標題: Titlebook: Antineoplastic and Immunosuppressive Agents; Part I Alan C. Sartorelli (Professor),David G. Johns Book 1974 Springer-Verlag Berlin · Heidel [打印本頁] 作者: 次要 時間: 2025-3-21 17:35
書目名稱Antineoplastic and Immunosuppressive Agents影響因子(影響力)
書目名稱Antineoplastic and Immunosuppressive Agents影響因子(影響力)學科排名
書目名稱Antineoplastic and Immunosuppressive Agents網(wǎng)絡公開度
書目名稱Antineoplastic and Immunosuppressive Agents網(wǎng)絡公開度學科排名
書目名稱Antineoplastic and Immunosuppressive Agents被引頻次
書目名稱Antineoplastic and Immunosuppressive Agents被引頻次學科排名
書目名稱Antineoplastic and Immunosuppressive Agents年度引用
書目名稱Antineoplastic and Immunosuppressive Agents年度引用學科排名
書目名稱Antineoplastic and Immunosuppressive Agents讀者反饋
書目名稱Antineoplastic and Immunosuppressive Agents讀者反饋學科排名
作者: 一再困擾 時間: 2025-3-21 21:48
Adsorption and Catalysis on Ionic Solids, activity; the practical impetus toward the study of the latter group of reactions has been the possibility of developing specific inhibitors of such catabolic inactivation, thus increasing the potency and duration of action of the parent form of the drug.作者: Interregnum 時間: 2025-3-22 01:52 作者: 難取悅 時間: 2025-3-22 06:26
An Overview to Electrochemistry,exclusive, as pointed out by . and . (1955), . and . (1957), . (1970), and others. Agents that are mutagenic, in some cases the anticancer drug itself, may increase the probability of the development of resistance by increasing the mutation frequency in a population of treated cells.作者: rectum 時間: 2025-3-22 09:56 作者: indifferent 時間: 2025-3-22 12:59 作者: 不開心 時間: 2025-3-22 19:45
Theoretical Considerations in the Chemotherapy of Brain Tumorser. For this reason, not only demonstrated antitumor activity, but also a knowledge of the physical and chemical properties of the drug and the anatomical and physiological characteristics of blood-tissue exchange for brain and brain tumors helps to predict more precisely which compounds will be effective against brain tumors.作者: 不如樂死去 時間: 2025-3-23 00:53 作者: 觀點 時間: 2025-3-23 04:39
0171-2004 formation on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the prese作者: 安慰 時間: 2025-3-23 05:42
Electrochemical Crystal Growth,he chemotherapeutic approach to oncology has been rather empirical with the major successes being noted with drugs which are generally more toxic to rapidly proliferating cells. Most of these cytotoxic anticancer agents act primarily as inhibitors of nucleic acid synthesis at various sites and by different mechanisms.作者: 下邊深陷 時間: 2025-3-23 10:42
Fused Salt Electrolysis and Electrothermicsllular processes. No exploitable unique biochemical processes have been discovered which make neoplastic cells more sensitive to chemotherapeutic agents than dividing normal cells. The selectivity of most antineoplastic agents depends, in part at least, upon particular differences in cell growth kinetics and pharmacologic effects of drug exposure.作者: 中和 時間: 2025-3-23 15:43
Electrodeposition and Surface Finishing neoplastic disease, demonstrates that such selectivity can be achieved even in man. However, the large number of patients who still die of malignant disease testify that selectivity of drug action is not attained with sufficient frequency or reliability.作者: 集中營 時間: 2025-3-23 18:46
Rational Design of Pyrimidine Nucleoside Analogshe chemotherapeutic approach to oncology has been rather empirical with the major successes being noted with drugs which are generally more toxic to rapidly proliferating cells. Most of these cytotoxic anticancer agents act primarily as inhibitors of nucleic acid synthesis at various sites and by different mechanisms.作者: 不知疲倦 時間: 2025-3-24 00:36 作者: 樂章 時間: 2025-3-24 04:54 作者: 溺愛 時間: 2025-3-24 08:32 作者: URN 時間: 2025-3-24 13:06
Book 1974on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handboo作者: glacial 時間: 2025-3-24 15:49
Electrochemical Crystal Growth,f folate biochemistry, and second, by consideration of new areas of considerable promise, more truly rational approaches will be discussed which could greatly enhance the therapeutic utility of these agents.作者: GEAR 時間: 2025-3-24 21:42 作者: Orthodontics 時間: 2025-3-25 00:27
Rational Design of Folic Acid Antagonistsf folate biochemistry, and second, by consideration of new areas of considerable promise, more truly rational approaches will be discussed which could greatly enhance the therapeutic utility of these agents.作者: OPINE 時間: 2025-3-25 03:57
Transport of Antineoplastic Agentsere within the cell. A notable exception is provided by asparaginase, which, without entering the cells, causes a critical deficiency of asparagine by cleaving it extracellularly to aspartic acid (., 1968; . et al., 1971).作者: 暫時別動 時間: 2025-3-25 07:38
Absorption, Distribution, and Excretion of Antineoplastic and Immunosuppressive Agents processes which regulate the response of an organism to several commonly used antineoplastic and immunosuppressive agents. Excluded is the more complex process of metabolism since this aspect of pharmacological disposition is considered in two later chapters, and also in the chapters dealing with individual agents.作者: 小說 時間: 2025-3-25 13:28 作者: Spinous-Process 時間: 2025-3-25 16:12
Antineoplastic and Immunosuppressive Agents978-3-642-65678-1Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: CRANK 時間: 2025-3-25 20:05 作者: Exploit 時間: 2025-3-26 02:19
https://doi.org/10.1007/b113784other relates to the dynamic characteristics of cell populations, including rates of cell proliferation, of cell migration, and of cell death, and the changes in these parameters involved in tissue response to injury.作者: construct 時間: 2025-3-26 04:23 作者: DAFT 時間: 2025-3-26 12:29
https://doi.org/10.1007/978-3-642-65678-1Immunsuppression; Krebs; Strahlentherapie; Zytostatikum; agents; therapy作者: 表狀態(tài) 時間: 2025-3-26 13:08
978-3-642-65680-4Springer-Verlag Berlin · Heidelberg 1974作者: 法官 時間: 2025-3-26 20:39 作者: 偽書 時間: 2025-3-26 21:54 作者: 去才蔑視 時間: 2025-3-27 01:30 作者: Infant 時間: 2025-3-27 07:46
https://doi.org/10.1007/b113784tially sensitive to chemotherapy, either in the sense that a sizeable number of patients show some degree of regression of disease, or that a few patients will show a substantial degree of regression. There are now over 30 drugs that are available for the chemotherapy of cancer. Even though some of 作者: right-atrium 時間: 2025-3-27 10:41
Stochastic Approach to Nucleation,ainst clinical neoplasia, (b) the detailed investigation of the action of drugs on host-tumor parameters and of factors which may influence chemotherapeutic effectiveness, and (c) detailed pharmacologic, toxicologic, biochemical, virologic, immunologic, and other investigations of the basic mechanis作者: harangue 時間: 2025-3-27 14:51
Kinetics of Electrochemical Nucleation,98), and the application of this class of compounds to the treatment of human cancers was introduced by . and . (1946). This followed the observation that derivatives of mustard gas such as HN2 (nitrogen mustard, I) were particularly toxic towards lymphoid tissue . and led to the use of such agents 作者: 陳腐思想 時間: 2025-3-27 18:55 作者: Arable 時間: 2025-3-28 01:46
Electrochemical Crystal Growth,the invading cancer cells. Although much is known about the biologic activity of certain agents, such as 6-mercaptopurine and 6-thioguanine, the basis of their selective action on cancer cells is still not fully understood. This selectivity could result from greater catabolism of the drug by normal 作者: 粗糙濫制 時間: 2025-3-28 04:04 作者: Foreknowledge 時間: 2025-3-28 09:54 作者: 不可侵犯 時間: 2025-3-28 13:26 作者: 譏諷 時間: 2025-3-28 15:18
Fused Salt Electrolysis and Electrothermics the research in this area of biology has undergone rapid change. The cell cycle is no longer regarded naively as a period of steady uniform growth between one cell division and the next. Instead, observations have led us to regard the growth and division of cells as a series of ordered chemical cha作者: Acquired 時間: 2025-3-28 19:23
Feasibility of Electrochemical Processes66) and his collaborators (. et al., 1966, 1969) comparing rapidly dividing transplantable murine lymphoma cells with essentially “resting” normal bone marrow cells, both of which form colonies in the spleen, showed that some lethal agents may be regarded as cell cycle specific, or even phase specif作者: DNR215 時間: 2025-3-29 01:56
Fused Salt Electrolysis and Electrothermics manner and site of administration, (c) the nature of the drug’s absorption, distribution, and metabolism, and (d) the interaction of the drug with cellular processes. No exploitable unique biochemical processes have been discovered which make neoplastic cells more sensitive to chemotherapeutic agen作者: ENDOW 時間: 2025-3-29 06:09
Thermodynamics of Electrochemical Processesineoplastic and immunosuppressive agents. Thus, the interrelated mechanisms of absorption, binding, distribution, metabolism, and excretion are the chief factors that determine the effective concentration of a drug at a receptor site (Fig. 1). In this chapter, a brief consideration is given to those作者: 成績上升 時間: 2025-3-29 10:41 作者: GROSS 時間: 2025-3-29 15:03
Adsorption and Catalysis on Ionic Solids,. The former group of reactions includes such transformations as conversion of purine and pyrimidine analogs, to their pharmacologically active nucleotide forms and incorporation of the latter into nucleic acids. Because of their immediate relevance to the antitumor activity of these agents, and als作者: monologue 時間: 2025-3-29 19:01 作者: Nucleate 時間: 2025-3-29 22:53 作者: 優(yōu)雅 時間: 2025-3-30 03:37 作者: Malfunction 時間: 2025-3-30 07:59 作者: Induction 時間: 2025-3-30 10:43 作者: curriculum 時間: 2025-3-30 15:25
0171-2004 at ever-increasing rates from experimental tumor screening systems maintained by a variety of private and governmental laboratories through- out the world. At t978-3-642-65680-4978-3-642-65678-1Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: 油膏 時間: 2025-3-30 20:06
Agents of Choice in Neoplastic Diseaseug — a body of knowledge that is evolving rather dynamically. This chapter is written with the objective of providing a general framework for the detailed discussions to follow, so that the reader, should he have the need, may find an orientation to current usage of antitumor drugs. With this in min作者: Bereavement 時間: 2025-3-31 00:25
Rational Design of Alkylating Agentsing cells, and testicular and ovarian tissues are also damaged. The cancer chemotherapist has the problem of modifying the structure of the so-called biological alkylating agents in such a way as to render them specifically cytotoxic towards neoplastic tissue.作者: 協(xié)奏曲 時間: 2025-3-31 03:32 作者: 失眠癥 時間: 2025-3-31 05:24
Site of Action of Cytotoxic Agents in the Cell Life Cycle to the problem of designing treatment schedules for malignant disease (.. et al., 1965; ., 1965; . et al., 1967; ., 1968; for example) spurred much research towards defining which agents exert their lethal effect at which phase of the cell generation cycle, that is in .., ., .., or . as defined in 作者: 的染料 時間: 2025-3-31 09:55 作者: 禮節(jié) 時間: 2025-3-31 15:10
The Constancy of the Product of Concentration and Timeighting reflex was restored. Similar observations with respect to brain levels were made in rats and guinea pigs, and in all four species serum levels were a reflection of brain drug levels. He also reported that carisoprodol had a 10-fold spread in duration of action in various animal species, but 作者: 非秘密 時間: 2025-3-31 19:30 作者: LOPE 時間: 2025-4-1 00:50 作者: VALID 時間: 2025-4-1 02:18
Kinetics of Electrochemical Nucleation,ing cells, and testicular and ovarian tissues are also damaged. The cancer chemotherapist has the problem of modifying the structure of the so-called biological alkylating agents in such a way as to render them specifically cytotoxic towards neoplastic tissue.作者: aggressor 時間: 2025-4-1 07:54
