標(biāo)題: Titlebook: Antimutagenesis and Anticarcinogenesis Mechanisms III; Giorgio Bronzetti,Hikoya Hayatsu,Claire Wilson & A Book 1993 Springer Science+Busin [打印本頁(yè)] 作者: 調(diào)停 時(shí)間: 2025-3-21 16:38
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III影響因子(影響力)
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III影響因子(影響力)學(xué)科排名
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III被引頻次
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III被引頻次學(xué)科排名
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III年度引用
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III年度引用學(xué)科排名
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III讀者反饋
書(shū)目名稱Antimutagenesis and Anticarcinogenesis Mechanisms III讀者反饋學(xué)科排名
作者: 免除責(zé)任 時(shí)間: 2025-3-21 22:57
Multiple Mechanisms: The Example of Vitamin Ashown to be prevented by retinoids, which in this organ function as antitumor promoters in the two-stage system using 7,12-dimethylbenz(a)anthracene (DMBA) as the initiator, and 12-tetradecanoyl-phorboll3-acetate (TPA) as tumor promoter. Even though pharmacological doses applied topically appear to 作者: 挑剔為人 時(shí)間: 2025-3-22 01:11 作者: 高貴領(lǐng)導(dǎo) 時(shí)間: 2025-3-22 04:47
Protective Mechanisms of Dietary Fibers in Nutritional Carcinogenesis action in carcinogenesis, classification into two broad types, soluble and insoluble fibers, is warranted. Soluble fibers are present in fruits, vegetables, and certain grains like oats. This type of fiber undergoes metabolism in the small intestine and especially in the large intestine through bac作者: Congestion 時(shí)間: 2025-3-22 11:09
Extracellular Interception of Mutagenss of defense against chemical mutagens/carcinogens. Kada and Shimoi (25) have classified molecules that function in this manner as “desmutagens,” and many of them are natural cellular metabolites (23). Among the specific mechanisms that such agents may employ are: prevention of the activation of “pr作者: Glucose 時(shí)間: 2025-3-22 14:21
Proteins as Scavengers of Nitrite: Antimutagenic Implicationsproduced from arginine in mammalian cells (9). Several epidemiological studies demonstrated that there is a good correlation between nitrate intake and gastric cancer mortality (4). It has been shown that various mutagenic or carcinogenic compounds are produced from food components by reactions with作者: Spinous-Process 時(shí)間: 2025-3-22 19:57 作者: justify 時(shí)間: 2025-3-22 22:16 作者: 極深 時(shí)間: 2025-3-23 03:19
Extrapolation of in Vitro Antimutagenicity to the in Vivo Situation: The Case for Anthraflavic Acid Ames Salmonella/microsome test as the biological endpoint. Various plant compounds or extracts are incorporated into the postmitochondrial (S9) activation system and their ability to inhibit the mutagenicity of model precarcinogens is determined. However, such a protocol suffers from a number of ma作者: 白楊魚(yú) 時(shí)間: 2025-3-23 08:58 作者: Intractable 時(shí)間: 2025-3-23 10:28
Antimutagenic Investigations on Commercial Yogurt human stomach cancer induced by alkylating agents (6). Human subjects (7) and experimental animals (8) receiving dietary supplements of . exhibited significantly lower levels of fecal enzymes associated with colon carcinogenesis. In addition, extracts prepared from ., ., and . spent media were show作者: Immunization 時(shí)間: 2025-3-23 15:07 作者: MEAN 時(shí)間: 2025-3-23 21:10 作者: angina-pectoris 時(shí)間: 2025-3-23 23:19 作者: chance 時(shí)間: 2025-3-24 06:09
Sulfotransferase- and Acetyltransferase-Mediated Activation of Carcinogenic N-Hydroxyarylamines in Mological macromolecules, most arylamines are activated by two successive reactions, N-oxidation and O-esterification, to form their reactive intermediates. The former reaction is catalyzed mainly by microsomal cytochrome P-450, while the latter is mediated by cytosolic transferases in the liver. Amo作者: CAMEO 時(shí)間: 2025-3-24 07:24
Induction of Rat Liver GSH Transferases by 1,2-Dithiole-3-Thione Illustrates Both Anticarcinogenic aic GSH and several GSH-dependent enzymes including GSH transferases (GSTs) (2,14) that catalyze the detoxification of aflatoxin B.-8,9-oxide, the ultimate carcinogen. We had previously concluded (5) that in phenobarbitol-induced rat liver, GSTs 1-1 and 1-2 are most important among soluble GSTs in th作者: 相符 時(shí)間: 2025-3-24 10:53
Organ-Specific Modification of Carcinogenesis by Antioxidants in Ratscond- stage forestomach and urinary bladder carcinogenesis in rats pretreated with carcinogens, but inhibits liver, lung, and mammary carcinogenesis (13). BHA at high doses rapidly induces cell proliferation and an increase in DNA synthesis in the forestomach epithelium of both rats and hamsters, th作者: graphy 時(shí)間: 2025-3-24 15:58
The Modulating Effects of Antioxidants in Rat Embryos and Sertoli Cells in Culturedulating effects of antioxidants in such systems..Enzymically generated oxygen radicals have been shown to be toxic and/or mutagenic in a variety of in vitro test systems. It is known that vitamins C and E can modify responses in such systems..Malformations and growth reductions have been observed i作者: Aids209 時(shí)間: 2025-3-24 20:17
Blocking the Plant Activation of Promutagenic Aromatic Amines by Peroxidase Inhibitorsns (20,30). Plant activation is the process by which a promutagen is activated into a mutagen by a plant system (18). A promutagen is a chemical that is not mutagenic in itself but can be biologically transformed into a mutagen. The capability of plants to bioconcentrate environmental agents and act作者: Dawdle 時(shí)間: 2025-3-24 23:36
https://doi.org/10.1007/978-3-319-10843-8ly related to estimated amounts of vegetable consumption. Initially, we screened approximately eighty different edible plants and found that antimutagenicity against furyl furamide (AF2) was widely distributed in vegetables.作者: 不自然 時(shí)間: 2025-3-25 04:16
Inhibitory Effects of Dietary Leafy Vegetables on Mutagens and on Active Oxygensly related to estimated amounts of vegetable consumption. Initially, we screened approximately eighty different edible plants and found that antimutagenicity against furyl furamide (AF2) was widely distributed in vegetables.作者: HERTZ 時(shí)間: 2025-3-25 11:27
Basic Life Scienceshttp://image.papertrans.cn/a/image/158626.jpg作者: Enteropathic 時(shí)間: 2025-3-25 12:20
Fritz Scholz,Uwe Schr?der,Rubin Gulaboskiic mass. Similar concepts may hold true for other mutation-related conditions and, in general, for those chronico-degenerative diseases having a multifactorial origin, a multistep pathogenesis, and a long latency period. Keeping in mind that the neoplastic mass is of monoclonal origin, and assuming 作者: opinionated 時(shí)間: 2025-3-25 18:01 作者: Contracture 時(shí)間: 2025-3-25 21:31
https://doi.org/10.1007/b137048 amino precursors in the body. Activated macrophages and bacterial strains isolated from human infections can enzymatically produce nitrosating agents and NOC from precursors at neutral pH. As a consequence, endogenous nitrosation may occur at various sites of the body, such as the oral cavity, stom作者: CRACY 時(shí)間: 2025-3-26 03:16
https://doi.org/10.1007/b137048 action in carcinogenesis, classification into two broad types, soluble and insoluble fibers, is warranted. Soluble fibers are present in fruits, vegetables, and certain grains like oats. This type of fiber undergoes metabolism in the small intestine and especially in the large intestine through bac作者: Medley 時(shí)間: 2025-3-26 06:19
https://doi.org/10.1007/b137048s of defense against chemical mutagens/carcinogens. Kada and Shimoi (25) have classified molecules that function in this manner as “desmutagens,” and many of them are natural cellular metabolites (23). Among the specific mechanisms that such agents may employ are: prevention of the activation of “pr作者: novelty 時(shí)間: 2025-3-26 11:29 作者: Myofibrils 時(shí)間: 2025-3-26 14:24
Fritz Scholz,Uwe Schr?der,Rubin Gulaboskiqual interest is whether such compounds have antitumor, antiviral, or antimutagenic properties. For example, the highly active antitumor agents, camptothecin and taxol, have been isolated from the bark and wood of trees (13,21), and another active agent, bryostatin I, from a marine animal (11). Dudl作者: Barrister 時(shí)間: 2025-3-26 20:50 作者: Instinctive 時(shí)間: 2025-3-26 21:23
https://doi.org/10.1007/978-3-319-10843-8 Ames Salmonella/microsome test as the biological endpoint. Various plant compounds or extracts are incorporated into the postmitochondrial (S9) activation system and their ability to inhibit the mutagenicity of model precarcinogens is determined. However, such a protocol suffers from a number of ma作者: Bravura 時(shí)間: 2025-3-27 01:58
Su-Il Pyun,Heon-Cheol Shin,Joo-Young Gont I: Rats received dietary administration of magnesium hydroxide at concentrations of 500 or 1,000 ppm after treatment with methylazoxymethanol (MAM) acetate (25 mg/kg, 3 times). These rats had a lower incidence of large bowel neoplasms than animals given MAM acetate alone. Reduction of the tumor i作者: Anonymous 時(shí)間: 2025-3-27 08:29 作者: 無(wú)能性 時(shí)間: 2025-3-27 11:15 作者: 油氈 時(shí)間: 2025-3-27 17:04
https://doi.org/10.1007/978-3-642-03967-6eria (3,27). GSH is characterized by its reactive thiol group and its γ-glutamyl bond which makes it resistant to normal peptidase activity. In mammalian cells, the concentration of GSH is often very high (in the millimolar range); most of the intracellular GSH exists in the thiol form, although mix作者: hemophilia 時(shí)間: 2025-3-27 17:55
Delphine Schaming,Laurent Ruhlmannlex mixture, such as diesel extract, has been analyzed. Studies have been carried out in vitro with the Ames test (reverse mutations on TA98, TA100, and TA104 strains) and sister chromatid exchanges assay (SCE) in human lymphocytes. NAC inhibits diesel genotoxicity in both assays. NAC also inhibits 作者: cauda-equina 時(shí)間: 2025-3-27 23:54 作者: Conscientious 時(shí)間: 2025-3-28 04:26
Spectroelectrochemistry of Phthalocyanines,ic GSH and several GSH-dependent enzymes including GSH transferases (GSTs) (2,14) that catalyze the detoxification of aflatoxin B.-8,9-oxide, the ultimate carcinogen. We had previously concluded (5) that in phenobarbitol-induced rat liver, GSTs 1-1 and 1-2 are most important among soluble GSTs in th作者: mutineer 時(shí)間: 2025-3-28 09:27 作者: interference 時(shí)間: 2025-3-28 14:12
Justus Masa,Edgar Ventosa,Wolfgang Schuhmanndulating effects of antioxidants in such systems..Enzymically generated oxygen radicals have been shown to be toxic and/or mutagenic in a variety of in vitro test systems. It is known that vitamins C and E can modify responses in such systems..Malformations and growth reductions have been observed i作者: 模仿 時(shí)間: 2025-3-28 17:23
Electrochemistry of Semiconductorsns (20,30). Plant activation is the process by which a promutagen is activated into a mutagen by a plant system (18). A promutagen is a chemical that is not mutagenic in itself but can be biologically transformed into a mutagen. The capability of plants to bioconcentrate environmental agents and act作者: WAX 時(shí)間: 2025-3-28 21:39 作者: AVID 時(shí)間: 2025-3-29 01:49
978-1-4613-6299-9Springer Science+Business Media New York 1993作者: Acumen 時(shí)間: 2025-3-29 03:04
https://doi.org/10.1007/978-3-642-03967-6of intracellular GSH is found in the cytosol, but the existence of minor mitochondrial and nuclear pools of GSH has been demonstrated. Moreover, both GSH and GSSG are present in various body fluids, including plasma, bile, and the glomerular filtrate, although at much lower concentrations.作者: 阻擋 時(shí)間: 2025-3-29 07:23 作者: crutch 時(shí)間: 2025-3-29 12:32 作者: Autobiography 時(shí)間: 2025-3-29 17:39 作者: 乳白光 時(shí)間: 2025-3-29 22:19
sion, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (作者: 側(cè)面左右 時(shí)間: 2025-3-30 02:17 作者: ATP861 時(shí)間: 2025-3-30 05:00
https://doi.org/10.1007/978-3-642-29464-8ignificantly lower levels of fecal enzymes associated with colon carcinogenesis. In addition, extracts prepared from ., ., and . spent media were shown to inhibit the growth of Sarcoma and Ehrlich tumors, suggesting that lactobacillic cultures have an antitumorigenic effect (9,10).作者: 不近人情 時(shí)間: 2025-3-30 08:33 作者: 痛恨 時(shí)間: 2025-3-30 16:17 作者: TSH582 時(shí)間: 2025-3-30 20:10 作者: 招募 時(shí)間: 2025-3-30 22:27
Blocking the Plant Activation of Promutagenic Aromatic Amines by Peroxidase Inhibitorsis not mutagenic in itself but can be biologically transformed into a mutagen. The capability of plants to bioconcentrate environmental agents and activate promutagens into toxic metabolites is significant when one realizes the immense diversity of xenobiotics to which plants are intentionally and unintentionally exposed.作者: 下級(jí) 時(shí)間: 2025-3-31 02:23
Book 1993stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,6作者: condescend 時(shí)間: 2025-3-31 05:29 作者: 拍翅 時(shí)間: 2025-3-31 12:33
Proteins as Scavengers of Nitrite: Antimutagenic Implicationseans and Chinese cabbage. Diazoquinones are produced from phenolics in smoked foods, soy sauce, and medical drugs. It is well known that nitrosamines are carcinogenic after absorption and metabolic activation. Nitrosoindoles and diazoquinones have been found to be direct-acting for Salmonella bacteria.作者: orient 時(shí)間: 2025-3-31 15:03
Antimutagenic Agents from Natural Products of Terrestrial and Marine Originey Williams has proposed that “secondary metabolites are a measure of the fitness of the organism to survive by repelling or entrapping other organisms” (23). Mitscher has stated that “as some constituents of higher plants are mutagens, it seems reasonable that substances capable of antimutagenicity also be produced by such plants” (10).作者: Osteoporosis 時(shí)間: 2025-3-31 19:05
Fritz Scholz,Uwe Schr?der,Rubin Gulaboskiey Williams has proposed that “secondary metabolites are a measure of the fitness of the organism to survive by repelling or entrapping other organisms” (23). Mitscher has stated that “as some constituents of higher plants are mutagens, it seems reasonable that substances capable of antimutagenicity also be produced by such plants” (10).作者: forthy 時(shí)間: 2025-3-31 22:14 作者: Inscrutable 時(shí)間: 2025-4-1 03:54 作者: 我要沮喪 時(shí)間: 2025-4-1 08:17
https://doi.org/10.1007/b137048 serves as substrate for the nitrosating species. Independently, epidemiological studies have already established that fresh fruits and vegetables that are sources of vitamin C, other vitamins, and polyphenols have a protective effect against cancers at various sites and in particular gastric cancer作者: Urea508 時(shí)間: 2025-4-1 12:18 作者: 創(chuàng)作 時(shí)間: 2025-4-1 15:29
https://doi.org/10.1007/b137048nd other recent examples in the literature, several examples of mechanistic approaches to these studies using natural plant-derived materials, e.g., humic acid, . extract, glutathione, and bioflavonoids, are also described. Antioxidants and agents that conjugate electrophiles will be among the modes
