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標(biāo)題: Titlebook: Analytical Techniques in the Pharmaceutical Sciences; Anette Müllertz,Yvonne Perrie,Thomas Rades Book 2016 Springer Science+Business Media [打印本頁(yè)]

作者: negation    時(shí)間: 2025-3-21 18:38
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作者: 一條卷發(fā)    時(shí)間: 2025-3-21 21:26
Fluorescence Spectroscopy: Basic Foundations and Methodsdevelopments on distinct fluorescence methods, particularly those related to the study of biological phenomena. This chapter discusses the foundations of the fluorescence phenomenon, introduces some general methodologies and provides selected examples on applications focused to disentangle structura
作者: VEN    時(shí)間: 2025-3-22 03:02

作者: Bucket    時(shí)間: 2025-3-22 07:42
Raman Spectroscopyed along with some of the key issues in measuring Raman spectra that may be relevant to pharmaceutical samples. The limitations and strengths of different instruments (dispersive and Fourier-transform) are described. The use of Raman spectroscopy is highlighted in a number of case studies that utili
作者: 改變    時(shí)間: 2025-3-22 11:24
Pharmaceutical Terahertz Spectroscopy and Imaging systems. In this chapter the technology that has enabled the recent surge of interest in using terahertz techniques is explained in terms of its basic principles and the specific implementations of pharmaceutical relevance. Using a number of examples and case studies an overview of the current stat
作者: Cuisine    時(shí)間: 2025-3-22 14:40
Circular Dichroism Spectroscopy for Structural Characterization of Proteins First, the native structure of a given protein drug molecule must be characterized in order to define the active compound. Next, for the successful development of a formulation or drug delivery system for said molecule, compatibility of the system with the protein should be demonstrated. This is a
作者: Bronchial-Tubes    時(shí)間: 2025-3-22 18:47
Applications of Mass Spectrometry in Drug Development Scienceo a premier analytical tool in drug development science. Through specific MS-based workflows including customized sample preparation, coupling to liquid chromatography and different ionization principles, both qualitative and quantitative analysis of small and large drug compounds can be achieved at
作者: 自傳    時(shí)間: 2025-3-22 22:22

作者: Root494    時(shí)間: 2025-3-23 03:17

作者: Adrenal-Glands    時(shí)間: 2025-3-23 07:47
Applications of Small Angle X-ray Scattering in Pharmaceutical Science. This contribution aims to highlight a range of areas in which SAXS can be deployed to better understand structure in pharmaceutically relevant materials from molecular to colloidal dimensions, with a focus on developing synchrotron techniques that provide new opportunities in time resolved kinetic
作者: 聯(lián)想記憶    時(shí)間: 2025-3-23 12:42
Thermal Analysis of Pharmaceuticalsonventional thermal methods all involve measuring a response from a material (usually in the form of energy/temperature or mass changes) as a result of applying heat to the sample. In this chapter the most widely used thermal analytical methods along with some more recently developed local thermal a
作者: 分發(fā)    時(shí)間: 2025-3-23 16:00
Isothermal Microcalorimetryd physical, occur with a change in heat, IMC analysis can be applied to the investigation of almost any material. The inherent sensitivity of the measurement means that small samples, or slow processes, may be investigated. This makes IMC a very powerful tool, especially in pharmaceutical analyses,
作者: Frisky    時(shí)間: 2025-3-23 20:15
HPLC/UHPLCimportant to verify that a compound developed in the initial research phase primarily contain the expected compound and not a number of major impurities that may be responsible for effect or side effects, but even a “pure” API do always contain minor impurities which have to be controlled. The formu
作者: 偏見    時(shí)間: 2025-3-24 00:18

作者: convulsion    時(shí)間: 2025-3-24 05:15
Asymmetrical Flow Field Flow Fractionation: A Useful Tool for the Separation of Protein Pharmaceuticls and particulate systems. The chapter will provide some background and historical information on field flow fractionation and the general working principle. In addition, a practical guide on how to use AF4 will be described and critical parameters for the development of a suitable separation metho
作者: Bumble    時(shí)間: 2025-3-24 09:13

作者: abysmal    時(shí)間: 2025-3-24 11:09
Analytical Techniques in the Pharmaceutical Sciences
作者: 不確定    時(shí)間: 2025-3-24 16:48
2192-6204 ropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system978-1-4939-8158-8978-1-4939-4029-5Series ISSN 2192-6204 Series E-ISSN 2192-6212
作者: BUDGE    時(shí)間: 2025-3-24 20:55

作者: 光亮    時(shí)間: 2025-3-25 01:44
Lecture Notes in Networks and Systemsn of the instrumentation, several specific examples of applications and general experimental recommendations for CD experiments, including a special perspective on challenging samples as may be encountered in pharmaceutical sciences.
作者: Certainty    時(shí)間: 2025-3-25 06:00
Conclusions and Future Research,ure analysis of proteins by mass spectrometry will be given as well as related workflows for quantitative MS analysis. Established “top-down” and “bottom-up” protein analyses with MS will be recapitulated, and the use of emerging technologies such as hydrogen/deuterium exchange mass spectrometry (HD
作者: 黑豹    時(shí)間: 2025-3-25 11:31

作者: 得罪    時(shí)間: 2025-3-25 12:20

作者: PET-scan    時(shí)間: 2025-3-25 16:10

作者: Malleable    時(shí)間: 2025-3-25 21:45

作者: AGONY    時(shí)間: 2025-3-26 03:20
Applications of Mass Spectrometry in Drug Development Scienceure analysis of proteins by mass spectrometry will be given as well as related workflows for quantitative MS analysis. Established “top-down” and “bottom-up” protein analyses with MS will be recapitulated, and the use of emerging technologies such as hydrogen/deuterium exchange mass spectrometry (HD
作者: 加強(qiáng)防衛(wèi)    時(shí)間: 2025-3-26 05:18
HPLC/UHPLC chromatography is most useful for such qualitative and quantitative analysis and is performed using high performance liquid chromatography (HPLC) or ultra high performance liquid chromatography equipment (UHPLC). Using these techniques high efficiency separations are achieved, and in this chapter t
作者: Fibrin    時(shí)間: 2025-3-26 11:51
Capillary-Based Techniques for Physical-Chemical Characterization of Drug Substances and Drug Delivedrodynamic radius as well as viscosity. A variant of this technique termed Flow Induced Dispersion Analysis (FIDA) may be used to quantify non-covalent affinity interactions for charged as well as neutral species. The present chapter highlights novel features of capillary based methods in profiling
作者: miniature    時(shí)間: 2025-3-26 14:27

作者: 鞏固    時(shí)間: 2025-3-26 19:26
Lecture Notes in Networks and Systemsze multivariate techniques; polymorphism, drug delivery and counterfeit drug studies are described. Finally, new technologies that are set to further enhance Raman spectroscopy as a method for analysis, such as low frequency Raman, spatially offset Raman scattering, transmission Raman and spatial heterodyne Raman spectroscopy are discussed.
作者: 影響帶來(lái)    時(shí)間: 2025-3-26 21:43
Handlungskonzepte in disruptiver Innovation,ch it can be used to probe crystal structures, with a particular emphasis on the practicalities of data collection in the laboratory and on data analysis, leading ultimately to high-quality, refined crystal structures.
作者: 假設(shè)    時(shí)間: 2025-3-27 03:51
Thomas W. Flanagan,Charles D. Nicholsd will be discussed. The use of AF4 for protein pharmaceuticals as well as particulate systems will be described and some examples given in the literature will be presented. Finally, a summary of the most recent trends in AF4 and an outlook will be given for potential application fields in the future.
作者: 不妥協(xié)    時(shí)間: 2025-3-27 07:40

作者: 愛花花兒憤怒    時(shí)間: 2025-3-27 10:35

作者: entrance    時(shí)間: 2025-3-27 15:41
https://doi.org/10.1007/978-1-4614-3058-2l arrangements are defined and applications to pharmaceutical analyses are discussed. Applications discussed progress from preformulation characterization, through stability testing and amorphous content quantification to analyses of formulated products.
作者: 變形詞    時(shí)間: 2025-3-27 19:20
Pharmaceutical Terahertz Spectroscopy and Imagingquantification, detailed analysis of phase transitions to amorphous stability. Important imaging applications include non-destructive coating thickness measurements, characterisation of the microstructure of tablet matrices as well as liquid transport into tablets during disintegration.
作者: appall    時(shí)間: 2025-3-27 22:08
Single-Crystal X-ray Diffractionspects that, in the author’s opinion, should still be understood to measure crystallographic data effectively and to interpret crystallographic results. The focus is on selected topics that are likely to be most relevant to pharmaceutical solid-form characterization.
作者: 高歌    時(shí)間: 2025-3-28 05:52
Isothermal Microcalorimetryl arrangements are defined and applications to pharmaceutical analyses are discussed. Applications discussed progress from preformulation characterization, through stability testing and amorphous content quantification to analyses of formulated products.
作者: figure    時(shí)間: 2025-3-28 09:28

作者: dainty    時(shí)間: 2025-3-28 14:17
Raman Spectroscopyze multivariate techniques; polymorphism, drug delivery and counterfeit drug studies are described. Finally, new technologies that are set to further enhance Raman spectroscopy as a method for analysis, such as low frequency Raman, spatially offset Raman scattering, transmission Raman and spatial heterodyne Raman spectroscopy are discussed.
作者: 羅盤    時(shí)間: 2025-3-28 15:46
An Overview of Powder X-ray Diffraction and Its Relevance to Pharmaceutical Crystal Structuresch it can be used to probe crystal structures, with a particular emphasis on the practicalities of data collection in the laboratory and on data analysis, leading ultimately to high-quality, refined crystal structures.
作者: 凹槽    時(shí)間: 2025-3-28 22:07
Asymmetrical Flow Field Flow Fractionation: A Useful Tool for the Separation of Protein Pharmaceuticd will be discussed. The use of AF4 for protein pharmaceuticals as well as particulate systems will be described and some examples given in the literature will be presented. Finally, a summary of the most recent trends in AF4 and an outlook will be given for potential application fields in the future.
作者: 媽媽不開心    時(shí)間: 2025-3-29 02:18
Disruptive Healthcare Provider Behaviorhotometry for compound identification and physicochemical profiling, including pK. and kinetic studies. Recent UV imaging equipment facilitating spatially (2D) resolved absorbance measurements in real-time is described and selected applications in drug dissolution and release testing reviewed.
作者: 聯(lián)想記憶    時(shí)間: 2025-3-29 05:03

作者: Synapse    時(shí)間: 2025-3-29 07:36

作者: 新陳代謝    時(shí)間: 2025-3-29 12:31
Thermal Analysis of Pharmaceuticalsventional bulk sample analysis to also allowing more localized micron to sub-micron scale distribution and compositional analysis. The limitations of thermal methods for different applications are also discussed in relation to other characterization methods.
作者: FEMUR    時(shí)間: 2025-3-29 17:19

作者: cancer    時(shí)間: 2025-3-29 21:52
Rule-Based System for Pregnancy Monitoringdevelopments on distinct fluorescence methods, particularly those related to the study of biological phenomena. This chapter discusses the foundations of the fluorescence phenomenon, introduces some general methodologies and provides selected examples on applications focused to disentangle structural and dynamical aspects of biological processes.
作者: 相反放置    時(shí)間: 2025-3-30 03:49
https://doi.org/10.1007/978-1-4614-3058-2. This contribution aims to highlight a range of areas in which SAXS can be deployed to better understand structure in pharmaceutically relevant materials from molecular to colloidal dimensions, with a focus on developing synchrotron techniques that provide new opportunities in time resolved kinetic studies.
作者: 永久    時(shí)間: 2025-3-30 06:12

作者: Engulf    時(shí)間: 2025-3-30 10:50

作者: 向下    時(shí)間: 2025-3-30 14:48

作者: 拍翅    時(shí)間: 2025-3-30 20:02
Advances in Delivery Science and Technologyhttp://image.papertrans.cn/a/image/156670.jpg
作者: 羽飾    時(shí)間: 2025-3-30 22:56
https://doi.org/10.1007/978-1-4939-4029-5analysis; imaging; rheology; spectroscopy; drug discovery; diffractometric
作者: handle    時(shí)間: 2025-3-31 02:17

作者: 消極詞匯    時(shí)間: 2025-3-31 08:25
Disruptive Healthcare Provider Behaviorght as a function of wavelength depends on the structural properties of molecules as well as the solvent in which they are dissolved, including solvent polarity, pH, temperature and the presence of complexing agents. The absorbance measured for an analyte can be linearly related to concentration thr
作者: 侵略    時(shí)間: 2025-3-31 12:36

作者: 低三下四之人    時(shí)間: 2025-3-31 17:07
Aleksander Aristovnik,Lan Umek,Dejan Rav?eljsents many interesting perspectives in both qualitative and quantitative analysis. These two techniques are powerful analytical tools for the identification and molecular characterization of pharmaceutical raw materials, intermediates and final dosage forms. NIR spectroscopy being fast, noninvasive,
作者: ANA    時(shí)間: 2025-3-31 20:42
Lecture Notes in Networks and Systemsed along with some of the key issues in measuring Raman spectra that may be relevant to pharmaceutical samples. The limitations and strengths of different instruments (dispersive and Fourier-transform) are described. The use of Raman spectroscopy is highlighted in a number of case studies that utili




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