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標(biāo)題: Titlebook: Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo; David Raeburn,Mark A. Giembycz Book 1996 Birkh?user Verlag 1996 Antigen.A [打印本頁(yè)]

作者: ODE    時(shí)間: 2025-3-21 18:15
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作者: 晚間    時(shí)間: 2025-3-21 21:59
Methods of Drug Administration to the Lung in Animals,n the target site is the lung, administration of drugs directly by inhalation provides a rapid onset of action, minimizes systemic exposure and reduces the amount of drug needed to achieve the required therapeutic effect. Thus, in the treatment of human bronchial asthma, bronchodilator, anti-inflamm
作者: 侵蝕    時(shí)間: 2025-3-22 00:34

作者: Emmenagogue    時(shí)間: 2025-3-22 07:15
Antigen-Induced Bronchial Hyperreactivity in Rats,The likelihood of experiencing such an increase in responsiveness appears to be linked to the development of late airway responses (LAR) [1, 2]. A number of animal models of allergic bronchoconstriction have been developed in an effort to understand better the mechanism(s) of these changes [3–6]. Th
作者: Repetitions    時(shí)間: 2025-3-22 11:43
Virus-Induced Bronchial Hyperreactivity,hma exacerbation is most striking in children, in whom at least 30–40% [12–14] and perhaps as many as 75% of exacerbations [15] of asthma are caused by viral infections. The study of the mechanisms of virus-induced asthma attacks has led to the development of animal models.
作者: coddle    時(shí)間: 2025-3-22 16:09

作者: 固定某物    時(shí)間: 2025-3-22 17:38

作者: flamboyant    時(shí)間: 2025-3-22 21:43
Primate Models of Asthma,ion that would be hazardous in humans [1, 2], provide tissue for study ., enable validation of data in a variety of systems, allow genetic and environmental influences to be manipulated or controlled, and facilitate the preclinical assessment of drug efficacy [2].
作者: 窩轉(zhuǎn)脊椎動(dòng)物    時(shí)間: 2025-3-23 03:51

作者: 贊成你    時(shí)間: 2025-3-23 05:40
Transgenic Animals and the Modelling of Asthma,uman experimentation .. Significant genetic, pathophysiological and clinical variation in the presentation and natural history of asthma complicates this experimentation. Obvious economic and ethical concerns also limit the investigation of asthma in human subjects. Nevertheless, direct examination
作者: 固定某物    時(shí)間: 2025-3-23 12:44

作者: 分開(kāi)如此和諧    時(shí)間: 2025-3-23 15:49
Foundation of Quantum Field Theoryion that would be hazardous in humans [1, 2], provide tissue for study ., enable validation of data in a variety of systems, allow genetic and environmental influences to be manipulated or controlled, and facilitate the preclinical assessment of drug efficacy [2].
作者: Axon895    時(shí)間: 2025-3-23 20:24
Res Jost January 10, 1918 – October 3, 1990hial asthma. The increased airway reactivity has been shown to correlate with the severity of the disease, frequency of symptoms and need for treatment [1]. Indeed, these features have been used to define and form the basis of diagnosis of asthma.
作者: 增長(zhǎng)    時(shí)間: 2025-3-24 02:05
https://doi.org/10.1007/978-3-0348-9000-7Antigen; Asthma-Forschung; Glatte Muskulatur der Atemwege; asthma; drug; inflammation; research; smooth mus
作者: Certainty    時(shí)間: 2025-3-24 03:36

作者: Vo2-Max    時(shí)間: 2025-3-24 08:37

作者: Haphazard    時(shí)間: 2025-3-24 14:28
Virus-Induced Bronchial Hyperreactivity,hma exacerbation is most striking in children, in whom at least 30–40% [12–14] and perhaps as many as 75% of exacerbations [15] of asthma are caused by viral infections. The study of the mechanisms of virus-induced asthma attacks has led to the development of animal models.
作者: 夾克怕包裹    時(shí)間: 2025-3-24 15:04
Primate Models of Asthma,ion that would be hazardous in humans [1, 2], provide tissue for study ., enable validation of data in a variety of systems, allow genetic and environmental influences to be manipulated or controlled, and facilitate the preclinical assessment of drug efficacy [2].
作者: photophobia    時(shí)間: 2025-3-24 21:01

作者: 安裝    時(shí)間: 2025-3-25 02:48

作者: Addictive    時(shí)間: 2025-3-25 05:59

作者: AWRY    時(shí)間: 2025-3-25 09:18
Res Jost January 10, 1918 – October 3, 1990delled [1]. Such pathology includes the development of polyphasic reactions [2, 3], the selectively eosinophilic nature of the pulmonary cell infiltrate and the induction of airways hyperresponsiveness following exposure of actively sensitized animals to allergen [4–6]. Moreover, several of these pa
作者: 勛章    時(shí)間: 2025-3-25 12:48

作者: 長(zhǎng)矛    時(shí)間: 2025-3-25 19:13

作者: 我不死扛    時(shí)間: 2025-3-25 21:28
Res Jost January 10, 1918 – October 3, 1990disease characterized by a variety of features including reversible airway obstruction, increased airway responsiveness to various stimuli, and airway inflammation. Various animal models (see accompanying chapters) have been established to mimic and study specific aspects of the human asthmatic resp
作者: Tincture    時(shí)間: 2025-3-26 02:28

作者: ALT    時(shí)間: 2025-3-26 05:16

作者: dandruff    時(shí)間: 2025-3-26 11:24
Res Jost January 10, 1918 – October 3, 1990hial asthma. The increased airway reactivity has been shown to correlate with the severity of the disease, frequency of symptoms and need for treatment [1]. Indeed, these features have been used to define and form the basis of diagnosis of asthma.
作者: 影響深遠(yuǎn)    時(shí)間: 2025-3-26 14:54
https://doi.org/10.1007/978-3-540-49276-4uman experimentation .. Significant genetic, pathophysiological and clinical variation in the presentation and natural history of asthma complicates this experimentation. Obvious economic and ethical concerns also limit the investigation of asthma in human subjects. Nevertheless, direct examination
作者: 使痛苦    時(shí)間: 2025-3-26 17:03

作者: condone    時(shí)間: 2025-3-26 21:13

作者: NOVA    時(shí)間: 2025-3-27 02:55
https://doi.org/10.1007/978-3-540-49276-4 asthma therapy and the inflammatory mechanisms of asthma are now the major focus of research activities in this field. In spite of this insight, the role that individual mediators play in asthmatic inflammation, the fundamental molecular mechanisms leading to the chronicity of asthmatic inflamation
作者: 字的誤用    時(shí)間: 2025-3-27 05:41

作者: 執(zhí)拗    時(shí)間: 2025-3-27 12:13
Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo
作者: 用不完    時(shí)間: 2025-3-27 15:22

作者: acrobat    時(shí)間: 2025-3-27 21:20

作者: Pert敏捷    時(shí)間: 2025-3-27 23:17
n area of particular interest to molecular biologists, is also considered in depth. This up-to-date and extensively referenced work will prove invaluable to pharmacologists, physiologists and other biological scientists at all levels in academia and in the pharmaceutical industry.978-3-0348-9863-8978-3-0348-9000-7
作者: 褲子    時(shí)間: 2025-3-28 04:44
Erinnerungen: Erlesenes und Erlebtesict physical activity and reduce the quality of life. Unfortunately, the prevalence, morbidity and mortality of these lung diseases continue to increase despite the introduction of new medicines and altered treatment guidelines. Consequently research into the regulation of airways smooth muscle . and . has attracted much interest.
作者: 傻    時(shí)間: 2025-3-28 10:04
Res Jost January 10, 1918 – October 3, 1990thological characteristics are modified by established anti-asthma therapies in the guinea pig [6],indication the utility of this species as a relevant animal model for novel drug selection..Author for correspondence.
作者: indenture    時(shí)間: 2025-3-28 14:03

作者: 起來(lái)了    時(shí)間: 2025-3-28 17:54
Das M?rchen vom Elfenbeinernen Turmimmunological studies, forms immunoglobulin E (IgE) on active sensitization [7, 8] and this finding has been recognized as a desirable feature of a model designed for the study of human allergic disease.
作者: 去掉    時(shí)間: 2025-3-28 22:22

作者: overshadow    時(shí)間: 2025-3-29 00:45
Antigen-Induced Bronchial Hyperreactivity in Rats,immunological studies, forms immunoglobulin E (IgE) on active sensitization [7, 8] and this finding has been recognized as a desirable feature of a model designed for the study of human allergic disease.
作者: 針葉    時(shí)間: 2025-3-29 04:35

作者: 啟發(fā)    時(shí)間: 2025-3-29 10:44

作者: NAG    時(shí)間: 2025-3-29 14:14

作者: Truculent    時(shí)間: 2025-3-29 19:29
Methods of Drug Administration to the Lung in Animals,s the amount of drug needed to achieve the required therapeutic effect. Thus, in the treatment of human bronchial asthma, bronchodilator, anti-inflammatory and anti-allergic drugs are generally delivered to the airways as aerosols of respirable size generated either from nebulized solutions or from dispersed dry powders.
作者: arthrodesis    時(shí)間: 2025-3-29 22:26
Book 1996e lung in vivo. The various animal models available for studying the bronchospasm and inflammation associated with human asthma are thoroughly reviewed by internationally recognised scientists. Specific chapters focus on the problems of administering drugs to animal airways, the mechanics of assessi
作者: Texture    時(shí)間: 2025-3-30 00:40

作者: VICT    時(shí)間: 2025-3-30 04:23

作者: metropolitan    時(shí)間: 2025-3-30 10:47
The Rabbit Model of Asthma and the Late Asthmatic Response,onse. This chapter discusses similarities between the allergic rabbit model and the human asthmatic condition and hence the value of the model for the investigation of asthma pathophysiology and the development of novel therapeutic agents.
作者: 主講人    時(shí)間: 2025-3-30 15:27
Peter Reimer,Paul M. Parizel,Falko-A. StichnothIncludes supplementary material:




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