標題: Titlebook: Advances in Rapid Sex-Steroid Action; New Challenges and N Gabriella Castoria,Antimo Migliaccio Book 2012 Springer Science+Business Media, [打印本頁] 作者: 黑暗社會 時間: 2025-3-21 19:38
書目名稱Advances in Rapid Sex-Steroid Action影響因子(影響力)
書目名稱Advances in Rapid Sex-Steroid Action影響因子(影響力)學科排名
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書目名稱Advances in Rapid Sex-Steroid Action網(wǎng)絡公開度學科排名
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書目名稱Advances in Rapid Sex-Steroid Action被引頻次學科排名
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書目名稱Advances in Rapid Sex-Steroid Action年度引用學科排名
書目名稱Advances in Rapid Sex-Steroid Action讀者反饋
書目名稱Advances in Rapid Sex-Steroid Action讀者反饋學科排名
作者: lacrimal-gland 時間: 2025-3-21 22:24 作者: Grasping 時間: 2025-3-22 03:00
f significant numbers of master proteins in breast and prostBreast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to horm作者: Immunotherapy 時間: 2025-3-22 04:42
S. G. Ponnambalam,N. Jawahar,B. S. Girish for the treatment of breast cancer, as well as other malignancies. Several small-molecule inhibitors and monoclonal antibodies are currently being tested or used in the clinic for the treatment of these tumors.作者: 兵團 時間: 2025-3-22 11:51 作者: 緯線 時間: 2025-3-22 13:30 作者: maintenance 時間: 2025-3-22 20:02 作者: 逃避現(xiàn)實 時間: 2025-3-22 22:23 作者: 調(diào)整校對 時間: 2025-3-23 01:30
Nongenomic Actions of Estrogens and Xenoestrogens Affecting Endocrine Cancer Cellsreceptors and signaling systems, but do so imperfectly, causing disruptions to both the phasing and dose-responsiveness of physiologic estrogens. Disruptions to the signaling of different physiologic estrogens could cause life stage-specific tissue malfunctions or cancer vulnerabilities.作者: 痛得哭了 時間: 2025-3-23 06:59
Androgen Receptor Pathway in Prostate Cancer: Old Target and New Drugsement. Several novel agents targeting the androgen receptor signaling are currently being evaluated including Abiraterone, MDV-3100, orteronel (TAK-700), and other compounds currently in early development.作者: 背帶 時間: 2025-3-23 10:50 作者: 敵手 時間: 2025-3-23 15:40 作者: 災禍 時間: 2025-3-23 21:49
Betul Yagmahan,Mehmet Mutlu Yeniseyo crosstalk to kinase cascades activated by signals impinging on membrane receptors. Progesterone treatment of cells in culture leads to the rapid activation of several kinases and in particular the Src/Ras/Erk/Msk1 cascade, by activating a small population of membrane-anchored progesterone receptor作者: 支架 時間: 2025-3-24 00:40 作者: jeopardize 時間: 2025-3-24 05:21 作者: 拋棄的貨物 時間: 2025-3-24 06:44 作者: 脆弱吧 時間: 2025-3-24 13:28
Amandeep Kaur,Anuj Kumar Gupta,Harpreet Kaurmerging evidence indicates that the interaction with the extracellular environment and cell movement are regulated by sex steroids through such rapid mechanisms. Exposure of different cell types to estrogen, progesterone or other steroids results in swift changes in the morphology of the cells, prim作者: macular-edema 時間: 2025-3-24 17:21 作者: 赤字 時間: 2025-3-24 20:03 作者: 宣誓書 時間: 2025-3-25 00:00
David Sánchez,David Isern,Antonio Morenoinding to AR has become the major therapeutic option. However, the ADT is initially effective on blocking tumor growth, but eventually fails, leading to a stage of castration resistant prostate cancer and more advanced metastatic stage. The failure might be due to the nonspecific targeting of androg作者: 聯(lián)邦 時間: 2025-3-25 04:18
Explaining Medical Model Exceptions (ADT) represents a good therapeutic tool for the treatment of PCa patients, but after an initial period of remission, the disease progresses towards an androgen-independent (AI) state. While in androgen-dependent (AD) stage the roles of androgens and their receptor (AR) are fully described inAI, th作者: 小平面 時間: 2025-3-25 10:16
Studies in Computational Intelligence-like growth factors (IGF) I and II plays a role in the development and progression of a variety of malignancies, including prostate cancer. Recent studies indicate that membrane-initiated effects of both androgens and estrogens provide a non-mutational mechanism for marked IGF-IR upregulation in pr作者: 最高點 時間: 2025-3-25 11:44
S Spelmen Vimalraj,Porkodi Rajendranan exquisite sensitivity to androgen deprivation therapy and is the most endocrine-sensitive solid neoplasm, although the disease may eventually progress to the castration-resistant status (CRPC). However, recent evidence was provided that the cancer progression at the CRPC stage is often mediated b作者: 行為 時間: 2025-3-25 17:30
https://doi.org/10.1007/978-3-642-30621-1have provided deep insights into NR function but, due to their nature as single endpoint assays derived from pooled cell populations and tissues, these approaches are intrinsically unable to address important mechanistic considerations linked to cellular heterogeneity. Androgen receptor (AR) and est作者: Insatiable 時間: 2025-3-25 22:26
Mattia Broilo,Francesco G. B. De Natalelter gene expression. These processes typically take at least 30 to 60 min for an increase in mRNA expression to be observed. In contrast, other regulatory actions of steroid hormones such as increases in activity of mitogen activated protein kinases are manifested within seconds to a few minutes an作者: 手榴彈 時間: 2025-3-26 04:05 作者: 孵卵器 時間: 2025-3-26 07:06 作者: 細頸瓶 時間: 2025-3-26 09:45
http://image.papertrans.cn/a/image/149543.jpg作者: Middle-Ear 時間: 2025-3-26 13:41
Cosmin Danut Bocaniala,José Sá da Costasic model of steroid hormone action as restricted to classic cell types rather than valid for all steroid target cells. Cross talk between membrane receptors and nuclear steroid receptors regulates nuclear steroid receptor action. An additional cross talk occurring between membrane receptors and ext作者: Fibrinogen 時間: 2025-3-26 16:49 作者: HAIL 時間: 2025-3-26 22:33
N. N. Schraudolph,P. Dayan,T. J. Sejnowskius, the function of ER may not be solely dependent on the steady state levels of ER protein. A subset of ER negative breast cancers that have ER mRNA but lack detectable ER protein levels may ultimately prove to be responsive to estrogen. These observations may have broader implications for estrogen作者: BINGE 時間: 2025-3-27 03:29 作者: 可憎 時間: 2025-3-27 06:12
Explaining Medical Model Exceptionsutic strategies against the development of breast cancer. Furthermore, the promiscuous activity exerted by antiestrogens, which act as GPER agonists and antagonists of the nuclear estrogen receptors, addresses the need of new selective estrogen receptor inhibitors.作者: 殺死 時間: 2025-3-27 13:19
David Sánchez,David Isern,Antonio Morenoen/AR signaling can suppress one type of tumor at a specific stage, but may lead to undesired more aggressive tumors. Accordingly, a combined therapy targeting both tumor stages and different cell types in the tumor microenvironment should be considered. Recently, several promising anti-androgen and作者: 爭吵加 時間: 2025-3-27 15:49 作者: Trochlea 時間: 2025-3-27 17:57
Studies in Computational Intelligences IGF-IR gene transcription. IGF-IR upregulation sensitizes prostate cancer cells to the proliferative and protumor effects of IGFs. As IGF-IR activation by IGFs contributes to CREB activation, this mechanism may be involved in a positive feed-back loop implicated in IGF-IR overexpression in prostat作者: 大包裹 時間: 2025-3-27 21:58
https://doi.org/10.1007/978-3-642-30621-1lar compartments in response to physiologic, pathologic or pharmacologic stimuli, to quantify transcriptional activity, and to identify interacting molecules leading to induction, or repression, of transcription. Here, we discuss recent reports that have applied advanced imaging systems [high throug作者: GIDDY 時間: 2025-3-28 05:42
Mattia Broilo,Francesco G. B. De Nataleptors at the membrane due to their dynamic behaviour, subcellular sizes and complexity of action. Here we describe a novel technique for studying the non-genomic action of steroid hormones making use of dip-pen nanolithography (DPN) for patterning supported lipid bilayers containing haptenated lipid作者: Proponent 時間: 2025-3-28 07:44 作者: Palliation 時間: 2025-3-28 10:28
Non-genomic Action of Steroid Hormones: More Questions than Answers,sic model of steroid hormone action as restricted to classic cell types rather than valid for all steroid target cells. Cross talk between membrane receptors and nuclear steroid receptors regulates nuclear steroid receptor action. An additional cross talk occurring between membrane receptors and ext作者: 外表讀作 時間: 2025-3-28 16:57 作者: 卜聞 時間: 2025-3-28 22:00
Cross Talk Between ERα and Src Signaling and Its Relevance to ER Status and Hormone Responsivenessus, the function of ER may not be solely dependent on the steady state levels of ER protein. A subset of ER negative breast cancers that have ER mRNA but lack detectable ER protein levels may ultimately prove to be responsive to estrogen. These observations may have broader implications for estrogen作者: 無辜 時間: 2025-3-28 23:06
Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancered during exposure to estrogen or other steroids, which indicate that these steroids are powerful regulators of cell movement. Many of these actions are enacted via the rapid activation on extra-nuclear signaling cascades of sex steroid receptors that lead to the recruitment of small GTPases such as作者: Vital-Signs 時間: 2025-3-29 04:01
Unraveling the Role of GPER in Breast Cancerutic strategies against the development of breast cancer. Furthermore, the promiscuous activity exerted by antiestrogens, which act as GPER agonists and antagonists of the nuclear estrogen receptors, addresses the need of new selective estrogen receptor inhibitors.作者: faucet 時間: 2025-3-29 10:07 作者: Circumscribe 時間: 2025-3-29 11:59 作者: reception 時間: 2025-3-29 18:43 作者: defendant 時間: 2025-3-29 19:56 作者: 忍耐 時間: 2025-3-30 02:12
Micropatterned Surfaces as Tools for the Study of the Rapid Non-Genomic Actions of Steroid Receptorsptors at the membrane due to their dynamic behaviour, subcellular sizes and complexity of action. Here we describe a novel technique for studying the non-genomic action of steroid hormones making use of dip-pen nanolithography (DPN) for patterning supported lipid bilayers containing haptenated lipid作者: 混合物 時間: 2025-3-30 06:27
Mechanisms of Signal Transduction in Prostate Cancer: The Role of PI3-Kinase Pathway in Androgen Act作者: Ablation 時間: 2025-3-30 09:04 作者: 駕駛 時間: 2025-3-30 14:40 作者: Communicate 時間: 2025-3-30 20:00 作者: octogenarian 時間: 2025-3-30 23:10 作者: Colonnade 時間: 2025-3-31 03:38 作者: ascend 時間: 2025-3-31 06:12
Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancermerging evidence indicates that the interaction with the extracellular environment and cell movement are regulated by sex steroids through such rapid mechanisms. Exposure of different cell types to estrogen, progesterone or other steroids results in swift changes in the morphology of the cells, prim作者: 分散 時間: 2025-3-31 12:21
Unraveling the Role of GPER in Breast Cancerhich estrogens induce diverse biological responses as well as pathological processes, including cancer development and progression. In this regard, it has been shown that not only estrogens but also antiestrogens binding to and activating the GPER-dependent signaling elicit stimulatory effects in ho
