標題: Titlebook: Advances in Vision Research, Volume IV; From Basic to Transl Gyan Prakash,Takeshi Iwata Book 2024 This is a U.S. government work and not un [打印本頁] 作者: 徽章 時間: 2025-3-21 18:37
書目名稱Advances in Vision Research, Volume IV影響因子(影響力)
書目名稱Advances in Vision Research, Volume IV影響因子(影響力)學科排名
書目名稱Advances in Vision Research, Volume IV網(wǎng)絡公開度
書目名稱Advances in Vision Research, Volume IV網(wǎng)絡公開度學科排名
書目名稱Advances in Vision Research, Volume IV被引頻次
書目名稱Advances in Vision Research, Volume IV被引頻次學科排名
書目名稱Advances in Vision Research, Volume IV年度引用
書目名稱Advances in Vision Research, Volume IV年度引用學科排名
書目名稱Advances in Vision Research, Volume IV讀者反饋
書目名稱Advances in Vision Research, Volume IV讀者反饋學科排名
作者: 沒有準備 時間: 2025-3-21 23:50 作者: ODIUM 時間: 2025-3-22 03:35 作者: conscribe 時間: 2025-3-22 05:54
Custom Ampliseq Targeted Sequencing Panel for Orphan Pediatric Retinal Diseases,testing is not supported by health insurance, and potentially to benefit the adoption of more economical genetic testing in less developed economies, we developed a custom-targeted panel to sequence these eight genes at a very low cost compared to previous testing methods. Using Illumina Ampliseq pa作者: 籠子 時間: 2025-3-22 09:32
RPE Senescence and Its Implication in Age-Related Macular Degeneration,na is essential for retinal homeostasis by functioning as the outer blood-retinal barrier and transporting nutrients/waste for the retinal photoreceptor cells. It functions as the first line of defense of the retina, and the phenotypic changes in RPE is believed to be the initial trigger for AMD. Th作者: GLUT 時間: 2025-3-22 13:19
Ocular Manifestations of the Oculocerebrorenal Syndrome of Lowe,commended to improve visual stimulation and development. Glaucoma is reported in approximately half of males, which is difficult to control pharmacologically and generally requires surgical intervention. Corrected visual acuity rarely exceeds 20/100, and optical correction with spectacles is recomme作者: Spangle 時間: 2025-3-22 18:23 作者: Biomarker 時間: 2025-3-23 00:05 作者: 心痛 時間: 2025-3-23 02:19
New Insights into AMD Pathogenesis,age experienced during the early disease stages. Understanding the role of altered lipid metabolism in photoreceptors may provide new avenues for the treatment and prevention of age-related macular degeneration.作者: 鞭子 時間: 2025-3-23 05:59 作者: stratum-corneum 時間: 2025-3-23 13:27
Global Prakash: Envisioning a Multi-national Collaboration to Advance Science and Service in Vision In addition to immediately benefiting children by providing them existing treatments, the scientific research undertaken in the network will, in the longer term, help provide a deeper understanding of brain development and its disorders and guidance toward potentially effective novel treatments. In作者: BRUNT 時間: 2025-3-23 15:36
Eye Disease Genetics and Therapeutics,d therapies, and cell therapies will be detailed. Based on the objectives of this book, emphasis will be given to gene-related therapeutics where possible, linking genetic variations within specific genes to disease and potential mitigation and treatment strategies.作者: condemn 時間: 2025-3-23 21:46 作者: Genome 時間: 2025-3-24 00:21
Book 2024ajor resource for all researchers, clinicians, clinical researchers, andallied eye health professionals with an interest in eye diseases around the globe. The first two volumes in the series described the state of the art in genetic eye research in Asia and the Pacific while the third focused on pro作者: charisma 時間: 2025-3-24 05:44
Conrad’s shorter fiction: 1901–1902ic exams and patient history, can aid in identification of numerous IRDs. IRDs can be identified based on whether they affect the rod pathways and evidence abnormalities during dark-adapted ERGs and/or affect the cone pathway and evidence abnormalities during light-adapted ERGs. Abnormalities in the作者: mechanical 時間: 2025-3-24 08:51 作者: 橫條 時間: 2025-3-24 13:10
Marlow’s Initial Response to Jimtesting is not supported by health insurance, and potentially to benefit the adoption of more economical genetic testing in less developed economies, we developed a custom-targeted panel to sequence these eight genes at a very low cost compared to previous testing methods. Using Illumina Ampliseq pa作者: 里程碑 時間: 2025-3-24 15:11 作者: MENT 時間: 2025-3-24 20:55
The Journey to the Inner Stationcommended to improve visual stimulation and development. Glaucoma is reported in approximately half of males, which is difficult to control pharmacologically and generally requires surgical intervention. Corrected visual acuity rarely exceeds 20/100, and optical correction with spectacles is recomme作者: OREX 時間: 2025-3-25 00:07 作者: 和諧 時間: 2025-3-25 04:28
https://doi.org/10.1057/9780230374003lved in DNA demethylation and increased expression of ., coding for a signature mRNA methyltransferase. Treatments with both oxysterols upregulated histone MT genes, while 7kCHOL incubation yielded a profile of numerous histone demethylase DEGs, including some previously linked with photoreceptor ce作者: synovium 時間: 2025-3-25 09:01
https://doi.org/10.1057/9780230374003age experienced during the early disease stages. Understanding the role of altered lipid metabolism in photoreceptors may provide new avenues for the treatment and prevention of age-related macular degeneration.作者: Pathogen 時間: 2025-3-25 14:25 作者: nitric-oxide 時間: 2025-3-25 18:57
https://doi.org/10.1057/9781137559173 In addition to immediately benefiting children by providing them existing treatments, the scientific research undertaken in the network will, in the longer term, help provide a deeper understanding of brain development and its disorders and guidance toward potentially effective novel treatments. In作者: Harness 時間: 2025-3-25 20:49
https://doi.org/10.1057/9781137264671d therapies, and cell therapies will be detailed. Based on the objectives of this book, emphasis will be given to gene-related therapeutics where possible, linking genetic variations within specific genes to disease and potential mitigation and treatment strategies.作者: incubus 時間: 2025-3-26 01:49
https://doi.org/10.1007/978-94-015-9745-6s are a heterogeneous neuronal population; understanding how diseases and treatments affect different RGC types and how this translates between species is vital to therapeutic design. Advances in gene therapy and clustered regularly interspaced short-palindromic repeats (CRISPR)-mediated gene editin作者: 譏諷 時間: 2025-3-26 08:05 作者: connoisseur 時間: 2025-3-26 09:25 作者: minimal 時間: 2025-3-26 15:34
Gene Therapy Trial on X-Linked Retinitis Pigmentosa Caused by Mutations in ,tions, and pathophysiology of .-related RP. In addition, we discuss the development of RPGR gene therapy, from bench to bedside and review the initial results from a gene therapy clinical trial using a full-length codon optimised RPGR vector demonstrating safety and reversal of visual loss in treated patients.作者: apropos 時間: 2025-3-26 20:36 作者: 積習已深 時間: 2025-3-26 23:22 作者: 羽毛長成 時間: 2025-3-27 01:20 作者: 錯事 時間: 2025-3-27 06:59 作者: olfction 時間: 2025-3-27 10:02 作者: 令人不快 時間: 2025-3-27 15:50 作者: 揉雜 時間: 2025-3-27 20:40 作者: 橫截,橫斷 時間: 2025-3-28 01:19
Establishment of the Clinical Genome Resource (ClinGen) X-Linked Inherited Retinal Disease Variant urated variants of these X-linked IRD genes will be used as the standard for molecular diagnosis of patient variants. In this chapter, we describe the purpose of this ClinGen VCEP and outline strategies of establishing the curation rules.作者: phytochemicals 時間: 2025-3-28 04:54
Multifunctional Proteins and Alternative Translation: Functional Diversification of BetaA3/A1-Crystrms are functionally different, and that their functions are also cell- and context-dependent. In this chapter, we review the most recent findings on the evolution and functional diversity of βA3/A1-crystallin and discuss the significance of this multifunctional protein for ocular translational research.作者: APEX 時間: 2025-3-28 08:34
Perceptive Fields and the Study of Inherited Retinal Degeneration,‘receptive fields’, a cellular measure. The existing link between these two measures offers a unique approach to understand the pathological changes associated with inherited retinal dystrophies and helps the design of new therapeutic approaches.作者: 倔強不能 時間: 2025-3-28 12:43 作者: evaculate 時間: 2025-3-28 17:14
1612-3212 tificial retina/cornea.Describes application of AI in transl.This fourth volume in the series .Advances in Vision Research. describes importance advancements in?basics to?translational research, including new therapeutics for genetic eye diseases. Recent US FDA approval of the first gene therapy for作者: 現(xiàn)存 時間: 2025-3-28 19:15 作者: 表示向下 時間: 2025-3-29 02:14 作者: 單調(diào)女 時間: 2025-3-29 06:10
Establishment of the Clinical Genome Resource (ClinGen) X-Linked Inherited Retinal Disease Variant c heterogeneity of IRD, targeted gene therapy is emerging as the main effective approach for treating the disease with many clinical trials currently underway. To maximize the benefit of these emerging therapies to patients, molecular diagnosis is the first critical step. In coordination with the Cl作者: hypnotic 時間: 2025-3-29 08:40
Genotype and Phenotype Characteristics of Major Genes Causing Inherited Retinal Diseases in Difference of IRD in Israel is estimated between 1:1000 and 1:2000 individuals. IRDs are divided into subgroups according to the mutated genes causing the disorder and/or according to the main cell type, which is damaged and does not function properly, i.e., rod-cone dystrophies, the most common example in作者: 2否定 時間: 2025-3-29 13:52
Ocular Genetics and Genetic Eye Research in the Philippines,ng with a lack of healthcare professionals. Due to these compounding factors, emphasis in healthcare has been directed to the leading causes of morbidity and mortality, which are infectious, cardiovascular, and pulmonary diseases. Genetics, which is widely viewed as new and costly, has been given li作者: 留戀 時間: 2025-3-29 17:35
Custom Ampliseq Targeted Sequencing Panel for Orphan Pediatric Retinal Diseases, that impact the retinal vasculature and retinal layer adhesion are very rare. Familial Exudative Vitreo-Retinopathy (FEVR), Norrie Disease (ND), and Persistent Fetal Vascular Syndrome (PFVS) are caused by variants in several genes required for the normal function of retinal vascular endothelial cel作者: chalice 時間: 2025-3-29 23:39
RPE Senescence and Its Implication in Age-Related Macular Degeneration,d persistent DNA damage response, and is associated with metabolic reprogramming, chromatin rearrangement, and autophagy modulation. Senescent cells produce and secrete a combination of factors to exert non-cell-autonomous effects, referred to as senescence-associated secretory phenotype (SASP). Acc作者: seduce 時間: 2025-3-30 00:17 作者: bisphosphonate 時間: 2025-3-30 07:00 作者: 騷擾 時間: 2025-3-30 09:38
Multifunctional Proteins and Alternative Translation: Functional Diversification of BetaA3/A1-Crystnal astrocytes, and ganglion cells. Its function is very context- and cell-specific, ranging from maintaining the structural integrity of the lens to mediating lysosomal clearance and phosphoinositide metabolism in the RPE. In addition to being a classical moonlighting protein (when one polypeptide 作者: 撫育 時間: 2025-3-30 14:45 作者: 可卡 時間: 2025-3-30 17:24
Transcriptomic Analysis of Genes Associated with Nucleic Acid and Histone Methylation and One-Carboysfunction, of the nervous system, including the retina. One such disease is Smith-Lemli-Opitz syndrome (SLOS). 661W cells (a mouse cone photoreceptor-derived cell line) were incubated with cytotoxic concentrations of either 5,9-endoperoxycholest-7-ene-3β,6α-diol (EPCD) or 7-ketocholesterol (7kCHOL)作者: Focus-Words 時間: 2025-3-30 23:04
New Insights into AMD Pathogenesis,ough many risk factors have been identified. Most research efforts are focused on the retinal-pigmented epithelium due to its role in both advanced disease stages, geographic atrophy, and choroidal neovascularization. Here we discuss the role of photoreceptors in age-related macular degeneration pat作者: 任命 時間: 2025-3-31 03:56 作者: delta-waves 時間: 2025-3-31 08:45 作者: GEM 時間: 2025-3-31 09:57
Eye Disease Genetics and Therapeutics,ene product proteins. Deleterious environmental factors, deficiencies in nutraceuticals, inflammation, and aberrant immune responses also cause or synergize with genetic problems to cause or exacerbate the ill-health of the visual system at the structural and functional levels. Identification of gen作者: Pageant 時間: 2025-3-31 14:47
Gene Therapy for Neovascular Age-Related Macular Degeneration: Rationale, Clinical Trials and Futurnised the management and outcomes of neovascular AMD (nAMD). However, the need for repeated intravitreal injections, in some cases lifelong, and the related complications, frequent visits, elevated drug costs and repeated imaging, have resulted in an unsustainable burden both to patients and healthc作者: 小卷發(fā) 時間: 2025-3-31 19:37 作者: chassis 時間: 2025-3-31 22:37
New Paradigm for Long-Acting Retinal Drug Delivery: An Unoprostone-Release Device for the Treatmento approved therapy for the recovery or suppression of the progression of this disease. In this study, we investigated a device offering sustained transscleral delivery of unoprostone isopropyl, which is a potent neuroprotective agent through big potassium channel regulation. The sustained unoproston作者: overhaul 時間: 2025-4-1 03:05 作者: triptans 時間: 2025-4-1 06:49
Gyan Prakash,Takeshi IwataDescribes basic research of potential therapeutic importance.Covers new drug therapy, gene therapy, cell therapy, tissue replacement, and artificial retina/cornea.Describes application of AI in transl作者: Mucosa 時間: 2025-4-1 10:19 作者: Crater 時間: 2025-4-1 16:52
https://doi.org/10.1007/978-981-99-4436-1Translational research; Genetic eye diseases; Gene therapy; Gene editing; Tissue replacement; Stem cell; A作者: 半身雕像 時間: 2025-4-1 21:33 作者: monochromatic 時間: 2025-4-2 00:25
Advances in Vision Research, Volume IV978-981-99-4436-1Series ISSN 1612-3212 Series E-ISSN 2196-890X 作者: 入伍儀式 時間: 2025-4-2 05:40 作者: GONG 時間: 2025-4-2 08:52
Conrad’s shorter fiction: 1901–1902c heterogeneity of IRD, targeted gene therapy is emerging as the main effective approach for treating the disease with many clinical trials currently underway. To maximize the benefit of these emerging therapies to patients, molecular diagnosis is the first critical step. In coordination with the Cl作者: Antarctic 時間: 2025-4-2 13:32
https://doi.org/10.1007/978-1-349-05274-5nce of IRD in Israel is estimated between 1:1000 and 1:2000 individuals. IRDs are divided into subgroups according to the mutated genes causing the disorder and/or according to the main cell type, which is damaged and does not function properly, i.e., rod-cone dystrophies, the most common example in作者: TIA742 時間: 2025-4-2 17:07
