標題: Titlebook: Antiplatelet Agents; Paolo Gresele,Gustav V. R Born,Clive P. Page Book 2012 Springer-Verlag Berlin Heidelberg 2012 Antithrombotic Therapy. [打印本頁] 作者: 航天飛機 時間: 2025-3-21 18:08
書目名稱Antiplatelet Agents影響因子(影響力)
書目名稱Antiplatelet Agents影響因子(影響力)學科排名
書目名稱Antiplatelet Agents網(wǎng)絡公開度
書目名稱Antiplatelet Agents網(wǎng)絡公開度學科排名
書目名稱Antiplatelet Agents被引頻次
書目名稱Antiplatelet Agents被引頻次學科排名
書目名稱Antiplatelet Agents年度引用
書目名稱Antiplatelet Agents年度引用學科排名
書目名稱Antiplatelet Agents讀者反饋
書目名稱Antiplatelet Agents讀者反饋學科排名
作者: 指耕作 時間: 2025-3-21 22:03
Platelets: Production, Morphology and Ultrastructuresmic reticulum that form the dense tubular system (DTS); a spectrin-based membrane skeleton; an actin-based cytoskeletal network; a peripheral band of microtubules; and numerous organelles including α-granules, dense-granules, peroxisomes, lysosomes, and mitochondria. Proplatelet elongation and plat作者: 松軟 時間: 2025-3-22 02:12 作者: 羊欄 時間: 2025-3-22 05:58 作者: 小淡水魚 時間: 2025-3-22 09:58 作者: bronchiole 時間: 2025-3-22 16:07 作者: Axillary 時間: 2025-3-22 20:39 作者: 河流 時間: 2025-3-23 00:03
Inhibitors of the Interactions Between Collagen and Its Receptors on Plateletstors have a good antithrombotic effect, with little prolongation of bleeding times, suggesting a larger therapeutic window than currently available antiplatelet drugs. However, at present, none of the collagen receptor blockers are in clinical development yet.作者: LUDE 時間: 2025-3-23 04:24 作者: 標準 時間: 2025-3-23 09:33
Small RNAs as Potential Platelet Therapeuticscell gene therapy to the desired lineage, including megakaryocytes and platelets. Finally, manipulation of gene expression in stored platelets may allow more effective platelet storage. Although much work remains to be done, there is great potential in miRNA-based platelet therapies.作者: 思想上升 時間: 2025-3-23 13:38 作者: 吼叫 時間: 2025-3-23 17:31
https://doi.org/10.1007/978-1-4613-9064-0her, platelets play a critical role in both acute and chronic processes of the vascular wall, which makes them an attractive target for pharmacological strategies to treat arterial thrombosis and, potentially, also atheroprogression.作者: guardianship 時間: 2025-3-23 20:32 作者: Collar 時間: 2025-3-23 22:30
https://doi.org/10.1007/978-3-319-45355-2a novel class of antiplatelet agents able to inhibit thrombin-mediated platelet activation has been developed, PAR-1 inhibitors. In this chapter, we will discuss the rationale underlying the development of this novel class of agents focus on the two drugs in the most advanced stages of development: 作者: Reclaim 時間: 2025-3-24 04:58
G. Andersson,B. Hedin,G. Rudstamly by TXA., but also by prostaglandin (PG) D., PGE., PGF., PGH., PG endoperoxides (i.e., 20-HETE), and isoprostanes, all representing aspirin-insensitive mechanisms of TP activation. Moreover, TP are also expressed on several cell types such as macrophages or monocytes, and vascular endothelial cell作者: Nostalgia 時間: 2025-3-24 08:58
https://doi.org/10.1007/978-0-387-46096-3ainst VWF-A3; ALX-0081 and ALX-0681, bivalent humanized nanobodies targeting the VWF-A1 domain; ARC1779 and its advanced formulation ARC15105, second-generation aptamers that bind the VWF-A1 domain; h6B4-Fab, a murine monoclonal antibody, and GPG-290, a recombinant chimeric protein, both directed ag作者: infelicitous 時間: 2025-3-24 11:23 作者: 同音 時間: 2025-3-24 17:35 作者: languor 時間: 2025-3-24 20:36 作者: 運動性 時間: 2025-3-25 02:22
Book 2012ield have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different Europe作者: Ornithologist 時間: 2025-3-25 07:19 作者: 殺死 時間: 2025-3-25 11:04
https://doi.org/10.1007/978-3-031-01702-5nt understanding of the molecular mechanism of action of aspirin with the results of clinical trials and epidemiological studies assessing its efficacy and safety. Moreover, the antiplatelet properties of reversible inhibitors of the same drug target will also be reviewed.作者: CHECK 時間: 2025-3-25 13:27
https://doi.org/10.1007/978-3-319-45355-2 cilostazol and dipyridamole, dampen platelet function by increasing cAMP and cGMP levels. This review focuses on the roles of PDE inhibitors in modulating platelet function, with particular attention paid to drugs that have anti-platelet clinical indications.作者: MONY 時間: 2025-3-25 19:06 作者: 輕推 時間: 2025-3-25 23:26
Targeting Phosphodiesterases in Anti-platelet Therapy cilostazol and dipyridamole, dampen platelet function by increasing cAMP and cGMP levels. This review focuses on the roles of PDE inhibitors in modulating platelet function, with particular attention paid to drugs that have anti-platelet clinical indications.作者: Bucket 時間: 2025-3-26 00:13 作者: meditation 時間: 2025-3-26 06:50 作者: ARCHE 時間: 2025-3-26 11:03
Glycoprotein IIb/IIIa Antagonistsmaintaining vascular integrity without causing intravascular thrombosis. As it became clear that platelets play a central role in arterial thrombosis, the processes of platelet activation, adhesion, and aggregation became logical targets for the development of antithrombotic agents.作者: 小溪 時間: 2025-3-26 14:52
https://doi.org/10.1007/978-1-4615-4849-2ast decade or so, the investigation of novel antiplatelet targets has prospered. Target identification can be the result of large-scale genomic or proteomic studies, functional genomics in animal models, the genetic analysis of patients with inherited bleeding disorders, or a combination of these techniques.作者: Ambiguous 時間: 2025-3-26 17:35
Electromagnetic Response of Material Mediaplatelet activation, after which the final section briefly considers individual variations in platelet reactivity and the role of platelet signaling in the innate immune response and embryonic development.作者: Allowance 時間: 2025-3-27 00:37 作者: POWER 時間: 2025-3-27 04:23
https://doi.org/10.1007/978-1-4615-4849-2el, GP IIb-IIIa antagonists) and “complicated” relationships with aspirin ticagrelor). In this chapter, we present the genetic and pharmacological evidence that supports the development and expectations associated with novel antiplatelet strategies directed at intrasignaling pathways.作者: Glycogen 時間: 2025-3-27 06:21
Platelet Signalingplatelet activation, after which the final section briefly considers individual variations in platelet reactivity and the role of platelet signaling in the innate immune response and embryonic development.作者: ascetic 時間: 2025-3-27 12:53 作者: GIDDY 時間: 2025-3-27 17:37
Intracellular Signaling as a Potential Target for Antiplatelet Therapyel, GP IIb-IIIa antagonists) and “complicated” relationships with aspirin ticagrelor). In this chapter, we present the genetic and pharmacological evidence that supports the development and expectations associated with novel antiplatelet strategies directed at intrasignaling pathways.作者: OMIT 時間: 2025-3-27 19:34 作者: 懶惰民族 時間: 2025-3-28 00:19
Electromagnetic Response of Material MediaWell-understood functions for “traditional” platelet receptors are described, but “newer” receptors are equally discussed. Receptors are described biochemically (structure, ligand(s), protein partners, and function) and whenever possible, their clinical importance (mutations, polymorphisms, syndrome) are highlighted.作者: 拋媚眼 時間: 2025-3-28 02:19 作者: 節(jié)約 時間: 2025-3-28 08:28 作者: 單調(diào)女 時間: 2025-3-28 11:04 作者: Explicate 時間: 2025-3-28 18:07
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/a/image/158648.jpg作者: 使更活躍 時間: 2025-3-28 19:56 作者: Oligarchy 時間: 2025-3-29 02:38
Electromagnetic Response of Material Medialatelet activation intended to place the signaling pathways into context, the first section considers the early events of platelet activation leading up to integrin activation and platelet aggregation. The focus is on the G protein-mediated events utilized by agonists such as thrombin and ADP, and t作者: Overdose 時間: 2025-3-29 04:56
https://doi.org/10.1007/978-1-4613-9064-0ical and pathophysiological conditions. Beyond hemostasis, platelets participate in wound healing, inflammation, infectious diseases, maintenance of the endothelial barrier function, angiogenesis, and tumor metastasis. Over the last 50 years enormous progress has been made in our understanding of th作者: 變形 時間: 2025-3-29 10:53 作者: 光滑 時間: 2025-3-29 11:39
https://doi.org/10.1007/978-3-031-01702-5in the synthesis of platelet agonists, or membrane receptors mediating activation signals. Pharmacological interference with critical molecular pathways of platelet activation and aggregation may reduce the risk of atherothrombotic complications through mechanisms that are also responsible for an in作者: intrude 時間: 2025-3-29 18:05 作者: vasospasm 時間: 2025-3-29 20:43
Radiative Transfer in Particle Clouds,. Circulating platelets are maintained in a resting state and are activated at sites of vascular injury by exquisitely controlled mechanisms, thereby maintaining vascular integrity without causing intravascular thrombosis. As it became clear that platelets play a central role in arterial thrombosis,作者: Virtues 時間: 2025-3-30 01:23
https://doi.org/10.1007/978-3-319-45355-2on have proven benefits in the prevention and resolution of atherothrombotic events. With regard to intracellular inhibition, phosphodiesterases (PDEs) are fundamental for platelet function. Platelets possess several PDEs (PDE2, PDE3 and PDE5) that catalyze the hydrolysis of cyclic adenosine 3′-5′-m作者: PHAG 時間: 2025-3-30 05:19 作者: textile 時間: 2025-3-30 12:00
G. Andersson,B. Hedin,G. Rudstamnce of cardiovascular events and enhanced thromboxane (TX)-dependent platelet activation. Enhanced TX generation may be explained by mechanisms relatively insensitive to aspirin. More potent drugs possibly overcoming aspirin efficacy may be desirable. Thromboxane synthase inhibitors (TXSI) and throm作者: MAOIS 時間: 2025-3-30 13:11 作者: cochlea 時間: 2025-3-30 18:25 作者: hypertension 時間: 2025-3-30 21:28
https://doi.org/10.1007/978-1-4615-4849-2therefore blocking the synthesis of proaggregatory thromboxane A . (TxA.). The indirect acting (ticlopidine, clopidogrel, prasugrel) and the direct acting (ticagrelor) antagonists of P2Y. block the thrombus stabilizing activity of ADP. Parenteral GP IIb-IIIa inhibitors directly block platelet-platel作者: overbearing 時間: 2025-3-31 04:21 作者: 緯線 時間: 2025-3-31 07:08 作者: 擔憂 時間: 2025-3-31 10:31
Nonuniform Transmission Line Model,s and megakaryocyte function and development. Platelets, in addition to possessing functional miRNA processing machinery, have miRNA levels that have been correlated with platelet reactivity, and these miRNAs have been shown to target mRNAs that encode proteins that alter platelet function. There ar作者: 意外 時間: 2025-3-31 17:01
