標(biāo)題: Titlebook: An Introduction to Toxicology; Philip C. Burcham Textbook 2014 Springer-Verlag London 2014 Apoptosis.carcinogen.epidemiology.organ.tobacco [打印本頁(yè)] 作者: Extraneous 時(shí)間: 2025-3-21 19:03
書目名稱An Introduction to Toxicology影響因子(影響力)
書目名稱An Introduction to Toxicology影響因子(影響力)學(xué)科排名
書目名稱An Introduction to Toxicology網(wǎng)絡(luò)公開度
書目名稱An Introduction to Toxicology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱An Introduction to Toxicology被引頻次
書目名稱An Introduction to Toxicology被引頻次學(xué)科排名
書目名稱An Introduction to Toxicology年度引用
書目名稱An Introduction to Toxicology年度引用學(xué)科排名
書目名稱An Introduction to Toxicology讀者反饋
書目名稱An Introduction to Toxicology讀者反饋學(xué)科排名
作者: 無價(jià)值 時(shí)間: 2025-3-21 20:51
ext.The author is an academic researcher with extensive teac.This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest 作者: 凝結(jié)劑 時(shí)間: 2025-3-22 02:11 作者: 撫慰 時(shí)間: 2025-3-22 04:59 作者: 緊張過度 時(shí)間: 2025-3-22 10:41
Second Opinion bei Instabilit?tsomarthrose electrophile. Alcohol also undergoes nonoxidative metabolism to form such conjugative metabolites as ethyl-glucuronide, ethyl-sulfate and fatty acid ethyl esters. These metabolites find growing use as biomarkers of alcohol intake and appear especially useful during the diagnosis of foetal alcohol syndrome.作者: 多余 時(shí)間: 2025-3-22 14:35
Core Concepts in Toxicology,ctions between chemicals in complex ‘real-world’ exposure scenarios involving simultaneous exposure to more than one substance is also considered. The role of lifestyle factors in shaping individual susceptibility to chemical toxicity is also highlighted, as is the timing of the manifestation of toxicity following toxicant exposure.作者: Supplement 時(shí)間: 2025-3-22 17:11
Target-Organ Toxicity: Liver and Kidney,ty, while also surveying typical toxic responses in these organs (e.g. steatosis, fibrosis, cancer). The diverse mechanisms underlying excretory organ toxicity are illustrated for such classic toxicants as azidothymidine, carbon tetrachloride, paracetamol, troglitazone, cylindrospermopsin and trichloroethylene.作者: Small-Intestine 時(shí)間: 2025-3-22 21:13 作者: 個(gè)阿姨勾引你 時(shí)間: 2025-3-23 01:46 作者: Aggrandize 時(shí)間: 2025-3-23 07:16
978-1-4471-7256-7Springer-Verlag London 2014作者: 嚴(yán)重傷害 時(shí)間: 2025-3-23 13:37 作者: 壕溝 時(shí)間: 2025-3-23 16:41
https://doi.org/10.1007/978-94-010-3712-9eeded for the types of substances that are of concern to toxicologists, this chapter explores linguistic nuances surrounding such words as poison, toxin, xenobiotic, endobiotic and toxicant. Next, the complications that can accompany study of toxicity due to differences in the duration of chemical e作者: 鉗子 時(shí)間: 2025-3-23 19:11
Zwischen Arbeitsamt und Ehrenamt processes dictate the ‘toxicokinetic fate’ of a xenobiotic – describing how it penetrates cell barriers to enter tissues (i.e. absorption), whether it is dispersed to particular organs and tissue compartments (distribution), how it undergoes chemical transformation within the liver (metabolism) and作者: 有抱負(fù)者 時(shí)間: 2025-3-23 23:30
Hubert Heinelt,Carl-Wilhelm Macke upon thousands of metabolites, genes, proteins and interconnected signalling networks – is a central concern in modern toxicology. While toxicologists were long restricted to observational descriptions of morphological changes in dying cells, modern developments in chemistry and molecular biology o作者: 完成才能戰(zhàn)勝 時(shí)間: 2025-3-24 04:02
Die Entzauberung der Berliner Sozialpolitikperienced a dramatic loss of effectiveness, with higher and higher doses required to elicit the original drug response. This capacity for physical tolerance alerted researchers to the phenomenon of enzyme induction: upon sustained exposure, the liver and other tissues simultaneously boost the expres作者: interpose 時(shí)間: 2025-3-24 10:08 作者: 擴(kuò)大 時(shí)間: 2025-3-24 12:06
https://doi.org/10.1007/978-3-642-37094-6in a mother’s blood. In subsequent decades, knowledge of the risks accompanying exposure to developmental toxicants increased substantially. According to long-standing observations, substances that harm the unborn typically produce a combination of three toxic outcomes, namely, growth retardation, e作者: Mediocre 時(shí)間: 2025-3-24 16:17
Rainer Peter Meyer,Fabrizio Moro,Beat Simmenses possessing unstable genomes and aggressive tendencies to invade local tissue or metastasise to remote sites. Since the accumulation of mutations in critical genes typically underpins these harmful capabilities, modern toxicology devotes much effort to identifying chemicals that cause mutations. 作者: vasospasm 時(shí)間: 2025-3-24 21:06
Second Opinion bei Instabilit?tsomarthrose systems. The resulting health disorders are classified according to whether they are ‘partly’ or ‘wholly’ attributable to alcohol. The former include hypertension and breast cancer, while those in the latter category, which typically attract most toxicological attention, include alcoholic liver dis作者: Receive 時(shí)間: 2025-3-25 01:12
Second Opinion bei Instabilit?tsomarthrosehealth disorders accompany this habit including various cancers plus noncancer conditions such as emphysema. The smoke constituents causing lung injury have received much attention, with special interest focussed on carcinogens that drive the induction and progression of lung cancer. Major carcinoge作者: Veneer 時(shí)間: 2025-3-25 04:44 作者: 破譯密碼 時(shí)間: 2025-3-25 08:26 作者: hegemony 時(shí)間: 2025-3-25 14:49
Die Zweidimensionale Laplace-Transformation than the thalidomide disaster of the early 1960s. A flurry of activity saw toxicology-focussed societies, journals, regulatory agencies and research institutions established around the world. Toxicology today is a highly evolved, multidisciplinary endeavour that develops its own conceptual framewor作者: 殘忍 時(shí)間: 2025-3-25 17:55
Zwischen Arbeitsamt und Ehrenamts – in controlling the disposition of ingested chemicals. The possibility that one chemical might alter the ability of these proteins to metabolise or export another xenobiotic is also briefly considered (i.e. toxicant interactions).作者: enfeeble 時(shí)間: 2025-3-25 22:21
Hubert Heinelt,Carl-Wilhelm Mackee-catalysed conversion to electrophilic metabolites that react chemically with cell macromolecules. This chapter explores the basic properties of reactive metabolites that influence their toxicological properties together with the major deleterious consequences of reactive metabolite formation withi作者: 外表讀作 時(shí)間: 2025-3-26 00:21 作者: Thyroiditis 時(shí)間: 2025-3-26 04:59 作者: Dislocation 時(shí)間: 2025-3-26 10:50
Rainer Peter Meyer,Fabrizio Moro,Beat Simmenpts are reinforced by studying the toxicology of known human carcinogens (e.g. vinyl chloride, asbestos and aristolochic acid) as well as chemicals with a still unclear role in human cancer (e.g. acrylamide).作者: Colonoscopy 時(shí)間: 2025-3-26 14:34
Second Opinion bei Instabilit?tsomarthroseNNN and NNK undergo CYP-catalysed bioactivation to DNA-damaging metabolites. DNA adducts formed by these and other noxious metabolites drive the accumulation of mutations in growth regulatory genes within the smokers’ lung.作者: 灰姑娘 時(shí)間: 2025-3-26 17:05 作者: 使饑餓 時(shí)間: 2025-3-26 21:33
Introduction to Toxicology. is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ?.?.978-1-4471-7256-7978-1-4471-5553-9作者: fetter 時(shí)間: 2025-3-27 01:57
The Emergence of Modern Toxicology, than the thalidomide disaster of the early 1960s. A flurry of activity saw toxicology-focussed societies, journals, regulatory agencies and research institutions established around the world. Toxicology today is a highly evolved, multidisciplinary endeavour that develops its own conceptual framewor作者: Astigmatism 時(shí)間: 2025-3-27 06:11
Toxicokinetics: The Behaviour of Chemicals in the Body,s – in controlling the disposition of ingested chemicals. The possibility that one chemical might alter the ability of these proteins to metabolise or export another xenobiotic is also briefly considered (i.e. toxicant interactions).作者: hazard 時(shí)間: 2025-3-27 12:39 作者: Dealing 時(shí)間: 2025-3-27 16:09 作者: 蠟燭 時(shí)間: 2025-3-27 21:31 作者: BORE 時(shí)間: 2025-3-27 22:57 作者: 明確 時(shí)間: 2025-3-28 02:24
Everyday Toxicology II: Tobacco,NNN and NNK undergo CYP-catalysed bioactivation to DNA-damaging metabolites. DNA adducts formed by these and other noxious metabolites drive the accumulation of mutations in growth regulatory genes within the smokers’ lung.作者: BROTH 時(shí)間: 2025-3-28 08:09
The Emergence of Modern Toxicology,sed toxic plants and metals for therapeutic purposes as well as ‘professional poisoners’ who offered their services to political leaders for the elimination of unwanted rivals. Eventually, the emergence of modern chemistry began unleashing the economic and scientific powers of chemical substances, a作者: Euphonious 時(shí)間: 2025-3-28 11:12
Core Concepts in Toxicology,eeded for the types of substances that are of concern to toxicologists, this chapter explores linguistic nuances surrounding such words as poison, toxin, xenobiotic, endobiotic and toxicant. Next, the complications that can accompany study of toxicity due to differences in the duration of chemical e作者: 廣告 時(shí)間: 2025-3-28 15:05
Toxicokinetics: The Behaviour of Chemicals in the Body, processes dictate the ‘toxicokinetic fate’ of a xenobiotic – describing how it penetrates cell barriers to enter tissues (i.e. absorption), whether it is dispersed to particular organs and tissue compartments (distribution), how it undergoes chemical transformation within the liver (metabolism) and作者: 在駕駛 時(shí)間: 2025-3-28 20:06 作者: 發(fā)怨言 時(shí)間: 2025-3-28 23:04
Fight Back: Adaptive Responses to Toxicant Exposure,perienced a dramatic loss of effectiveness, with higher and higher doses required to elicit the original drug response. This capacity for physical tolerance alerted researchers to the phenomenon of enzyme induction: upon sustained exposure, the liver and other tissues simultaneously boost the expres作者: Condyle 時(shí)間: 2025-3-29 05:09
Target-Organ Toxicity: Liver and Kidney,-inflammatory drugs such as ibuprofen causes kidney damage in vulnerable patients (e.g. the elderly). In addition to these medicinal risks, liver and kidney damages accompany exposure to synthetic chemicals in the workplace or as environmental pollutants. Still other chemicals that harm the excretor作者: 生氣的邊緣 時(shí)間: 2025-3-29 10:53 作者: 文藝 時(shí)間: 2025-3-29 13:17
Chemicals and Cancer,ses possessing unstable genomes and aggressive tendencies to invade local tissue or metastasise to remote sites. Since the accumulation of mutations in critical genes typically underpins these harmful capabilities, modern toxicology devotes much effort to identifying chemicals that cause mutations. 作者: 舊石器時(shí)代 時(shí)間: 2025-3-29 15:35 作者: archaeology 時(shí)間: 2025-3-29 20:39
