標(biāo)題: Titlebook: Ways of Regulating Drugs in the 19th and 20th Centuries; Jean-Paul Gaudillière (Director),Volker Hess (Chai Book 2013 Palgrave Macmillan, [打印本頁(yè)] 作者: fathom 時(shí)間: 2025-3-21 19:50
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作者: Contracture 時(shí)間: 2025-3-21 23:53 作者: 轉(zhuǎn)向 時(shí)間: 2025-3-22 00:34 作者: 生氣地 時(shí)間: 2025-3-22 05:45
conds and span tens of thousands of servers within a data center or across geographically separated data centers. In this chapter, we shift our focus to another class of applications typically observed in a cloud platform, namely applications whose database and usage footprints are .. Such applicati作者: capsaicin 時(shí)間: 2025-3-22 11:00 作者: anthropologist 時(shí)間: 2025-3-22 14:31
Harry M. Marksthe increasing growth in deep learning and other AI applications has led to the emergence of custom Deep Neural Network (DNN) accelerators for energy-efficient inference on edge devices. Modern DNNs have millions of hyper parameters and involve billions of computations; this necessitates extensive d作者: gentle 時(shí)間: 2025-3-22 18:50
Volker Hessting from sequential to parallel computing. Unfortunately, improving performance of applications has now become much more difficult than in the good old days of frequency scaling. This is also affecting databases and data processing applications in general, and has led to the popularity of so-called作者: 松軟 時(shí)間: 2025-3-22 21:59 作者: 協(xié)議 時(shí)間: 2025-3-23 02:32
Axel C. Hüntelmannf these organizations‘ minds. Even though today several data security techniques are available to protect data and computing infrastructures, many such techniques -- such as firewalls and network security tools -- are unable to protect data from attacks posed by those working on an organization‘s "i作者: frozen-shoulder 時(shí)間: 2025-3-23 09:32 作者: 箴言 時(shí)間: 2025-3-23 11:47
Alberto Cambrosio,Peter Keating,Andrei Mogoutovectrum of this hot new profession. "Data scientist is the sexiest job in the 21st century," according to the .Harvard Business Review.. By 2018, the United States will experience a shortage of 190,000 skilled data scientists, according to a McKinsey report..Through incisive in-depth interviews, this作者: 別名 時(shí)間: 2025-3-23 14:51
Harry M. Marksral, a data stream is an unbounded data set that is produced incrementally over time, rather than being available in full before its processing begins. In this lecture, we give an overview of recent research in stream processing, ranging from answering simple queries on high-speed streams to loading作者: 躺下殘殺 時(shí)間: 2025-3-23 21:21
Jeremy A. Greeneting for transparency and access to current and historical datasets, has fundamentally transformed when, where, and how people encounter data. People now rely on data to make decisions, understand current events, and interpret the world. We frequently employ graphs, maps, and other spatialized forms作者: agenda 時(shí)間: 2025-3-24 00:48
Ilana L?wyssed in Chapter 3 and elsewhere in this book, real materials problems typically involve several components, are often solid solutions, and contain defects at . ≠ 0 and . ≠ 0. For crystals however, electronic structure calculations, say, based on density functional theory (DFT), often return reliable作者: 匍匐 時(shí)間: 2025-3-24 03:34
Viviane Quirkehance user understanding by combining the empathy inherent with personas with the rationality inherent in analytics using computational methods. Via the employment of these computational methods, the data-driven persona method permits the use of large-scale user data, which is a novel advancement in作者: 過(guò)份 時(shí)間: 2025-3-24 10:07 作者: Prognosis 時(shí)間: 2025-3-24 10:51
Alberto Cambrosio,Peter Keating,Andrei Mogoutov. They are employed in many domains of science such as bioinformatics, astronomy, and engineering. Such workflows usually present a considerable number of activities and activations (i.e., tasks associated with activities) and may need a long time for execution. Due to the continuous need to store a作者: 殘暴 時(shí)間: 2025-3-24 17:21 作者: Arable 時(shí)間: 2025-3-24 19:58 作者: 帶子 時(shí)間: 2025-3-25 00:17 作者: Cacophonous 時(shí)間: 2025-3-25 03:20
Toine Pieters,Stephen Sneldershey are used in corporate software development..Database Systems: A Pragmatic Approach. is a classroom textbook for use by students who are learning about relational databases, and the professors who teach them. It discusses the database as an essential component of a software system, as well as a v作者: BLANK 時(shí)間: 2025-3-25 09:17
Christian Bonahnd Facebook or financial markets) to big data analytics (e.g., scientific exploration, sensor networks, business intelligence). As a result, data management systems have been one of the main drivers for innovations in the database and computer architecture communities for several decades. Recent har作者: 感情 時(shí)間: 2025-3-25 12:01 作者: 小畫像 時(shí)間: 2025-3-25 15:51 作者: hermitage 時(shí)間: 2025-3-25 23:11
Toine Pieters,Stephen Snelderschnittsdaten vorgelegt. Das Buch versteht sich als Arbeitshilfe für fortgeschrittene Nutzer von SPSS und setzt sowohl Grundkenntnisse im Umgang mit dem Programm, insbesondere der Syntax voraus, wie auch Grundkenntnisse der Statistik und der Methoden der quantitativen empirischen Sozialforschung. Die作者: outer-ear 時(shí)間: 2025-3-26 03:44
Regulating Drugs, Regulating Diseases: Consumerism and the US Tolbutamide Controversy,errain in the regulation of medical practice and medical markets. In this chapter I will present a case study that succinctly illustrates some of the successes, failures, and lingering tensions surrounding these efforts.作者: IRATE 時(shí)間: 2025-3-26 04:53 作者: 業(yè)余愛好者 時(shí)間: 2025-3-26 11:41 作者: 過(guò)份好問 時(shí)間: 2025-3-26 15:54 作者: 情感脆弱 時(shí)間: 2025-3-26 20:32 作者: Conserve 時(shí)間: 2025-3-26 21:28 作者: onlooker 時(shí)間: 2025-3-27 01:33
Secrets, Bureaucracy, and the Public: Drug Regulation in Early 19th-Century Prussia,g drug market, and the expansion of state authority (Chauveau, 1999; Daemmrich, 2004; Bonah and Menut, 2004; L?wy and Gaudilliere, 2006). It may then seem strange to start a special volume on drug regulation with an analysis of drug approval starting in the early nineteenth century. Indeed, there ar作者: HEAVY 時(shí)間: 2025-3-27 07:21 作者: DEAWL 時(shí)間: 2025-3-27 09:30
Professional and Industrial Drug Regulation in France and Germany: The Trajectories of Plant Extrac discussion on the effects of industrialization on drug production and sales, the reform replaced the previous system — in which new remedies required professional approval from the Académie de Médecine — by establishing an administrative procedure for securing a .. This “visa” was the political rec作者: 調(diào)情 時(shí)間: 2025-3-27 17:38 作者: 詳細(xì)目錄 時(shí)間: 2025-3-27 18:56
Making Risks Visible: The Science, Politics, and Regulation of Adverse Drug Reactions,s linked to heart attacks. The scenarios involved in the recent cases of Baycol and Vioxx should be familiar. A novel drug passes intense regulatory scrutiny. The drug’s makers heavily promote it. Following widespread use, a previously unnoticed side effect is observed. Investigative journalists the作者: Admire 時(shí)間: 2025-3-28 01:52 作者: 一個(gè)姐姐 時(shí)間: 2025-3-28 02:14
Regulating Drugs, Regulating Diseases: Consumerism and the US Tolbutamide Controversy,ess.* Relatively little attention has been paid to the relationship between the regulation of drug products and the epidemiology and definition of the disease categories to which they are necessarily linked. As drugs have increasingly come to define diseases, and diseases to define drugs, the regula作者: Evolve 時(shí)間: 2025-3-28 09:06 作者: Excitotoxin 時(shí)間: 2025-3-28 10:25 作者: ALLEY 時(shí)間: 2025-3-28 16:30 作者: instate 時(shí)間: 2025-3-28 22:25
,What’s in a Pill? On the Informational Enrichment of Anti-Cancer Drugs, in orange, the words ., ., and . pointed to a tiny pile of orange pills identified in a smaller headline: “Revolutionary new pills like GLEEVEC combat cancer by targeting only the diseased cells. Is this the breakthrough we’ve been waiting for?” Two years later, Daniel Vasella, Chairman and CEO of 作者: placebo 時(shí)間: 2025-3-29 01:11
Making Risks Visible: The Science, Politics, and Regulation of Adverse Drug Reactions,s linked to heart attacks. The scenarios involved in the recent cases of Baycol and Vioxx should be familiar. A novel drug passes intense regulatory scrutiny. The drug’s makers heavily promote it. Following widespread use, a previously unnoticed side effect is observed. Investigative journalists the作者: 思想靈活 時(shí)間: 2025-3-29 06:35 作者: PET-scan 時(shí)間: 2025-3-29 10:21 作者: 終點(diǎn) 時(shí)間: 2025-3-29 11:37
Thalidomide, Drug Safety Regulation, and the British Pharmaceutical Industry: The Case of Imperial anagers, who have sometimes blamed the current dearth of new drugs on the increasingly complex and costly procedures involved in complying with the regulations imposed on them. As well as patenting, these have included pricing, and — most importantly — drug safety regulations. Indeed, as Gaudillière作者: 打包 時(shí)間: 2025-3-29 18:19
AZT and Drug Regulatory Reform in the Late 20th-Century US, story without reference to the rise of the AIDS epidemic and the efforts of AIDS activists. Their persistent calls for access to experimental drugs and changes in clinical protocol design for drug evaluation were highly influential in regulatory reforms implemented in the late 1980s and 1990s. On t作者: Chameleon 時(shí)間: 2025-3-29 20:28 作者: 思考 時(shí)間: 2025-3-30 00:07 作者: 控制 時(shí)間: 2025-3-30 05:03 作者: 彈藥 時(shí)間: 2025-3-30 12:07
Managing Double Binds in the Pharmaceutical Prescription Market: The Case of Halcion,e first decade of the twenty-first century has led to public debate on the integrity of the pharmaceutical industry and the effectiveness of drug regulation (Healy, 2004; Moynihan & Cassels, 2005; Anonymous, 2005; Committee on the assessment of the US drug safety system, 2006; Pray, 2007).. To impro作者: 忙碌 時(shí)間: 2025-3-30 15:15
Pharmaceutical Patent Law In-the-Making: Opposition and Legal Action by States, Citizens, and Gener endeavored to limit or suspend the extension of monopolies on remedies, in the interests of public health. In 1844 the French parliament, against the government’s advice, prohibited patents on medicines for a century. In this respect it followed the line of the Académie de Médecine, which at the ti作者: emission 時(shí)間: 2025-3-30 16:46 作者: Seminar 時(shí)間: 2025-3-30 22:19 作者: connoisseur 時(shí)間: 2025-3-31 03:24
Making Risks Visible: The Science, Politics, and Regulation of Adverse Drug Reactions, their product and their integrity while medical reformers and social scientists condemn corporate cupidity. Members of a bewildered public wonder about drug safety while injured patients and outraged politicians call for remedial action.作者: 下船 時(shí)間: 2025-3-31 08:55 作者: 來(lái)就得意 時(shí)間: 2025-3-31 12:06 作者: 騙子 時(shí)間: 2025-3-31 17:24
Jean-Paul Gaudillière (Director),Volker Hess (Chai作者: 具體 時(shí)間: 2025-3-31 20:10 作者: 放縱 時(shí)間: 2025-4-1 01:40
l since the individual tenants’ resource requirements are often small. In order to reduce the total cost of operation, cloud providers typically share resources among the tenants, a model referred to as .. Multi-tenancy is possible in all tiers of the cloud software stack: the web/application tier, 作者: 百科全書 時(shí)間: 2025-4-1 05:44
Harry M. Markst concludes with data orchestration challenges with compressed and sparse DNNs and future trends. The target audience is students, engineers, and researchers interested in designing high-performance and low-energy accelerators for DNN inference.978-3-031-00639-5978-3-031-01767-4Series ISSN 1935-3235 Series E-ISSN 1935-3243 作者: adroit 時(shí)間: 2025-4-1 09:13
Jeremy A. Greeneication of the various types of profilable metadata, discusses popular data profiling tasks,and surveys state-of-the-art profiling algorithms. While most of the book focuses on tasks and algorithms for relational data profiling, we also briefly discuss systems and techniques for profiling non-relati作者: 優(yōu)雅 時(shí)間: 2025-4-1 13:10 作者: 小淡水魚 時(shí)間: 2025-4-1 14:45
Alberto Cambrosio,Peter Keating,Andrei Mogoutovs); streaming television (Caitlin Smallwood, Netflix); music forecast (Victor Hu, Next Big Sound); strategic intelligence (Amy Heineike, Quid); environmental big data (André Karpi?t?enko., .Planet OS); geospatial marketing intelligence (Jonathan Lenaghan, PlaceIQ); advertising (Claudia Perlich, Dsti作者: DEMUR 時(shí)間: 2025-4-1 19:18
Harry M. Marks and using limited working memory. In the first part of this lecture, we will discuss research problems in DSMSs, such as continuous query languages, non-blocking query operators that continually react to new data, and continuous query optimization. The second part covers SDWs, which combine the rea作者: 喊叫 時(shí)間: 2025-4-2 02:41
Ilana L?wyly few well-characterized samples (between ten and in the hundreds) are available. Hence, it is important to consider approaches that we can tailor and use for small data sets. The relevant question then becomes how we can effectively learn from existing, limited data to guide the next experiments i作者: grandiose 時(shí)間: 2025-4-2 04:37
Viviane Quirke tools—data-driven personas! Using the data-driven approach, the persona profile can serve as an interface to a fully functional analytics system that can present user representation at various levels of information granularity for more task-aligned user insights. We trace the techniques that have e作者: Herpetologist 時(shí)間: 2025-4-2 09:51
Christian Bonahty gain due to subsequent noise reduction. To circumvent this problem, the method described in this chapter uses univariate microaggregation instead of its multivariate counterpart. As a result, utility gains with respect to standard differential privacy are obtained regardless of the number of reco作者: Brochure 時(shí)間: 2025-4-2 11:40 作者: 帳單 時(shí)間: 2025-4-2 15:20 作者: 演繹 時(shí)間: 2025-4-2 21:15 作者: EVADE 時(shí)間: 2025-4-2 23:41 作者: Herd-Immunity 時(shí)間: 2025-4-3 07:26
General Introduction,tion between Contergan and the rise of defects in newborns’ extremities appeared in the September 1961 edition of . — a suspicion that in the following weeks would be statistically substantiated by the pediatrician and geneticist Widukind Lenz. By the time the drug was recalled, however, in West Ger作者: Factual 時(shí)間: 2025-4-3 08:51
Secrets, Bureaucracy, and the Public: Drug Regulation in Early 19th-Century Prussia, rarely two or three substances. The effects are usually explained in physiological terms (aside from psychological effects, as with a placebo). Regulation is therefore about maximizing effectiveness, reducing toxicity, and avoiding adverse reactions, and involves state authorities, as well as profe作者: macabre 時(shí)間: 2025-4-3 15:28
Making Salvarsan: Experimental Therapy and the Development and Marketing of Salvarsan at the Crossrently tested for commercial reasons. In fact, on an occasion when Dreuw was lecturing at the Berlin Dermatological Society, the chairman tried to prevent him from speaking three times, but was unable to stop him.. Dreuw repeated his allegations over the following years, and although he was supported
