標(biāo)題: Titlebook: An Introduction to Bioanalysis of Biopharmaceuticals; Seema Kumar Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusi [打印本頁(yè)] 作者: ETHOS 時(shí)間: 2025-3-21 16:21
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書(shū)目名稱An Introduction to Bioanalysis of Biopharmaceuticals讀者反饋
書(shū)目名稱An Introduction to Bioanalysis of Biopharmaceuticals讀者反饋學(xué)科排名
作者: 安慰 時(shí)間: 2025-3-21 22:11
https://doi.org/10.1007/978-3-663-02224-4tion of these biotherapeutics in biological matrix is mandatory for their pharmacokinetic and pharmacodynamic assessments. Bioanalytical assays thus play an integral role in determining safety and efficacy of therapeutic monoclonal antibodies. Both immunoassays and liquid chromatography with tandem 作者: Handedness 時(shí)間: 2025-3-22 01:37
Die Hungerkatastrophe im Jahre 1921,ly comprises of a cytotoxic small-molecule drug covalently bound to a monoclonal antibody via a linker. Because of their complex structure combining large- and small-molecule drug?characteristics?and their?heterogeneous and dynamic nature, unique bioanalytical strategies are needed to identify, char作者: Magisterial 時(shí)間: 2025-3-22 07:49
https://doi.org/10.1007/978-3-658-12031-3erapeutic modalities are structurally complex and require unique approaches to bioanalysis. For their pharmacokinetic analysis, multiple assays may be required to characterize the disposition of the whole drug molecule as well as the individual?functional domains. The immunogenicity analysis of thes作者: 概觀 時(shí)間: 2025-3-22 10:42 作者: avarice 時(shí)間: 2025-3-22 15:25 作者: 全神貫注于 時(shí)間: 2025-3-22 20:01 作者: Eclampsia 時(shí)間: 2025-3-22 22:24 作者: 包租車船 時(shí)間: 2025-3-23 01:40 作者: panorama 時(shí)間: 2025-3-23 08:07
978-3-030-99998-8The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: Facet-Joints 時(shí)間: 2025-3-23 13:12
An Introduction to Bioanalysis of Biopharmaceuticals978-3-030-97193-9Series ISSN 2210-7371 Series E-ISSN 2210-738X 作者: 不整齊 時(shí)間: 2025-3-23 17:15
Introduction,(LC-MS) have been the work?horse for large-molecule and small-molecule therapeutics, respectively. However, the expansion of therapeutic modalities beyond the conventional realms of large-molecule and small-molecule therapeutics has led to the increased utility of combination of LBA and LC-MS approa作者: leniency 時(shí)間: 2025-3-23 20:06
Gene Therapy and Cell Therapy: Bioanalytical Challenges and Practical Solutions,ays (LBA) and liquid chromatography coupled mass spectrometry?(LC-MS) platforms. Likewise, the bioanalytical strategy for chimeric antigen receptor (CAR) protein on CAR-T-cells also demands unique analytical?platforms such as polymerase chain reaction (PCR). The regulatory expectations on bioanalyti作者: Vulvodynia 時(shí)間: 2025-3-24 01:42 作者: 連接 時(shí)間: 2025-3-24 05:44 作者: accomplishment 時(shí)間: 2025-3-24 10:03 作者: 準(zhǔn)則 時(shí)間: 2025-3-24 11:14 作者: 心胸開(kāi)闊 時(shí)間: 2025-3-24 18:00
An Introduction to Bioanalysis of Biopharmaceuticals作者: 我悲傷 時(shí)間: 2025-3-24 20:31 作者: Aerophagia 時(shí)間: 2025-3-25 00:23
https://doi.org/10.1007/978-3-658-12031-3dditional considerations?due to the complexity of their?structure, additional domain-specific critical reagent generation, and increased assay complexities?due to interferences observed by?individual?functional domains.作者: Anemia 時(shí)間: 2025-3-25 05:56
An Introduction to Bioanalysis of Monoclonal Antibodies,uctory overview of the therapeutic?monoclonal antibodies, bioanalytical assays used for their pharmacokinetics and immunogenicity assessments, and regulatory considerations for the bioanalytical?assays.作者: FLIC 時(shí)間: 2025-3-25 10:41 作者: Gleason-score 時(shí)間: 2025-3-25 12:47
Die Hungerkatastrophe im Jahre 1921,bioanalysis, respectively. This chapter provides an introductory understanding of the structure and chemistry of ADC molecules and various bioanalytical strategies used for their pharmacokinetic and immunogenicity assessment.作者: Onerous 時(shí)間: 2025-3-25 18:55 作者: Innocence 時(shí)間: 2025-3-25 20:56 作者: oncologist 時(shí)間: 2025-3-26 01:22 作者: 死亡率 時(shí)間: 2025-3-26 04:25
Peptides and Oligonucleotide-Based Therapy: Bioanalytical Challenges and Practical Solutions,cations require thorough understanding of these molecules and exclusive strategies to quantify these molecules in various biological matrices. This chapter provides?an overview of currently available?methodologies and strategies?employed?for bioanalytical and immunogenicity assessment of ?peptides and ON therapeutic modalities.作者: 有斑點(diǎn) 時(shí)間: 2025-3-26 12:28
2210-7371 ogether both the diversity of biopharmaceuticals as well as .The book provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness.作者: 浮夸 時(shí)間: 2025-3-26 16:32
Introduction,ust, sensitive, specific, and selective bioanalytical assays that accurately quantitate the analyte(s) of interest. The bioanalysis of large-molecule biotherapeutics is more complex than their lower?molecular?weight counterparts. The immunogenicity of large-molecule biotherapeutics brings another le作者: Merited 時(shí)間: 2025-3-26 18:50 作者: Deduct 時(shí)間: 2025-3-26 22:52
An Introduction to Bioanalysis of Antibody-Drug Conjugates,ly comprises of a cytotoxic small-molecule drug covalently bound to a monoclonal antibody via a linker. Because of their complex structure combining large- and small-molecule drug?characteristics?and their?heterogeneous and dynamic nature, unique bioanalytical strategies are needed to identify, char作者: inhumane 時(shí)間: 2025-3-27 02:42
An Introduction to Bioanalysis of Bispecific and Fusion Proteins,erapeutic modalities are structurally complex and require unique approaches to bioanalysis. For their pharmacokinetic analysis, multiple assays may be required to characterize the disposition of the whole drug molecule as well as the individual?functional domains. The immunogenicity analysis of thes作者: Overthrow 時(shí)間: 2025-3-27 05:46
Gene Therapy and Cell Therapy: Bioanalytical Challenges and Practical Solutions,ssments. The challenges associated with immunogenicity assessment are attributed to the unique delivery systems and complex nature of the immune responses against these multicomponent drug?modalities. Many challenges for the immunogenicity?assays are largely rooted in the critical?reagents and analy作者: 身體萌芽 時(shí)間: 2025-3-27 10:30
Peptides and Oligonucleotide-Based Therapy: Bioanalytical Challenges and Practical Solutions,ders for various disease areas. Peptides and ON molecules are considered as small-molecule drugs?that are synthesized with various chemical and structural modifications to improve?their physicochemical and biological?properties, such as efficacy, stability, bioavailability, safety, etc. These modifi作者: Ptosis 時(shí)間: 2025-3-27 14:31
Production of Transgenic Animals: Practical Problems and Welfare Aspects,cally defined (specified pathogen free, SPF). Active environmental control, health management, and medical surveillance of personnel must be performed on a constant basis..Newly generated animal models should be observed following simple but essential criteria. These observations should also be quan作者: ENDOW 時(shí)間: 2025-3-27 17:56
Applied Computing and Information Technologyons under which the environment gives reward; and (2) we can control the initial state of the environment at the beginning of a training episode. Our method, called ., presents the different episode starting states to an agent in order of increasing distance to immediate reward.作者: Aggressive 時(shí)間: 2025-3-27 22:39 作者: exophthalmos 時(shí)間: 2025-3-28 02:53
,CPM’s 20th Anniversary: A Statistical Retrospective,ablished itself as the most recognized international forum for research in combinatorial pattern matching and related applications. Contributions to the conference typically address issues of searching and matching strings and more complex patterns such as trees, regular expressions, graphs, point s
