作者: 冬眠 時(shí)間: 2025-3-21 23:34 作者: MUTED 時(shí)間: 2025-3-22 02:49 作者: MULTI 時(shí)間: 2025-3-22 06:15
0171-2004 ated account of the knowledge and findings accumulated since the complexity of angiotensin was so accurately recognized..978-3-642-62132-1978-3-642-18495-6Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: Enthralling 時(shí)間: 2025-3-22 11:20 作者: agitate 時(shí)間: 2025-3-22 13:30 作者: 嚴(yán)峻考驗(yàn) 時(shí)間: 2025-3-22 18:44
General Physiology and Pathophysiology of the Renin-Angiotensin Systemprimarily be viewed as a powerful regulatory system for the conservation of salt and blood volume, and the preservation of an adequate blood pressure (BP). To circumvent the major threats of low blood volume and low BP, animals and our ancestors, with a diet relatively poor in sodium, needed powerfu作者: 六邊形 時(shí)間: 2025-3-23 00:15
Angiotensin as a Cytokine Implicated in Accelerated Cellular TurnoverThe increased proliferative phenotype found as early as birth in hypertensives is accompanied by age-dependent alterations in apoptosis, contributing to neonatal hyperplasia of the heart, aorta, and kidneys. During the course of life, accelerated cell turnover occurs and is modifiable by antihyperte作者: corpus-callosum 時(shí)間: 2025-3-23 03:12 作者: 怪物 時(shí)間: 2025-3-23 06:41 作者: 遣返回國(guó) 時(shí)間: 2025-3-23 12:17
Renin-Angiotensin System: Plasma Versus Tissuess via circulating blood, has been challenged in the past two decades by studies demonstrating high tissue levels of angiotensin II, as well as release of angiotensin I from tissue sites. The high tissue levels of angiotensin II could not be explained on the basis of diffusion and/or receptor-mediate作者: 遭受 時(shí)間: 2025-3-23 17:04 作者: Integrate 時(shí)間: 2025-3-23 18:02 作者: fiscal 時(shí)間: 2025-3-24 00:09
Knockout Models of the Renin-Angiotensin System different classes of G protein-coupled receptors, termed angiotensin II AT. receptors and AT. receptors. Transgenic mouse models have greatly advanced our understanding of the specific functions of the individual parts of the renin angiotensin aldosterone system (RAAS). Recently, all components of 作者: micronutrients 時(shí)間: 2025-3-24 03:43
Transgenics of the RAS genes in rodents. It allows overexpression and—by the use of antisense constructs—also attenuation of gene expression in rats and mice. Transgenic technology has been extensively used to study the functions of the renin-angiotensin system (RAS). Most transgenic rat or mouse models overexpressing re作者: 為現(xiàn)場(chǎng) 時(shí)間: 2025-3-24 09:31
Gene Therapy and the Renin-Angiotensin Systemstem offers targets that are know to be effective based on pharmaceutical drugs that have targeted angiotensin-converting enzyme (ACE) angiotensin type I receptors (AT.R). Other targets include renin and angiotensinogen. It is clear that lowering overactive amounts of angiotensin II has positive eff作者: 離開(kāi)就切除 時(shí)間: 2025-3-24 11:05
General Physiology and Pathophysiology of the Renin-Angiotensin Systemal pressure and fluid volumes required to achieve sodium balance (prevention of salt-sensitivity), and to increase the efficiency of cardiovascular dynamics by promoting the growth of the heart and vessels, and sensitizing blood vessels to vasoconstrictor agents (slowest actions of angiotensin). Act作者: INERT 時(shí)間: 2025-3-24 16:38 作者: MITE 時(shí)間: 2025-3-24 19:44
Immunohistochemistry of Angiotensin median eminence and the neurohypophysis. Recent studies have shown that in spite of using the same antigen molecule for immunization as well as for affinity purification, different staining pattern are obtained, suggesting that the different carrier proteins forced the production of different antib作者: 特別容易碎 時(shí)間: 2025-3-25 00:01
Renin-Angiotensin System: Plasma Versus Tissuesro)renin receptors located on the cell membrane, combined with the fact that angiotensin-converting enzyme (ACE) also is a membrane-associated enzyme, favours angiotensin generation on the cell surface. Although renin has also been demonstrated intracellularly, intracellular angiotensin generation i作者: 技術(shù) 時(shí)間: 2025-3-25 04:01
Angiotensin-Endothelin Interactionsompletely prevent it. Interestingly, ET also appears to mediate part of Ang II-induced vascular superoxide production in vivo. Thus, blocking ET receptors may provide similar cardiovascular benefits as inhibiting the renin-angiotensin-aldosterone system, and the combination of inhibitors of both sys作者: 哪有黃油 時(shí)間: 2025-3-25 08:50 作者: 補(bǔ)充 時(shí)間: 2025-3-25 13:47
Knockout Models of the Renin-Angiotensin Systemting effects of AT. receptors in vascular smooth muscle cells and in cardiac myocytes. Targeted deletions of angiotensinogen and ACE genes have extended our knowledge of the embryonic functions of the renin angiotensin system. Most recently, a novel angiotensin-converting-enzyme (ACE2) has been clon作者: Isolate 時(shí)間: 2025-3-25 17:53
Transgenics of the RAScreased blood pressure, supporting an important role of the central renin-angiotensin system in cardiovascular control. Enhanced angiotensin II generation exclusively in the kidney of transgenic mice also led to hypertension. Transgenic animals with cardiac overexpression of RAS components were pron作者: Gene408 時(shí)間: 2025-3-25 23:18
Gene Therapy and the Renin-Angiotensin Systemre. Gene therapy with antisense offers long-lasting, highly specific inhibition of gene products such as the components of RAS when their overactivity needs to be reduced in order to ameliorate disease.作者: Paradox 時(shí)間: 2025-3-26 00:22
EU Integrated Urban Initiativesal pressure and fluid volumes required to achieve sodium balance (prevention of salt-sensitivity), and to increase the efficiency of cardiovascular dynamics by promoting the growth of the heart and vessels, and sensitizing blood vessels to vasoconstrictor agents (slowest actions of angiotensin). Act作者: Hippocampus 時(shí)間: 2025-3-26 05:11
https://doi.org/10.1007/978-3-319-64078-5 activity of angiotensin II-regulated Na. transporters and augmented production of endogenous ouabain-like substances have been detected in experimental models of primary hypertension. Recent data show that both ouabain and intracellular Na. are involved in the regulation of gene expression and apop作者: 松馳 時(shí)間: 2025-3-26 08:32
https://doi.org/10.1007/978-3-319-64955-9 median eminence and the neurohypophysis. Recent studies have shown that in spite of using the same antigen molecule for immunization as well as for affinity purification, different staining pattern are obtained, suggesting that the different carrier proteins forced the production of different antib作者: Dysarthria 時(shí)間: 2025-3-26 14:59 作者: ventilate 時(shí)間: 2025-3-26 19:41 作者: 巨頭 時(shí)間: 2025-3-26 22:19 作者: 朝圣者 時(shí)間: 2025-3-27 05:08 作者: deriver 時(shí)間: 2025-3-27 08:05
EU Internet Law in the Digital Eracreased blood pressure, supporting an important role of the central renin-angiotensin system in cardiovascular control. Enhanced angiotensin II generation exclusively in the kidney of transgenic mice also led to hypertension. Transgenic animals with cardiac overexpression of RAS components were pron作者: 除草劑 時(shí)間: 2025-3-27 10:16
Evangelia Vagena,Petros Ntellisre. Gene therapy with antisense offers long-lasting, highly specific inhibition of gene products such as the components of RAS when their overactivity needs to be reduced in order to ameliorate disease.作者: 倔強(qiáng)一點(diǎn) 時(shí)間: 2025-3-27 15:12 作者: Ondines-curse 時(shí)間: 2025-3-27 18:20
https://doi.org/10.1007/978-3-642-18495-6Aldosterone; Angiotensin; Angiotensin AT1 Receptor Antagonists; Angiotensin II; Inhibitors of the Renin-作者: 大炮 時(shí)間: 2025-3-28 00:27 作者: Corroborate 時(shí)間: 2025-3-28 05:40
Angiotensin Vol. I978-3-642-18495-6Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: 形上升才刺激 時(shí)間: 2025-3-28 09:20 作者: 危險(xiǎn) 時(shí)間: 2025-3-28 13:31
https://doi.org/10.1007/978-3-319-64078-5The increased proliferative phenotype found as early as birth in hypertensives is accompanied by age-dependent alterations in apoptosis, contributing to neonatal hyperplasia of the heart, aorta, and kidneys. During the course of life, accelerated cell turnover occurs and is modifiable by antihyperte作者: Herpetologist 時(shí)間: 2025-3-28 15:15
https://doi.org/10.1007/978-3-319-64078-5ediated by stimulation of the angiotensin II receptor 1 (AT1R), whereas the angiotensin receptor 2 (AT2R) inhibits angiogenesis. The pro-angiogenic activity of angiotensin II is believed to be predominantly mediated by stimulation of VEGF expression. Moreover, a transactivation of the growth promoti作者: A簡(jiǎn)潔的 時(shí)間: 2025-3-28 20:29 作者: Optic-Disk 時(shí)間: 2025-3-28 23:05 作者: 彎曲道理 時(shí)間: 2025-3-29 05:12
Developing a Right to be Forgottenricting factor. It is therefore not surprising that some of the physiological or pathological effects of angiotensin II are in fact mediated by endothelin through interaction with its specific receptors. For instance, ET receptor antagonists block part of the pressor effect of Ang II, especially whe作者: osteopath 時(shí)間: 2025-3-29 08:22
Developing a Right to be Forgottend and tested in linkage and association studies in regard to cardiovascular traits such as essential hypertension, coronary disease, and diabetic nephropathy. Gene structure, polymorphisms, and associations are summarised for each gene. Association between polymorphisms of the angiotensinogen and an作者: Incommensurate 時(shí)間: 2025-3-29 12:23
EU Internet Law in the Digital Era different classes of G protein-coupled receptors, termed angiotensin II AT. receptors and AT. receptors. Transgenic mouse models have greatly advanced our understanding of the specific functions of the individual parts of the renin angiotensin aldosterone system (RAAS). Recently, all components of 作者: GAVEL 時(shí)間: 2025-3-29 18:15 作者: instate 時(shí)間: 2025-3-29 21:52 作者: HARP 時(shí)間: 2025-3-30 03:46
Thomas Unger,Bernward A. Sch?lkensIncludes supplementary material: 作者: 在駕駛 時(shí)間: 2025-3-30 04:33
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/a/image/157437.jpg