標(biāo)題: Titlebook: A Multidisciplinary Approach to Myelin Diseases II; S. Salvati Book 1994 Springer Science+Business Media New York 1994 Antigen.biology.bra [打印本頁(yè)] 作者: Adentitious 時(shí)間: 2025-3-21 16:31
書(shū)目名稱(chēng)A Multidisciplinary Approach to Myelin Diseases II影響因子(影響力)
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書(shū)目名稱(chēng)A Multidisciplinary Approach to Myelin Diseases II讀者反饋
書(shū)目名稱(chēng)A Multidisciplinary Approach to Myelin Diseases II讀者反饋學(xué)科排名
作者: 母豬 時(shí)間: 2025-3-21 21:54
https://doi.org/10.1007/978-3-642-79603-6rowth-arrested (Schneider et al., 1988; Manfioletti et al., 1990). The demonstration that gas3 is also a prominent Schwann cell gene product came from the independent cloning of cDNAs that are either induced or repressed following rat sciatic nerve crush or transection (Spreyer et al., 1991; Welcher作者: 無(wú)能的人 時(shí)間: 2025-3-22 02:00 作者: ALIEN 時(shí)間: 2025-3-22 06:52 作者: 整潔漂亮 時(shí)間: 2025-3-22 11:26 作者: 懸崖 時(shí)間: 2025-3-22 14:28
https://doi.org/10.1007/BFb0022001ur sometime between the initial acute inflammatory, actively demyelinating phase when oligodendrocytes are abundant, and the chronic, silent fibrous astrogliotic MS plaque where few, if any, oligodendrocytes can be located.. Complicating the analysis of factors underlying the demise of the oligodend作者: 無(wú)政府主義者 時(shí)間: 2025-3-22 20:26
An Approach to Knowledge Base Managementducing processes between myelin lamellae and actively stripping sheets of membrane from the myelin sheath, which is then phagocytosed by a process resembling receptor mediated endocytosis. Interestingly the phagocytosis of myelin is closely associated with the capping of IgG on the macrophage surfac作者: chuckle 時(shí)間: 2025-3-22 23:14 作者: innate 時(shí)間: 2025-3-23 02:55 作者: 序曲 時(shí)間: 2025-3-23 07:06
Axonal Contact Induces Oligodendroglial Specific Transcription of the , Gene from the Proximal Promoney (Oak Ridge National Laboratory), Dr. Gabriel Favelukes (University of La Plata), Dr. Barbara Ham- kalo (Oak Ridge National Laboratory), and Dr. J. T. August (Albert Einstein College of Medicine). As in previous symposia, excellent support has come from the Ford Founda- tion through a grant to the National978-1-4684-0879-9978-1-4684-0877-5作者: septicemia 時(shí)間: 2025-3-23 12:24
Retrovirus-Mediated Gene Transfer of PMP22 in Schwann Cells: Studies on Cell Growthpolypeptides that are present both in normal and transformed cells and that are common to many cell types analyzed (9). Some of these polypeptides may correspond to . (12–14; see also other articles in this volume), and the elucidation of their function may lead a better understanding of the process作者: 偶然 時(shí)間: 2025-3-23 13:59
Protein Sorting and Targeting in Myelin-Forming Schwann Cellsc material — the breaking and making of internucleotide bonds or the modification of DNA nucleotides — and not the passive use of DNA as a template, as in transcription (Chapter 2). These processes, DNA replication, recombination and repair (mutation has been discussed in Chapter 3), have many gene 作者: 性滿足 時(shí)間: 2025-3-23 19:43 作者: Angioplasty 時(shí)間: 2025-3-24 00:10 作者: 西瓜 時(shí)間: 2025-3-24 03:32
Mechanisms of DE — and Remyelination in Autoimmune Encephalomyelitis and Multiple Sclerosisof these proteins, ovalbumin, has been studied extensively. Ovalbumin mRNA has been purified (Rosen et al. 1975), and a full-length dsDNA copy synthesized (Monahan et al. 1976b) and cloned in a bacterial plasmid (McReynolds et al. 1977). More recently, ovalbumin genomic DNA sequences have been isola作者: dendrites 時(shí)間: 2025-3-24 07:33
The Immunologic Response of the Oligodendrocyte in the Active Multiple Sclerosis Lesionrest in the structure of chromatin beyond the nucleosome-that is, the superstructural characteris- tics of the genetic material-is finally yielding meaningful results that give promise for understanding the regulation of gene activity. ROBERT F. GOLDBERGER Preface Research on the molecular mechanism作者: 母豬 時(shí)間: 2025-3-24 12:49 作者: 可耕種 時(shí)間: 2025-3-24 14:57
Intrathecal Cytokine Synthesis in Inflammatory and Demyelinating Diseases of the Central Nervous Sysors of lactotropes (GH., PRL.), the last cell type to appear along this lineage (Hoeffler et al., 1985; Behringer et al., 1988). Various data indicate the existence of a subpopulation of GH. cells which can switch to PRL. cells and PRL. cells which can switch to GH. cells, under the influence of cer作者: 心神不寧 時(shí)間: 2025-3-24 21:10
Lineages, Cell Fate Determination, and Migration in CNS Gliogenesisthe promoter and intron 1 leads to over-expression of . mRNA and an imbalance in production of the collagen type 1 α1 chain relative to the α2 chain. Polymorphisms in the regulatory regions of . and . have also been described which modulate gene expression, but the mechanisms by which these predispo作者: QUAIL 時(shí)間: 2025-3-25 03:02 作者: 熱情贊揚(yáng) 時(shí)間: 2025-3-25 06:58
Front Mattern, Alzheimer’s disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the populatio978-3-319-83893-9978-3-319-48078-7作者: 遷移 時(shí)間: 2025-3-25 09:27
Cellular and Molecular Characteristics of CNP Suggest Regulatory Mechanisms in Myelinogenesis978-1-4899-2760-6作者: CRUC 時(shí)間: 2025-3-25 12:04 作者: Ceramic 時(shí)間: 2025-3-25 19:43 作者: ineffectual 時(shí)間: 2025-3-25 21:52 作者: 大量 時(shí)間: 2025-3-26 00:38 作者: 內(nèi)閣 時(shí)間: 2025-3-26 06:23 作者: 偽書(shū) 時(shí)間: 2025-3-26 09:49 作者: 斜 時(shí)間: 2025-3-26 15:59 作者: 身體萌芽 時(shí)間: 2025-3-26 17:33 作者: 提升 時(shí)間: 2025-3-26 23:55 作者: APEX 時(shí)間: 2025-3-27 03:08
: Three New Members and Evidence for Their Common Origin from a Primitive Membrane Channelhenomena. The ideas fit well to observed data on the US obesity pandemic, its correlates of coronary heart disease, hypertension, and diabetes, and possibly to some cancers and autoimmune disorders. The model fits less well at the neighborhood scale, where multiple chronic diseases not only emerge, 作者: 樹(shù)木中 時(shí)間: 2025-3-27 05:37
Transgenic Models for Investigating Oligodendrocyte Differentiation and Myelin Formationological activities, such as cell proliferation, differentiation, adhesion, migration, and apoptosis. The TGF-β family members signal through transmembrane serine/threonine kinase receptors. Smads are major intracellular mediators that transduce the TGF-β signal from the cell surface to the nucleus.作者: 織物 時(shí)間: 2025-3-27 10:50
Axonal Contact Induces Oligodendroglial Specific Transcription of the , Gene from the Proximal Promotin America. The topic "Gene Expression and Its Regulation" was received enthusiastically, and, thanks to the vision of our Argentine colleagues, the program developed rapidly under the leadership of Dr. Gabriel Favelukes as General Secretary of the Symposium. It is interesting to note the tremendou作者: Alveolar-Bone 時(shí)間: 2025-3-27 14:09
Retrovirus-Mediated Gene Transfer of PMP22 in Schwann Cells: Studies on Cell Growthns reflect changes in gene expression that develop through a series of progressive events (4, 5; see also article by L.M. Franks in this volume). Working with the hypothesis that malignant transformation may be due to the abnormal expression of normal genes (6–10) we have carried out a detailed and 作者: 土坯 時(shí)間: 2025-3-27 20:08
Protein Sorting and Targeting in Myelin-Forming Schwann Cellsl components. Of the numerous cytoplasmic processes carried out by these biological catalysts, those that involve nucleic acid, in particular DNA, are crucial for cellular survival and, in the long term, for preservation of genetic information. Thus, although perturbation of a biosynthetic reaction 作者: Magisterial 時(shí)間: 2025-3-28 01:25
MOCH-1 Cells: An Oligodendrocyte Cell Line Generated Using a Transgenic Approach transcription induced by an external perturbation, such as gene overexpression/downregulation or treatment with a drug. Reverse-engineering algorithms based on ODEs require a choice of a functional form describing the effect of a regulator on its target genes. Here, we focused on an ODE-based rever作者: 本土 時(shí)間: 2025-3-28 05:44
Measles Virus Induced Autoimmune Reactions against Brain Antigenination of the bone marrow following therapy. The absence of obvious leukemic cells in a fully regenerated marrow defines remission. Unfortunately, leukemic blasts appear similar to normal early hematopoetic progenitors, which may be seen at a frequency of up to 5% of cells in normal marrow. Thus, t作者: Canyon 時(shí)間: 2025-3-28 08:47
Mechanisms of DE — and Remyelination in Autoimmune Encephalomyelitis and Multiple SclerosisOne particularly attractive model system for studying this hormonal regulation has been the hen oviduct (O’Malley et al. 1969). A number of laboratories, in addition to our own, have utilized this model system for investigations of eucaryotic molecular biology (Oka and Schimke 1969; Palmiter and Sch作者: Ingenuity 時(shí)間: 2025-3-28 13:59
The Immunologic Response of the Oligodendrocyte in the Active Multiple Sclerosis Lesion meantime. We have become comfortable with the totally unanticipated fact that the coding sequences of genes are in discontinuous arrangements and that the RNA transcribed from them must be extensively processed to form messenger RNA. We have also learned about the strategy of "mixing and matching" 作者: HUSH 時(shí)間: 2025-3-28 18:03
Autoimmune Responses to the Myelin Oligodendrocyte Glycoprotein (MOG) in the Pathogenesis of Inflammrganization nor the nuclear sites of action of these proteins is resolved. The questions that persist include the size and number of hormone-binding subunits of the holoreceptors and the means by which receptors are transformed* to tight chromatin-binding proteins in response to hormone treatment. W作者: 古董 時(shí)間: 2025-3-28 19:36
Intrathecal Cytokine Synthesis in Inflammatory and Demyelinating Diseases of the Central Nervous Sys that the difference between GH gene activity in somatotropes and hepatocytes exceeds 10.-fold (Ivarie et al, 1983). To achieve this level of control, a highly specific mechanism should restrict GH expression to the correct cell type. The GH-expressing somatotrope is derived from an acidophylic stem作者: Estimable 時(shí)間: 2025-3-28 23:06 作者: 有組織 時(shí)間: 2025-3-29 05:59 作者: Adornment 時(shí)間: 2025-3-29 07:31 作者: negotiable 時(shí)間: 2025-3-29 15:03
The Irish Community at Home and Abroad,tilamellar structure.. Myelin has a relatively simple protein composition, with the proteolipid (PLP) and DM20 proteins comprising approximately 50% of adult CNS myelin protein.. These proteins are translated from alternatively spliced mRNAs encoded by the PLP gene.. Thus, a major portion of the oli作者: 巧辦法 時(shí)間: 2025-3-29 16:49 作者: BRAND 時(shí)間: 2025-3-29 22:03
https://doi.org/10.1007/978-3-642-79603-6ropathies in mice and man has raised particular interest in the biological function of this gene (for review: Lemke, 1993; Suter et al., 1993). Due to the separate occasions leading to the identification of this gene different names have been given for PMP22 cDNAs in the literature. The reported cDN作者: 協(xié)迫 時(shí)間: 2025-3-30 02:54
https://doi.org/10.1007/978-3-642-79603-6anding how cells establish and maintain specialized surface membrane domains is a major challenge to cell biologists. Moreover, the failure to polarize surface membranes into specialized domains can have drastic effects on cell function and survival. Even the simplest cells can organize their surfac作者: ARY 時(shí)間: 2025-3-30 06:19
Paul Davidsson,Fredrik Wernstedtytes, these cells are the only ones to express it in the CNS. CNP is the earliest of all known myelination-related proteins to appear developmentally in oligodendrocytes; it accumulates in the cytoplasm-containing compartments of the myelin sheath, and is absent from compact lamellae.. Despite sever作者: 粉筆 時(shí)間: 2025-3-30 09:52 作者: OASIS 時(shí)間: 2025-3-30 13:09 作者: Glucose 時(shí)間: 2025-3-30 17:00 作者: aviator 時(shí)間: 2025-3-30 23:37
An Approach to Knowledge Base Managementic genetic programme. This process is also influenced by environmental factors and only the correct interaction of such factors makes possible the formation and the maintenance of the myelin sheath able to carry out its functional activities. Among environmental factors the important role of diet an作者: diathermy 時(shí)間: 2025-3-31 03:40
https://doi.org/10.1007/BFb0022001 formed when the myelinating cell wraps several layers of its cytoplasmic membrane around the axon. Compaction occurs as the cytoplasm is extruded from the multilayered structure and the cytoplasmic faces of the myelinating cell become juxtaposed. An electron micrograph of myelin reveals two types o作者: 撫慰 時(shí)間: 2025-3-31 05:48
Lecture Notes in Computer Scienceein by mass. This alone suggests an important structural function of PLP in compact myelin. More recently, the application of molecular genetic techniques by several groups has revealed an unexpected complex relationship between the PLP structure (a multitopic integral membrane protein) and its cell作者: Orthodontics 時(shí)間: 2025-3-31 12:37 作者: 試驗(yàn) 時(shí)間: 2025-3-31 16:17 作者: 安撫 時(shí)間: 2025-3-31 18:49 作者: Mettle 時(shí)間: 2025-4-1 00:04
An Approach to Knowledge Base Managementever the immune effector mechanisms responsible for the selective loss of myelin in MS have still to be defined. Several authors have suggested that demyelination in MS is simply a consequence of the local inflammatory response in the CNS, “bystander demyelination”. . studies demonstrating that olig
