標題: Titlebook: Antibodies for Treating Cancer; Basics, Development, Melvyn Little Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusi [打印本頁] 作者: 決絕 時間: 2025-3-21 17:36
書目名稱Antibodies for Treating Cancer影響因子(影響力)
書目名稱Antibodies for Treating Cancer影響因子(影響力)學科排名
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書目名稱Antibodies for Treating Cancer網(wǎng)絡(luò)公開度學科排名
書目名稱Antibodies for Treating Cancer被引頻次
書目名稱Antibodies for Treating Cancer被引頻次學科排名
書目名稱Antibodies for Treating Cancer年度引用
書目名稱Antibodies for Treating Cancer年度引用學科排名
書目名稱Antibodies for Treating Cancer讀者反饋
書目名稱Antibodies for Treating Cancer讀者反饋學科排名
作者: Increment 時間: 2025-3-21 22:41
https://doi.org/10.1007/978-3-642-92196-4ip antibodies with a radioactive payload, they are conjugated with cage-like complexes (chelators) that bind the positively charged ions of radioactive metals. In more recent approaches to diminish side effects, the antibody-chelate conjugates have been loaded with radionuclides after binding their target molecules in the tumor tissue.作者: irradicable 時間: 2025-3-22 03:11 作者: 親密 時間: 2025-3-22 07:39 作者: 替代品 時間: 2025-3-22 11:56 作者: 離開真充足 時間: 2025-3-22 16:39
Book 2021 the reader step by step to the latest advances. Interesting anecdotes, together with self-explanatory and clearly structured figures with a humorous touch, facilitate the reader’s understanding of this complex topic. Clinical cases round out the book, making it a valuable aid for professionals in t作者: CLAM 時間: 2025-3-22 17:47
Antibodies and the Immune System,nts of the adaptive immune system comprising B and T lymphocytes. The major role played by cytokines in cellular signaling and regulatory mechanisms to prevent an overshooting immune reaction are also described.作者: Cubicle 時間: 2025-3-22 22:27 作者: 沙漠 時間: 2025-3-23 01:28 作者: 錢財 時間: 2025-3-23 07:33 作者: Fierce 時間: 2025-3-23 10:56
https://doi.org/10.1007/978-3-642-92196-4otect him from smallpox. Almost a century later, Louis Pasteur developed vaccinations against diseases such as anthrax and rabies using weakened pathogens. Shortly afterwards, Emil von Behring, Kitasato Shibasaburō, and Paul Ehrlich demonstrated that antitoxins in the serum of horses vaccinated with作者: Ambulatory 時間: 2025-3-23 14:35 作者: 桶去微染 時間: 2025-3-23 19:44 作者: perimenopause 時間: 2025-3-24 01:02
https://doi.org/10.1007/978-3-642-92196-4e regions at the end of the two arms of the Y-shaped antibody, and binding sites for components of the immune system are located in the constant regions of the basal Fc domain. There are five classes of constant regions (A, D, E, G, and M) which determine the particular function of an antibody. The 作者: 厚顏 時間: 2025-3-24 03:49 作者: 不可侵犯 時間: 2025-3-24 08:35
https://doi.org/10.1007/978-3-642-92196-4duce tumor cell death by the Fc-mediated effector functions of ADCC (antibody-dependent cellular cytotoxicity), ADCP (antibody-dependent cellular phagocytosis), and CDC (complement-dependent cytotoxicity) or by inhibiting the signaling pathway of growth hormone receptors on the tumor cell surface. T作者: GLARE 時間: 2025-3-24 12:03
https://doi.org/10.1007/978-3-642-92196-4 radionuclides. Most of the toxins from plants and bacteria are enzymes, a single molecule of which can catalyze thousands of reactions. In contrast, non-enzymatic reagents must be potent enough that only a few molecules are able to damage vital structures such as DNA and microtubules. Most of the c作者: START 時間: 2025-3-24 17:20 作者: Basilar-Artery 時間: 2025-3-24 20:28
Einführung in die moderne Kostenrechnung NK and T cells and to tumor-associated antigens (TAAs). Some are based on multivalent full-length antibodies, and others comprise only single chains of antibody variable domains. Indeed, the most successful bispecific antibody to date, a so-called BiTE for treating refractory or relapsed B-cell acu作者: Ventilator 時間: 2025-3-25 00:23 作者: Ferritin 時間: 2025-3-25 04:02
Die Kosten- und Leistungsstellenrechnung,nce of understanding the biology and mechanisms of cellular interactions within the tumor microenvironment (TME). A majority of antibodies in development for treating cancer are directed against immune checkpoints (ICs). They are being evaluated in more than 3000 clinical trials as first or second l作者: Accede 時間: 2025-3-25 10:56 作者: characteristic 時間: 2025-3-25 11:57
978-3-030-72601-0The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: FAWN 時間: 2025-3-25 19:53 作者: 翻布尋找 時間: 2025-3-26 00:01 作者: frenzy 時間: 2025-3-26 03:14
Book 2021by inhibition of negative immune regulation. Many of the antibodies that are now being brought to market target precisely these immune checkpoint modulators...The book addresses a broad readership, ranging from professionals and experts in the field to residents and medical students..作者: 隱藏 時間: 2025-3-26 06:57 作者: connoisseur 時間: 2025-3-26 10:10 作者: 史前 時間: 2025-3-26 16:09 作者: 草率女 時間: 2025-3-26 17:18
https://doi.org/10.1007/978-3-642-92196-4id tumors. They have opened a window for treating cancers such as malignant melanomas that were previously resistant to therapy. Tumors that are particularly amenable to treatment with IC inhibitors are characterized by a high mutation rate and a significant number of tumor-infiltrating lymphocytes 作者: 自然環(huán)境 時間: 2025-3-26 22:32
https://doi.org/10.1007/978-3-322-92045-4s of other antibodies to make bispecific or even multispecific recombinant antibodies. For example, dual binding antibodies can be used to recruit immune cells for inducing the lysis of tumor cells. To avoid the rapid excretion of these relatively small fragments from the circulation, they can be fu作者: insert 時間: 2025-3-27 01:23 作者: CHARM 時間: 2025-3-27 07:36 作者: chisel 時間: 2025-3-27 12:13 作者: 土坯 時間: 2025-3-27 17:30
Generation, Structure, and Function of Antibodies, Further diversity is created after an antigen binds to a B lymphocyte in the germinal centers. This stimulates B-cell proliferation and initiates a system for introducing a high number of mutations (somatic hypermutation) into the DNA region coding for the antigen-binding CDRs (complementarity-dete作者: OFF 時間: 2025-3-27 19:01
Of Mice and Men: Production of Therapeutic Antibodies,ntibodies. To screen these enormous libraries, the clonal selection system of the immune system was also imitated by coupling the antibody gene with its antibody product expressed on the surface of a microorganism, usually a bacteriophage. Those microorganisms were selected that bound with the highe作者: 翻布尋找 時間: 2025-3-27 22:30
Mediation of Tumor Cell Death by Naked Antibodies,id tumors. They have opened a window for treating cancers such as malignant melanomas that were previously resistant to therapy. Tumors that are particularly amenable to treatment with IC inhibitors are characterized by a high mutation rate and a significant number of tumor-infiltrating lymphocytes 作者: 解決 時間: 2025-3-28 02:26
Novel Modular Antibodies,s of other antibodies to make bispecific or even multispecific recombinant antibodies. For example, dual binding antibodies can be used to recruit immune cells for inducing the lysis of tumor cells. To avoid the rapid excretion of these relatively small fragments from the circulation, they can be fu作者: reserve 時間: 2025-3-28 09:08
Recruiting Killer Cells for Cancer Therapy,cells), namely, Kymriah and Yescarta targeting CD19, achieved a high number of complete responses in the treatment of refractory or relapsed B-ALL and diffuse large B-cell lymphoma (DLBCL). An increasing number of novel strategies are being developed to optimize CAR-T cell efficacy and overcome the 作者: 倫理學 時間: 2025-3-28 12:53
Cancer Incidence: Market for Therapeutic Antibodies,cted to overtake Humira as the top-selling biological drug. The median price of mAbs for 1 year of treatment in the United States in the area of oncology/hematology in 2019 was about $143,000. To facilitate decisions regarding reimbursement, some countries have established cost-effectiveness thresho作者: hieroglyphic 時間: 2025-3-28 16:45 作者: Urgency 時間: 2025-3-28 21:39
Life-Saving Antibodies: History of Immunization,otect him from smallpox. Almost a century later, Louis Pasteur developed vaccinations against diseases such as anthrax and rabies using weakened pathogens. Shortly afterwards, Emil von Behring, Kitasato Shibasaburō, and Paul Ehrlich demonstrated that antitoxins in the serum of horses vaccinated with作者: 落葉劑 時間: 2025-3-29 01:58 作者: 神圣在玷污 時間: 2025-3-29 05:53 作者: 職業(yè) 時間: 2025-3-29 10:04 作者: 施加 時間: 2025-3-29 13:45
Of Mice and Men: Production of Therapeutic Antibodies,ll from the spleen of an immunized mouse with a myeloma tumor cell. The result was an immortal hybridoma cell that produced abundant monoclonal antibodies. For therapeutic use, the immunogenicity of monoclonal antibodies has been reduced either by replacing the murine constant domains with human seq作者: Verify 時間: 2025-3-29 17:40
Mediation of Tumor Cell Death by Naked Antibodies,duce tumor cell death by the Fc-mediated effector functions of ADCC (antibody-dependent cellular cytotoxicity), ADCP (antibody-dependent cellular phagocytosis), and CDC (complement-dependent cytotoxicity) or by inhibiting the signaling pathway of growth hormone receptors on the tumor cell surface. T作者: BRUNT 時間: 2025-3-29 22:12
Antibodies as Magic Bullets, radionuclides. Most of the toxins from plants and bacteria are enzymes, a single molecule of which can catalyze thousands of reactions. In contrast, non-enzymatic reagents must be potent enough that only a few molecules are able to damage vital structures such as DNA and microtubules. Most of the c作者: 擦試不掉 時間: 2025-3-30 00:17
Novel Modular Antibodies, two β-pleated sheets stabilized by a disulfide bridge. The variable domains at the end of the Fab arms containing the hypervariable antigen-binding regions can be used for constructing “mini-antibodies” which retain the binding properties of the original antibody but without its effector functions.作者: indigenous 時間: 2025-3-30 05:48
