標(biāo)題: Titlebook: Ageing and Dementia; Current and Future C Kurt A. Jellinger,Reinhold Schmidt,Manfred Windisc Conference proceedings 2002 Springer-Verlag Wi [打印本頁(yè)] 作者: 女孩 時(shí)間: 2025-3-21 18:21
書目名稱Ageing and Dementia影響因子(影響力)
書目名稱Ageing and Dementia影響因子(影響力)學(xué)科排名
書目名稱Ageing and Dementia網(wǎng)絡(luò)公開度
書目名稱Ageing and Dementia網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Ageing and Dementia被引頻次
書目名稱Ageing and Dementia被引頻次學(xué)科排名
書目名稱Ageing and Dementia年度引用
書目名稱Ageing and Dementia年度引用學(xué)科排名
書目名稱Ageing and Dementia讀者反饋
書目名稱Ageing and Dementia讀者反饋學(xué)科排名
作者: helper-T-cells 時(shí)間: 2025-3-22 00:01
Frequency of white matter lesions and silent lacunar infarcts, vary largely among studies. Differences in imaging techniques, ratingscales, cut-off points in lesion severity grading and study populations contribute to the variation, in addition to differences in risk factor profiles acrossstudies..In this paper, we will firstly discuss general methodological i作者: 性別 時(shí)間: 2025-3-22 01:43
CT and MRI rating of white matter changes,iation with cognitive impairment was and still is under debate. To assess WMC in a qualitative and/or semiquantitative fashion rating scales have been developed. For MRI most widely used scales are the scales of Manolio, Fazekas, Schmidt, and Scheltens. Most recently a new scale extending earlier su作者: 怎樣才咆哮 時(shí)間: 2025-3-22 07:22 作者: 縱火 時(shí)間: 2025-3-22 11:29
Microangiopathy-related cerebral damage and angiotensinogen gene: from epidemiology to biology,l hypertension and age are the best accepted risk factors for MARCD. Genes involved in blood pressure regulation, like genes encoding the proteins of the renin-angiotensin system (RAS) therefore represents good candidate genes for MARCD. Plasma angiotensinogen level is a major determinant of the RAS作者: 泰然自若 時(shí)間: 2025-3-22 16:12 作者: 裝入膠囊 時(shí)間: 2025-3-22 18:40 作者: Adulterate 時(shí)間: 2025-3-22 21:53 作者: Discrete 時(shí)間: 2025-3-23 04:15 作者: 老人病學(xué) 時(shí)間: 2025-3-23 06:28 作者: 退出可食用 時(shí)間: 2025-3-23 12:57 作者: 可觸知 時(shí)間: 2025-3-23 15:35 作者: 新義 時(shí)間: 2025-3-23 21:04
,Measuring cognition in advanced Alzheimer’s disease for clinical trials,te Examination (MMSE) and the AD Assessment Scale (ADAS). With the exception of clinical rating scales, however, there are only a few objective measures of cognition for tracking progression in advanced AD. Given renewed interest in potential therapies for advanced AD, objective measures of cognitio作者: CRP743 時(shí)間: 2025-3-24 01:49
,Current drugs and future hopes in the treatment of Alzheimer’s disease,disease progression remains still unclear. New cholinesterase inhibitors should provide an additional neuroprotective activity, because only substances which stop neuronal death can influence disease progression. New treatment strategies are focusing on amyloid processing, preventing the occurrence 作者: 有機(jī)體 時(shí)間: 2025-3-24 04:55
Development of human antibody fragments directed towards synaptic acetylcholinesterase using a semiticholinesterases promote alternative splicing changing the composition of brain AChE variants. To study this phenomenon we developed monoclonal antibodies to acetylcholinesterase synaptic peptide (ASP), a synthetic peptide with the C-terminal sequence unique to the human synaptic variant AChE-S. Sc作者: dictator 時(shí)間: 2025-3-24 07:20
,Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer’ disease,ed for the first time in USA and Europe. All three compounds are cholinesterase inhibitors (ChEI). The major therapeutic effect of ChEI on AD patients is to maintain cognitive function at a stable level during a 6 months to one year period of treatment as compared to placebo. Additional drug effects作者: 世俗 時(shí)間: 2025-3-24 11:43 作者: 咒語(yǔ) 時(shí)間: 2025-3-24 16:40
,Nicotinic receptor modulation: Advantages for successful Alzheimer’s disease therapy,rs (nAChRs). In this report, these two effects are shown to be dependent upon each other using a realistic computer model of the cholinergic synaptic cleft. The model is based upon realistic estimates of the anatomy of a neuronal synapse, the kinetic states of pre-and postsynaptic nAChRs, and the ac作者: Apraxia 時(shí)間: 2025-3-24 21:56
0303-6995 nced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer‘s disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorde作者: 捐助 時(shí)間: 2025-3-25 00:38 作者: CHARM 時(shí)間: 2025-3-25 06:50 作者: 背叛者 時(shí)間: 2025-3-25 09:50 作者: OTHER 時(shí)間: 2025-3-25 13:41 作者: PACT 時(shí)間: 2025-3-25 19:47
Conference proceedings 2002nowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer‘s disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the 作者: Essential 時(shí)間: 2025-3-25 21:28
Serious Gaming and Policy Gaming,ssues that may influence reported frequencies of white matter lesions and silent lacunar infarctions, and then review published data. We will focus on the results from population-based studies and only briefly comment on patient series fo stroke and dementia.作者: Hormones 時(shí)間: 2025-3-26 04:01
Rotor with elastically supported bearings,ggestions has been introduced by Wahlund et al. applicable for both CT and MRL This article will review strengths and weak-nesses of these rating scales and will discuss further requirements and future perspectives.作者: 紳士 時(shí)間: 2025-3-26 04:27 作者: cushion 時(shí)間: 2025-3-26 09:59 作者: 身心疲憊 時(shí)間: 2025-3-26 15:19
Critical Storytelling in Uncritical Timesinally into the stage when a clinical diagnosis of AD is firstpossible. The findings question the generality of common MCI concepts andthe commonly held beliefs about cognitive features in late preclinical stage of AD.作者: menopause 時(shí)間: 2025-3-26 17:09
,A broader horizon of Alzheimer pathogenesis: ALZAS — an early serum biomarker?,erived from AD patients. Most specifically, anendogenous antibody was found in patients with confirmed AD, in patientswith depression, and in subjects suggested to have presymptomatic AD,where it was directed against epitopes within the intron encoded amino acidc-terminal sequence.作者: OMIT 時(shí)間: 2025-3-26 23:12 作者: 厭惡 時(shí)間: 2025-3-27 03:05 作者: Encapsulate 時(shí)間: 2025-3-27 05:50 作者: 卜聞 時(shí)間: 2025-3-27 10:36
Allison Cummings,Amanda Glesingn memory . < 0.001) and visuospatial functions . < 0.02) over six-months with a trend for language and praxis. Data from a donepezil trial also highlight the importance of accurate assessment in advanced AD.作者: CARE 時(shí)間: 2025-3-27 13:55 作者: 神化怪物 時(shí)間: 2025-3-27 19:53
Modetheorien und Fashion Studies,liosis. In rabbits, AF267B & AF150(S) decreased CSF Aβ(1–42 & 1–40), while AF102B reduced Aβ(1–40). Finally AF102B decreased CSF Aβ. in AD patients. Taken together, M1 agonists may represent a unique therapy in AD due to their beneficial effects on three major hallmarks of AD — cholinergic hypofunction, Aβ and τ protein hyperphosphorylation.作者: parallelism 時(shí)間: 2025-3-27 22:04 作者: frozen-shoulder 時(shí)間: 2025-3-28 05:10
,The role of biological markers in the early and differential diagnosis of Alzheimer’s disease, Genetic tests for mutations in the amyloid precursor and presenilin genes are applicable in very few cases. Apolipoprotein E genotyping is not useful as a diagnostic test. With respect to the limitations of biological markers clinical expertise will continue to be an essential element of the early and differential diagnosis of AD.作者: 問到了燒瓶 時(shí)間: 2025-3-28 07:46 作者: 細(xì)微的差異 時(shí)間: 2025-3-28 14:19 作者: concubine 時(shí)間: 2025-3-28 18:35 作者: vascular 時(shí)間: 2025-3-28 21:24 作者: Ligament 時(shí)間: 2025-3-29 00:22 作者: anesthesia 時(shí)間: 2025-3-29 06:16 作者: Microaneurysm 時(shí)間: 2025-3-29 09:15 作者: creatine-kinase 時(shí)間: 2025-3-29 14:10 作者: enmesh 時(shí)間: 2025-3-29 16:52 作者: 啞劇 時(shí)間: 2025-3-29 21:36
https://doi.org/10.1007/978-3-7091-4334-6ical predictors of progression of small vessel disease related cerebral abnormalities including white matter changes and lacunes. White matter hyperintensity progression was found in 17.9% of individuals over the 3 year period. New lacunes occurred in 2.2% of subjects. The overall frequency of progr作者: RALES 時(shí)間: 2025-3-30 01:50 作者: tariff 時(shí)間: 2025-3-30 04:44 作者: SLAG 時(shí)間: 2025-3-30 10:56
Arthur E. Martell,Robert M. Smithget. The major challenges now are establishing the source of the reactive oxygen and what oxidative stress tells us about the etiology of Alzheimer disease. These are complex issues since a variety of enzymatic and nonenzymatic processes are involved in reactive oxygen formation and damage to macrom作者: 薄膜 時(shí)間: 2025-3-30 13:25
https://doi.org/10.1007/978-1-4615-6764-6associated with the activation of mitogenic signaling and cell cycle activation. Brain areas affected by neurofibrillary degeneration in Alzheimer’s disease are structures involved in the regulation of “higher brain functions” that become increasingly predominant as the evolutionary process of encep作者: integral 時(shí)間: 2025-3-30 17:05 作者: 寒冷 時(shí)間: 2025-3-30 21:42
Robert M. Smith,Arthur E. Martell the diagnosis dementia. Various opinions exist about the proportion of people who fall in this boundary condition, the rate at which they will progress to a full dementia syndrome, and the nature and extent of cognitive impairment at the time of MCI diagnosis. There are at least four important dime作者: DEMN 時(shí)間: 2025-3-31 02:53
Critical Storytelling in Uncritical Timesment (MCI) has been a goal for recent research, However, avariety of definitions of MCI-like syndromes and the uncertainty about thefinal diagnosis have hampered progress, To overcome these problems, thepresent study will describe cognitive function in two healthy mutation carriersand two matched no作者: exclusice 時(shí)間: 2025-3-31 07:06
Critical Storytelling in Uncritical Times which may cause similar symptoms. Structural imaging can detect atrophic changes which are largely non-specific and provide little diagnostic information in single patients. Increasing atrophy upon repeated measurement is much more specific to AD. Functional imaging can demonstrate regional alterat作者: AORTA 時(shí)間: 2025-3-31 12:44 作者: defenses 時(shí)間: 2025-3-31 16:54
https://doi.org/10.1007/978-94-6351-005-9disease progression remains still unclear. New cholinesterase inhibitors should provide an additional neuroprotective activity, because only substances which stop neuronal death can influence disease progression. New treatment strategies are focusing on amyloid processing, preventing the occurrence 作者: arboretum 時(shí)間: 2025-3-31 18:10
Pagan Religion in the 21st Centuryticholinesterases promote alternative splicing changing the composition of brain AChE variants. To study this phenomenon we developed monoclonal antibodies to acetylcholinesterase synaptic peptide (ASP), a synthetic peptide with the C-terminal sequence unique to the human synaptic variant AChE-S. Sc作者: 有效 時(shí)間: 2025-3-31 22:29 作者: 網(wǎng)絡(luò)添麻煩 時(shí)間: 2025-4-1 03:12
