標(biāo)題: Titlebook: 25 Years of p53 Research; Pierre Hainaut,Klas G. Wiman Book 2005 Springer Science+Business Media B.V. 2005 DNA.P53, Wiman, Hainaut, tumor [打印本頁] 作者: Intimidate 時間: 2025-3-21 17:31
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書目名稱25 Years of p53 Research網(wǎng)絡(luò)公開度學(xué)科排名
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書目名稱25 Years of p53 Research被引頻次學(xué)科排名
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書目名稱25 Years of p53 Research年度引用學(xué)科排名
書目名稱25 Years of p53 Research讀者反饋
書目名稱25 Years of p53 Research讀者反饋學(xué)科排名
作者: babble 時間: 2025-3-21 23:17
https://doi.org/10.1007/978-3-031-01666-0inely as predictive markers for tumor response to anti-hormone therapy. However, about 30 % of patients with positive receptor status (expected to benefit from anti-hormone treatment) will face a therapeutic failure, showing the limitations of these markers.作者: 乞丐 時間: 2025-3-22 01:58 作者: Alveoli 時間: 2025-3-22 08:22
Heterogeneous Buffering for 3D NoCsne, or, in fact, predecessors of this famed ‘guardian of the genome’? . studies clearly reveal distinct physiological roles for p53, p63, and p73. But do these belie cooperative or antagonistic interactions within the p53 gene family?作者: 笨重 時間: 2025-3-22 10:55
https://doi.org/10.1007/978-3-030-96794-9as not been demonstrated, and p53 tumor suppressor activity may not require the acute p53 response to DNA damage (Komarov et al., 1999). Nonetheless, the genotoxic chemicals and ionizing radiation that are clinically used to treat human cancer indisputably activate wild type p53.作者: 一瞥 時間: 2025-3-22 13:03 作者: 沙發(fā) 時間: 2025-3-22 20:09 作者: 警告 時間: 2025-3-22 23:17 作者: Ccu106 時間: 2025-3-23 01:29
Book 2005of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. Review arcticles, despite their fundamental role in disseminating knowledge, usually focus only on general mechan作者: 清唱劇 時間: 2025-3-23 06:39
https://doi.org/10.1007/978-3-030-96794-9 genetics in cancer research. I therefore arranged to visit Arnie’s lab to learn more about his research program. We discussed many topics, but not about how the large transforming protein (T antigen) of SV40 (SV40TAg) interacted with a putative ~54kDα cellular protein (Linzer and Levine, 1979).作者: 憤怒歷史 時間: 2025-3-23 12:54
Introduction to 3D Technologieson known as Li-Fraumeni syndrome1 is linked to germ-line mutation of the p53 gene (for a review see Varley et al., 1997), and by the clear tumour propensity shown by p53 knock-out mice (for a review see Venkatachalam and Donehower, 1998).作者: euphoria 時間: 2025-3-23 14:21
https://doi.org/10.1007/978-3-031-01666-0ytotoxic therapies, for example, rely on the introduction of DNA damage or the inhibition of chromosome segregation. These lesions, when introduced at high levels, elicit a DNA damage response presumably distinct from any encountered during the early stages of tumor development.作者: 暴發(fā)戶 時間: 2025-3-23 21:29
Lucia Knap?íková,Dragan Perakovi?s among these observations were not apparent. Fifty years of research had demonstrated that viruses with both DNA and RNA genomes could cause cancer in animals. Over the next 45 years six new viruses were to be discovered that were able to initiate cancers in humans (Epstein-Barr Virus, Human T-Cell作者: Allodynia 時間: 2025-3-24 01:28 作者: apropos 時間: 2025-3-24 05:35 作者: Optimum 時間: 2025-3-24 09:16 作者: beta-carotene 時間: 2025-3-24 14:39 作者: Outshine 時間: 2025-3-24 18:32 作者: 軟膏 時間: 2025-3-24 22:25 作者: Aesthete 時間: 2025-3-25 01:46
Heterogeneous Buffering for 3D NoCsgnaling, stress response, cell cycle control, and apoptosis are a result of these . studies (Giaccia and Kastan, 1998; Ko and Prives, 1996; Levine, 1997; Vogelstein et al., 2000). However, a greater depth of understanding was facilitated by the advent first of transgenic mouse methodologies and then作者: Transfusion 時間: 2025-3-25 05:28
Heterogeneous Buffering for 3D NoCsversy and debate. Do these homologs behave like p53? Do they also act in tumor suppression? What were their origins – spin-offs of an ancestral p53 gene, or, in fact, predecessors of this famed ‘guardian of the genome’? . studies clearly reveal distinct physiological roles for p53, p63, and p73. But作者: 蚊子 時間: 2025-3-25 10:43 作者: 帶傷害 時間: 2025-3-25 15:25
Introduction to 3D Technologieshe fact that the normally low levels of the p53 protein can be elevated in many cancers, it took some time to realise that p53 was in fact a tumour suppressor gene (Finlay et al., 1989; Levine et al., 1991). This concept was further consolidated by the discovery that the familial cancer predispositi作者: STING 時間: 2025-3-25 17:21
Introduction to 3D TechnologiesMoll and Schramm, 1998), are just a few of the names that have been attributed to the p53 gene over recent years. However, the cameras (and funding) were certainly not present at the time of the discovery of p53 in 1979 (Crawford, 1983). It was only when the first alterations of the p53 gene in huma作者: MULTI 時間: 2025-3-25 19:58 作者: 發(fā)芽 時間: 2025-3-26 03:59 作者: Redundant 時間: 2025-3-26 04:34 作者: Aerophagia 時間: 2025-3-26 10:08
Zhenyu Xu,YeTong Wu,JunHong Zhongom/infotp.html; http;//www.sibiono.com) and p53 gene therapy gained regulatory approval in China in 2003 where it has been on sale since January 2004. Renewed optimism around the use of p53 gene therapy and increased understanding of p53 function suggest that many more potent and selective variants 作者: 思考而得 時間: 2025-3-26 13:15 作者: 他一致 時間: 2025-3-26 19:16
6GN for Future Wireless Networksion database at http://www.iarc.fr/p53). A majority of p53 mutations are missense mutations that give rise to the expression of mutant p53 proteins with one amino acid substitution. This pattern of mutation stands in sharp contrast to those of most other tumor suppressor genes, e.g. the Rb and p16 g作者: 發(fā)現(xiàn) 時間: 2025-3-26 23:00 作者: 真 時間: 2025-3-27 01:31
Pierre Hainaut,Klas G. Wimanp53 is considered the most important cancer gene.p53 is a target for novel cancer therapy strategies already underway.p53 works as a sensor of oncogenic environmental stress.Written by world-leading s作者: 外來 時間: 2025-3-27 05:31 作者: Culmination 時間: 2025-3-27 09:58
https://doi.org/10.1007/978-1-4020-2922-6DNA; P53, Wiman, Hainaut, tumor suppressor genes, apoptosis, muta; apoptosis; biology; cancer; cancer res作者: 落葉劑 時間: 2025-3-27 14:32 作者: companion 時間: 2025-3-27 21:00 作者: Esophagus 時間: 2025-3-28 00:10 作者: 歌曲 時間: 2025-3-28 05:56 作者: 懶惰民族 時間: 2025-3-28 09:29
Gatekeepers of the Guardian: p53 Regulation by Post-Translational Modification, MDM2 and MDMX,ut physical beauty in Byzantium? As we redress the imbalance between the ascetic body and the sensual body in the Byzantine world, the image of physical beauty and the Byzantine views, stereotypes, beliefs and attitudes surrounding the beautiful body emerge as grounds for discussion.作者: 我不死扛 時間: 2025-3-28 13:06
Regulation of the p53 Response by Cellular Growth and Survival Factors,ndrously youthful outcome may not be met through surgery, but recompense through law requires a failure of surgical technique, not patient or client dissatisfaction. As for teeth, whitening and false crowns or veneers can make a smile translucent or lead to litigation with enamel stripped, gums dise作者: 四溢 時間: 2025-3-28 17:25 作者: 使閉塞 時間: 2025-3-28 21:07 作者: 河潭 時間: 2025-3-29 00:43 作者: 音的強弱 時間: 2025-3-29 07:01
P53, P63, and P73: Internecine Relations?, agencies — they are equally enforcers and perpetrators of the adamant(ine) western male ego-state, determined to suppress the demonic (dream, the shamanic encounter with the Great Goddess, similar a-logical states) and to promulgate an illusion of humanist autonomy as antidote to madness. As Paglia作者: 艦旗 時間: 2025-3-29 10:23
P73, P63 and Mutant P53: Members of Protein Complexs Floating in Cancer Cells,itative flux. Real time is a continuous, non-segmentable stream which cannot be captured or framed with mechanistic concepts. According to Bergson, ‘there is no feeling, no idea, no volition which is not undergoing change every moment: if a mental state ceased to vary, its duration would cease to fl作者: 嚴峻考驗 時間: 2025-3-29 13:11
P53: Gatekeeper, Caretaker or Both?,witz confirmed [.] the philosopheme of pure identity as death’ (Adorno 1973, 362). if one accepts Adorno’s contention, then however radically one might tamper with the commonsense notion of history as a more or less coherent diachronic sequence, and even if one defines the postmodern, as Lyotard doe作者: fastness 時間: 2025-3-29 15:37
Analysis of p53 Gene Alterations in Cancer: A Critical View,very last thing I wrote — ?Textes pour rien? — was an attempt to get out of the attitude of disintegration, but it failed.? [2] Wenn also der Versuch der . gescheitert sein soll, aus der Desintegration herauszukommen, dann — so darf man schlie?en — werden ihre Darstellungen der Desintegration als ei作者: CRUC 時間: 2025-3-29 22:11 作者: 失望昨天 時間: 2025-3-30 02:51
Novel p53-Based Therapies: Strategies and Future Prospects,the course of a week, even while workingyour day job, you will be prepared to take the exam..What You Will Learn.Know the basics of ITIL as you prepare for the ITIL Foundation certification exam.Understand ITIL through examples.Be aware of ITIL‘s relevance to DevOps and DevOps concepts.Who This Book作者: 容易做 時間: 2025-3-30 04:10
Wild Type p53 Conformation, Structural Consequences of p53 Mutations and Mechanisms of Mutant p53 Rs of social inclusion and political participation. In online chats and rap songs, they often convey a double feeling of estrangement towards host populations in the places they have crossed or where they currently reside, but also towards their kith and kin in the places they have left. They also ta作者: BRUNT 時間: 2025-3-30 12:00 作者: 紅腫 時間: 2025-3-30 13:13 作者: 枯萎將要 時間: 2025-3-30 18:12
Prognostic and Predictive Value of TP53 Mutations in Human Cancer,978-0-230-23947-0作者: 可用 時間: 2025-3-30 23:04 作者: angina-pectoris 時間: 2025-3-31 04:21
Lucia Knap?íková,Dragan Perakovi?scientists thought to find a common ground between concepts generated in each field. Thirdly, the study of mouse genetics demonstrated that some cancers were clearly inherited and these observations confirmed many prior publications that suggested a role for cancer causing genes in humans and other 作者: LOPE 時間: 2025-3-31 05:46
Lecture Notes in Mechanical Engineering much research has focused on understanding this crucial ability as well as its regulation. Indeed, the regulation of p53 DNA binding has generated much debate recently, specifically with regard to the role of the C-terminus.作者: nonplus 時間: 2025-3-31 09:48
Pragmatic Performance Managementvation of p53 in normal tissues, however, can lead to tissue damage and has been associated with multiple sclerosis (Wosik et al., 2003), neurodegenerative disorders and exacerbation of ischemic damage from stroke or cardiac arrest (Mattson et al., 2001; Komarova and Gudkov, 2001). Accordingly, the 作者: 吊胃口 時間: 2025-3-31 13:40
