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標(biāo)題: Titlebook: Aging and Aging-Related Diseases; Mechanisms and Inter Zhao Wang Book 2018 Springer Nature Singapore Pte Ltd. 2018 Aging.Aging-related Dise [打印本頁]

作者: 冠軍    時間: 2025-3-21 18:05
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作者: Fluctuate    時間: 2025-3-21 21:25
Peter J. Fraser,Peter Masakazu TakahataNA molecule. With advances in RNA structure and function analysis, it was found that circRNAs are present in a myriad of life processes and longevity in model organisms such as mice, flies, and worms. Accumulating evidence indicates the involvement of circRNAs in regulation of age-related pathologie
作者: milligram    時間: 2025-3-22 02:23
Peter J. Fraser,Peter Masakazu Takahatamy, society, and individuals. Therefore, identifying therapeutic targets and developing effective strategies to prevent from cardiovascular aging are highly needed. Accumulating evidences suggest that noncoding RNAs (ncRNAs) such as microRNAs and long noncoding RNAs (lncRNAs) play important roles in
作者: LATHE    時間: 2025-3-22 06:04
Catherine H. Gebotys,Simon Ho,C. C. Tiuular cell senescence, vascular dyshomeostasis, and vascular remodeling. Vascular aging is a major risk factor for vascular diseases. However, the current understanding of the biological process of vascular aging and age-related diseases is insufficient. Epigenetic regulation can influence gene expre
作者: LAPSE    時間: 2025-3-22 11:53
https://doi.org/10.1007/978-3-319-30125-9 In human, ApoE has three isoforms, ApoE2, ApoE3, and ApoE4, which are expressed by the polymorphic alleles: ., ., and .. Among the three polymorphic alleles, . is the most risk gene. ApoE is the main ligand for the low-density lipoprotein (LDL) receptor and the LDL receptor-related protein (LRP), f
作者: 無法解釋    時間: 2025-3-22 13:50
Cryptology Transmitted Message Protectionon, age is a major risk factor for most common neurodegenerative diseases, which caused an irreversible cognitive impairment. It has been shown that the function of molecular chaperones, majorly heat shock proteins, was compromised and then causes the imbalance of protein homeostasis inside the cell
作者: 安裝    時間: 2025-3-22 20:07

作者: farewell    時間: 2025-3-22 22:57
https://doi.org/10.1007/978-94-011-1140-9time. With aging, the reconstitution capacity of hematopoietic stem cells decreases accompanying with differentiation skewing wherein the myeloid branch dominates in both mouse and human. In recent years, various molecular mechanisms that induce functional decline of HSC during aging were disclosed
作者: AMITY    時間: 2025-3-23 03:49

作者: Adulate    時間: 2025-3-23 05:46

作者: 光滑    時間: 2025-3-23 13:34

作者: 花束    時間: 2025-3-23 17:19
https://doi.org/10.1007/978-3-030-38065-6ing, significant amounts of the bone are lost due to the loss of this delicate balance toward increased bone resorption coupled with decreased formation, which leads to net bone loss of the aging people. Osteoblasts, osteoclasts, and osteocytes are defined by their respective functions of bone forma
作者: 加入    時間: 2025-3-23 20:06
Conclusion: Comparing Cultural Influences,igh incidence rate of osteoporosis in women was mainly caused by (1) women having fewer skeletons and bone mass, (2) pregnancy consuming a large amount of calcium and other nutrients, and most importantly (3) the cease of estrogen secretion by ovaries after menopause. Along with ovarian aging, the f
作者: negotiable    時間: 2025-3-23 22:34
https://doi.org/10.1007/978-3-319-96782-0tter predict morbidity and mortality, compared to using the chronological age alone.?Most of aging biomarkers were gene, molecules, and protein, which were found in basic scientific researches, such as telomeres, proteomics, cytokines, etc. However, it is?almost impossible for single biomarkers to f
作者: 洞穴    時間: 2025-3-24 04:33

作者: 身體萌芽    時間: 2025-3-24 08:53
Cultural Policy and the Regions,em cell—fertilized egg. After birth, the proliferation and differentiation of stem cells contribute to the development and maturation of individual tissues and organs. After maturation, aging is a phases of the life process, the stem cells within the individual’s tissues ensure the metabolism of dif
作者: Heresy    時間: 2025-3-24 12:43
Gene and Cell Therapy in Heart Failureiseases, and ultimately death. Thus, it has been an ongoing dream of mankind to improve health span and extend the lifespan. In the last century, there is a great increase in the search for eternal youth and an insatiable appetite for methods which could turn back the clock. Survival curves are key
作者: Galactogogue    時間: 2025-3-24 16:03
Aging and Aging-Related Diseases978-981-13-1117-8Series ISSN 0065-2598 Series E-ISSN 2214-8019
作者: 健忘癥    時間: 2025-3-24 19:28

作者: Androgen    時間: 2025-3-24 23:59
978-981-13-4571-5Springer Nature Singapore Pte Ltd. 2018
作者: 馬具    時間: 2025-3-25 05:53
Zhao WangProviding with an overview of recent advances in the study of aging and aging related diseases.Discussing the aging process in different organs and systems.Illustrating the interventions of aging proc
作者: 貧困    時間: 2025-3-25 09:57
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/a/image/151466.jpg
作者: Lignans    時間: 2025-3-25 12:14
Book 2018e, cell, and molecular levels.?It also presents studies on the biomarkers of aging and anti-aging interventions...Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Sinc
作者: CHOKE    時間: 2025-3-25 16:12

作者: finale    時間: 2025-3-25 20:39

作者: Graduated    時間: 2025-3-26 02:58
Brain Aging: Hsp90 and Neurodegenerative Diseases,, which is the most influential reason of brain aging. Here, in this review, we discuss the mechanisms underneath the impairment of heat shock protein function during brain aging, including transcriptional regulation, posttranslational modification, and communication across cells and organs.
作者: lactic    時間: 2025-3-26 07:38
Mechanisms of Hematopoietic Stem Cell Ageing and Targets for Hematopoietic Tumour Prevention,including DNA damage accumulation, metabolic alteration, defects in protein homeostasis, and aging-induced changes in the blood circulatory environment. Deciphering the nature of HSC aging could improve our knowledge of HSC aging-related diseases and furthermore promote the developing of therapeutic interventions for human HSC aging and diseases.
作者: Horizon    時間: 2025-3-26 08:30
Microbiota and Aging, to be researched. In this review, recent research findings are summarized on the role of gut microbiota in aging processes with emphasis on therapeutic potential of microbiome-targeted interventions in antiaging medicine.
作者: 條街道往前推    時間: 2025-3-26 14:21
Aging Kidney and Aging-Related Disease,ental roles in the process of renal aging. To effectively intervene in the process of renal aging, different methods have been tried separately, which could produce different effects. Effective intervention of renal aging could be meaningful for healthy state of the whole body.
作者: 使顯得不重要    時間: 2025-3-26 20:25

作者: excursion    時間: 2025-3-27 00:09
Book 2018e ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field..
作者: Heart-Rate    時間: 2025-3-27 04:02
Barbara S. Beltz,Edward A. Kravitzes, metabolisms, and recently single-cell-level variations. The other is the data analysis methods consisting of network and modeling approaches. With all the data and the tools to analyze them, we could further promote our understanding of the systematic aging.
作者: Discrete    時間: 2025-3-27 08:14

作者: SPECT    時間: 2025-3-27 10:34

作者: assail    時間: 2025-3-27 14:46

作者: Suppository    時間: 2025-3-27 21:03
https://doi.org/10.1007/978-3-030-38065-6ental roles in the process of renal aging. To effectively intervene in the process of renal aging, different methods have been tried separately, which could produce different effects. Effective intervention of renal aging could be meaningful for healthy state of the whole body.
作者: Minikin    時間: 2025-3-28 00:14

作者: 種植,培養(yǎng)    時間: 2025-3-28 04:55
Art: The Economic Point of Viewal of intestinal stem cells can also affect gut aging. Another important aspect that we have discussed is the communication between the gut and the other organ systems which affect the overall aging process. Altogether we propose that the . gut can be a good model to improve our understanding of human gut aging.
作者: vocation    時間: 2025-3-28 06:33

作者: 表示向前    時間: 2025-3-28 13:57

作者: 影響帶來    時間: 2025-3-28 16:00

作者: EXULT    時間: 2025-3-28 18:46
Ovarian Aging and Osteoporosis,he production of cytokines and growth factors from bone marrow and bone cells. This review will summarize current knowledge concerning ovarian aging and postmenopause osteoporosis and also discuss clinical treatment and new ideas of drug development for osteoporosis.
作者: Hyperopia    時間: 2025-3-29 02:11
Pharmaceutical Intervention of Aging,ters, as well as senolytics. All these interventions modulate the determinants and pathways responsible for aging/longevity, such as the kinase target of rapamycin (TOR), AMP-activated protein kinase (AMPK), sirtuins, and insulin-like growth factor (IGF-1) signaling (Fig. 15.1).
作者: 尖牙    時間: 2025-3-29 05:12
Peter J. Fraser,Peter Masakazu Takahata clinical and research fields. In this chapter, we review recent advances in circRNA functions and mechanisms and discuss their roles in aging and age-related diseases. It will provide insight into the regulatory roles of circRNAs in aging and age-related diseases.
作者: 蚊帳    時間: 2025-3-29 08:42
Peter J. Fraser,Peter Masakazu Takahataovascular systems. Here we provided a general overview of ncRNAs as well as the underlying mechanisms involved in cardiovascular aging. Although the importance of ncRNAs in cardiovascular aging has been reported and commonly acknowledged, further studies are still necessary to elucidate the underlying molecular mechanisms.
作者: 加強防衛(wèi)    時間: 2025-3-29 11:56

作者: Frisky    時間: 2025-3-29 16:15

作者: 出生    時間: 2025-3-29 20:59

作者: CONE    時間: 2025-3-30 00:55

作者: 暖昧關(guān)系    時間: 2025-3-30 05:26
Systems Biology in Aging Research,l decline in biological system, the methods in systems biology could be utilized in aging studies. Here we reviewed recent advances in systems biology in aging research and divide them into two major parts. One is the data resource, which includes omics data from DNA, RNA, proteins, epigenetic chang
作者: 搖晃    時間: 2025-3-30 08:21

作者: promote    時間: 2025-3-30 13:07
Noncoding RNAs in Cardiovascular Aging,my, society, and individuals. Therefore, identifying therapeutic targets and developing effective strategies to prevent from cardiovascular aging are highly needed. Accumulating evidences suggest that noncoding RNAs (ncRNAs) such as microRNAs and long noncoding RNAs (lncRNAs) play important roles in
作者: sundowning    時間: 2025-3-30 20:00
Epigenetic Regulation of Vascular Aging and Age-Related Vascular Diseases,ular cell senescence, vascular dyshomeostasis, and vascular remodeling. Vascular aging is a major risk factor for vascular diseases. However, the current understanding of the biological process of vascular aging and age-related diseases is insufficient. Epigenetic regulation can influence gene expre
作者: 吞吞吐吐    時間: 2025-3-30 23:56

作者: Anticonvulsants    時間: 2025-3-31 04:08
Brain Aging: Hsp90 and Neurodegenerative Diseases,on, age is a major risk factor for most common neurodegenerative diseases, which caused an irreversible cognitive impairment. It has been shown that the function of molecular chaperones, majorly heat shock proteins, was compromised and then causes the imbalance of protein homeostasis inside the cell
作者: BANAL    時間: 2025-3-31 05:22
Aging of Human Adult Stem Cells, important approach and main content of regenerative medicine, the stem cell research brings great hope to overcome difficult diseases and improve the quality of life for human beings and become the key to solve this issue. Based on this research, the varying characteristics of stem cells in aging c
作者: nettle    時間: 2025-3-31 12:00

作者: Foreknowledge    時間: 2025-3-31 16:00
Microbiota and Aging,nked to lots of diseases, including human metabolic diseases such as obesity, type 2 diabetes (T2D), irritable bowel syndrome, and cardiovascular disease (CVD). Few studies, however, have noted the relationship between aging and microbiota; the connection between aging and microbiota remains largely
作者: Simulate    時間: 2025-3-31 20:47
Intestinal Homeostasis and Longevity: , Gut Feeling,idences which support the role of gut homeostasis in aging. The . gastrointestinal tract is very similar to the mammalian gut, and therefore it can directly be used as a model to understand the association between gut microbiota, immune system, and aging in humans. In current review we have discusse
作者: Canvas    時間: 2025-4-1 01:44

作者: 公豬    時間: 2025-4-1 01:58

作者: Constitution    時間: 2025-4-1 07:31

作者: mastopexy    時間: 2025-4-1 10:20
Biomarkers of Aging,tter predict morbidity and mortality, compared to using the chronological age alone.?Most of aging biomarkers were gene, molecules, and protein, which were found in basic scientific researches, such as telomeres, proteomics, cytokines, etc. However, it is?almost impossible for single biomarkers to f
作者: Iatrogenic    時間: 2025-4-1 15:08
Pharmaceutical Intervention of Aging,ary risk factor for most age-related diseases, such as cardiovascular diseases, cancers, type 2 diabetes mellitus (T2DM), and neurodegenerative diseases. Pharmacological interventions targeting aging appear to be a more effective approach in preventing age-related disorders compared with the treatme
作者: Working-Memory    時間: 2025-4-1 22:03





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