標題: Titlebook: Alterations in the Neuronal Cytoskeleton in Alzheimer Disease; George Perry Book 1987 Plenum Press, New York 1987 Alzheimer.Parkinson.bioc [打印本頁] 作者: satisficer 時間: 2025-3-21 20:00
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease影響因子(影響力)
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease影響因子(影響力)學科排名
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease網絡公開度
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease網絡公開度學科排名
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease被引頻次
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease被引頻次學科排名
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease年度引用
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease年度引用學科排名
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease讀者反饋
書目名稱Alterations in the Neuronal Cytoskeleton in Alzheimer Disease讀者反饋學科排名
作者: Expiration 時間: 2025-3-21 22:20
Alterations in the Neuronal Cytoskeleton in Alzheimer Disease作者: Dysplasia 時間: 2025-3-22 02:45 作者: explicit 時間: 2025-3-22 06:57
https://doi.org/10.1007/978-3-662-62692-4re one of the major constituents of neuronal cytoskeletons and play important roles in regulating cell morphology, intracellular transport processes and secretions. The microtubules are polymers of tubulin and they also contain accessory proteins, notably MAP1, MAP2, and the tau proteins..作者: 構成 時間: 2025-3-22 11:41
https://doi.org/10.1007/978-3-642-59907-1in in primary amyloidosis has been shown to be the amino terminal fragment of immunoglobulin light chains with a variable molecular weight, ranging from 5–23 kDa.. Some subgroups of light chains appear to have a highly amyloidogenic primary structure, as shown by preferential association of λVI with作者: 持久 時間: 2025-3-22 13:47 作者: 顛簸下上 時間: 2025-3-22 21:03 作者: Ingredient 時間: 2025-3-23 00:56 作者: 漂亮 時間: 2025-3-23 03:53
Diagnosekodierung in der Praxisapplication of electron microscopy using shadowing and negative staining techniques has revealed the PHF as a left-handed double helix . with a relatively short axial length; this makes the structure different from the fibrous sub-structure of neurofilaments .. Negative staining of isolated PHF, bov作者: 刪除 時間: 2025-3-23 07:51 作者: 爭論 時間: 2025-3-23 13:36
W. Mombour,G. Kockott,R. Degkwitz to diversify microtubules. The association of various MAPs with neuronal microtubules adds to the complexity of this population of cytoskeletal elements. Although microtubules are heterogeneous, they are distributed throughout the neuron. The interaction with MAPs, which are apparently not equally 作者: 收養(yǎng) 時間: 2025-3-23 15:48
The Phosphorylation of the Microtubule-Associated Tau Proteins,re one of the major constituents of neuronal cytoskeletons and play important roles in regulating cell morphology, intracellular transport processes and secretions. The microtubules are polymers of tubulin and they also contain accessory proteins, notably MAP1, MAP2, and the tau proteins..作者: 竊喜 時間: 2025-3-23 18:49 作者: 合適 時間: 2025-3-24 01:55 作者: visual-cortex 時間: 2025-3-24 03:50
,Intraneuronal and Extracellular Filaments in the Pathogenesis of Alzheimer’s Disease, hippocampus, amygdala, cerebral cortex and certain deep gray nuclear structures. Numerous electron microscopic studies have concluded that the vast majority of fibers in these tangles have the appearance of tightly adherent pairs of helically wound, intermediate-sized (10 nm) filaments, referred to作者: 難理解 時間: 2025-3-24 08:50 作者: 專橫 時間: 2025-3-24 11:23 作者: GRIN 時間: 2025-3-24 15:25 作者: acrimony 時間: 2025-3-24 21:21 作者: Externalize 時間: 2025-3-25 01:42 作者: Altitude 時間: 2025-3-25 06:05
Alterations in the Neuronal Cytoskeleton in Alzheimer Disease978-1-4613-1657-2Series ISSN 0099-6246 作者: 字謎游戲 時間: 2025-3-25 10:28 作者: debase 時間: 2025-3-25 13:09 作者: 命令變成大炮 時間: 2025-3-25 18:56
Edgar Hinkelthein,Christoff Zalpour various silver stains. These structures were aptly referred to as “neurofibrils.” It was only relatively recently through combined efforts utilizing electron microscopic, biochemical, and immunological methodologies that these well-known structures have been more precisely defined and characterized作者: 變化 時間: 2025-3-25 23:33
https://doi.org/10.1007/978-3-662-62692-4ttle was known about the molecular mechanims that underlie these responses. There is now considerable evidence indicating that protein phosphorylation plays an important role in neuronal responses to extracellular messengers (for review see .). Protein phosphorylation is involved in a shuttle: i) th作者: 表示問 時間: 2025-3-26 01:01
https://doi.org/10.1007/978-3-642-59907-1e proteins share the properties of a β-pleated sheet secondary structure, insolubility, green birefringence after Congo red staining and the formation of fibrils with a typical electron microscopic appearance.. The deposition of amyloid fibrils is the resultant of a diversity of pathological conditi作者: 專心 時間: 2025-3-26 08:04 作者: 橡子 時間: 2025-3-26 10:40 作者: atopic 時間: 2025-3-26 14:45
https://doi.org/10.1007/978-3-642-60099-9disease (AD). Information was obtained from thin sectioned material using conventional electron microscopy and from thick sections with the high voltage electron microscope. Stereo viewing and computer assisted serial reconstruction techniques were employed to visualize three-dimensional relationshi作者: NEXUS 時間: 2025-3-26 19:23 作者: conifer 時間: 2025-3-26 20:58
https://doi.org/10.1007/978-3-658-01660-9 of the Alzheimer type (Alzheimer’s disease). These two types of lesions are also found in much smaller numbers and in restricted topographical distribution in the brains of many neurologically normal individuals after the seventh decade. Tangles, plaques and other structural changes found in Alzhei作者: 消耗 時間: 2025-3-27 04:42 作者: 含水層 時間: 2025-3-27 06:43
Diagnosekodierung in der PraxisNFT and SP have been found to correlate with the severity of the dementia (1–3). NFT are primarily composed of paired helical filaments (PHF), although 15 nm straight filaments and amorphous components are also common constituents (4). SP, or neuritic plaques, are composed of a core of cerebral amyl作者: 吞沒 時間: 2025-3-27 12:00 作者: Conscientious 時間: 2025-3-27 15:21
W. Mombour,G. Kockott,R. Degkwitzin the pathogenesis of Alzheimer neurofibrillary tangles (ANT).. Some investigators speculate that the mid-molecular weight, heatstable MAP known as tau protein. may be the subunit of the paired helical filament (PHF)., which is the major ultrastructural component of ANT.. Tau is a group of proteins作者: GOAD 時間: 2025-3-27 18:09
W. Mombour,G. Kockott,R. Degkwitzg with other cytoskeletal elements through microtubule-associated proteins (MAPs) (1–4). The formation and maintainance of neuritic processes in vitro is dependent upon the presence of polymerized microtubules (5). By providing an avenue for the vesicular translocator, kinesin, (6) microtubules are 作者: 影響 時間: 2025-3-28 00:51
https://doi.org/10.1007/978-3-642-96254-7change is the Lewy body. Lewy bodies are intraneuronal, cytoplasmic inclusions. They were first described in large neurons of the substantia innominata and dorsal motor nucleus of the vagus (1). We now consider the catecholaminergic nuclei, the substantia nigra and locus ceruleus, to be the typical 作者: 隱語 時間: 2025-3-28 02:31
Hinweise zum Gebrauch des Glossars,and microtubules.. The role of these cytoskeletal components in the neuron has been unclear until recently. These discoveries have implicated the cytoskeleton in many cell functions, including internal organization.. Microfilaments in neurons have mainly been studied in relation to axonal transport.作者: artless 時間: 2025-3-28 09:06
Neurofilaments: A Review and Update, various silver stains. These structures were aptly referred to as “neurofibrils.” It was only relatively recently through combined efforts utilizing electron microscopic, biochemical, and immunological methodologies that these well-known structures have been more precisely defined and characterized作者: 步兵 時間: 2025-3-28 11:27
The Phosphorylation of the Microtubule-Associated Tau Proteins,ttle was known about the molecular mechanims that underlie these responses. There is now considerable evidence indicating that protein phosphorylation plays an important role in neuronal responses to extracellular messengers (for review see .). Protein phosphorylation is involved in a shuttle: i) th作者: Rct393 時間: 2025-3-28 14:48
Human Amyloidosis and In Vitro Formation of Alzheimer Amyloid Fibrils,e proteins share the properties of a β-pleated sheet secondary structure, insolubility, green birefringence after Congo red staining and the formation of fibrils with a typical electron microscopic appearance.. The deposition of amyloid fibrils is the resultant of a diversity of pathological conditi作者: Fallibility 時間: 2025-3-28 20:01
Cloning of Neurofibrillary Tangle-Related Genes,ary tangles (NFT). Electron microscopists were among the first to observe the relative paucity of microtubules in NFT-containing neurons. The microtubular system was later implicated immunochemically, based on an antiserum that cross-reacted with NFT and microtubules.. In 1980 Eng et al.. demonstrat作者: GUEER 時間: 2025-3-29 01:25 作者: 愚笨 時間: 2025-3-29 05:07
,Neuronal Fibrillar Cytoskeleton and Endomembrane System Organization in Alzheimer’s Disease,disease (AD). Information was obtained from thin sectioned material using conventional electron microscopy and from thick sections with the high voltage electron microscope. Stereo viewing and computer assisted serial reconstruction techniques were employed to visualize three-dimensional relationshi作者: 字的誤用 時間: 2025-3-29 11:08
Transformation of the Neurofilamentous Network Components into PHF-Like Strands and PHF Paracrystalological correlation and scientific inquiry. The theory is based on determination of the intensity of tangle formation and plaque counts carried out at the light microscope level, on one hand, and measures of dementia, on the other. Twenty years have passed since this theory was formulated. During t作者: Commonplace 時間: 2025-3-29 14:34
,Intraneuronal and Extracellular Filaments in the Pathogenesis of Alzheimer’s Disease, of the Alzheimer type (Alzheimer’s disease). These two types of lesions are also found in much smaller numbers and in restricted topographical distribution in the brains of many neurologically normal individuals after the seventh decade. Tangles, plaques and other structural changes found in Alzhei作者: 豐滿中國 時間: 2025-3-29 17:56
,Alterations of the Neuronal Cytoskeleton in Alzheimer’s Disease and Related Conditions,the cellular and molecular changes with aging, the mechanism of which remains unknown to date, is the formation of argentophilic intracellular neurofibrillary tangles in certain selected neurons of the aged human brain. These extraordinary neurofibrillary changes are seen in great abundance in sever作者: neutralize 時間: 2025-3-29 22:50
Alteration of the Neurofilament-Microtubule Network in Alzheimer Disease and Other NeurodegenerativNFT and SP have been found to correlate with the severity of the dementia (1–3). NFT are primarily composed of paired helical filaments (PHF), although 15 nm straight filaments and amorphous components are also common constituents (4). SP, or neuritic plaques, are composed of a core of cerebral amyl作者: Analogy 時間: 2025-3-30 02:10
Immunochemical Studies of the Relationship Between the Neuronal Cytoskeleton and Neurofibrillary Tatangles in the cerebral cortex has a diagnostic significance in that the frequency of these structures and the extent of choline acetyltransferase loss is correlated with the degree of dementia .. Tangles are large accumulations of fibrous proteins, the bulk of which has been shown to be composed of作者: esoteric 時間: 2025-3-30 07:37 作者: Climate 時間: 2025-3-30 11:46 作者: meritorious 時間: 2025-3-30 16:22 作者: ALIAS 時間: 2025-3-30 18:00
Microfilament Involvement in Hirano Body Formation,and microtubules.. The role of these cytoskeletal components in the neuron has been unclear until recently. These discoveries have implicated the cytoskeleton in many cell functions, including internal organization.. Microfilaments in neurons have mainly been studied in relation to axonal transport.
