標題: Titlebook: Aging at the Molecular Level; Thomas Zglinicki (Professor of Cellular Gerontolog Book 2003 Springer Science+Business Media Dordrecht 2003 [打印本頁] 作者: Hoover 時間: 2025-3-21 17:09
書目名稱Aging at the Molecular Level影響因子(影響力)
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書目名稱Aging at the Molecular Level被引頻次學科排名
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書目名稱Aging at the Molecular Level讀者反饋學科排名
作者: cornucopia 時間: 2025-3-21 23:31
978-90-481-6482-0Springer Science+Business Media Dordrecht 2003作者: 宇宙你 時間: 2025-3-22 02:02 作者: disrupt 時間: 2025-3-22 06:52 作者: 神秘 時間: 2025-3-22 10:01
Oxidative Damage, Somatic Mutations and Cellular Aging,Many theories have been proposed to explain the aging process. One of the more widely accepted of these is the free radical theory of aging. First presented in 1954, it postulates that aging is caused by the accumulation of damage to the macromolecules of somatic cells by free radicals [1].作者: Indurate 時間: 2025-3-22 15:49
John Connell,Phil McManus,Xuesong Dingolecular damage, and the limited ability of cells, tissues, organs, and individuals to repair it or to maintain function despite it, is the principal driving force of the aging process. A major cause for molecular damage, although by far not the only one (see Chapters 11, 12 and 13, this volume), ar作者: 規(guī)范要多 時間: 2025-3-22 17:15
John Connell,Phil McManus,Xuesong Ding aging in various biological systems. All aerobic organisms are faced with a load of unwanted side reactions caused by the incomplete reduction of oxygen, for example during electron transport and oxidative phosphorylation. Major oxygen radical species are formed such as superoxide and hydroxyl radi作者: 合乎習俗 時間: 2025-3-22 21:35 作者: 假裝是你 時間: 2025-3-23 05:15 作者: 放牧 時間: 2025-3-23 05:49
Chirurgie des Sinus pilonidalis appear much earlier than in the average normal individual; thus, the premature aging disorders are useful models for the study of the aging process (Figure 1). Werner syndrome (WS) is the most characterized premature aging disorder. Patients with WS have a large number of signs and symptoms of norm作者: menopause 時間: 2025-3-23 11:35
Martin E. Kreis,Katharina Beyeres of membrane-bound enzymes (complexes I–IV) and mobile electron carriers (ubiquinone and cytochrome . to molecular oxygen resulting in the formation of water [1]. The chemical energy involved in these electron transfers is stored as a transmembrane chemical gradient established by the translocatio作者: reserve 時間: 2025-3-23 17:42 作者: minion 時間: 2025-3-23 21:07 作者: 大吃大喝 時間: 2025-3-24 00:31 作者: SHRIK 時間: 2025-3-24 04:35 作者: molest 時間: 2025-3-24 07:11
When Historiopraxy Becomes Heritage, pattern of gene expression must be maintained for the normal functioning of cells and for the survival of the organism. Since aging is considered to be a result of failure of maintenance at all levels, attempts have been made to look for an age-related drifting-away of cells in terms of changes in 作者: ICLE 時間: 2025-3-24 12:29
The Native Dimension of Chinese Capitalism, eukaryotes most genes are “silent,” meaning that they are transcriptionally inert and that this state is heritable. Many changes in gene expression occur during cellular senescence and organismal aging [1, 2]. Although most of these are considered to be downstream effects rather than causes of agin作者: 審問 時間: 2025-3-24 17:48 作者: 惰性氣體 時間: 2025-3-24 20:41 作者: bleach 時間: 2025-3-25 00:20 作者: 震驚 時間: 2025-3-25 05:49
Oxidative Damage to Proteins,olites of molecular oxygen known as reactive oxygen species (ROS). The appropriate and inappropriate production of oxidants, together with the ability of organisms to respond to oxidative stress, is intricately connected to aging and life span.作者: ANTI 時間: 2025-3-25 07:36
Mitochondria and Aging,n of protons across the membrane by complexes I,III and IV [2, 3]. This stored energy is then coupled to the formation of ATP by the controlled flow of protons down their chemical gradient within complex V, the ATP synthase.作者: THROB 時間: 2025-3-25 14:37
Metabolic Regulation of Gene Silencing and Life Span,g, there is evidence that gene silencing may be important for determining lifespan. This chapter will provide an introduction to mechanisms of gene silencing and discuss how this (and related mechanisms) may influence longevity. There will be particular focus on how the environment and metabolic activity may regulate gene silencing and lifespan.作者: 粗糙 時間: 2025-3-25 18:39 作者: Concrete 時間: 2025-3-25 22:00
her contributions from an international team of authors, this volume will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutraceutical and health-care industry.978-90-481-6482-0978-94-017-0667-4作者: PANIC 時間: 2025-3-26 01:35 作者: refine 時間: 2025-3-26 07:21 作者: LATHE 時間: 2025-3-26 10:01
Book 2003 field of study and research. The essential cause of aging is molecular damage that slowly overwhelms cellular and organismic defense, repair and maintenance systems. In recent years, a wealth of highly sophisticated research has transformed this idea from a credible hypothesis not only to a major t作者: 未完成 時間: 2025-3-26 15:42 作者: 不公開 時間: 2025-3-26 19:45 作者: 創(chuàng)造性 時間: 2025-3-26 22:39
Contemporary Anthropology of Religionhat can and do influence the structure and function of DNA and proteins, some of which are listed in Table 1. Oxidative events that affect DNA and proteins will be dealt with elsewhere in this volume.作者: BALE 時間: 2025-3-27 01:35 作者: 消息靈通 時間: 2025-3-27 09:20
Probing the , Relevance of Oxidative Stress in Aging Using Knockout and Transgenic Mice, resilient and adaptable: it provides an important mechanistic basis for the rate of living theory, and the two concepts have now essentially merged [2]. Although the oxidative stress theory is currently one of the most popular explanations for how aging occurs at the biochemical level, most of the evidence in its support is correlative.作者: Clumsy 時間: 2025-3-27 12:06 作者: jettison 時間: 2025-3-27 15:39
Christoph Rindfleisch,Bernhard Wichtolites of molecular oxygen known as reactive oxygen species (ROS). The appropriate and inappropriate production of oxidants, together with the ability of organisms to respond to oxidative stress, is intricately connected to aging and life span.作者: 尖牙 時間: 2025-3-27 20:13
Martin E. Kreis,Katharina Beyern of protons across the membrane by complexes I,III and IV [2, 3]. This stored energy is then coupled to the formation of ATP by the controlled flow of protons down their chemical gradient within complex V, the ATP synthase.作者: GRILL 時間: 2025-3-27 23:26
The Native Dimension of Chinese Capitalism,g, there is evidence that gene silencing may be important for determining lifespan. This chapter will provide an introduction to mechanisms of gene silencing and discuss how this (and related mechanisms) may influence longevity. There will be particular focus on how the environment and metabolic activity may regulate gene silencing and lifespan.作者: lymphedema 時間: 2025-3-28 04:05 作者: stress-response 時間: 2025-3-28 06:21 作者: 使成波狀 時間: 2025-3-28 13:02 作者: 輕推 時間: 2025-3-28 17:51
Aging Rate, Mitochondrial Free Radical Production, and Constitutive Sensitivity to Lipid Peroxidati reach 122 years whereas rats only last at best 4 years? Fortunately, some answers to that fundamental question are emerging in recent years. Many different “theories” of aging have been proposed in the past, mainly because gerontological knowledge was seriously limited. The mitochondrial oxygen rad作者: lethargy 時間: 2025-3-28 21:06 作者: 染色體 時間: 2025-3-29 00:29
Mitochondria and Aging,es of membrane-bound enzymes (complexes I–IV) and mobile electron carriers (ubiquinone and cytochrome . to molecular oxygen resulting in the formation of water [1]. The chemical energy involved in these electron transfers is stored as a transmembrane chemical gradient established by the translocatio作者: Fibrillation 時間: 2025-3-29 04:11 作者: adhesive 時間: 2025-3-29 10:37 作者: BROOK 時間: 2025-3-29 12:13 作者: 濃縮 時間: 2025-3-29 18:43
Non-oxidative Modification of DNA and Proteins,potential sources of macromolecular instability both oxidative and non-oxidative. In recent years much attention has been given to the role of reactive oxygen species (ROS) as potential sources macromolecular alteration reflecting the popularity of the free-radical theory of aging. In an attempt to 作者: prostatitis 時間: 2025-3-29 22:38
Transcriptional and Translational Dysregulation During Aging, pattern of gene expression must be maintained for the normal functioning of cells and for the survival of the organism. Since aging is considered to be a result of failure of maintenance at all levels, attempts have been made to look for an age-related drifting-away of cells in terms of changes in 作者: Alcove 時間: 2025-3-30 02:56
Metabolic Regulation of Gene Silencing and Life Span, eukaryotes most genes are “silent,” meaning that they are transcriptionally inert and that this state is heritable. Many changes in gene expression occur during cellular senescence and organismal aging [1, 2]. Although most of these are considered to be downstream effects rather than causes of agin作者: 傲慢物 時間: 2025-3-30 04:13 作者: 制造 時間: 2025-3-30 11:30 作者: 廚師 時間: 2025-3-30 16:01