標題: Titlebook: Antibody Engineering Protocols; Sudhir Paul Book 1995 Humana Press 1995 [打印本頁] 作者: 一再 時間: 2025-3-21 19:31
書目名稱Antibody Engineering Protocols影響因子(影響力)
書目名稱Antibody Engineering Protocols影響因子(影響力)學科排名
書目名稱Antibody Engineering Protocols網絡公開度
書目名稱Antibody Engineering Protocols網絡公開度學科排名
書目名稱Antibody Engineering Protocols被引頻次
書目名稱Antibody Engineering Protocols被引頻次學科排名
書目名稱Antibody Engineering Protocols年度引用
書目名稱Antibody Engineering Protocols年度引用學科排名
書目名稱Antibody Engineering Protocols讀者反饋
書目名稱Antibody Engineering Protocols讀者反饋學科排名
作者: Implicit 時間: 2025-3-21 20:56 作者: spondylosis 時間: 2025-3-22 03:42 作者: 愛得痛了 時間: 2025-3-22 08:24 作者: 阻撓 時間: 2025-3-22 10:16 作者: 密碼 時間: 2025-3-22 13:30 作者: Prostaglandins 時間: 2025-3-22 18:38
https://doi.org/10.1007/978-3-322-86537-3 stringent conditions and, therefore, are easy to isolate and manipulate. These advantages have provoked considerable interest in the idea that new catalytic antibodies could substitute for enzymes in therapy.作者: Gustatory 時間: 2025-3-22 23:47 作者: 卡死偷電 時間: 2025-3-23 04:44
DNA Hydrolysis by Antibodies, stringent conditions and, therefore, are easy to isolate and manipulate. These advantages have provoked considerable interest in the idea that new catalytic antibodies could substitute for enzymes in therapy.作者: 啟發(fā) 時間: 2025-3-23 09:08 作者: 忘恩負義的人 時間: 2025-3-23 12:04 作者: 靈敏 時間: 2025-3-23 15:25 作者: 玉米 時間: 2025-3-23 21:44
Jo Reichertz,Carina Jasmin Englertetermine protein structure, stability, and interaction properties ultimately arise from the distances that separate the various types of atoms involved, including proteins, ligands, and solvent molecules.作者: Cupping 時間: 2025-3-24 02:14
Einführung in die qualitative Videoanalysest 7 families. V. gene members within a given family are highly homologous with >80% sequence identity, whereas the degree of homology between members of distinct families is usually <70%. Human V. families vary in size ranging from one member in the V.6 family to over 30 in the V.3 family (.).作者: 老人病學 時間: 2025-3-24 06:01 作者: Mawkish 時間: 2025-3-24 08:17 作者: morale 時間: 2025-3-24 10:58
Crystallographic and Chromatographic Methods for Study of Antibody Light Chains and Other Proteins,etermine protein structure, stability, and interaction properties ultimately arise from the distances that separate the various types of atoms involved, including proteins, ligands, and solvent molecules.作者: BOAST 時間: 2025-3-24 15:49
Detection of Human Variable Gene Family Expression at the Single-Cell Level,st 7 families. V. gene members within a given family are highly homologous with >80% sequence identity, whereas the degree of homology between members of distinct families is usually <70%. Human V. families vary in size ranging from one member in the V.6 family to over 30 in the V.3 family (.).作者: gout109 時間: 2025-3-24 22:03 作者: 無可非議 時間: 2025-3-25 00:16 作者: minaret 時間: 2025-3-25 03:38
Preparation and Assay of Acetylcholinesterase Antibody,pproach consists of exploiting the internal image properties of anti-idiotypic antibodies to produce catalytic antibodies. In the first step, an antibody is raised that recognizes the active site of an enzyme. The binding site of this first antibody (Ab1) has structural features complementary to tho作者: HALL 時間: 2025-3-25 08:58 作者: 把手 時間: 2025-3-25 15:27 作者: 實施生效 時間: 2025-3-25 18:28
https://doi.org/10.1007/978-3-658-10327-9s cannot be diagnosed by the mere finding of increased titers of autoantibodies in serum. The question arises whether the structure, specificity, affinity, idiotypy, and genetics of autoantibodies in healthy subjects differ from those of pathological autoimmunity (.,.). Determining the fine specific作者: Lipoma 時間: 2025-3-25 20:19 作者: 小步舞 時間: 2025-3-26 02:07
Formale Soziologie (Beziehungslehre),pproach consists of exploiting the internal image properties of anti-idiotypic antibodies to produce catalytic antibodies. In the first step, an antibody is raised that recognizes the active site of an enzyme. The binding site of this first antibody (Ab1) has structural features complementary to tho作者: Institution 時間: 2025-3-26 06:44
https://doi.org/10.1007/978-3-476-02844-0lows the construction of a suitable mimic of the transition-state or other high-energy structures. Individual approaches explore the scope of the antibody’s enzymatic qualities and the validity of the design strategy for generating the catalyst. The success of these endeavors typically requires seve作者: Calculus 時間: 2025-3-26 11:27
,Praktische Hinweise und Lektürevorschl?ge,of the catalytic activity, we have cloned and expressed the light (L)-chain subunit and single-chain F. (scF.) fragment of one such antibody. The recombinant L chain and the scF. display interactions with VIP typical of an antibody-combining site. Both molecules are efficient catalysts (.). The dist作者: Ebct207 時間: 2025-3-26 15:22
Molecular Modeling of Antibody-Combining Sites,-ray crystallographic structures and good solution structures of free and antigen-bound antibodies. The number of reported antibody structures grows each year. Yet the number of structures deposited with the Brookhaven Protein Database (PDB) (.) remains relatively small, with 43 deposited entries at作者: 小卒 時間: 2025-3-26 18:24 作者: Cabinet 時間: 2025-3-26 22:29 作者: Condense 時間: 2025-3-27 03:37 作者: GUMP 時間: 2025-3-27 05:29 作者: Maximizer 時間: 2025-3-27 09:52
Evaluation of Antibody Clonality,e Burnet (.). This idea revolutionized the approach to formulation of experimental design in immunology. At the heart of clonal selection was the idea that antibody specificity preexisted before antigen arrival and that the antigen triggered the system by selecting only cells preprogrammed to make a作者: Intend 時間: 2025-3-27 16:21 作者: 大洪水 時間: 2025-3-27 21:24
Epitope and Idiotope Mapping Using Monoclonal Antibodies,ystem can recognize not only the antigens of the external environment, but also internal or self-antigens. Normal serum contains natural autoantibodies of the IgM and IgG classes that recognize a wide range of self-antigens, including nuclear antigens, intracellular and membrane components, and circ作者: 微不足道 時間: 2025-3-28 00:54
Anti-Idiotypic Antibodies That Mimic Opioids, thereafter, endogenous opioid peptides (endorphins) that also bound to these receptors were found in mammalian brain tissue. Subsequent pharmacological work revealed the existence of three main subclasses of receptors designated μ, δ, and κ. This work was confirmed by the recent cloning of these th作者: extinguish 時間: 2025-3-28 03:52 作者: 小官 時間: 2025-3-28 06:54
DNA Hydrolysis by Antibodies,bodies are ideally suited for therapeutic applications owing to their capability of homing to a particular target. In addition, they happily withstand stringent conditions and, therefore, are easy to isolate and manipulate. These advantages have provoked considerable interest in the idea that new ca作者: callous 時間: 2025-3-28 11:59 作者: 無聊的人 時間: 2025-3-28 18:32 作者: 形狀 時間: 2025-3-28 20:56 作者: eardrum 時間: 2025-3-29 01:31
Molecular Cloning of Antiground-State Proteolytic Antibody Fragments,biological functions of the constant regions. Rearrangement of variable-, diversity-, and joining-region genes and the hypermutability of the complementarity determining regions (CDRs) permit development of new antigen-binding specificities. With the discovery of natural catalytic activity in autoan作者: 收集 時間: 2025-3-29 04:53 作者: ARBOR 時間: 2025-3-29 08:39
1064-3745 Overview: 978-0-89603-275-0978-1-59259-538-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 遷移 時間: 2025-3-29 11:46
https://doi.org/10.1007/978-3-658-10327-9ity immunoblotting (.) has proven to be a powerful and high-resolution method for estimating clonality of immune responses to a variety of antigens. This chapter describes the affinity immunoblotting method in detail.作者: Bridle 時間: 2025-3-29 18:08 作者: 過去分詞 時間: 2025-3-29 23:14
https://doi.org/10.1007/978-3-476-02810-5We have been collecting nucleotide and amino acid sequences of proteins of immunological interest, and aligning them in order to understand the structure and function relations of these proteins (.). To aid in organizing and analyzing this collection, a computer program, called SEQHUNT, was written.作者: BROOK 時間: 2025-3-30 03:39
Konvexe Bewertungsringe und reelle Stellen,Antigen-binding sites in antibodies are formed by the variable regions of light (L) and heavy (H) chains. Delineation of antigen interactions with the individual subunits of antibodies is of interest for several reasons, including:作者: Carbon-Monoxide 時間: 2025-3-30 06:27
Manfred Knebusch,Claus ScheidererMajor advances in the analysis of biomolecular structure have emerged from the development of highly specific monoclonal antibodies (MAb) by K?hler and Milstein in 1975 (.). MAb are produced from hybridoma cell lines that secrete a single species of antibody to a unique antigen. The advantages of MAb as reagents for antibody engineering are:作者: harpsichord 時間: 2025-3-30 08:52 作者: Highbrow 時間: 2025-3-30 14:22
SEQHUNT,We have been collecting nucleotide and amino acid sequences of proteins of immunological interest, and aligning them in order to understand the structure and function relations of these proteins (.). To aid in organizing and analyzing this collection, a computer program, called SEQHUNT, was written.作者: 經典 時間: 2025-3-30 16:31 作者: Generator 時間: 2025-3-30 21:44 作者: 吸氣 時間: 2025-3-31 04:05 作者: 現(xiàn)暈光 時間: 2025-3-31 05:50 作者: 蛙鳴聲 時間: 2025-3-31 12:09
Einführung in die qualitative Videoanalyseantibody subunit free of the others. Thus, antibodies are singular proteins in that they are highly amenable to analysis by a fundamental scientific research strategy, i.e., investigation of complex systems by study of its parts. The metabolism of even a superficially simple bacterial cell cannot be作者: HUMP 時間: 2025-3-31 16:36
Jo Reichertz,Carina Jasmin Englertaffinity of an antibody, change the specificity of an enzyme, or to test a hypothesis regarding the role of a particular residue in determining structure or stability. The atomic coordinates determined by X-ray crystallography or, increasingly, NMR, provides the means to visualize the shape of a pro作者: 摘要 時間: 2025-3-31 17:43
Einführung in die qualitative Videoanalysements of variable (V.), diversity (D.), and junctional (J.) gene segments (.). Selection of these gene elements from their corresponding libraries of germ-line genes is governed by a site-specific, developmentally ordered process. In humans, the organization of the V. locus has been completely delin作者: Optometrist 時間: 2025-3-31 22:59
Soziale Ungleichheit und Armut,vice reader and to serve as a review of these concepts to the more advanced reader. Most of these concepts also apply to in vivo reactivity. Antigen-antibody reactions in vivo frequently involve subsequent reactions of the complexes with complement, but these reactions will be largely ignored for th作者: 說明 時間: 2025-4-1 03:58 作者: 音樂等 時間: 2025-4-1 09:20
https://doi.org/10.1007/978-3-658-10327-9ity immunoblotting (.) has proven to be a powerful and high-resolution method for estimating clonality of immune responses to a variety of antigens. This chapter describes the affinity immunoblotting method in detail.作者: 過多 時間: 2025-4-1 13:21 作者: 存在主義 時間: 2025-4-1 16:01
Anarchismus (Zusammenfassende Darstellung), thereafter, endogenous opioid peptides (endorphins) that also bound to these receptors were found in mammalian brain tissue. Subsequent pharmacological work revealed the existence of three main subclasses of receptors designated μ, δ, and κ. This work was confirmed by the recent cloning of these th作者: maintenance 時間: 2025-4-1 20:18
Formale Soziologie (Beziehungslehre), response to an antigen. The theoretical basis for the construction of idiotypic structures mimicking external antigen results from the fact that the conformation of some of the anti-idiotypic antibodies may be complementary to the three-dimensional structure of the binding site of the first antibod作者: 外露 時間: 2025-4-1 23:53 作者: 鐵塔等 時間: 2025-4-2 05:45
https://doi.org/10.1007/978-3-476-02844-0SA). The premise for generating antibody catalysts, as put forth by Jencks (.), was validated through early examples of specific hydrolytic catalysts for ester and carbonate substrates (., .). The initial success with TSA of acyl transfer processes as haptens led to derivation of antibodies as catal作者: CLASH 時間: 2025-4-2 10:27
