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標(biāo)題: Titlebook: Androgens and Androgen Receptor; Mechanisms, Function Chawnshang Chang Book 2002 Kluwer Academic Publishers 2002 DNA.autoimmune disease.can [打印本頁]

作者: ISSUE    時(shí)間: 2025-3-21 19:30
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作者: 的事物    時(shí)間: 2025-3-21 21:22

作者: cortex    時(shí)間: 2025-3-22 00:41
https://doi.org/10.1007/978-1-4842-1811-2Simply stated, androgens are essential for normal penile development. However, the exact molecular mechanisms by which androgens affect the formation of the penis remain largely unknown. In this chapter, we will review the embryology of the penis and our current, but limited, understanding of the role of androgens in the development of the penis.
作者: 羅盤    時(shí)間: 2025-3-22 05:06
https://doi.org/10.1007/978-3-658-09402-7Osteoporosis is a major health problem, not only in women but also in men. The skeletal effects of estrogen deficiency and replacement therapy are well established in women. More recently, it has also been recognized that androgen deficiency induces bone loss and osteoporosis in men and that this process can be reversed by androgen replacement.
作者: GRIEF    時(shí)間: 2025-3-22 11:09
The Expanded Poly-Q Length Within AR and AR Coregulator AIB1 and Their Clinical Implications,The cloning of the androgen receptor gene in 1988 . and identification of androgen receptor (AR) coactivators have greatly improved our understanding of intracellular androgenic action and the role of androgenicity in many androgen-dependent disorders.
作者: terazosin    時(shí)間: 2025-3-22 14:48

作者: WITH    時(shí)間: 2025-3-22 19:44

作者: Electrolysis    時(shí)間: 2025-3-22 23:47
https://doi.org/10.1007/978-1-4615-1161-8DNA; autoimmune disease; cancer; dermatology; endocrinology; erectile dysfunction; fertility; oncology; ovar
作者: languor    時(shí)間: 2025-3-23 03:34

作者: 靦腆    時(shí)間: 2025-3-23 07:46
Natural Products and Environmental Androgens/Antiandrogens,ll be diagnosed (American Cancer Society). Although the exact etiology of this disease needs to be further elucidated, environmental factors such as diet and their complex interactions with androgens are known to play critical roles in the development, treatment, and most importantly, prevention of prostate cancer.
作者: SAGE    時(shí)間: 2025-3-23 11:07
http://image.papertrans.cn/a/image/157050.jpg
作者: Defense    時(shí)間: 2025-3-23 16:31

作者: 過份    時(shí)間: 2025-3-23 19:02

作者: jocular    時(shí)間: 2025-3-24 00:39
Harald Ehrentraut,Agnieszka Chrzanowskaroids testosterone (T) and dihydrotestosterone (DHT). In addition to androgens, paracrine and autocrine regulation of cell growth by peptide growth factors and cytokines contribute to prostate homeostasis. Unlike steroid hormones, growth factors regulate cellular responses through binding to membran
作者: 十字架    時(shí)間: 2025-3-24 02:41

作者: AWL    時(shí)間: 2025-3-24 09:40

作者: 脊椎動(dòng)物    時(shí)間: 2025-3-24 12:07

作者: BALE    時(shí)間: 2025-3-24 14:55
Vibration Analysis of n-dof Systems,ll be diagnosed (American Cancer Society). Although the exact etiology of this disease needs to be further elucidated, environmental factors such as diet and their complex interactions with androgens are known to play critical roles in the development, treatment, and most importantly, prevention of
作者: 破譯    時(shí)間: 2025-3-24 20:16
Yury A. Rossikhin,Marina V. Shitikovan male reproduction, the prostate functions as a sex accessory gland that contributes 30-40% of the fluid present in the seminal plasma of the ejaculate. However, in aging men the prostate is of clinical significance as the site for two common diseases, benign prostatic hyperplasia (BPH) and prostat
作者: Crohns-disease    時(shí)間: 2025-3-25 01:27
Routing in Telephone and Data Networks,epeat in the first exon of the androgen receptor (AR) gene (Kennedy .., 1968; La Spada et al., 1991). In SBMA patients, a normally polymorphic CAG repeat (10–36 CAGs) expands to 38–66 CAGs. The number of CAG repeats is inversely correlated with the age of onset of the disease .. SBMA is the first ne
作者: 一個(gè)攪動(dòng)不安    時(shí)間: 2025-3-25 07:07
https://doi.org/10.1007/978-1-4615-0251-7x. In male pseudohermaphroditism, the genital differentiation of each individual is different as compared to normal males with 46,XY chromosome and the presence of testes. Male pseudohermaphroditism is generally classified into 2 categories, 1) defects in testicular activity including testicular reg
作者: 北極熊    時(shí)間: 2025-3-25 10:28
Implementation of the Simulation Models,oids in the modulation of immune responsiveness and autoimmunity. Most human autoimmune diseases exhibit a sexually dimorphic incidence, with females affected more frequently than males (.). Clinical observations of the impact of gonadal steroids on these autoimmune processes are largely anecdotal,
作者: CRAMP    時(shí)間: 2025-3-25 11:53
Protecting Against SQL Injection,.; .; .; .; .; .). As a classical steroid hormone receptor, AR requires the binding of a ligand for activation of its function as a transcriptional modulator. The classical ligands known to activate AR include testosterone (T) and its metabolites, such as 5α-dihydrotestosterone (DHT). Once a ligand
作者: Individual    時(shí)間: 2025-3-25 18:28

作者: angiography    時(shí)間: 2025-3-25 23:29
Sheng Xiao,Weibo Gong,Don Towsleys. Androgens or the lack of estrogens have often been regarded as the proximate cause underlying this male disadvantage. With the prospects of much wider therapeutic applications of androgens (contraception, treatment of patients with aplastic anaemia or sarcopenic, osteopenic and dysphoric states,
作者: 易改變    時(shí)間: 2025-3-26 00:52

作者: BALE    時(shí)間: 2025-3-26 05:40
https://doi.org/10.1007/978-3-319-56502-6gh their binding to the androgen receptor (AR) which is a nuclear receptor superfamily member. These androgen-AR complexes then enhance their target genes’ expression by binding to response elements in the promoter region of those target genes (.). Some androgen actions require intracellular convers
作者: 愛花花兒憤怒    時(shí)間: 2025-3-26 11:28
basic scientists, and clinicians as both a study guide and reference of research in the androgen field. It could also be used as an advanced level text in endocrinology, urology, OBGYN, or oncology.978-1-4613-5422-2978-1-4615-1161-8
作者: Nmda-Receptor    時(shí)間: 2025-3-26 15:43
Nina P. Kirchner,Kolumban Huttertors and other nuclear receptors has been reported (Chen .., 1997c Lee .., 1999 Panet-Raymand .., 2000). The type 1 nuclear receptors typically bind to DNA response elements organized as inverted repeats (Mangelsdorf .., 1995). The type 2 nuclear receptors dimerize with the 9-. retinoic acid recepto
作者: 用手捏    時(shí)間: 2025-3-26 18:46

作者: 豐富    時(shí)間: 2025-3-26 23:37
Yury A. Rossikhin,Marina V. Shitikovaks second among cancer-related male deaths in the United States (.). PCa is detected histologically in a latent form in approximately 30% of men over the age of 50 and in 60-70% of men over the age of 80, but becomes clinically evident in 10-15% of American men during their lifetime (.).
作者: 增減字母法    時(shí)間: 2025-3-27 03:48
Routing in Telephone and Data Networks,utamines (Poly-Q) in the respective protein. Thus, CAG repeat diseases are also called Poly-Q diseases. The Poly-Q diseases have different disease-causing genes, suggesting that these disorders share a common pathogenesis involving the gain of a toxic function associated with the expanded Poly-Q tra
作者: 用樹皮    時(shí)間: 2025-3-27 05:23
Protecting Against SQL Injection,d that AR may function without binding to DNA (.). AR is expressed nearly ubiquitously in mammalian tissues (.; .; .), and is known to play various biological roles in areas including development, sexual and reproductive function, immune function, and homeostasis (Quigley, 1998).
作者: chemical-peel    時(shí)間: 2025-3-27 10:29

作者: Hemodialysis    時(shí)間: 2025-3-27 15:32

作者: 淺灘    時(shí)間: 2025-3-27 19:50

作者: 周興旺    時(shí)間: 2025-3-28 00:55

作者: 剝削    時(shí)間: 2025-3-28 04:25

作者: 萬花筒    時(shí)間: 2025-3-28 07:43
Androgens in Prostate Cancer and Benign Prostatic Hyperplasia,ks second among cancer-related male deaths in the United States (.). PCa is detected histologically in a latent form in approximately 30% of men over the age of 50 and in 60-70% of men over the age of 80, but becomes clinically evident in 10-15% of American men during their lifetime (.).
作者: MAL    時(shí)間: 2025-3-28 14:28

作者: Aerate    時(shí)間: 2025-3-28 18:32

作者: 出沒    時(shí)間: 2025-3-28 21:22
Androgens and Coronary Artery Disease,angina pectoris, and angiographic assessment of atherosclerosis? 2. Which effects on coronary endpoints or symptoms are exerted by application of exogenous testosterone (T) or suppression of endogenous T? 3. What can be learned from animal studies of the effects of androgens on atherosclerosis? 4. H
作者: anatomical    時(shí)間: 2025-3-29 00:00

作者: 裙帶關(guān)系    時(shí)間: 2025-3-29 04:42
Androgens and Androgen Receptor in Dermatology,receptors (such as with the SRC family) (.) or more specific for AR (reviewed in Heinlein, .., Chapter 4). These AR coregulators can enhance AR transactivation through different kinds of mechanisms including enhancing ligand binding (i.e. ARA70) (Ting and Chang, unpublished observations), enhancing
作者: 獨(dú)白    時(shí)間: 2025-3-29 10:39
Androgen Biosynthesis And Degradation,lating T also plays an important role in the hypothalamus-pituitary-testis loop to maintain proper amounts of sex steroids. The regulation of androgen production will be detailed in the following section.
作者: debacle    時(shí)間: 2025-3-29 14:04
Androgen Receptor Interacting Proteins: Co-Activators And Co-Repressors,transcriptional activity after ligand binding, may result in male infertility, or complete or partial androgen insensitivity (.; .; .; .; .). Somatic AR mutations have also been identified in some prostate tumors (Bentel and Tilley, 1996).
作者: Lipoprotein    時(shí)間: 2025-3-29 16:14

作者: Pelago    時(shí)間: 2025-3-29 23:17
Agnieszka Chrzanowska,Harald Ehrentrauttranscriptional activity after ligand binding, may result in male infertility, or complete or partial androgen insensitivity (.; .; .; .; .). Somatic AR mutations have also been identified in some prostate tumors (Bentel and Tilley, 1996).
作者: 小官    時(shí)間: 2025-3-30 01:40
Book 2002receptor actions, their roles in the androgen-related diseases, and their potential clinical applications..Key topics covered include: .-The discovery and cloning of the androgen receptor; .-Androgen receptor coregulators; .-Androgen related genes and their consensus DNA response elements; .-Basic m
作者: Dissonance    時(shí)間: 2025-3-30 04:26

作者: 柔美流暢    時(shí)間: 2025-3-30 08:44
Book 2002; .-The recent connections of androgens to women‘s diseases, such as osteoporosis and ovarian cancer..This book is of interest to students, basic scientists, and clinicians as both a study guide and reference of research in the androgen field. It could also be used as an advanced level text in endocrinology, urology, OBGYN, or oncology.
作者: CESS    時(shí)間: 2025-3-30 12:53
David Kampenhuber,Christoph Adamators to promote the expression of target genes (.; .; .; .). In addition to this transcriptional or genomic mode of action by steroids, an increasing body of evidence suggests that androgens, as well as progesterone and estrogen, can exert rapid, nongenomic effects (.; .; .).
作者: erythema    時(shí)間: 2025-3-30 18:58

作者: 豐富    時(shí)間: 2025-3-30 20:55
Theoretical Concepts of Lasers,cile. The practice was employed in part as a marketing tool, since the Greeks sold eunuch slaves in cities such as Ephesus and Sardis. Even in the time of Herodotus, the practice was long-standing, reflected in his notation that castration of male servants was a Persian custom at the time.
作者: pineal-gland    時(shí)間: 2025-3-31 01:34

作者: 一起    時(shí)間: 2025-3-31 06:04
Androgens in Immunology and Autoimmune Diseases,ss and prevent autoimmune disease or attenuate its progression, while estrogenic hormones have opposite effects. This chapter will present an overview of androgen-mediated effects on host immune defense and autoimmune disorders.
作者: 內(nèi)向者    時(shí)間: 2025-3-31 11:26

作者: 柔軟    時(shí)間: 2025-3-31 14:35
Harald Ehrentraut,Agnieszka Chrzanowskacription factors or transcription factor interacting proteins. In the prostate, AR is among the transcription factors whose activity is influenced by signal transduction cascades and disruption of the normal interaction between signal transduction and AR transactivation may contribute to the progression of prostate cancer.
作者: 基因組    時(shí)間: 2025-3-31 20:49
https://doi.org/10.1007/978-1-4615-0251-7ncy, and 2) defects in androgen action. The second category includes 5α-reductase deficiency (pseudovaginal perineoscrotal hypospadias) and androgen insensitivity (or resistance) syndrome. Formerly, the severest type of the androgen insensitivity syndrome was called testicular feminization syndrome.
作者: PET-scan    時(shí)間: 2025-3-31 21:47

作者: cancer    時(shí)間: 2025-4-1 04:22
Androgen Insensitivity Syndrome (Testicular Feminization),ncy, and 2) defects in androgen action. The second category includes 5α-reductase deficiency (pseudovaginal perineoscrotal hypospadias) and androgen insensitivity (or resistance) syndrome. Formerly, the severest type of the androgen insensitivity syndrome was called testicular feminization syndrome.
作者: Free-Radical    時(shí)間: 2025-4-1 06:55

作者: Breach    時(shí)間: 2025-4-1 11:37
Structural and Functional Analysis of the Androgen Receptor,ediate the expression of target genes in response to ligands specific to each receptor, including steroids, retinoids, vitamin D, and thyroid hormone. Members of the nuclear receptor superfamily all share a common structure composed of an NH.-terminal transactivation domain and DNA and ligand bindin




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