標(biāo)題: Titlebook: Advances in Research on Neurodegeneration; P. Riederer,D. B. Calne,M. B. H. Youdim Conference proceedings 2000 Springer-Verlag Wien 2000 A [打印本頁(yè)] 作者: 威風(fēng) 時(shí)間: 2025-3-21 18:30
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration影響因子(影響力)
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration被引頻次
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration被引頻次學(xué)科排名
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration年度引用
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration年度引用學(xué)科排名
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration讀者反饋
書(shū)目名稱(chēng)Advances in Research on Neurodegeneration讀者反饋學(xué)科排名
作者: languor 時(shí)間: 2025-3-22 00:09 作者: inquisitive 時(shí)間: 2025-3-22 02:16
Hybrid Arrays for Chemical Sensingegenerative diseases. These including the parkinsonian syndromes, the trinucleotide repeat disorders and the dementia syndromes. The increased brain iron is confined to those brain regions most affected by the degeneration characteristic of the particular disorder and is suggested to stimulate cell 作者: Admonish 時(shí)間: 2025-3-22 07:24 作者: Congestion 時(shí)間: 2025-3-22 09:01 作者: ablate 時(shí)間: 2025-3-22 16:28
Benjamin P. Hay,Vyacheslav S. Bryantsevenesis of PD is supported by the demonstration of the high concordance in twins, increased risk among relatives of PD patients in case control and family studies, and the existence of familial PD and parkinsonism based on single gene defects. Recently, several genes have been mapped and/or identifie作者: 憎惡 時(shí)間: 2025-3-22 17:34
Radislav A. Potyrailo,Vladimir M. Mirskyal dopamine neurodegeneration and its protection with R-apomorphine. Both MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and R-apomorphine (R-APO) induced alterations in specific patterns of gene expression. MPTP altered the expression of 49 different genes involved in oxidative stress (oxidati作者: Monocle 時(shí)間: 2025-3-22 22:14 作者: insolence 時(shí)間: 2025-3-23 03:29 作者: 女歌星 時(shí)間: 2025-3-23 09:14
Caleb Lareau,Divy Kangeyan,Martin J. AryeeMAO)-B inhibitor, rasagiline (N-propargyl-(1R)aminoindan), possessing both cholinesterase (ChE) and MAO-inhibitory activity. In doses of 35-100 μmoles/kg administered orally to rats, it inhibits ChE by 25-40% and antagonises scopolamine-induced impairments in spatial memory. After daily administrati作者: Cougar 時(shí)間: 2025-3-23 12:11
Quality Control of Single-Cell RNA-seq,linol, stereo-selectively induced apoptosis in human neuroblastoma SH-SY5Y cells. In this paper the intracellular mechanism of apoptosis was studied using N-methyl(R)salsolinol, 6-hydroxydopamine and peroxynitrite as inducers of apoptosis. Apoptotic cascade was initiated by opening of mitochondrial 作者: anus928 時(shí)間: 2025-3-23 15:12 作者: labile 時(shí)間: 2025-3-23 21:23
Caleb Lareau,Divy Kangeyan,Martin J. Aryeeng properties. It is metabolized to (-)-desmethyldeprenyl, which seems to be the active principle, and further to (-)-amphetamine and (-)-methamphetamine, which antagonize its rescuing effects. These complications may explain the limited neurorescuing potential of (-)-deprenyl observed clinically.作者: BUCK 時(shí)間: 2025-3-23 23:01 作者: 旋轉(zhuǎn)一周 時(shí)間: 2025-3-24 05:32 作者: 大笑 時(shí)間: 2025-3-24 09:54
Antti Ylinen,Jari M?kinen,Reijo Kouhianervous system. We know that neuronal cell death is regulated by a genetically encoded programme, called apoptosis, that is conserved from worms to humans. Dysregulation of this programme is thought to contribute to neurodegenerative diseases which are characterized by the loss of neurons. This arti作者: 樹(shù)膠 時(shí)間: 2025-3-24 14:32 作者: LATE 時(shí)間: 2025-3-24 16:49 作者: 諂媚于人 時(shí)間: 2025-3-24 21:36
Applied and Numerical Harmonic Analysis in the striatum are responsible for most of the movement disturbances called parkinsonism, observed in Parkinson’s disease (PD). One hypothesis of the cause of degeneration of the nigrostriatal DA neurons is that PD is caused by programmed cell death (apoptosis) due to increased levels of cytokines作者: folliculitis 時(shí)間: 2025-3-25 01:10 作者: Legend 時(shí)間: 2025-3-25 05:38
Advances in Research on Neurodegeneration978-3-7091-6301-6Series ISSN 0303-6995 作者: chassis 時(shí)間: 2025-3-25 11:02
0303-6995 Overview: 978-3-211-83537-1978-3-7091-6301-6Series ISSN 0303-6995 作者: 裁決 時(shí)間: 2025-3-25 14:32 作者: Narrative 時(shí)間: 2025-3-25 17:35 作者: Gerontology 時(shí)間: 2025-3-25 21:51 作者: Observe 時(shí)間: 2025-3-26 03:38 作者: Hamper 時(shí)間: 2025-3-26 05:02 作者: 寬容 時(shí)間: 2025-3-26 10:36
,GDF-15/MIC-1 a novel member of the TGF-? superfamily,. In addition we have preliminary evidence that GDF-15/MIC-1 is a potent trophic factor for selected classes of neurons in vitro and in vivo. Thus, GDF-15 is a novel neurotrophic factor with prospects for the treatment of disorders of the CNS.作者: Incise 時(shí)間: 2025-3-26 13:10 作者: forestry 時(shí)間: 2025-3-26 19:52
Margaret A. Ryan,Abhijit V. Shevade The current major hypothesis suggests that nigral neuronal death in PD is due to excessive oxidative stress generated by auto-and enzymatic oxidation of the endogenous neurotransmitter dopamine (DA), the formation of neuromelanin and presence of high concentrations of iron.作者: –吃 時(shí)間: 2025-3-26 23:52 作者: archenemy 時(shí)間: 2025-3-27 04:17
The molecular mechanism of dopamine-induced apoptosis: identification and characterization of genes The current major hypothesis suggests that nigral neuronal death in PD is due to excessive oxidative stress generated by auto-and enzymatic oxidation of the endogenous neurotransmitter dopamine (DA), the formation of neuromelanin and presence of high concentrations of iron.作者: 道學(xué)氣 時(shí)間: 2025-3-27 05:29
,Monitoring neuroprotection and restorative therapies in Parkinson’s disease with PET, PET findings in transplantation trials involving implantation of human and procine fetal mesencephalic tissue is presented. It is concluded that functional imaging provides a valuable adjunct to clinical assessment when judging the efficacy of neuroprotective and restorative approaches to PD.作者: 噴出 時(shí)間: 2025-3-27 11:17 作者: 舉止粗野的人 時(shí)間: 2025-3-27 15:10
Homocysteine and alcoholism,hermore, it has been found that homocysteine induces neuronal cell damage bytimulating NMDA receptors as well as by producing free radicals. Homocysteine neurotoxicity via overstimulation of N- ethyl-D-aspartate receptors may contribute to the pathogenesis of both brain shrinkage and withdrawal seizures linked to alcoholism.作者: synovium 時(shí)間: 2025-3-27 20:22
Computational Methods in Applied Sciences. In addition we have preliminary evidence that GDF-15/MIC-1 is a potent trophic factor for selected classes of neurons in vitro and in vivo. Thus, GDF-15 is a novel neurotrophic factor with prospects for the treatment of disorders of the CNS.作者: GLUE 時(shí)間: 2025-3-27 22:44
The ,-DOPA story revisited. Further surprises to be expected?,cific neurochemical deficits in defined brain regions were identified, and thus for which a rational, chemical therapy could be developed, ushering in the era of clinical neurochemistry. The contributions of Birkmayer and Hornykiewicz (Vienna), Barbeau and Sourkes (Montreal) and of Cotzias (New York作者: Hearten 時(shí)間: 2025-3-28 03:29 作者: Compass 時(shí)間: 2025-3-28 08:09 作者: AROMA 時(shí)間: 2025-3-28 13:09 作者: Bridle 時(shí)間: 2025-3-28 17:27 作者: 放肆的我 時(shí)間: 2025-3-28 18:51
,Importance of familial Parkinson’s disease and parkinsonism to the understanding of nigral degeneraenesis of PD is supported by the demonstration of the high concordance in twins, increased risk among relatives of PD patients in case control and family studies, and the existence of familial PD and parkinsonism based on single gene defects. Recently, several genes have been mapped and/or identifie作者: 種屬關(guān)系 時(shí)間: 2025-3-28 23:14
cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in Mal dopamine neurodegeneration and its protection with R-apomorphine. Both MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and R-apomorphine (R-APO) induced alterations in specific patterns of gene expression. MPTP altered the expression of 49 different genes involved in oxidative stress (oxidati作者: 聯(lián)合 時(shí)間: 2025-3-29 04:46
,Monitoring neuroprotection and restorative therapies in Parkinson’s disease with PET,ussed. The potential value of PET and SPECT for assessing the efficacy of putative neuroprotective agents in PD is considered and a review of 18F-dopa PET findings in transplantation trials involving implantation of human and procine fetal mesencephalic tissue is presented. It is concluded that func作者: ANIM 時(shí)間: 2025-3-29 10:15 作者: 媽媽不開(kāi)心 時(shí)間: 2025-3-29 13:28
TV3326, a novel neuroprotective drug with cholinesterase and monoamine oxidase inhibitory activitieMAO)-B inhibitor, rasagiline (N-propargyl-(1R)aminoindan), possessing both cholinesterase (ChE) and MAO-inhibitory activity. In doses of 35-100 μmoles/kg administered orally to rats, it inhibits ChE by 25-40% and antagonises scopolamine-induced impairments in spatial memory. After daily administrati作者: 輕而薄 時(shí)間: 2025-3-29 18:05 作者: 過(guò)多 時(shí)間: 2025-3-29 23:40 作者: 匍匐前進(jìn) 時(shí)間: 2025-3-30 00:27
Neurorescuing effects of the GAPDH ligand CGP 3466B,ng properties. It is metabolized to (-)-desmethyldeprenyl, which seems to be the active principle, and further to (-)-amphetamine and (-)-methamphetamine, which antagonize its rescuing effects. These complications may explain the limited neurorescuing potential of (-)-deprenyl observed clinically.作者: Unsaturated-Fat 時(shí)間: 2025-3-30 08:06 作者: 神圣在玷污 時(shí)間: 2025-3-30 11:06
Neurotrophic effects of central nicotinic receptor activation,o, the potential to be neuroprotective and that treatment with nAChR agonists elicit long-lasting improvement of cognitive performance in a variety of behavioural tests in rats, monkeys and humans. Epidemiological and clinical studies suggested also a potential neuroprotective/trophic role of (—)-ni作者: PALSY 時(shí)間: 2025-3-30 15:20
Regulation of neuronal cell death and differentiation by NGF and IAP family members,nervous system. We know that neuronal cell death is regulated by a genetically encoded programme, called apoptosis, that is conserved from worms to humans. Dysregulation of this programme is thought to contribute to neurodegenerative diseases which are characterized by the loss of neurons. This arti作者: 反感 時(shí)間: 2025-3-30 19:30 作者: echnic 時(shí)間: 2025-3-31 00:09 作者: 規(guī)范就好 時(shí)間: 2025-3-31 01:30 作者: dura-mater 時(shí)間: 2025-3-31 05:59
Sebastian Z?llner,Jonathan K. Pritchardrience with L-DOPA, Sano deserves to be remembered as one of the pioneers in catecholamine research, having been the first to map dopamine levels in the human brain, and identified the reduction of dopamine levels in the substantia nigra and striatum in Parkinson’s disease.作者: 飲料 時(shí)間: 2025-3-31 10:17
Lecture Notes in Computer Sciencengles and amyloid deposits, but only 1 in 2.600 to 5.600 neurons displayed apoptotic morphology and cytoplasmic immunoreactivity for activated caspase-3, whereas no neurons were labeled in age-matched controls. caspase-3 immunoreactivity was seen in granules of cells with granulovacuolar degeneratio作者: 細(xì)菌等 時(shí)間: 2025-3-31 14:28
Hybrid Arrays for Chemical Sensingnoma may be a secondary, rather than a primary initiating event, a hypothesis also supported by evidence from animal experiments. The source of the increased iron is unknown but a variety of changes in iron homeostasis have been identified in PD, both in the brain and in the periphery. The possibili作者: 谷類(lèi) 時(shí)間: 2025-3-31 21:18 作者: 系列 時(shí)間: 2025-3-31 23:45
Benjamin P. Hay,Vyacheslav S. Bryantsevdominant form of typical PD, although only a single family has so far been identified with a mutation of this gene, and tau has been identified as a causative gene for frontotemporal dementia and parkinsonism. In addition, five other chromosome loci have been identified to be linked to familial PD o作者: STIT 時(shí)間: 2025-4-1 02:30
Radislav A. Potyrailo,Vladimir M. Mirskyd signal transduction factors), that might act in parallel to oxidative stress (OS) and inflammation, to converge eventually into a common pathway leading to neurodegeneration. R-APO, previously shown by us to protect against MPTP neurotoxicity, prevented the over expression of several genes known t
