標題: Titlebook: Antiangiogenic Agents in Cancer Therapy; Beverly A. Teicher,Lee M. Ellis Book 2008Latest edition Humana Press 2008 CNS.Chemokine.angiogene [打印本頁] 作者: CHORD 時間: 2025-3-21 18:43
書目名稱Antiangiogenic Agents in Cancer Therapy影響因子(影響力)
書目名稱Antiangiogenic Agents in Cancer Therapy影響因子(影響力)學科排名
書目名稱Antiangiogenic Agents in Cancer Therapy網絡公開度
書目名稱Antiangiogenic Agents in Cancer Therapy網絡公開度學科排名
書目名稱Antiangiogenic Agents in Cancer Therapy被引頻次
書目名稱Antiangiogenic Agents in Cancer Therapy被引頻次學科排名
書目名稱Antiangiogenic Agents in Cancer Therapy年度引用
書目名稱Antiangiogenic Agents in Cancer Therapy年度引用學科排名
書目名稱Antiangiogenic Agents in Cancer Therapy讀者反饋
書目名稱Antiangiogenic Agents in Cancer Therapy讀者反饋學科排名
作者: ineptitude 時間: 2025-3-21 23:30 作者: 熱心 時間: 2025-3-22 00:35
Beverly A. Teicher,Lee M. EllisCurrent perspectives on state-of-the-art therapies.Contains chapters specific to angiogenesis and antiangiogenic treatment of many malignant diseases作者: 褲子 時間: 2025-3-22 06:58
Cancer Drug Discovery and Developmenthttp://image.papertrans.cn/a/image/158384.jpg作者: OPINE 時間: 2025-3-22 10:10
Einführung in die Physikalische Chemie vascular growth during physiological and pathological processes in the adult. The VEGF family of ligands in mammals includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, and placenta growth factor (PlGF). These ligands bind to and activate three receptor tyrosine kinases, designated VEGFR-1, VEGFR-2, and VEGFR-作者: CHASM 時間: 2025-3-22 14:50 作者: 放牧 時間: 2025-3-22 20:23 作者: 獨白 時間: 2025-3-22 23:50
Der dritte Hauptsatz der Thermodynamik,have been investigated in attempts at understanding the mechanisms that regulate how blood vessels develop in health and disease. In the tumor microenvironment, factors such as hypoxia and acidosis impinge on normal endothelial cell (EC) function. Accordingly, the vascular structure in tumors is hig作者: Ondines-curse 時間: 2025-3-23 04:33 作者: Fibrillation 時間: 2025-3-23 08:00
Heinrich Labhart,Hans Dieter Breuert was considered that only nearby host vasculature provided the necessary cellular components that comprise blood vessels, endothelial cells (EC), and pericytes. Data gathered in recent years have supported the notion that endothelial precursor cells (EPC) exist postnatal and that EPC can also contr作者: dagger 時間: 2025-3-23 12:09
Heinrich Labhart,Hans Dieter Breuerdothelial cells, stabilize the newly formed endothelial tubes, modulate blood flow and vascular permeability, and regulate endothelial proliferation, differentiation, migration and survival. This chapter will review the biology, physiology and pathology of pericytes, as well as their role in angioge作者: ectropion 時間: 2025-3-23 15:33
Heinrich Labhart,Hans Dieter Breuer, investigators have isolated endothelial cells from fresh human tumor specimens and subjected them to RNA-based gene-expression analysis. The data indicate that there are few proteins that distinguish tumor vasculature from normal vasculature and re-enforce the notion that the endothelium is a tiss作者: TAIN 時間: 2025-3-23 21:27 作者: charisma 時間: 2025-3-24 00:14
https://doi.org/10.1007/978-3-642-73942-2bryonic lethality with defects in embryonic vasculature. Multiple ligands for Tie2, named angiopoietin (Ang), have been identified. Ang1, an agonist, stimulates Tie2 phosphorylation in endothelial cells (EC). Ang2 has been considered to be an antagonist of Tie2 that blocks Tie2 activation induced by作者: 詞匯表 時間: 2025-3-24 02:32 作者: 埋葬 時間: 2025-3-24 06:53 作者: 外表讀作 時間: 2025-3-24 14:17 作者: obsession 時間: 2025-3-24 18:31
Einführung in die Physiologie des Menschennance of quiescent vasculature. Recent observations from clinical trials using anti-VEGF therapy, as well as from the disease preeclampsia, point to a role for VEGF in the adult. This chapter explores both clinical and experimental VEGF neutralization studies and discusses the potential role of VEGF作者: Paradox 時間: 2025-3-24 19:38 作者: lactic 時間: 2025-3-25 00:42 作者: assail 時間: 2025-3-25 04:25
Robert F. Schmidt,Gerhard Thewsvessels is required. This recognition has led to the development and clinical advancement of novel antiangiogenic therapeutics in cancer management. An alternative approach to targeting the neovasculature associated with tumors is not to interfere with new vessel formation but rather to disrupt the 作者: 影響 時間: 2025-3-25 08:22
Vascular Endothelial Growth Factor Family and Its Receptors vascular growth during physiological and pathological processes in the adult. The VEGF family of ligands in mammals includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, and placenta growth factor (PlGF). These ligands bind to and activate three receptor tyrosine kinases, designated VEGFR-1, VEGFR-2, and VEGFR-作者: GREG 時間: 2025-3-25 13:40
The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumorslated angiogenesis, instability in perfusion, and hypoxia. Interactions between tumor and endothelial cells occur during tumor growth and in response to therapy. These interactions are of central importance in establishing codependence that contributes to promotion of tumor and endothelial cell surv作者: conscience 時間: 2025-3-25 18:19 作者: ciliary-body 時間: 2025-3-25 23:55 作者: HAWK 時間: 2025-3-26 03:49 作者: 共棲 時間: 2025-3-26 05:05 作者: Compassionate 時間: 2025-3-26 09:50 作者: 教義 時間: 2025-3-26 14:27 作者: defibrillator 時間: 2025-3-26 18:18
Chemokines in Angiogenesisogenesis can occur under physiological conditions that include embryogenesis and the ovarian/menstrual cycle. In contrast, pathological angiogenesis is associated with chronic inflammation/chronic fibroproliferative disorders and tumorigenesis of cancer. Net angiogenesis is determined by a balance i作者: EVADE 時間: 2025-3-27 00:38
Angiopoietin/Tie2 Signaling Regulates Tumor Angiogenesisbryonic lethality with defects in embryonic vasculature. Multiple ligands for Tie2, named angiopoietin (Ang), have been identified. Ang1, an agonist, stimulates Tie2 phosphorylation in endothelial cells (EC). Ang2 has been considered to be an antagonist of Tie2 that blocks Tie2 activation induced by作者: escalate 時間: 2025-3-27 03:18 作者: 等級的上升 時間: 2025-3-27 05:16
Tumor Blood Vessels been possible to replicate many of these vessel types by introducing an adenovirus expressing VEGF-A. (Ad-VEGF-A.) into mouse tissues. At least five different microvessels form in sequence from preexisting venules, each with distinctly different structural and functional properties. Mother vessels 作者: Feckless 時間: 2025-3-27 09:27
Lymphatic System in the Pathology of Cancer permeability during inflammation or to repeatedly grow and regress during the female reproductive cycle are but two examples of such dynamism. One consequence that stems from above considerations is that the microcirculation cannot be both flexible and completely impermeable to plasma. Thus, certai作者: 散步 時間: 2025-3-27 15:38 作者: 付出 時間: 2025-3-27 20:51 作者: 花束 時間: 2025-3-28 01:36
Metronomic Low-Dose Antiangiogenic Chemotherapy in Mice and Manal chemotherapy drugs at relatively low doses over long periods in the absence of prolonged drug-free periods. Anti-tumor efficacy, which in some cases can be remarkably effective in various experimental mouse models of cancer, even in the absence of toxicity, is thought to be mediated mainly by ant作者: ARY 時間: 2025-3-28 03:00 作者: 一再困擾 時間: 2025-3-28 07:03
The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumorsival, treatment resistance, enhanced invasion, and metastasis. Results indicate that concurrent targeting of both tumor and endothelial cells may be of central importance in improving treatment responses to both radiation and chemotherapy.作者: Truculent 時間: 2025-3-28 10:59
Role of Pericytes in Angiogenesisnesis. We will also discuss the potential relevance of pericytes in anti-angiogenic therapeutic approaches. Dual targeting of both endothelial and pericytes may provide more efficacious anti-angiogenic approaches for cancer therapy.作者: 飛行員 時間: 2025-3-28 17:32 作者: Guaff豪情痛飲 時間: 2025-3-28 21:32
VEGF in the Adult in the adult in maintaining endothelial cell (EC) survival and fenestration, as well as its action on non-ECs. Properties that may affect VEGF action . are discussed. Finally, implications for use in anti- and pro-angiogenic therapy are proposed.作者: 情感 時間: 2025-3-29 02:03
,Die Erscheinungen an den Grenzfl?chen,ns, respectively, to supply and drain the tumor microvasculature. This classification has helped to elucidate the steps and mechanisms by which tumors induce new blood vessels and hopefully will lead to the identification of new therapeutic targets that can improve anti-angiogenic tumor therapy.作者: Arroyo 時間: 2025-3-29 04:56 作者: 疲憊的老馬 時間: 2025-3-29 08:07 作者: 圍巾 時間: 2025-3-29 13:00 作者: Type-1-Diabetes 時間: 2025-3-29 17:45 作者: Neolithic 時間: 2025-3-29 22:18
The Role of Integrins in Tumor Angiogenesis Currently, humanized or chimeric antibody antagonists of integrins α5β1, αvβ3 and αvβ5 and peptide inhibitors of these integrins are in clinical trials as angiogenesis-inhibiting agents for cancer therapy.作者: 易于交談 時間: 2025-3-30 01:11 作者: instate 時間: 2025-3-30 05:10
Chemokines in Angiogenesisin the regulation of angiogenesis. Based on their structure, CXC chemokines can be divided into two groups that either promote or inhibit angiogenesis, and they are therefore uniquely placed to regulate net angiogenesis in both physiological and pathological conditions including cancer growth.作者: 高歌 時間: 2025-3-30 10:59
Einführung in die Physikalische Chemieival, treatment resistance, enhanced invasion, and metastasis. Results indicate that concurrent targeting of both tumor and endothelial cells may be of central importance in improving treatment responses to both radiation and chemotherapy.作者: 蜿蜒而流 時間: 2025-3-30 13:25 作者: 含水層 時間: 2025-3-30 20:16 作者: AXIS 時間: 2025-3-30 22:11
Einführung in die Physiologie des Menschen in the adult in maintaining endothelial cell (EC) survival and fenestration, as well as its action on non-ECs. Properties that may affect VEGF action . are discussed. Finally, implications for use in anti- and pro-angiogenic therapy are proposed.作者: finale 時間: 2025-3-31 02:00 作者: 對手 時間: 2025-3-31 08:33 作者: Instrumental 時間: 2025-3-31 12:01 作者: Obstacle 時間: 2025-3-31 16:06
The Extracellular Matrix and VEGF Processingion on the question of how VEGF becomes released from the extracellular environment and contributes to tumor neovascularization. We discuss this point in the larger context of matrix interaction with growth factors and their modulation by matrix metalloproteinases (MMPs).作者: 四溢 時間: 2025-3-31 18:47 作者: 仲裁者 時間: 2025-3-31 23:59
Newer Vascular Targets-3 is an intracellular phosphatase that is expressed not only in tumor vasculature but in aggressive disease. SAGE analysis of subpopulations of tumors has provided useful leads for new vascular targets. It remains to the basic scientists to elucidate the function of these proteins and to the “drug 作者: 或者發(fā)神韻 時間: 2025-4-1 01:54
Angiopoietin/Tie2 Signaling Regulates Tumor Angiogenesisangiogenesis. The interaction of the Ang/Tie2 pathway with the VEGF pathway has also been demonstrated. Elevated VEGF and Ang2 expressions are associated with increased tumor angiogenesis. Ang2 corresponds positively with tumor development and progression as well as with metastasis and correlates ne
