Electron Scattering in Solid Matter artery disease (.). PTCA treatment has since become more extensive and gained favor as an alternative treatment for coronary artery bypass grafting (.). The artery is injured at the site of PTCA, leading to wound healing responses including thrombosis, smooth muscle proliferation and migration, ela作者: 把手 時間: 2025-3-30 09:28 作者: thalamus 時間: 2025-3-30 14:22
