標(biāo)題: Titlebook: Antibiotics; Methods and Protocol Peter Sass Book 2017 Springer Science+Business Media New York 2017 antibacterial compounds.antibiotic bio [打印本頁] 作者: Weber-test 時間: 2025-3-21 17:41
書目名稱Antibiotics影響因子(影響力)
書目名稱Antibiotics影響因子(影響力)學(xué)科排名
書目名稱Antibiotics網(wǎng)絡(luò)公開度
書目名稱Antibiotics網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Antibiotics被引頻次
書目名稱Antibiotics被引頻次學(xué)科排名
書目名稱Antibiotics年度引用
書目名稱Antibiotics年度引用學(xué)科排名
書目名稱Antibiotics讀者反饋
書目名稱Antibiotics讀者反饋學(xué)科排名
作者: Occupation 時間: 2025-3-21 22:39
978-1-4939-8255-4Springer Science+Business Media New York 2017作者: 逢迎白雪 時間: 2025-3-22 04:23
Antibiotics978-1-4939-6634-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 范例 時間: 2025-3-22 07:40 作者: ERUPT 時間: 2025-3-22 10:22
https://doi.org/10.1007/978-3-642-40981-3s for nutritional resources in their nearby environment. For antimicrobial activity, nature has invented a great variety of mechanisms of antibiotic action that involve the perturbation of essential bacterial structures or biosynthesis pathways of macromolecules such as the bacterial cell wall, DNA,作者: Truculent 時間: 2025-3-22 15:05 作者: considerable 時間: 2025-3-22 18:02 作者: 犬儒主義者 時間: 2025-3-22 21:17 作者: 溫順 時間: 2025-3-23 02:48
Einführung in die Technische Mechanikgn (SBDD) and ligand-based drug design (LBDD) are the two general types of computer-aided drug design (CADD) approaches in existence. SBDD methods analyze macromolecular target 3-dimensional structural information, typically of proteins or RNA, to identify key sites and interactions that are importa作者: pantomime 時間: 2025-3-23 07:19 作者: 越自我 時間: 2025-3-23 09:45 作者: MILL 時間: 2025-3-23 13:57 作者: craven 時間: 2025-3-23 21:13
,Rotationssymmetrische Spannungszust?nde, of biosensor approaches is the avoidance of time-consuming and cost-intensive labeling procedures of the analytes. In this chapter, we give insight into a mass-sensitive surface-acoustic wave (SAW) biosensor, which represents an elegant and highly sensitive method to investigate binding events at a作者: 漂亮 時間: 2025-3-24 01:17 作者: 跳動 時間: 2025-3-24 06:17
https://doi.org/10.1007/978-3-540-37892-1plored as potential targets for inhibitory compounds. We give an overview of representative cell-based and enzymatic assays suitable for high-throughput-driven search for novel DNA metabolism inhibitors of established and novel DNA metabolism targets in bacteria. The protocol for a colorimetric coup作者: 變化無常 時間: 2025-3-24 07:52
https://doi.org/10.1007/978-3-540-37892-1 the endonuclease that catalyzes the 5′ end maturation of precursor tRNA and it is essential for cell survival. Bacterial RNase P has a distinct subunit composition compared to the eukaryal counterparts; therefore, it is an attractive antibacterial target. Here, we describe a real-time fluorescence-作者: 泰然自若 時間: 2025-3-24 11:14
Querkraftbiegung prismatischer Balken,acterial drugs and drug targets. Riboswitches represent attractive new antibacterial drug targets, because they not only inherently recognize a specific metabolite or ion with their RNA aptamer domain, but also often regulate essential metabolic pathways. Here, we describe a reporter gene-based scre作者: dithiolethione 時間: 2025-3-24 16:30 作者: nonplus 時間: 2025-3-24 20:27 作者: OTTER 時間: 2025-3-25 00:16 作者: 抱怨 時間: 2025-3-25 05:49
Expression Profiling of Antibiotic-Resistant Bacteria Obtained by Laboratory Evolutionbe the expression profiling of antibiotic-resistant . strains obtained by laboratory evolution, and a method for extracting a small number of genes whose expression changes can contribute to the acquisition of resistance.作者: 抱負(fù) 時間: 2025-3-25 09:24 作者: Blanch 時間: 2025-3-25 13:55
Methods in Molecular Biologyhttp://image.papertrans.cn/a/image/158423.jpg作者: objection 時間: 2025-3-25 16:06 作者: bronchiole 時間: 2025-3-25 20:01
Einführung in die Technische Mechanikgene content or regulation..Apart from the mere identification of gene clusters, several other factors such as determining cluster boundaries and assessing the novelty of the detected cluster are important. For this purpose, comparison of the predicted secondary metabolite genes with different clust作者: 來自于 時間: 2025-3-26 00:08 作者: 咆哮 時間: 2025-3-26 06:24 作者: MILK 時間: 2025-3-26 09:09 作者: 使成整體 時間: 2025-3-26 15:01
Inelastisches Materialverhalten,s pharmacologically tractable with specific antibiotics. The assay described in this chapter is tailored to the identification of molecules affecting the first stage of translation initiation, which is the most dissimilar step in bacteria vs. mammals. The effect of the compounds under analysis is as作者: hypotension 時間: 2025-3-26 17:00 作者: 攀登 時間: 2025-3-26 21:31
Mining Bacterial Genomes for Secondary Metabolite Gene Clustersgene content or regulation..Apart from the mere identification of gene clusters, several other factors such as determining cluster boundaries and assessing the novelty of the detected cluster are important. For this purpose, comparison of the predicted secondary metabolite genes with different clust作者: 籠子 時間: 2025-3-27 04:07 作者: Lumbar-Stenosis 時間: 2025-3-27 07:48
Application of a , Whole-Cell Biosensor (,) for the Identification of Cell Wall Active Antibacteriallawn of the reporter strain, allows for quantitative and time-resolved detection of antimicrobial compounds. Due to the very low technical demands of this procedure, we expect it to be easily applicable to a large variety of candidate producer strains and growth conditions.作者: ADJ 時間: 2025-3-27 10:01
Mass-Sensitive Biosensor Systems to Determine the Membrane Interaction of Analytes investigations, including antibiotic research. The interaction with the bacterial membrane or certain target structures therein is the essential mode of action for various antibacterial compounds. Beside targeted interaction, an unspecific membrane binding or membrane insertion of drugs can contrib作者: Encephalitis 時間: 2025-3-27 15:56 作者: 太空 時間: 2025-3-27 18:26
1064-3745 nd cutting-edge, .Antibiotics: Methods and Protocols. aims to inspire scientific work in the exciting field of antibiotic research..978-1-4939-8255-4978-1-4939-6634-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: CODE 時間: 2025-3-28 00:54
,Rotationssymmetrische Spannungszust?nde,totoxic and hemolytic effects, e.g., lactate dehydrogenase release, cell proliferation analysis, cell viability analysis, and hemolysis assay of antimicrobial compounds on human cells, are described in this chapter.作者: Consensus 時間: 2025-3-28 03:35
Cytotoxicity Assays as Predictors of the Safety and Efficacy of Antimicrobial Agentstotoxic and hemolytic effects, e.g., lactate dehydrogenase release, cell proliferation analysis, cell viability analysis, and hemolysis assay of antimicrobial compounds on human cells, are described in this chapter.作者: Lymphocyte 時間: 2025-3-28 10:10 作者: 漂亮才會豪華 時間: 2025-3-28 12:14
1064-3745 ation advice from the experts.Includes supplementary materia.This volume provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, and methods for the analysis and detection of microbial adaptation strategies. ?.Antibiot作者: 胖人手藝好 時間: 2025-3-28 17:17
Einführung in die Technische Mechaniktly a microorganism. In this chapter, a general workflow, which can easily be adapted to the lab, is described. Both fermentation on solid and in liquid medium is explained, and examples of hand on procedures are given.作者: cliche 時間: 2025-3-28 20:11 作者: Receive 時間: 2025-3-29 01:31 作者: Respond 時間: 2025-3-29 05:50 作者: 填滿 時間: 2025-3-29 11:02
https://doi.org/10.1007/978-3-540-37892-1ut-driven search for novel DNA metabolism inhibitors of established and novel DNA metabolism targets in bacteria. The protocol for a colorimetric coupled primase-inorganic pyrophosphatase assay developed by our group is described in detail.作者: 領(lǐng)巾 時間: 2025-3-29 12:25 作者: 大溝 時間: 2025-3-29 19:03
Structure Elucidation of Antibiotics by NMR Spectroscopynal (1D) and two-dimensional (2D) NMR methods are available today and the list continues to expand. In this chapter, we will consider the key NMR experiments that provide useful information for compound structure elucidation.作者: RALES 時間: 2025-3-29 22:08
Determination of Bacterial Membrane Impairment by Antimicrobial Agents leakage of low molecular weight compounds such as ions, amino acids and ATP, and subsequent membrane depolarization. This article describes two techniques to assess antibiotic-induced membrane impairment in vivo.作者: Physiatrist 時間: 2025-3-30 01:26
Measurement of Cell Membrane Fluidity by Laurdan GP: Fluorescence Spectroscopy and Microscopy the mechanism of action of membrane targeting antimicrobials, but the corresponding analyses have been hampered by the absence of readily available analytical tools. Here, we provide detailed protocols that allow straightforward measurement of antibiotic compound-triggered changes in membrane fluidity both in vivo and in vitro.作者: upstart 時間: 2025-3-30 07:40 作者: 舔食 時間: 2025-3-30 09:49
Book 2017atory protocols, and tips on troubleshooting and avoiding known pitfalls...Authoritative and cutting-edge, .Antibiotics: Methods and Protocols. aims to inspire scientific work in the exciting field of antibiotic research..作者: 平靜生活 時間: 2025-3-30 14:04 作者: 全神貫注于 時間: 2025-3-30 17:18
Einführung in die Technische Mechanikan . host. This guide also presents in vitro phosphorylation assays to screen for new antimicrobial compounds that target bacterial histidine kinases using radioactively labeled ATP and, as a novel approach, Phos-tag acrylamide gel electrophoresis to detect phosphorylated proteins by mobility shift in the polyacrylamide gel.作者: pineal-gland 時間: 2025-3-30 20:42 作者: 強(qiáng)制令 時間: 2025-3-31 02:11
Bacterial Histidine Kinases: Overexpression, Purification, and Inhibitor Screenan . host. This guide also presents in vitro phosphorylation assays to screen for new antimicrobial compounds that target bacterial histidine kinases using radioactively labeled ATP and, as a novel approach, Phos-tag acrylamide gel electrophoresis to detect phosphorylated proteins by mobility shift in the polyacrylamide gel.作者: 啜泣 時間: 2025-3-31 06:14
Querkraftbiegung prismatischer Balken,en to identify compounds that activate the thiamine pyrophosphate (TPP) riboswitch in bacteria. This assay can be easily adapted for different riboswitch classes and thus has the potential to target many essential metabolic pathways and a broad spectrum of bacterial pathogens.作者: grovel 時間: 2025-3-31 10:10
Book 2017 and methods for the analysis and detection of microbial adaptation strategies. ?.Antibiotics: Methods and Protocols. guides readers through chapters on production and design, mode of action, and response and susceptibility. Written in the highly successful .Methods in Molecular Biology .series form
