標(biāo)題: Titlebook: War in the Body; The Evolutionary Arm W David Wick,Otto O Yang Book 2013 Springer Science+Business Media New York 2013 Drug Resistance.HIV/ [打印本頁] 作者: broach 時(shí)間: 2025-3-21 17:31
書目名稱War in the Body影響因子(影響力)
書目名稱War in the Body影響因子(影響力)學(xué)科排名
書目名稱War in the Body網(wǎng)絡(luò)公開度
書目名稱War in the Body網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱War in the Body被引頻次
書目名稱War in the Body被引頻次學(xué)科排名
書目名稱War in the Body年度引用
書目名稱War in the Body年度引用學(xué)科排名
書目名稱War in the Body讀者反饋
書目名稱War in the Body讀者反饋學(xué)科排名
作者: HEED 時(shí)間: 2025-3-21 21:08
W. David Wick,Otto O. Yangoseph Priestley. The History and Present State of Electricity. It is generally considered bad form in writing, unless on matters autob- graphic,tomakeunbridleduseoftheperpendicularpronoun. Thereaderof the present book, however, may well wonder why one would want to study 1 the life and works of Thom作者: 1分開 時(shí)間: 2025-3-22 01:33 作者: PALMY 時(shí)間: 2025-3-22 07:05 作者: Mammal 時(shí)間: 2025-3-22 10:34
W. David Wick,Otto O. Yangced in the past few years, particularly the MPEG-1 and MPEG-2 for interactive multimedia and for digital NTSC and HDTV applications, and H.2611H.263 for video telecommunications. These techniques use motion estimation techniques to reduce the amount of data that is stored and transmitted for each fr作者: QUAIL 時(shí)間: 2025-3-22 13:25
W. David Wick,Otto O. Yangogy. Every volume in this series will deal with a topic of importance in computer science and elaborate on how you yourself can build systems related to the main theme. You will be able to develop a variety of systems, including computer software tools, computer graphics, computer animation, databas作者: 花爭吵 時(shí)間: 2025-3-22 19:36
W. David Wick,Otto O. Yangentific thought. As early as the fifth century B. C. questions regarding motion were presented as touchstones for the most fundamental concepts about existence. Such wide ranging philosophical issues are beyond the scope of this book, however, consider the paradox of the flying arrow attri- buted to作者: Mawkish 時(shí)間: 2025-3-22 21:30
W. David Wick,Otto O. Yangring November 21–24, 2009 in Zeist, The Netherlands. Games have become a very important medium for both education and - tertainment. Motion plays a crucial role in computer games. Characters move around, objects are manipulated or move due to physical constraints, entities are animated, and the came作者: LOPE 時(shí)間: 2025-3-23 01:22
W. David Wick,Otto O. Yangh, 1997, at the Solar Observatory Kanzelh6he, which belongs to the Astronomical Institute of the University of Graz, Austria. This type of conference has proved to be very successful in bringing together experts from specialized topics in solar physics and young scientists and students from differen作者: 墻壁 時(shí)間: 2025-3-23 07:51
W. David Wick,Otto O. Yang is the opposite of the question from which work on motivation began, and for which Claude Bernard invented the concept of the fixity of the internal milieu: How does an animal maintain constancy in the face of a fluctuating environment? Dealing with motivation has become extremely complex as new ex作者: 協(xié)議 時(shí)間: 2025-3-23 12:31
ing to carry across. In fact, it required many journeys both geographically, between Canada and Germany, and fig- uratively, between German and English language, thought, and culture; between the mind of a German professor and that of his American colleague. Whether or not it was all worthwhile must作者: 持續(xù) 時(shí)間: 2025-3-23 17:34 作者: 動(dòng)脈 時(shí)間: 2025-3-23 21:59 作者: 污穢 時(shí)間: 2025-3-24 00:27 作者: 全面 時(shí)間: 2025-3-24 03:35
W. David Wick,Otto O. Yang. It treats the BSIM3 model indetail as used in digital, analog and RF circuit design. It covers thecomplete set of models, i.e., I-V model, capacitance model, noisemodel, parasitics model, substrate current model, temperature effectmodel and non quasi-static model. ..MOSFET Modeling & BSIM3 User‘s 作者: monologue 時(shí)間: 2025-3-24 07:24
W. David Wick,Otto O. Yangly simple) result known as Bayes’s Theorem played a pivotal r? ole, and it struck me that it might be interesting to ?nd out a bit more about Thomas Bayes himself. In trying to satisfy this curiosity in spasmodic periods over many years I discovered that little information seemed to be available. Wr作者: floaters 時(shí)間: 2025-3-24 13:44
W. David Wick,Otto O. Yang publish my paper in full, such as it is given here as chapter 10. I am confident that no one will compare the two versions in order to try to find out \That has been left out in the earlier printing. Two other papers have appeared in German Festschrifts, one for Kurt Koster from Frankfurt-aiM (chap作者: FLIP 時(shí)間: 2025-3-24 15:19
W. David Wick,Otto O. Yangion analysis and image sequence processing, we like to place them in their proper contexts within the range of possible operations that involve image sequences. In this book, we choose to classify these operations into three major categories, namely (i) image sequence processing, (ii) image sequence作者: 放逐某人 時(shí)間: 2025-3-24 22:11
W. David Wick,Otto O. Yanggorithms, based on a number of experiments on several test video sequences, is presented as well. The theoretical framework for a new fast search algorithm, Densely-Centered Uniform-P Search (DCUPS), is developed and presented in the book. The complexity of the DCUPS algorithm is comparable to other作者: Chagrin 時(shí)間: 2025-3-25 02:56 作者: 半身雕像 時(shí)間: 2025-3-25 06:14
W. David Wick,Otto O. Yangn animal does what it does when it does. The book suffers from several omissions. There is no chapter on the devel- opment of motivated behavior. There is none on reward systems in the brain, owing to the untimely death of James Olds, whose contribution would have enriched this book appreciably, and作者: JAMB 時(shí)間: 2025-3-25 09:25 作者: Asymptomatic 時(shí)間: 2025-3-25 12:01 作者: 確定無疑 時(shí)間: 2025-3-25 16:24
W. David Wick,Otto O. Yange arrow comprising a sequence of positions at which the arrow is at rest. The original intent of presenting this paradox has been interpreted to be as an argume978-1-4612-8413-0978-1-4613-1071-6Series ISSN 0893-3405 作者: 羽毛長成 時(shí)間: 2025-3-25 22:02 作者: 混雜人 時(shí)間: 2025-3-26 02:27
W. David Wick,Otto O. Yang‘s climate were addressed. The main lec- tures were given by 7 lecturers. Furthermore, there were 20 contributions to the workshop which were presented in oral 978-90-481-5151-6978-94-015-9331-1Series ISSN 0067-0057 Series E-ISSN 2214-7985 作者: 苦笑 時(shí)間: 2025-3-26 07:48
W. David Wick,Otto O. YangJi is search- ing and profound. And, most recent of all, a book by William T. Black- stone has appeared entitled Francis Hutcheson and Contemporary Ethi- cal Th978-94-010-2973-5978-94-010-2971-1Series ISSN 0066-6610 Series E-ISSN 2215-0307 作者: Electrolysis 時(shí)間: 2025-3-26 11:52 作者: 猛然一拉 時(shí)間: 2025-3-26 16:23 作者: Adulate 時(shí)間: 2025-3-26 19:23
species (or variants thereof) that compete?for niches or resources in a fixed, unreactive environment. Both models will be formulated?using mathematical models, which will be included in the book. Finally, it will consider the possibilities for designing a vaccine that blocks HIV from escaping the immune system.978-1-4899-9255-0978-1-4614-7294-0作者: Disk199 時(shí)間: 2025-3-27 00:48 作者: LIMIT 時(shí)間: 2025-3-27 01:47 作者: 暫時(shí)休息 時(shí)間: 2025-3-27 06:17 作者: CANDY 時(shí)間: 2025-3-27 12:51 作者: Gorilla 時(shí)間: 2025-3-27 15:12 作者: 消音器 時(shí)間: 2025-3-27 19:06
The Escape Formulacs, we must distinguish two contributions to viral fitness: one relating to the ability of HIV to grow in its target cells, independent of any immune response, and another reflecting immune pressure. Both appear in a heuristic formula for the rate of escape from CTL control, which we describe in this chapter.作者: 宣稱 時(shí)間: 2025-3-27 22:21 作者: 跳動(dòng) 時(shí)間: 2025-3-28 04:48 作者: Incommensurate 時(shí)間: 2025-3-28 08:52
The CTL Model lymph nodes and other tissues, where they patrol for cells infected by pathogens. Each T-cell recognizes a specific antigen, which in our context is an “epitope”, a short segment of an HIV protein in a complex with an HLA molecule, exposed on the surface of an infected cell. T-cells that have not e作者: FACET 時(shí)間: 2025-3-28 12:47 作者: overwrought 時(shí)間: 2025-3-28 18:26
The Escape Formulatatic environment. The environment of HIV . is not static, but dynamic and reactive, so topographical imagery is dubious. Also unlike classical genetics, we must distinguish two contributions to viral fitness: one relating to the ability of HIV to grow in its target cells, independent of any immune 作者: 洞穴 時(shí)間: 2025-3-28 19:54 作者: 流動(dòng)才波動(dòng) 時(shí)間: 2025-3-28 22:58 作者: 希望 時(shí)間: 2025-3-29 03:04 作者: 躺下殘殺 時(shí)間: 2025-3-29 10:00
More Topics About Escape from Immune Controlknow epitopes delivered by the injection. (In natural infection, the average number of responses is around 19; as many as 42 have been observed in a single patient.) Many theories have been elaborated for this surprising and, from the insights about escape arising from the Escape Formula, unfortunat作者: FOVEA 時(shí)間: 2025-3-29 11:25 作者: 啟發(fā) 時(shí)間: 2025-3-29 17:34 作者: Inculcate 時(shí)間: 2025-3-29 23:32
Can a T-Cell Vaccine Block Escape? scab, then with smallpox), scientists have tested a plethora of vaccine concepts. Louis Pasteur discovered, somewhat by accident, the first “l(fā)ive-attenuated” vaccine (it was an aging culture of fowl cholera), a weakened preparation of the disease agent that still replicates in the host and generate作者: Impugn 時(shí)間: 2025-3-30 02:35
Can a T-Cell Vaccine Block Escape? scab, then with smallpox), scientists have tested a plethora of vaccine concepts. Louis Pasteur discovered, somewhat by accident, the first “l(fā)ive-attenuated” vaccine (it was an aging culture of fowl cholera), a weakened preparation of the disease agent that still replicates in the host and generate作者: 損壞 時(shí)間: 2025-3-30 06:20
Book 2013e the discussion about something other than viruses, said variants could easily be classified as different?species. This book will consider these evolutionary variations, as well as the different and, at times, opposing theories attempting to explain them. It will compare and contrast the ways in wh作者: Torrid 時(shí)間: 2025-3-30 12:05
978-1-4899-9255-0Springer Science+Business Media New York 2013作者: Mundane 時(shí)間: 2025-3-30 14:38 作者: Conclave 時(shí)間: 2025-3-30 18:58
https://doi.org/10.1007/978-1-4614-7294-0Drug Resistance; HIV/AIDS; Viral Evolution; vaccines作者: defuse 時(shí)間: 2025-3-30 22:01 作者: 改正 時(shí)間: 2025-3-31 04:50
Simulating an HIV Infection ,When the HIV and CTL models are combined, we have gone beyond familiar textbook examples of biological modeling. Although mathematics provides insights into the predictions of the model (described in subsequent chapters), to some extent we must rely on computer simulation.作者: CLOWN 時(shí)間: 2025-3-31 08:17 作者: 尖叫 時(shí)間: 2025-3-31 10:08
Simulating an HIV Infection ,When the HIV and CTL models are combined, we have gone beyond familiar textbook examples of biological modeling. Although mathematics provides insights into the predictions of the model (described in subsequent chapters), to some extent we must rely on computer simulation.作者: 音樂學(xué)者 時(shí)間: 2025-3-31 13:54 作者: admission 時(shí)間: 2025-3-31 19:06
Understanding EscapeIn this chapter, we discuss consequences of the Escape Formula and inte-resting discoveries we made by simulating escapes under the immune-control model.作者: 豎琴 時(shí)間: 2025-4-1 01:33
Early and Late EscapesThe immune-control hypothesis, as we explained in the Introduction, leads to a very different picture of HIV evolution . than that of traditional population genetics. In this chapter, we compare the explanations for escapes derived from the two approaches.作者: 挑剔小責(zé) 時(shí)間: 2025-4-1 05:04
Understanding EscapeIn this chapter, we discuss consequences of the Escape Formula and inte-resting discoveries we made by simulating escapes under the immune-control model.作者: 兵團(tuán) 時(shí)間: 2025-4-1 06:36
HIV’s Cloaking Device: The Fascinating Story of NefMost pathogens have evolved some mechanism for partially or wholly evading host immune responses. In the case of HIV, the prominent deceiver is a virally-encoded protein called Nef.作者: LUT 時(shí)間: 2025-4-1 14:02
HIV’s Cloaking Device: The Fascinating Story of NefMost pathogens have evolved some mechanism for partially or wholly evading host immune responses. In the case of HIV, the prominent deceiver is a virally-encoded protein called Nef.作者: 厭食癥 時(shí)間: 2025-4-1 18:18 作者: Amenable 時(shí)間: 2025-4-1 21:00
Retroviral Sex and EscapeIn the late 1960s, virologists made the surprising discovery that retroviruses exhibit a form of sexual reproduction. Humans are genetically “diploid”, which means that, except in germline cells, they maintain two sets of genetic information (in DNA, on paired chromosomes), and of course they reproduce sexually.作者: tariff 時(shí)間: 2025-4-2 02:35
The STEP Trial, Monkey Trials, and the Future of T-Cell VaccinesOn September 21, 2007, the world’s first large clinical trial. of a T-cell vaccine for HIV/AIDS was terminated prematurely by the Data Safety and Monitoring Board (DSMB).作者: intuition 時(shí)間: 2025-4-2 05:49
The STEP Trial, Monkey Trials, and the Future of T-Cell VaccinesOn September 21, 2007, the world’s first large clinical trial. of a T-cell vaccine for HIV/AIDS was terminated prematurely by the Data Safety and Monitoring Board (DSMB).作者: jagged 時(shí)間: 2025-4-2 08:39 作者: Mast-Cell 時(shí)間: 2025-4-2 14:38
Afterword: The RV144 Trial and the Current Status of HIV Vaccine ResearchThe long history of vaccine development, starting with observations about cowpox and smallpox, has been mainly empirical. The two biggest pioneers of modern vaccines, Salk and Sabin, were proponents of two competing strategies: kill or weaken the pathogen, and mimic infection without disease.作者: Oafishness 時(shí)間: 2025-4-2 16:20
Short Tutorial on Dynamical ModelsA . is a mathematical description of a number of ., which in biology are non-negative quantities describing populations of molecules, viruses, cells, or organisms, and a single ., namely time.作者: 粗糙 時(shí)間: 2025-4-2 22:52
Short Tutorial on Dynamical ModelsA . is a mathematical description of a number of ., which in biology are non-negative quantities describing populations of molecules, viruses, cells, or organisms, and a single ., namely time.作者: guzzle 時(shí)間: 2025-4-3 02:17 作者: FIS 時(shí)間: 2025-4-3 05:45 作者: paltry 時(shí)間: 2025-4-3 10:35
The Infection Model DefinedThe number of epitopes recognizable by CTLs will be denoted by . (not to be confused with mathematical expectation, which will be denoted . if required).作者: 健談 時(shí)間: 2025-4-3 12:09
The Infection Model DefinedThe number of epitopes recognizable by CTLs will be denoted by . (not to be confused with mathematical expectation, which will be denoted . if required).