標題: Titlebook: Analgesia; Christoph Stein Book 2007 Springer-Verlag Berlin Heidelberg 2007 Arthritis.Cancer.Cannabinoid.Headache.Inflammation.Opioid.Pain [打印本頁] 作者: lexicographer 時間: 2025-3-21 17:57
書目名稱Analgesia影響因子(影響力)
書目名稱Analgesia影響因子(影響力)學科排名
書目名稱Analgesia網(wǎng)絡公開度
書目名稱Analgesia網(wǎng)絡公開度學科排名
書目名稱Analgesia被引頻次
書目名稱Analgesia被引頻次學科排名
書目名稱Analgesia年度引用
書目名稱Analgesia年度引用學科排名
書目名稱Analgesia讀者反饋
書目名稱Analgesia讀者反饋學科排名
作者: capsule 時間: 2025-3-21 21:53 作者: 使熄滅 時間: 2025-3-22 03:02
https://doi.org/10.1007/978-3-662-33072-2kinins have a pathophysiological role in nociception. Clinical studies with non-peptide pharmacological antagonists are now in progress to determine if blocking the action of these peptides might have utility in the treatment of pain.作者: GROUP 時間: 2025-3-22 08:19
https://doi.org/10.1007/978-3-642-97695-7of P2X. receptors may be useful for relieving inflammatory and neuropathic pain. More recently, data have begun to emerge implicating P2X., P2X. and P2Y receptors in aspects of pain transmission. Both P1 and P2 receptors may represent novel targets for pain relief.作者: insurrection 時間: 2025-3-22 10:39 作者: 乳白光 時間: 2025-3-22 13:25
Neuropeptide and Kinin Antagonistskinins have a pathophysiological role in nociception. Clinical studies with non-peptide pharmacological antagonists are now in progress to determine if blocking the action of these peptides might have utility in the treatment of pain.作者: 阻擋 時間: 2025-3-22 17:26
Adenosine and ATP Receptorsof P2X. receptors may be useful for relieving inflammatory and neuropathic pain. More recently, data have begun to emerge implicating P2X., P2X. and P2Y receptors in aspects of pain transmission. Both P1 and P2 receptors may represent novel targets for pain relief.作者: figurine 時間: 2025-3-23 00:28
Opioidsg, cAMP inhibition, Ca. channel inhibition) have been described. The differential regulation of effectors, preclinical pharmacology, clinical applications, and side effects will be reviewed in this chapter.作者: Eructation 時間: 2025-3-23 03:34
Antipyretic Analgesics: Nonsteroidal Antiinflammatory Drugs, Selective COX-2 Inhibitors, Paracetamolese drugs with particular emphasis on their rational use based on the diverse pharmacokinetic characteristics and adverse drug reaction profiles. Referring to the current debate, potential mechanisms underlying cardiovascular side effects associated with long-term use of COX inhibitors are discussed.作者: cardiac-arrest 時間: 2025-3-23 07:55 作者: 別名 時間: 2025-3-23 11:02
0171-2004 eriansisolatedopioids(probablyfortheir euphoric effects) in the third millennium b. c. and the use of willow bark (salicin) for fever was ?rst reported in the eighteenth century. Both types of drugs are still in use, but today they are supplemented by a wide array of substances ranging from antidepr作者: abreast 時間: 2025-3-23 16:15 作者: 孤獨無助 時間: 2025-3-23 19:25
https://doi.org/10.1007/978-3-642-97695-7nsitivity of peripheral neurons to change pain thresholds. This chapter details the evidence that individual channels may be associated with particular pain states, and describes genetic approaches to test the possible utility of targeting individual channels to treat pain.作者: plasma-cells 時間: 2025-3-24 00:09
Adrenergic and Cholinergic Compoundsor both current application and future development of these agents. Nicotinic and muscarinic cholinergic ligands represent a novel class of agents with much promise for the management of problematic pain. In this chapter we review advances in both preclinical and clinical arenas and highlight potential avenues for further research.作者: Statins 時間: 2025-3-24 02:34
Ion Channels in Analgesia Researchnsitivity of peripheral neurons to change pain thresholds. This chapter details the evidence that individual channels may be associated with particular pain states, and describes genetic approaches to test the possible utility of targeting individual channels to treat pain.作者: 搖晃 時間: 2025-3-24 10:21 作者: figure 時間: 2025-3-24 14:28 作者: Indict 時間: 2025-3-24 17:42 作者: 慢慢流出 時間: 2025-3-24 20:36
https://doi.org/10.1007/978-3-642-97695-7is endogenous opioid network is naturally activated in humans. Therefore, not only is placebo research helpful towards improving clinical trial design and medical practice, but it also provides us with a better understanding of the endogenous mechanisms of analgesia.作者: 用樹皮 時間: 2025-3-25 01:07 作者: 我不死扛 時間: 2025-3-25 05:08
Book 2007ons in clinical use. It also gives - sights into current efforts to discover novel mechanisms underlying different types of pain generation and the resulting development of new modulating compounds. Theseefforts haveemergedmostlyas aconsequenceofthemore profound insights provided by molecular method作者: 同步左右 時間: 2025-3-25 07:53
0171-2004 fferent types of pain generation and the resulting development of new modulating compounds. Theseefforts haveemergedmostlyas aconsequenceofthemore profound insights provided by molecular method978-3-642-43931-5978-3-540-33823-9Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: 個阿姨勾引你 時間: 2025-3-25 12:05 作者: Cantankerous 時間: 2025-3-25 17:41 作者: 殘忍 時間: 2025-3-25 21:06 作者: textile 時間: 2025-3-26 03:10 作者: Musculoskeletal 時間: 2025-3-26 05:20 作者: occurrence 時間: 2025-3-26 09:37 作者: 尖牙 時間: 2025-3-26 16:36 作者: Mortal 時間: 2025-3-26 17:52
https://doi.org/10.1007/978-3-662-33073-9 and mexiletine, all anti-convulsants. A better understanding of ion channels at the sites of injury has shown important roles of particular sodium, potassium and calcium channels in the genesis of neuropathic pain. Within the spinal cord, increases in the activity of calcium channels and the recept作者: 犬儒主義者 時間: 2025-3-26 22:23
https://doi.org/10.1007/978-3-642-97695-7lay a role in the analgesic effects of cannabinoids. In contrast, the clinical effectiveness of cannabinoids as analgesics is less clear. Progress in this area requires the development of cannabinoids with a more favourable therapeutic index than those currently available for human use, and the test作者: PLIC 時間: 2025-3-27 01:15
https://doi.org/10.1007/978-3-642-97695-7cade have demonstrated important roles of these kinases in regulating neuronal plasticity and pain sensitization. Multiple protein kinases have been implicated in peripheral and central sensitization following intense noxious stimuli and injuries. In particular, mitogen-activated protein kinases (MA作者: plasma-cells 時間: 2025-3-27 06:10 作者: 潛伏期 時間: 2025-3-27 10:57
Opioidsndogenous ligands (opioid peptides) are known. The standard exogenous opioid analgesic is morphine. Opioid agonists can activate central and peripheral opioid receptors. Three classes of opioid receptors (μ, δ, κ) have been identified. Multiple pathways of opioid receptor signaling (e.g., G. couplin作者: Constrain 時間: 2025-3-27 16:57 作者: 腫塊 時間: 2025-3-27 21:35 作者: 突襲 時間: 2025-3-27 23:08
Serotonin Receptor Ligands: Treatments of Acute Migraine and Cluster Headachet of acute migraine and cluster headache. Sumatriptan was the first of these agonists, and it launched a wave of therapeutic advances. These medicines are effective and safe. Triptans were developed as cranial vasoconstrictors to mimic the desirable effects of serotonin, while avoiding its side-effe作者: FRET 時間: 2025-3-28 04:15 作者: MURAL 時間: 2025-3-28 07:54
Neuropeptide and Kinin Antagonistsn the substances themselves are administered, to animals or to human subjects—a significant number of them have been suggested to have a role in pain and inflammation. Experiments in gene deletion (knock-out or null mutant) mice and parallel experiments with pharmacological receptor antagonists in a作者: defenses 時間: 2025-3-28 11:37 作者: 使饑餓 時間: 2025-3-28 17:17
Adrenergic and Cholinergic Compounds-established analgesic profile; however, recent investigations suggest that this class of agents is underused, and herein we highlight the potential for both current application and future development of these agents. Nicotinic and muscarinic cholinergic ligands represent a novel class of agents wit作者: 察覺 時間: 2025-3-28 19:50
Cannabinoids and Pains. The anatomical and functional data reveal cannabinoid receptor-mediated analgesic actions operating at sites concerned with the transmission and processing of nociceptive signals in brain, spinal cord and the periphery. The precise signalling mechanisms by which cannabinoids produce analgesic eff作者: 愛好 時間: 2025-3-29 01:39
Adenosine and ATP Receptorsions. Such influences reflect peripheral and central actions and effects on neurons as well as other cell types. In general, adenosine A1 receptors produce inhibitory effects on pain in a number of preclinical models and are a focus of attention. In humans, i.v. infusions of adenosine reduce some as作者: BROTH 時間: 2025-3-29 04:40
Ion Channels in Analgesia Researchmolecular nature of the channels that are activated by tissue-damaging stimuli, as well as the mechanisms by which voltage-gated channels alter the sensitivity of peripheral neurons to change pain thresholds. This chapter details the evidence that individual channels may be associated with particula作者: 狗窩 時間: 2025-3-29 08:03
Protein Kinases as Potential Targets for the Treatment of Pathological Painathological pain is an expression of neural plasticity that occurs both in the peripheral nervous system (e.g., primary sensory nociceptors), termed peripheral sensitization, and in the central nervous system (e.g., dorsal horn and brain neurons), termed central sensitization. Our insufficient under作者: Ornament 時間: 2025-3-29 13:11 作者: 6Applepolish 時間: 2025-3-29 19:13
Christoph SteinIncludes supplementary material: 作者: 泰然自若 時間: 2025-3-29 22:16
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/a/image/155791.jpg作者: 增長 時間: 2025-3-30 02:34
Analgesia978-3-540-33823-9Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: 單調(diào)女 時間: 2025-3-30 07:02
Bernhard Ebbinghaus,Jelle Visserortantly, both the peripheral and the central nociceptive system contribute significantly to the generation of pain upon inflammation and nerve injury. Peripheral nociceptors are sensitized during inflammation, and peripheral nerve fibres develop ectopic discharges upon nerve injury or disease. As a作者: inflate 時間: 2025-3-30 11:44 作者: 細微的差異 時間: 2025-3-30 16:09
https://doi.org/10.1007/978-3-322-95979-9ol, pyrazolinones) drugs. Moreover, various selective cyclooxygenase-2 (COX-2) inhibitors with improved gastrointestinal tolerability as compared with conventional NSAIDs have been established for symptomatic pain treatment in recent years. The present review summarizes the pharmacology of all of th作者: flourish 時間: 2025-3-30 18:51
https://doi.org/10.1007/978-3-322-95979-9l anesthetics, reviews their broad actions that affect many different molecular targets and disrupt their functions in pain processing. Application of local anesthetics to peripheral nerve primarily results in the blockade of propagating action potentials, through their inhibition of voltage-gated s作者: fixed-joint 時間: 2025-3-30 22:30
